[go: up one dir, main page]

ATE309254T1 - Gewebespezifische fluoreszierende chelate - Google Patents

Gewebespezifische fluoreszierende chelate

Info

Publication number
ATE309254T1
ATE309254T1 AT02773911T AT02773911T ATE309254T1 AT E309254 T1 ATE309254 T1 AT E309254T1 AT 02773911 T AT02773911 T AT 02773911T AT 02773911 T AT02773911 T AT 02773911T AT E309254 T1 ATE309254 T1 AT E309254T1
Authority
AT
Austria
Prior art keywords
tissue
chelates
specific fluorescent
fluorescent chelates
fluorescent
Prior art date
Application number
AT02773911T
Other languages
English (en)
Inventor
Garry E Kiefer
Darryl J Bornhop
Original Assignee
Univ Texas Tech
Dow Global Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas Tech, Dow Global Technologies Inc filed Critical Univ Texas Tech
Application granted granted Critical
Publication of ATE309254T1 publication Critical patent/ATE309254T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02773911T 2001-10-22 2002-10-22 Gewebespezifische fluoreszierende chelate ATE309254T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35568401P 2001-10-22 2001-10-22
PCT/US2002/034242 WO2003035655A1 (en) 2001-10-22 2002-10-22 Tissue specific fluorescent chelates

Publications (1)

Publication Number Publication Date
ATE309254T1 true ATE309254T1 (de) 2005-11-15

Family

ID=23398394

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02773911T ATE309254T1 (de) 2001-10-22 2002-10-22 Gewebespezifische fluoreszierende chelate

Country Status (6)

Country Link
US (1) US6962690B2 (de)
EP (1) EP1438318B1 (de)
JP (1) JP2005507005A (de)
AT (1) ATE309254T1 (de)
DE (1) DE60207288T2 (de)
WO (1) WO2003035655A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005049096A2 (en) * 2003-11-14 2005-06-02 Dow Global Technologies Inc. Protein and polymer conjugates as chelants with enhanced blood retention
DE102004022628A1 (de) * 2004-05-07 2005-12-15 Sensient Imaging Technologies Gmbh FRET-Bioassay
WO2006020779A2 (en) * 2004-08-10 2006-02-23 Dow Global Technologies Inc. Targeting chelants and chelates
CA2578030A1 (en) * 2004-08-26 2006-03-09 Mallinckrodt Inc. Luminescent metal complexes for monitoring renal function
WO2006120444A1 (en) * 2005-05-11 2006-11-16 University Of Durham Responsive luminescent lanthanide complexes
US8193174B2 (en) 2005-05-11 2012-06-05 University Of Durham Responsive luminescent lanthanide complexes
GB0613823D0 (en) 2006-07-12 2006-08-23 Univ Durham Assay
US7996068B2 (en) * 2007-03-14 2011-08-09 The Board Of Trustees Of The Leland Stanford Junior University Surgical method and apparatus for identification of fluorescence
US8445217B2 (en) 2007-09-20 2013-05-21 Vanderbilt University Free solution measurement of molecular interactions by backscattering interferometry
US20100036260A1 (en) * 2008-08-07 2010-02-11 Remicalm Llc Oral cancer screening device
US9638632B2 (en) 2010-06-11 2017-05-02 Vanderbilt University Multiplexed interferometric detection system and method
US9562853B2 (en) 2011-02-22 2017-02-07 Vanderbilt University Nonaqueous backscattering interferometric methods
US9273949B2 (en) 2012-05-11 2016-03-01 Vanderbilt University Backscattering interferometric methods
EP3247988A4 (de) 2015-01-23 2018-12-19 Vanderbilt University Robustes interferometer und verfahren zur verwendung davon
US10627396B2 (en) 2016-01-29 2020-04-21 Vanderbilt University Free-solution response function interferometry

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8502573D0 (sv) 1985-05-23 1985-05-23 Jouko Kanakre Fluorescent lanthanide chelates useful as labels of physiologically active materials
US4976950A (en) 1988-12-19 1990-12-11 The Dow Chemical Company Bone marrow suppressing agents
US5312922A (en) 1992-04-06 1994-05-17 Nordion International Inc. Europium and terbium chelators for time-resolved fluorometric assays
US5714604A (en) 1993-05-06 1998-02-03 The Dow Chemical Company Process for the preparation of azamacrocyclic or acyclic aminophosphonate ester derivatives
US5462725A (en) * 1993-05-06 1995-10-31 The Dow Chemical Company 2-pyridylmethylenepolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
EP0898574B1 (de) 1996-04-19 2003-11-12 Dow Global Technologies Inc. Fluoreszierende chelate als gewebespezifische bildgebende mittel
WO2003020701A2 (en) * 2001-09-04 2003-03-13 Texas Tech University Multi-use multimodal imaging chelates

Also Published As

Publication number Publication date
JP2005507005A (ja) 2005-03-10
DE60207288T2 (de) 2006-05-18
WO2003035655A1 (en) 2003-05-01
EP1438318A1 (de) 2004-07-21
EP1438318B1 (de) 2005-11-09
US20030099598A1 (en) 2003-05-29
DE60207288D1 (de) 2005-12-15
US6962690B2 (en) 2005-11-08

Similar Documents

Publication Publication Date Title
ATE254129T1 (de) Fluoreszierende chelate als gewebespezifische bildgebende mittel
ATE309254T1 (de) Gewebespezifische fluoreszierende chelate
AU2002339865A8 (en) Methods and compositions useful for diagnosis, staging, and treatment of cancers and tumors
IL180896A0 (en) Method of tumour imaging
AU3983201A (en) Compositions and methods for the early diagnosis of ovarian cancer
AU3491001A (en) Compositions and methods for the early diagnosis of ovarian cancer
HK1148783A1 (zh) 用於乳房腺的預後的基因表達標記
ATE377381T1 (de) Diffusionsbildgebung von gewebe
WO2002080754A3 (en) Methods for using annexin for detecting cell death in vivo and treating associated conditions
HUP0200763A2 (en) Compositions for the treatment and diagnosis of breast cancer and methods for their use
PL365244A1 (en) Compositions and methods for the therapy and diagnosis of breast cancer
NO20015814D0 (no) Metallkompleksforbindelser
AU2002246519A8 (en) Compositions and methods for the therapy and diagnosis of colon cancer
GB0211247D0 (en) Compositions and methods for treating or preventing convulsions or seizures
AU2002339439A1 (en) Use of heparin-binding domain of fibronectin for diagnosis and treatment of cancer
AU2003237792A8 (en) Compositions and methods for the diagnosis and treatment of tumor
DE60221115D1 (de) Zusammensetzungen und verfahren zur verwendung von fibronektin-fragmenten bei krebsdiagnose
EP1349485A4 (de) Zusammensetzungen und verfahren zur therapie und diagnose des ovarialkarzinoms
IL155135A (en) Apparatus for prostate cancer diagnosis
PL350863A1 (en) Compositions and methods for the treatment and diagnosis of breast cancer
ZA200108256B (en) Compositions and methods for the treatment and diagnosis of breast cancer.
WO2005115105A3 (en) Self-immolative magnetic resonance imaging contrast agents sensitive to beta-glucuronidase
ZA200604365B (en) Compositions and methods for the diagnosis and treatment of tumor
IL145589A0 (en) In vivo stain compounds and methods of use to identify dysplastic tissue
AU2002332606A8 (en) Compositions and methods for the therapy and diagnosis of colon cancer

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties