ATE272213T1 - Vorrichtungen und verfahren zur durchführung miniaturisierter homogener tests - Google Patents
Vorrichtungen und verfahren zur durchführung miniaturisierter homogener testsInfo
- Publication number
- ATE272213T1 ATE272213T1 AT00939944T AT00939944T ATE272213T1 AT E272213 T1 ATE272213 T1 AT E272213T1 AT 00939944 T AT00939944 T AT 00939944T AT 00939944 T AT00939944 T AT 00939944T AT E272213 T1 ATE272213 T1 AT E272213T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- platform
- devices
- microsynthetic
- miniaturized
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/20—Jet mixers, i.e. mixers using high-speed fluid streams
- B01F25/23—Mixing by intersecting jets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/71725—Feed mechanisms characterised by the means for feeding the components to the mixer using centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00421—Means for dispensing and evacuation of reagents using centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
- B01J2219/00488—Means for mixing reactants or products in the reaction vessels by rotation of the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
- B01J2219/00536—Sheets in the shape of disks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00704—Processes involving means for analysing and characterising the products integrated with the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0605—Metering of fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
- B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00495—Centrifuges
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/111666—Utilizing a centrifuge or compartmented rotor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14010599P | 1999-06-18 | 1999-06-18 | |
PCT/US2000/016653 WO2000079285A2 (en) | 1999-06-18 | 2000-06-16 | Devices and methods for the performance of miniaturized homogeneous assays |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE272213T1 true ATE272213T1 (de) | 2004-08-15 |
Family
ID=22489780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00939944T ATE272213T1 (de) | 1999-06-18 | 2000-06-16 | Vorrichtungen und verfahren zur durchführung miniaturisierter homogener tests |
Country Status (7)
Country | Link |
---|---|
US (2) | US6582662B1 (de) |
EP (1) | EP1230544B1 (de) |
JP (1) | JP2004529312A (de) |
AT (1) | ATE272213T1 (de) |
AU (1) | AU5494900A (de) |
DE (1) | DE60012562D1 (de) |
WO (1) | WO2000079285A2 (de) |
Families Citing this family (111)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2790684B1 (fr) * | 1999-03-09 | 2001-05-11 | Biomerieux Sa | Appareil permettant en son sein le transfert de liquides par capillarite |
ATE272213T1 (de) * | 1999-06-18 | 2004-08-15 | Gamera Bioscience Corp | Vorrichtungen und verfahren zur durchführung miniaturisierter homogener tests |
US20020151078A1 (en) * | 2000-05-15 | 2002-10-17 | Kellogg Gregory J. | Microfluidics devices and methods for high throughput screening |
US6734401B2 (en) | 2000-06-28 | 2004-05-11 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
US6720187B2 (en) * | 2000-06-28 | 2004-04-13 | 3M Innovative Properties Company | Multi-format sample processing devices |
US6627159B1 (en) | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
EP1301268A2 (de) * | 2000-07-03 | 2003-04-16 | Xeotron Corporation | Verfahren und vorrichtungen zur durchführung chemischer reaktionen unter anwendung von photochemisch erzeugten reagenzien |
