ATE299936T1 - Fas antigen-derivate - Google Patents
Fas antigen-derivateInfo
- Publication number
- ATE299936T1 ATE299936T1 AT97918354T AT97918354T ATE299936T1 AT E299936 T1 ATE299936 T1 AT E299936T1 AT 97918354 T AT97918354 T AT 97918354T AT 97918354 T AT97918354 T AT 97918354T AT E299936 T1 ATE299936 T1 AT E299936T1
- Authority
- AT
- Austria
- Prior art keywords
- fas antigen
- amino acid
- derivative
- antigen derivative
- fas
- Prior art date
Links
- 108010052621 fas Receptor Proteins 0.000 title abstract 8
- 102000018823 fas Receptor Human genes 0.000 title abstract 8
- 102000053602 DNA Human genes 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 125000000729 N-terminal amino-acid group Chemical group 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13576096 | 1996-05-02 | ||
PCT/JP1997/001502 WO1997042319A1 (fr) | 1996-05-02 | 1997-05-01 | NOUVEAUX DERIVES DE L'ANTIGENE Fas |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE299936T1 true ATE299936T1 (de) | 2005-08-15 |
Family
ID=15159230
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97918354T ATE299936T1 (de) | 1996-05-02 | 1997-05-01 | Fas antigen-derivate |
Country Status (7)
Country | Link |
---|---|
US (2) | US6306395B1 (de) |
EP (1) | EP0965637B1 (de) |
AT (1) | ATE299936T1 (de) |
AU (1) | AU2650597A (de) |
CA (1) | CA2253494A1 (de) |
DE (1) | DE69733773T2 (de) |
WO (1) | WO1997042319A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6905684B1 (en) | 1997-11-10 | 2005-06-14 | Mochida Pharmaceutical Co., Ltd. | Preventives and remedies for diffuse lung diseases |
ATE361119T1 (de) * | 1998-05-14 | 2007-05-15 | Mochida Pharm Co Ltd | Prävention und therapie von leberzirrhosen |
EP1082967B1 (de) | 1998-05-29 | 2006-07-19 | Mochida Pharmaceutical Co., Ltd. | Prophylaxe und Behandlung von autoimmunen Entmyelinisierungserkrankungen durch Fas-antagonisten |
US6942981B1 (en) * | 1999-05-14 | 2005-09-13 | Arbor Vita Corporation | Method of determining interactions with PDZ-domain polypeptides |
US20050037969A1 (en) * | 1999-05-14 | 2005-02-17 | Arbor Vita Corporation | Molecular interactions in hematopoietic cells |
ATE324444T1 (de) * | 1999-06-07 | 2006-05-15 | Immunex Corp | Tek-antagonisten |
US7087411B2 (en) * | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
EP1418935A1 (de) * | 2001-08-01 | 2004-05-19 | Genset S.A. | Genobix agonisten und antagonisten zur verwendung bei der behandlung von stoffwechselkrankheiten |
GB2381122B (en) * | 2001-10-16 | 2006-04-05 | Zetex Plc | Termination structure for a semiconductor device |
US7910694B2 (en) * | 2002-09-19 | 2011-03-22 | Cornell Research Foundation, Inc. | Homing peptides to receptors of heart vasculature |
EP1606319A2 (de) | 2003-03-26 | 2005-12-21 | Apogenix GmbH | Behandlung viraler infektionen |
ES2420582T3 (es) | 2006-12-28 | 2013-08-26 | Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts | La neutralización de la actividad de CD95 bloquea la invasión de células de glioblastoma in vivo |
US20090196868A1 (en) * | 2007-09-06 | 2009-08-06 | Apogenix Gmbh | Methods and compositions for preventing radiation-induced pneumonitis |
EP3144320B9 (de) * | 2011-04-13 | 2018-08-22 | Bristol-Myers Squibb Company | Fc-fusionsproteine mit neuartigen linkern oder anordnungen |
JP6231562B2 (ja) * | 2012-07-18 | 2017-11-15 | アポジェニックス アーゲー | CD95−Fcアイソフォームの混合物を含む組成物 |
RU2652348C2 (ru) | 2012-07-18 | 2018-04-25 | Аподжиникс Аг | Ингибиторы сигнального пути cd95 для лечения мдс |
EP3076179A1 (de) | 2015-03-30 | 2016-10-05 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Diagnose und behandlung von minderwertigen glioma |
CN114269370A (zh) | 2019-03-29 | 2022-04-01 | 迈斯特治疗公司 | 离体产生t细胞治疗剂的方法以及相关的组合物和方法 |
JP2023504042A (ja) | 2019-11-27 | 2023-02-01 | ミスト セラピューティクス リミテッド ライアビリティ カンパニー | 調節物質を使用した腫瘍反応性t細胞組成物の生成方法 |
MX2022010517A (es) | 2020-02-27 | 2022-11-14 | Myst Therapeutics Llc | Metodos para la expansion y enriquecimiento ex vivo de celulas t reactivas a tumor y composiciones relacionadas de las mismas. |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5116964A (en) * | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
CA2067031C (en) * | 1991-04-26 | 2003-02-18 | Shigekazu Nagata | Dna coding for human cell surface antigen |
US5770197A (en) | 1991-06-27 | 1998-06-23 | Bristol-Myers Squibb Company | Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules |
JPH08127594A (ja) | 1993-11-10 | 1996-05-21 | Mochida Pharmaceut Co Ltd | Fas抗原に結合する新規蛋白質およびそれをコードするDNA |
JPH07289266A (ja) | 1994-04-21 | 1995-11-07 | Mochida Pharmaceut Co Ltd | ヒトFas抗原バリアント及びそれをコードする新規DNA |
-
1997
- 1997-05-01 CA CA002253494A patent/CA2253494A1/en not_active Abandoned
- 1997-05-01 AT AT97918354T patent/ATE299936T1/de not_active IP Right Cessation
- 1997-05-01 DE DE69733773T patent/DE69733773T2/de not_active Expired - Lifetime
- 1997-05-01 US US09/180,100 patent/US6306395B1/en not_active Expired - Fee Related
- 1997-05-01 WO PCT/JP1997/001502 patent/WO1997042319A1/ja active IP Right Grant
- 1997-05-01 AU AU26505/97A patent/AU2650597A/en not_active Abandoned
- 1997-05-01 EP EP97918354A patent/EP0965637B1/de not_active Expired - Lifetime
-
2001
- 2001-09-12 US US09/949,713 patent/US6953847B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1997042319A1 (fr) | 1997-11-13 |
CA2253494A1 (en) | 1997-11-13 |
EP0965637A4 (de) | 2002-09-25 |
DE69733773T2 (de) | 2006-04-20 |
EP0965637B1 (de) | 2005-07-20 |
US6306395B1 (en) | 2001-10-23 |
EP0965637A1 (de) | 1999-12-22 |
DE69733773D1 (de) | 2005-08-25 |
US6953847B2 (en) | 2005-10-11 |
US20020044944A1 (en) | 2002-04-18 |
AU2650597A (en) | 1997-11-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |