ATE323531T1 - Verwendung von nk-1-rezeptorantagonisten gegen benigne prostatahyperplasie - Google Patents

Verwendung von nk-1-rezeptorantagonisten gegen benigne prostatahyperplasie

Info

Publication number: ATE323531T1
Authority: AT; Austria
Prior art keywords: benigne; receptor antagonists; prostate hyperplasia; antagonists against; hyperplasia
Prior art date: 2001-04-23

Application number

AT02719751T

Other languages

English (en)

Inventor

Susanne Buser

Anthony P D W Ford

Torsten Hoffmann

Barbara Lenz

Andrew John Sleight

Pierre Vankan

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-23

Filing date

2002-02-02

Publication date

2006-05-15

2002-02-02 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2006-05-15 Application granted granted Critical

2006-05-15 Publication of ATE323531T1 publication Critical patent/ATE323531T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT02719751T 2001-04-23 2002-02-02 Verwendung von nk-1-rezeptorantagonisten gegen benigne prostatahyperplasie ATE323531T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01109853		2001-04-23

Publications (1)

Publication Number	Publication Date
ATE323531T1 true ATE323531T1 (de)	2006-05-15

Family

ID=8177209

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02719751T ATE323531T1 (de)	2001-04-23	2002-02-02	Verwendung von nk-1-rezeptorantagonisten gegen benigne prostatahyperplasie

Country Status (17)