US7087203B2 (en) * | 2000-11-17 | 2006-08-08 | Nagaoka & Co., Ltd. | Methods and apparatus for blood typing with optical bio-disc |
US7026131B2 (en) * | 2000-11-17 | 2006-04-11 | Nagaoka & Co., Ltd. | Methods and apparatus for blood typing with optical bio-discs |
US7429354B2 (en) | 2001-03-19 | 2008-09-30 | Gyros Patent Ab | Structural units that define fluidic functions |
US20030118804A1 (en) * | 2001-05-02 | 2003-06-26 | 3M Innovative Properties Company | Sample processing device with resealable process chamber |
US20020168292A1 (en) * | 2001-05-14 | 2002-11-14 | Whisenhunt Donald Wayne | Systems and methods for the high throughput preparation and analysis of chemical reactions |
US7433744B2 (en) * | 2001-06-21 | 2008-10-07 | Robert A Bell | Method and apparatus for spatially coordinating, storing and manipulating computer aided design drawings |
US6919058B2 (en) | 2001-08-28 | 2005-07-19 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
SE0104077D0 (sv) * | 2001-10-21 | 2001-12-05 | Gyros Ab | A method and instrumentation for micro dispensation of droplets |
AT500669B1 (de) * | 2001-09-24 | 2007-02-15 | Oesterr Forsch Seibersdorf | Fester träger zur immobilisierung von biomolekülen |
US7244393B2 (en) | 2001-12-21 | 2007-07-17 | Kimberly-Clark Worldwide, Inc. | Diagnostic device and system |
US6889468B2 (en) | 2001-12-28 | 2005-05-10 | 3M Innovative Properties Company | Modular systems and methods for using sample processing devices |
CN1625779A (zh) * | 2002-01-28 | 2005-06-08 | 长冈实业株式会社 | 逻辑触发光生物盘的方法和设备 |
EP1470424A2 (de) | 2002-01-31 | 2004-10-27 | Burstein Technologies, Inc. | Verfahren zum auslösen mittels platterillen und entsprechende optische analyse-platten |
US20040241381A1 (en) * | 2002-01-31 | 2004-12-02 | Chen Yihfar | Microfluidic structures with circumferential grooves for bonding adhesives and related optical analysis discs |
US7459127B2 (en) * | 2002-02-26 | 2008-12-02 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces |
JP4194787B2 (ja) * | 2002-03-14 | 2008-12-10 | パナソニック株式会社 | 分析装置とそれに使用する分析用ディスク |
JP4338529B2 (ja) | 2002-04-08 | 2009-10-07 | ユロス・パテント・アクチボラゲット | ホーミングプロセス |
US7005265B1 (en) | 2002-06-20 | 2006-02-28 | Wenhong Fan | Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays |
US7083974B2 (en) | 2002-07-12 | 2006-08-01 | Applera Corporation | Rotatable sample disk and method of loading a sample disk |
EP1391237B1 (de) * | 2002-08-01 | 2011-09-21 | Tosoh Corporation | Vorrichtung mit feinen Kanälen, miniaturisierte chemische Anlage zur Herstellung feiner Partikel und Vorrichtung zu dessen Verwendung |
US7094354B2 (en) * | 2002-12-19 | 2006-08-22 | Bayer Healthcare Llc | Method and apparatus for separation of particles in a microfluidic device |
US7125711B2 (en) * | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
EP1578533A2 (de) * | 2002-12-24 | 2005-09-28 | Tecan Trading AG | Mikrofluidvorrichtungen und verfahren zum verdünnen von proben und reagenzien |
US7332129B2 (en) | 2003-01-09 | 2008-02-19 | 3M Innovative Properties Company | Sample processing device having process chambers with bypass slots |
JP4519124B2 (ja) | 2003-01-30 | 2010-08-04 | ユィロス・パテント・アクチボラグ | 微小流動性デバイスの内部の壁 |
SE0300822D0 (sv) | 2003-03-23 | 2003-03-23 | Gyros Ab | A collection of Micro Scale Devices |
SE0300823D0 (sv) | 2003-03-23 | 2003-03-23 | Gyros Ab | Preloaded Microscale Devices |
JP2004309145A (ja) * | 2003-04-02 | 2004-11-04 | Hitachi High-Technologies Corp | 化学分析装置及び化学分析用構造体 |
US20040241049A1 (en) * | 2003-04-04 | 2004-12-02 | Carvalho Bruce L. | Elastomeric tools for the fabrication of elastomeric devices and uses thereof |
US7435381B2 (en) * | 2003-05-29 | 2008-10-14 | Siemens Healthcare Diagnostics Inc. | Packaging of microfluidic devices |
US20040265171A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method for uniform application of fluid into a reactive reagent area |
US7347617B2 (en) * | 2003-08-19 | 2008-03-25 | Siemens Healthcare Diagnostics Inc. | Mixing in microfluidic devices |
US20050130177A1 (en) | 2003-12-12 | 2005-06-16 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US7837947B2 (en) * | 2003-12-12 | 2010-11-23 | 3M Innovative Properties Company | Sample mixing on a microfluidic device |
US7322254B2 (en) * | 2003-12-12 | 2008-01-29 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US20050142570A1 (en) * | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and sedimenting reagent |
US7939249B2 (en) | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
US20050142571A1 (en) * | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using solid phase material |
JP4646809B2 (ja) * | 2003-12-26 | 2011-03-09 | パナソニック株式会社 | 生体サンプル判別装置、生体サンプル判別方法、及び生体サンプル判別用プレート |
US8592219B2 (en) * | 2005-01-17 | 2013-11-26 | Gyros Patent Ab | Protecting agent |
SE0400181D0 (sv) | 2004-01-29 | 2004-01-29 | Gyros Ab | Segmented porous and preloaded microscale devices |
JP2005257337A (ja) * | 2004-03-09 | 2005-09-22 | Brother Ind Ltd | 検査対象受体、検査装置、及び検査方法 |
US20050227350A1 (en) * | 2004-04-13 | 2005-10-13 | Agency For Science, Technology And Research | Device and method for studying cell migration and deformation |
US7758814B2 (en) * | 2004-06-05 | 2010-07-20 | Freeslate, Inc. | Microfluidic fluid distribution manifold for use with multi-channel reactor systems |
WO2006004939A2 (en) * | 2004-06-29 | 2006-01-12 | University Of Cincinnati | Polymorphisms and haplotypes of the alpha 2c adrenergic receptor gene |
WO2006009505A1 (en) * | 2004-07-16 | 2006-01-26 | Gyros Patent Ab | Grading of immune responses |
US8097225B2 (en) * | 2004-07-28 | 2012-01-17 | Honeywell International Inc. | Microfluidic cartridge with reservoirs for increased shelf life of installed reagents |
DE102004046396A1 (de) | 2004-09-24 | 2006-04-13 | Land Baden-Württemberg, vertreten durch das Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg, vertreten durch den Minister | Partikelsedimentationsvorrichtung und Verfahren zum Durchführen einer Partikelsedimentation |
US7832429B2 (en) * | 2004-10-13 | 2010-11-16 | Rheonix, Inc. | Microfluidic pump and valve structures and fabrication methods |
US7608160B2 (en) * | 2004-10-13 | 2009-10-27 | Rheonix, Inc. | Laminated microfluidic structures and method for making |
JP5006800B2 (ja) | 2005-01-17 | 2012-08-22 | ユィロス・パテント・アクチボラグ | 二つの親和性反応物を用いて、少なくとも二価のアナライトを検出する方法 |
JP4693657B2 (ja) * | 2005-03-29 | 2011-06-01 | シチズンホールディングス株式会社 | バイオセンサ |
JP4689665B2 (ja) * | 2005-04-04 | 2011-05-25 | パナソニック株式会社 | 液体均一化装置およびそれを用いた分析装置 |
WO2006108559A2 (de) * | 2005-04-09 | 2006-10-19 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung und verfahren zur untersuchung einer probenflüssigkeit |
JP4927817B2 (ja) * | 2005-04-14 | 2012-05-09 | ギロス・パテント・エービー | 多数の弁を備えるマイクロ流体装置 |
US7947235B2 (en) | 2005-04-14 | 2011-05-24 | Gyros Ab | Microfluidic device with finger valves |
EP1874677B1 (de) * | 2005-04-14 | 2013-03-20 | Gyros Patent Ab | Mikrofluidische Vorrichtung mit Mäander |
EP1874674B1 (de) | 2005-04-14 | 2013-06-05 | Gyros Patent Ab | Flüssigkeitspfropfen |