Country	Link
US (1)	US20030004157A1 (de)
EP (1)	EP1385577B1 (de)
JP (1)	JP4146730B2 (de)
KR (1)	KR100599134B1 (de)
CN (1)	CN100398106C (de)
AR (1)	AR035935A1 (de)
AT (1)	ATE323531T1 (de)
AU (1)	AU2002250876B2 (de)
BR (1)	BR0209151A (de)
CA (1)	CA2444395C (de)
DE (1)	DE60210760T2 (de)
DK (1)	DK1385577T3 (de)
ES (1)	ES2261657T3 (de)
MX (1)	MXPA03009720A (de)
PT (1)	PT1385577E (de)
WO (1)	WO2002085458A2 (de)
ZA (1)	ZA200308110B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2002259147A1 (en) *	2001-05-08	2002-11-18	Schering Corporation	Use of neurokinin receptor antagonists to treat androgen-dependent diseases
US6849624B2 (en)	2001-07-31	2005-02-01	Hoffmann-La Roche Inc.	Aromatic and heteroaromatic substituted amides
PL378404A1 (pl) *	2003-01-31	2006-04-03	F. Hoffmann-La Roche Ag	Nowa odmiana krystaliczna 2-(3,5-bis-trifluorometylofenylo)-N-[6-(1,1-diokso-1<$Elambda>6 -tiomorfolin-4-ylo)-4-(4-fluoro-2-metylofenylo)pirydyn-3-ylo]-N-metyloizobutyroamidu
HRP20070471T3 (hr) *	2003-07-03	2007-11-30	F. Hoffmann - La Roche Ag	Dvojni nk1/nk3 antagonisti za liječenje shizofrenije
ES2246687B2 (es) *	2004-02-11	2006-11-16	Miguel Muñoz Saez	Utilizacion de antagonistas no peptidicos de receptores nk1 para la produccion de apoptosis en celulas tumorales.
MX2007000198A (es)	2004-07-06	2007-03-15	Hoffmann La Roche	Proceso para la preparacion de derivados de carboxamida-piridina utilizados como intermediarios en la sintesis de antagonistas del receptor nk-1.
US20060030600A1 (en) *	2004-08-06	2006-02-09	Patrick Schnider	Dual NK1/NK3 receptor antagonists for the treatment of schizophrenia
BRPI0606187A2 (pt)	2005-02-25	2009-06-09	Hoffmann La Roche	comprimidos com capacidade de dispersão da substáncia do fármaco melhorada
DK2395002T3 (da)	2005-11-08	2014-09-08	Vertex Pharma	Farmaceutisk sammensætning indeholdende en heterocyclisk modulator af ATP-bindende kassettetransportører
US7671221B2 (en)	2005-12-28	2010-03-02	Vertex Pharmaceuticals Incorporated	Modulators of ATP-Binding Cassette transporters
US7754739B2 (en)	2007-05-09	2010-07-13	Vertex Pharmaceuticals Incorporated	Modulators of CFTR
JP2010516731A (ja)	2007-01-24	2010-05-20	グラクソグループリミテッド	２−メトキシ−５−（５−トリフルオロメチル−テトラゾール−１−イル）−ベンジル］−（２ｓ−フェニル−ピペリジン−３ｓ−イル）−アミンを含む医薬組成物
CN102863432B (zh)	2007-05-09	2016-09-07	沃泰克斯药物股份有限公司	Cftr调节剂
MX2010006183A (es)	2007-12-07	2010-10-15	Vertex Pharma	Procesos para producir acidos cicloalquilcarboxamido-piridin benzoicos.
SG186638A1 (en)	2007-12-07	2013-01-30	Vertex Pharma	Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid
NZ703814A (en)	2008-02-28	2016-06-24	Vertex Pharma	Heteroaryl derivatives as cftr modulators
GB0808747D0 (en)	2008-05-14	2008-06-18	Glaxo Wellcome Mfg Pte Ltd	Novel compounds
RU2011141794A (ru)	2009-03-17	2013-04-27	Дайити Санкио Компани, Лимитед	Амидное производное
WO2010119347A1 (en) *	2009-04-14	2010-10-21	Helsinn Healthcare S.A.	Netupitant for use in treating bladder dysfunction
EP2493299A4 (de) *	2009-10-29	2013-04-17	Merck Sharp & Dohme	Tertiäre amidorexinrezeptorantagonisten
CN106943403A (zh)	2010-04-07	2017-07-14	弗特克斯药品有限公司	药物组合物和其给药方法
PL2806859T3 (pl)	2012-01-25	2019-11-29	Vertex Pharma	Formulacje kwasu 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5- ilo)cyklopropanokarboksyamido)-3-metylopirydyn-2-ylo)benzoesowego
KR20160078997A (ko)	2013-11-08	2016-07-05	깃세이 야쿠힌 고교 가부시키가이샤	카복시메틸피페리딘 유도체
PT3068392T (pt)	2013-11-12	2021-05-14	Vertex Pharma	Processo de preparação de composições farmacêuticas para o tratamento de doenças mediadas por condutância transmembrana da fibrose quística (cftr)
TWI649307B (zh)	2014-05-07	2019-02-01	日商橘生藥品工業股份有限公司	Cyclohexylpyridine derivative
CN107110831B (zh)	2014-11-18	2020-02-21	弗特克斯药品有限公司	进行高通量试验高效液相色谱的方法
WO2019148246A1 (en) *	2018-02-02	2019-08-08	Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro)	Parenteral formulations and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6175013B1 (en) *	1994-06-10	2001-01-16	Eli Lilly And Company	Imidazolinyl tachykinin receptor antagonists
FR2729951B1 (fr) *	1995-01-30	1997-04-18	Sanofi Sa	Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
HRP20000065A2 (en) *	1997-08-06	2001-04-30	Lilly Co Eli	2-acylaminopropanamines as tachykinin receptor antagonists
PL338456A1 (en) *	1997-08-06	2000-11-06	Lilly Co Eli	2-acylaminopropanoamines as antagonists of the tachykinin receptor
JPH11322748A (ja) *	1998-03-19	1999-11-24	Takeda Chem Ind Ltd	複素環化合物、その製造法および用途
ES2226622T3 (es) *	1999-02-24	2005-04-01	F. Hoffmann-La Roche Ag	Derivados de 4-fenil piridina y su empleo como antagonistas del receptor nk-1.
AU3735000A (en) *	1999-05-05	2000-11-21	Warner-Lambert Company	Modulation of substance p by gaba analogs and methods relating thereto
HU230316B1 (hu) *	2000-07-14	2016-01-28	F. Hoffmann-La Roche Ag	N-oxidok, mint 4-fenil-piridin-származékok előgyógyszerei, eljárás és előállításukra és az ezeket tartalmazó gyógyszerkészítmények
US6849624B2 (en) *	2001-07-31	2005-02-01	Hoffmann-La Roche Inc.	Aromatic and heteroaromatic substituted amides

2002
- 2002-02-02 MX MXPA03009720A patent/MXPA03009720A/es active IP Right Grant
- 2002-02-02 DK DK02719751T patent/DK1385577T3/da active
- 2002-02-02 DE DE60210760T patent/DE60210760T2/de not_active Expired - Lifetime
- 2002-02-02 CN CNB028087305A patent/CN100398106C/zh not_active Expired - Lifetime
- 2002-02-02 EP EP02719751A patent/EP1385577B1/de not_active Expired - Lifetime
- 2002-02-02 KR KR1020037013798A patent/KR100599134B1/ko not_active Expired - Lifetime
- 2002-02-02 AU AU2002250876A patent/AU2002250876B2/en not_active Expired
- 2002-02-02 PT PT02719751T patent/PT1385577E/pt unknown
- 2002-02-02 AT AT02719751T patent/ATE323531T1/de active
- 2002-02-02 CA CA2444395A patent/CA2444395C/en not_active Expired - Lifetime
- 2002-02-02 BR BR0209151-8A patent/BR0209151A/pt not_active Application Discontinuation
- 2002-02-02 ES ES02719751T patent/ES2261657T3/es not_active Expired - Lifetime
- 2002-02-02 WO PCT/EP2002/001085 patent/WO2002085458A2/en not_active Ceased
- 2002-02-02 JP JP2002583031A patent/JP4146730B2/ja not_active Expired - Lifetime
- 2002-02-07 AR ARP020100393A patent/AR035935A1/es unknown
- 2002-02-08 US US10/071,570 patent/US20030004157A1/en not_active Abandoned
2003
- 2003-10-17 ZA ZA2003/08110A patent/ZA200308110B/en unknown