US7754474B2 (en) | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
USD564667S1 (en) | 2005-07-05 | 2008-03-18 | 3M Innovative Properties Company | Rotatable sample processing disk |
US7323660B2 (en) * | 2005-07-05 | 2008-01-29 | 3M Innovative Properties Company | Modular sample processing apparatus kits and modules |
US7763210B2 (en) | 2005-07-05 | 2010-07-27 | 3M Innovative Properties Company | Compliant microfluidic sample processing disks |
DE102005031920B4 (de) * | 2005-07-07 | 2007-12-20 | Isotopen Technologien München AG | Vorrichtung und Verfahren zur Herstellung einer geringen Menge einer radioaktiven Substanzverbindung |
US7731910B2 (en) * | 2005-08-05 | 2010-06-08 | Hewlett-Packard Development Company, L.P. | Microfluidic mixing assembly |
EP2237037A1 (de) | 2005-12-12 | 2010-10-06 | Gyros Patent Ab | Mikrofluid-Vorrichtung und deren Verwendung |
TWI272464B (en) * | 2006-03-01 | 2007-02-01 | Instr Technology Res Ct Nat Ap | Fluid order controlling apparatus and method |
US7651869B2 (en) * | 2006-03-14 | 2010-01-26 | Research International, Inc. | Optical assay apparatus and methods |
TW200840641A (en) * | 2007-04-03 | 2008-10-16 | Univ Nat Taiwan | Disk-shaped concentration regulation flow channel structure |
JPWO2007116909A1 (ja) * | 2006-04-04 | 2009-08-20 | パナソニック株式会社 | 試料液分析用パネル |
US20080243309A2 (en) * | 2006-05-08 | 2008-10-02 | Auburn University | Systems for and methods of characterizing reactions |
US7384798B2 (en) * | 2006-10-31 | 2008-06-10 | Hewlett-Packard Development Company, L.P. | Method of detecting analytes in a microfluidic sample and a system for performing the same |
KR101228112B1 (ko) * | 2006-12-06 | 2013-01-31 | 삼성전자주식회사 | 원심력과 펌프를 이용해 유체의 이동을 제어하는 미세유동장치 및 이를 포함하는 미세유동 시스템 |
KR101596189B1 (ko) | 2006-12-22 | 2016-02-19 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 미세유체 시스템을 위한 열 전달 방법 및 구조체 |
US20080152546A1 (en) * | 2006-12-22 | 2008-06-26 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
KR101305976B1 (ko) * | 2007-02-12 | 2013-09-12 | 삼성전자주식회사 | 연속희석을 위한 원심력 기반의 미세유동장치 및 이를포함하는 미세유동시스템 |
KR101278154B1 (ko) * | 2007-04-16 | 2013-06-27 | 삼성전자주식회사 | 원심력 기반의 미세유동 장치, 이를 구비한 미세유동시스템 및, 상기 미세유동 장치의 홈 위치 결정 방법 |
KR20080107212A (ko) | 2007-06-05 | 2008-12-10 | 삼성전자주식회사 | 유체 컨테이너를 구비한 미세유동 장치 |
EP2017006A1 (de) * | 2007-07-20 | 2009-01-21 | Koninklijke Philips Electronics N.V. | Mikrofluidische Verfahren und Systeme zur Verwendung bei der Analytdetektion |
US20110097814A1 (en) * | 2007-11-20 | 2011-04-28 | Bommarito G Marco | Detection devices and methods |
US20090247902A1 (en) * | 2008-03-27 | 2009-10-01 | Reichert Julie A | Method and apparatus for transporting a patient sample between a sterile and non-sterile area |
US20110092049A1 (en) * | 2008-05-23 | 2011-04-21 | Zhenfang Chen | Method and apparatus for substrate bonding |
FI120818B (fi) * | 2008-05-28 | 2010-03-31 | Thermo Fisher Scientific Oy | Reaktioastia ja menetelmä sen käsittelemiseksi |
US8221299B2 (en) * | 2008-06-17 | 2012-07-17 | Bio-Rad Laboratories, Inc. | Centrifugal force-based system for detection/treatment of membrane-encased structures |
CN102105800B (zh) * | 2008-07-22 | 2014-05-28 | 爱科来株式会社 | 微型模件以及分析装置 |
KR101099495B1 (ko) * | 2008-10-14 | 2011-12-28 | 삼성전자주식회사 | 원심력 기반의 미세유동장치, 이의 제조 방법 및 이를 이용한 시료분석방법 |
US8834792B2 (en) | 2009-11-13 | 2014-09-16 | 3M Innovative Properties Company | Systems for processing sample processing devices |
USD638550S1 (en) | 2009-11-13 | 2011-05-24 | 3M Innovative Properties Company | Sample processing disk cover |
USD667561S1 (en) | 2009-11-13 | 2012-09-18 | 3M Innovative Properties Company | Sample processing disk cover |
USD638951S1 (en) | 2009-11-13 | 2011-05-31 | 3M Innovative Properties Company | Sample processing disk cover |
US9168523B2 (en) | 2011-05-18 | 2015-10-27 | 3M Innovative Properties Company | Systems and methods for detecting the presence of a selected volume of material in a sample processing device |
BR112013027990B1 (pt) | 2011-05-18 | 2020-11-03 | Diasorin S.P.A. | estrutura de válvulas em um dispositivo de processamento de amostras e método para funcionamento de válvulas em um dispositivo de processamento de amostras |
EP2709761B1 (de) | 2011-05-18 | 2019-08-14 | DiaSorin S.p.A. | Vorrichtung and verfharen zum dosieren auf einem probenverarbeitungsvorrichtung |
USD672467S1 (en) | 2011-05-18 | 2012-12-11 | 3M Innovative Properties Company | Rotatable sample processing disk |
KR101329649B1 (ko) | 2011-10-26 | 2013-11-14 | 한국기초과학지원연구원 | 나선형 미세유로를 이용한 단백질 결정화 조건 고속 스크리닝 장치 및 방법 |
KR20130086743A (ko) * | 2012-01-26 | 2013-08-05 | 삼성전자주식회사 | 미세유동장치 및 그 제어방법 |
JP6087272B2 (ja) * | 2013-12-20 | 2017-03-01 | 信越ポリマー株式会社 | 分析基板 |
US9757728B2 (en) * | 2016-01-26 | 2017-09-12 | Lidong Qin | Microfluidic aliquoting for single-cell isolation |
US11161107B2 (en) * | 2016-05-25 | 2021-11-02 | Integrated Micro-Chromatography Systems, Inc. | Dispersive pipette extraction system for purification of large biomolecules |
US11439970B2 (en) * | 2018-05-22 | 2022-09-13 | Microsoft Technology Licensing, Llc | DNA manufacturing, storage, and access system |
KR102401909B1 (ko) | 2018-08-30 | 2022-05-24 | 주식회사 엘지화학 | 반응 최적화를 위한 고속 스크리닝 분석 시스템 |
CN111778137B (zh) * | 2020-06-29 | 2023-01-31 | 上海思路迪生物医学科技有限公司 | 一种三自由度文库制备卡盒及方法 |
KR20230068430A (ko) * | 2020-09-17 | 2023-05-17 | 시트로겐 인코포레이티드 | 미생물의 신속한 고처리량 식별을 위한 미세유체 디바이스 및 방법 |
CN113234571B (zh) * | 2021-04-29 | 2023-08-25 | 杭州霆科生物科技有限公司 | 一种高通量酶筛选芯片 |
WO2023059894A1 (en) * | 2021-10-08 | 2023-04-13 | Baebies, Inc. | Digital microfluidics multi-dynamic range parallel biochemical assays |
Family Cites Families (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3528449A (en) * | 1968-02-27 | 1970-09-15 | Trw Inc | Fluid flow control apparatus |
US3679367A (en) * | 1970-09-14 | 1972-07-25 | Technicon Instr | Apparatus for determining the pack volume of particulates in liquid mixtures |
US3713062A (en) * | 1970-12-29 | 1973-01-23 | Texas Instruments Inc | Snap disc thermal sequencer |
US3952116A (en) * | 1974-09-17 | 1976-04-20 | Texas Instruments Incorporated | Process for forming electrical resistance heaters |
US4030834A (en) * | 1976-04-08 | 1977-06-21 | The United States Of America As Represented By The United States Energy Research And Development Administration | Dynamic multistation photometer |
US4258740A (en) * | 1977-05-16 | 1981-03-31 | Packard Instrument Company, Inc. | Fluid flow control device |
FR2400700A1 (fr) * | 1977-08-18 | 1979-03-16 | Guigan Jean | Dispositif de conditionnement d'un echantillon de liquide en vue de son analyse |
FR2409514A1 (fr) * | 1977-11-17 | 1979-06-15 | Bretaudiere Jean Pierre | Perfectionnement aux appareils d'analyse par centrifugation |
US4381291A (en) * | 1979-02-23 | 1983-04-26 | Ab Fortia | Measurement of free ligands |
DE3044385A1 (de) * | 1980-11-25 | 1982-06-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur durchfuehrung analytischer bestimmungen und hierfuer geeignetes rotoreinsatzelement |