Also Published As

Publication number	Publication date
WO2002085458A2 (en)	2002-10-31
CA2444395A1 (en)	2002-10-31
ES2261657T3 (es)	2006-11-16
EP1385577B1 (de)	2006-04-19
US20030004157A1 (en)	2003-01-02
CA2444395C (en)	2010-12-21
AU2002250876B2 (en)	2005-03-03
CN100398106C (zh)	2008-07-02
DK1385577T3 (da)	2006-08-21
WO2002085458A3 (en)	2003-10-30
ZA200308110B (en)	2005-03-30
DE60210760D1 (de)	2006-05-24
MXPA03009720A (es)	2004-01-29
KR100599134B1 (ko)	2006-07-12
EP1385577A2 (de)	2004-02-04
PT1385577E (pt)	2006-08-31
CN1503684A (zh)	2004-06-09
JP4146730B2 (ja)	2008-09-10
KR20040007503A (ko)	2004-01-24
BR0209151A (pt)	2004-07-13
JP2004529931A (ja)	2004-09-30
AR035935A1 (es)	2004-07-28
DE60210760T2 (de)	2006-11-23

Publication	Publication Date	Title
ATE323531T1 (de)	2006-05-15	Verwendung von nk-1-rezeptorantagonisten gegen benigne prostatahyperplasie
IS7329A (is)	2004-06-21	Flúr setinn sýklóalkanóindól og notkun þeirra semprostaglandín D2 viðtaka mótlyfja
DE60208661D1 (de)	2006-04-06	Diaminothiazole und ihre verwendung als cyclinabhängige kinase inhibitoren
DK1345920T3 (da)	2006-08-14	Hidtil ukendte sulfamider og anvendelse deraf som endothelinreceptorantagonister
DE60037213D1 (de)	2008-01-10	Verwendung von Reinigungsgas
DE60113719D1 (de)	2006-02-09	Chinuclidincarbamat derivate und deren verwendung als m3 antagonisten
DE50212455D1 (de)	2008-08-14	Verwendung von Dimerdiolen
DE60015296D1 (de)	2004-12-02	Indolderivate und ihre verwendung als mcp-1 rezeptor antagonisten
NO20030471D0 (no)	2003-01-30	Karboksamidforbindelser og deres anvendelse som antagonister for en 11CBY-reseptor
DE60114413D1 (de)	2005-12-01	Substituierte 1-aminoalkyl-lactame und deren verwendung als muscarinrezeptor-antagonisten
ATE346043T1 (de)	2006-12-15	Il-8-rezeptorantagonisten
DE02784674T1 (de)	2005-05-04	Quantifizierung von polypeptiden
ATE469875T1 (de)	2010-06-15	Nk1-antagonisten
DE60222693D1 (de)	2007-11-08	Nk1-antagonisten
SI1425280T1 (sl)	2006-12-31	Hetero-biciklicni antagonisti crf
ATE492535T1 (de)	2011-01-15	4-piperidinylalkylamin-derivate, antagonisten von muscarinrezeptoren
ATE356122T1 (de)	2007-03-15	Pyrazolylsubstituierte heterocyclen und ihre verwendung als schädlingsbekämpfungsmittel
DE60224221D1 (de)	2008-01-31	Aminotetralinderivate, antagonisten von muscarinrezeptoren
DE60226419D1 (de)	2008-06-19	Somatostatin-antagonisten
DE60317632D1 (de)	2008-01-03	2-oxazolamine und ihre verwendung als 5-ht2b-rezeptor-antagonisten
DE60217870D1 (de)	2007-03-15	Verwendung von 2- 5-(4-fluorphenyl)-3-pyridylmethylaminomethyl-chroman und seiner physiologisch annehmbaren salze
NO20033223L (no)	2003-07-16	Histamin-reseptor antagonister
ATE370932T1 (de)	2007-09-15	Ccr-3-rezeptorantagonisten vii
DE60317709D1 (de)	2008-01-03	Substituierte 1-piperidin-3-yl-4-piperidin-4-yl-piperazin-derivate und ihre verwendung als neurokinin-antagonisten
DE50201491D1 (de)	2004-12-16	Stossverbindung von Arbeitsplatten

Legal Events

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2007-02-15	UEP	Publication of translation of european patent specification	Ref document number: 1385577 Country of ref document: EP

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