US4729862A (en) * | 1981-04-24 | 1988-03-08 | Allied-Signal Inc. | Nylon composition for use in rotational molding |
US5496520A (en) * | 1982-01-08 | 1996-03-05 | Kelton; Arden A. | Rotary fluid manipulator |
DE3314961A1 (de) * | 1983-04-25 | 1984-10-25 | Boehringer Mannheim Gmbh, 6800 Mannheim | Analysegeraet zur photometrischen bestimmung eines parameters einer fluessigkeit |
GB8317124D0 (en) * | 1983-06-23 | 1983-07-27 | Ekins R P | Free ligand assay |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4612959A (en) * | 1985-05-07 | 1986-09-23 | Mobil Oil Corporation | Valveless shut-off and transfer device |
US4722853A (en) * | 1985-08-12 | 1988-02-02 | Raychem Corporation | Method of printing a polymer thick film ink |
US5171695A (en) * | 1986-08-06 | 1992-12-15 | Multilyte Limited | Determination of analyte concentration using two labelling markers |
US4935346A (en) * | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
US4872821A (en) * | 1987-03-23 | 1989-10-10 | Gold Medal Products Co. | Cotton candy machine |
US4940527A (en) * | 1987-06-01 | 1990-07-10 | Abbott Laboratories | Two-part test cartridge for centrifuge |
US5173262A (en) * | 1987-07-17 | 1992-12-22 | Martin Marietta Energy Systems, Inc. | Rotor assembly and method for automatically processing liquids |
US5242803A (en) * | 1987-07-17 | 1993-09-07 | Martin Marietta Energy Systems, Inc. | Rotor assembly and assay method |
US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
US5252294A (en) * | 1988-06-01 | 1993-10-12 | Messerschmitt-Bolkow-Blohm Gmbh | Micromechanical structure |
US5160702A (en) * | 1989-01-17 | 1992-11-03 | Molecular Devices Corporation | Analyzer with improved rotor structure |
US5171533A (en) * | 1989-07-31 | 1992-12-15 | Fine Richard A | Biological assay cassette and method for making same |
US5006749A (en) * | 1989-10-03 | 1991-04-09 | Regents Of The University Of California | Method and apparatus for using ultrasonic energy for moving microminiature elements |
US5061381A (en) * | 1990-06-04 | 1991-10-29 | Abaxis, Inc. | Apparatus and method for separating cells from biological fluids |
US5242606A (en) * | 1990-06-04 | 1993-09-07 | Abaxis, Incorporated | Sample metering port for analytical rotor having overflow chamber |
US5122284A (en) * | 1990-06-04 | 1992-06-16 | Abaxis, Inc. | Apparatus and method for optically analyzing biological fluids |
US5173193A (en) * | 1991-04-01 | 1992-12-22 | Schembri Carol T | Centrifugal rotor having flow partition |
US5186844A (en) * | 1991-04-01 | 1993-02-16 | Abaxis, Inc. | Apparatus and method for continuous centrifugal blood cell separation |
US5210664A (en) | 1991-05-28 | 1993-05-11 | Iomega Corporation | Low profile tape drive for driving a mini-data cartridge |
US5413732A (en) * | 1991-08-19 | 1995-05-09 | Abaxis, Inc. | Reagent compositions for analytical testing |
DE4140554A1 (de) * | 1991-12-09 | 1993-06-17 | Biedermann Motech Gmbh | Knieorthese |
US5304348A (en) * | 1992-02-11 | 1994-04-19 | Abaxis, Inc. | Reagent container for analytical rotor |
WO1993019827A1 (en) * | 1992-04-02 | 1993-10-14 | Abaxis, Inc. | Analytical rotor with dye mixing chamber |
US5275016A (en) * | 1992-04-24 | 1994-01-04 | Abaxis, Inc. | Cryogenic apparatus |
DE69303483T2 (de) | 1992-05-01 | 1997-02-06 | Univ Pennsylvania | Mikrohergestellte Vorrichtungen zum Handhaben von Sperma |
US5304487A (en) | 1992-05-01 | 1994-04-19 | Trustees Of The University Of Pennsylvania | Fluid handling in mesoscale analytical devices |
WO1994017146A1 (en) * | 1993-01-29 | 1994-08-04 | Pentel Kabushiki Kaisha | Water color ink having metallic luster for ball-point pens |
US5478750A (en) * | 1993-03-31 | 1995-12-26 | Abaxis, Inc. | Methods for photometric analysis |
EP0702728B1 (de) | 1993-06-09 | 1998-04-15 | Gamera Bioscience Corporation | Magnetische zyklusreaktionen |
US5432009A (en) * | 1993-06-17 | 1995-07-11 | Sekisui Kagaku Kogyo Kabushiki Kaisha | Film for first-aid sticking plaster |
US5368704A (en) * | 1993-08-06 | 1994-11-29 | Teknekron Corporation | Micro-electrochemical valves and method |
US5591643A (en) * | 1993-09-01 | 1997-01-07 | Abaxis, Inc. | Simplified inlet channels |
US5409665A (en) * | 1993-09-01 | 1995-04-25 | Abaxis, Inc. | Simultaneous cuvette filling with means to isolate cuvettes |
US5431303A (en) * | 1993-09-30 | 1995-07-11 | Miskell; David L. | Two-part aerosol dispenser employing fusible plug |
US5403415A (en) * | 1993-11-17 | 1995-04-04 | Abaxis, Inc. | Method and device for ultrasonic welding |
US5413009A (en) * | 1994-03-16 | 1995-05-09 | Fragnito; Frank | Variable speed transmission assembly |
US5590052A (en) * | 1994-04-14 | 1996-12-31 | Abaxis, Inc. | Error checking in blood analyzer |
US5639428A (en) * | 1994-07-19 | 1997-06-17 | Becton Dickinson And Company | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay |
US5876187A (en) * | 1995-03-09 | 1999-03-02 | University Of Washington | Micropumps with fixed valves |
US5622819A (en) * | 1995-03-28 | 1997-04-22 | Kinetic Biosystems, Inc. | Centrifugal fermentation process |
US6143247A (en) * | 1996-12-20 | 2000-11-07 | Gamera Bioscience Inc. | Affinity binding-based system for detecting particulates in a fluid |
JP2002503331A (ja) | 1995-12-05 | 2002-01-29 | ガメラ バイオサイエンス コーポレイション | 機内に搭載された情報科学を備えた超微量液体素子工学システムにおいて液体移動を推進するために求心性加速を使用するための装置及び方法 |
US20010055812A1 (en) | 1995-12-05 | 2001-12-27 | Alec Mian | Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
US6074827A (en) * | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
US6632399B1 (en) * | 1998-05-22 | 2003-10-14 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays |
AU7591998A (en) | 1997-05-23 | 1998-12-11 | Gamera Bioscience Corporation | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
US6338820B1 (en) * | 1997-08-15 | 2002-01-15 | Alexion Pharmaceuticals, Inc. | Apparatus for performing assays at reaction sites |
US5842787A (en) * | 1997-10-09 | 1998-12-01 | Caliper Technologies Corporation | Microfluidic systems incorporating varied channel dimensions |
US6459080B1 (en) * | 1998-06-12 | 2002-10-01 | Agilent Technologies, Inc. | Miniaturized device for separating the constituents of a sample and delivering the constituents of the separated sample to a mass spectrometer |
ATE272213T1 (de) * | 1999-06-18 | 2004-08-15 | Gamera Bioscience Corp | Vorrichtungen und verfahren zur durchführung miniaturisierter homogener tests |
US6258263B1 (en) * | 1999-09-17 | 2001-07-10 | The University Of Cincinnati | Liquid chromatograph on a chip |
WO2002037096A1 (en) * | 1999-10-01 | 2002-05-10 | University Of California | Microfabricated liquid sample loading system |
US6361958B1 (en) * | 1999-11-12 | 2002-03-26 | Motorola, Inc. | Biochannel assay for hybridization with biomaterial |
JP2003533682A (ja) * | 2000-05-15 | 2003-11-11 | テカン・トレーディング・アクチェンゲゼルシャフト | 双方向流動遠心ミクロ流体装置 |
US6653122B2 (en) * | 2001-04-24 | 2003-11-25 | Dade Microscan Inc. | Indentification test device in a random access microbiological analyzer |
US6627076B2 (en) * | 2001-10-19 | 2003-09-30 | Sandia National Laboratories | Compact microchannel system |
-
2000
- 2000-06-16 AT AT00939944T patent/ATE272213T1/de not_active IP Right Cessation
- 2000-06-16 DE DE60012562T patent/DE60012562D1/de not_active Expired - Lifetime
- 2000-06-16 WO PCT/US2000/016653 patent/WO2000079285A2/en active IP Right Grant
- 2000-06-16 JP JP2001505200A patent/JP2004529312A/ja active Pending
- 2000-06-16 AU AU54949/00A patent/AU5494900A/en not_active Abandoned
- 2000-06-16 EP EP00939944A patent/EP1230544B1/de not_active Expired - Lifetime
- 2000-06-16 US US09/595,239 patent/US6582662B1/en not_active Expired - Fee Related
-
2003
- 2003-06-24 US US10/602,564 patent/US20030232403A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU5494900A (en) | 2001-01-09 |
EP1230544B1 (de) | 2004-07-28 |
US20030232403A1 (en) | 2003-12-18 |
WO2000079285A2 (en) | 2000-12-28 |
JP2004529312A (ja) | 2004-09-24 |
US6582662B1 (en) | 2003-06-24 |
EP1230544A2 (de) | 2002-08-14 |
WO2000079285A3 (en) | 2002-06-20 |
DE60012562D1 (de) | 2004-09-02 |
WO2000079285A9 (en) | 2002-10-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE272213T1 (de) | Vorrichtungen und verfahren zur durchführung miniaturisierter homogener tests | |
WO2004058406A3 (en) | Microfluidics devices and methods for diluting samples and reagents | |
WO2001087485A3 (en) | Microfluidics devices and methods for high throughput screening | |
ATE395136T1 (de) | Vorrichtungen zur durchfuehrung von miniaturisierten in vitro amplifizierungsassays | |
ATE345868T1 (de) | Zweirichtungs-durchfluss-zentrifugalmikrofluid- vorrichtungen | |
DE69634490D1 (de) | Vorrichtung und verfahren zum bewegen von fluiden mittels zentrifugalbeschleunigung bei der automatischen laborbehandlung | |
WO1998053311A3 (en) | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system | |
ATE540750T1 (de) | Mikrofluidische vorrichtung und verfahren | |
WO2006124458A3 (en) | Method and device for conducting biochemical or chemical reactions at multiple temperatures | |
WO2007081386A3 (en) | Microfluidic devices and methods of use | |
MX340077B (es) | Sistemas de fluidos de punto de cuidado y usos de los mismos. | |
PT1233830E (pt) | Teste em biocanal para hibridacao com biomaterial | |
DE60236892D1 (de) | "verbesserte bedingungen für fluidtrennungen in mikrokanälen, kapillarangetriebene fluidtrennungen" | |
BR0111125A (pt) | Moléculas de ácido nucléico de nrg-2, polipeptìdeos, e métodos diagnóstico e terapêuticos | |
DE60223635D1 (de) | Reagenzien, Verfahren und Vorrichtungen zum Nachweis von Analyten | |
EP1959255A3 (de) | Biochemische Analysatoren mit geschlossenem Regelkreis | |
DE60044490D1 (de) | Manipulation von mikroteilchen in mikrofluiden systemen | |
DE60322891D1 (de) | Mikrofluidstrukturen | |
GB0129816D0 (en) | Testing device for chemical or biochemical analysis | |
WO2007044938A3 (en) | Microfluidic samplers and methods for making and using them | |
WO2008024319A8 (en) | Microfluidic devices for nucleic acid assembly | |
ATE478342T1 (de) | Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren | |
WO2004011144A3 (en) | Transparent polymer support for electrophoresis and electrochromatography and related methods | |
DE602005009837D1 (de) | Mischer und verfahren mit mehreren t-verzweigungen und konischer apertur | |
DE60201017D1 (de) | Mikrokanalvorrichtung und verfahren |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |