ATE269330T1 - Chemische verbindungen - Google Patents

Chemische verbindungen

Info

Publication number: ATE269330T1
Authority: AT; Austria
Prior art keywords: group; alkyl; chemical compounds; chem; integer
Prior art date: 1989-04-13

Application number

AT90303852T

Other languages

English (en)

Inventor

Barry Sidney Orlek

Steven Mark Bromidge

Steven Dabbs

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-13

Filing date

1990-04-10

Publication date

2004-07-15

1989-04-13 Priority claimed from GB898908365A external-priority patent/GB8908365D0/en

1989-10-16 Priority claimed from GB898923299A external-priority patent/GB8923299D0/en

1990-04-10 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

2004-07-15 Application granted granted Critical

2004-07-15 Publication of ATE269330T1 publication Critical patent/ATE269330T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT90303852T 1989-04-13 1990-04-10 Chemische verbindungen ATE269330T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898908365A GB8908365D0 (en)	1989-04-13	1989-04-13	Novel compounds
GB898923299A GB8923299D0 (en)	1989-10-16	1989-10-16	Novel compounds

Publications (1)

Publication Number	Publication Date
ATE269330T1 true ATE269330T1 (de)	2004-07-15

Family

ID=26295213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90303852T ATE269330T1 (de)	1989-04-13	1990-04-10	Chemische verbindungen

Country Status (13)

Country	Link
US (1)	USRE35593E (de)
EP (1)	EP0392803B1 (de)
JP (3)	JP2665818B2 (de)
KR (1)	KR0185378B1 (de)
AT (1)	ATE269330T1 (de)
CA (1)	CA2014379C (de)
DE (1)	DE69034146T2 (de)
DK (1)	DK0392803T3 (de)
ES (1)	ES2219636T3 (de)
HK (1)	HK1012365A1 (de)
NZ (1)	NZ233290A (de)
PT (1)	PT93753B (de)
SG (1)	SG48315A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5362739A (en) *	1990-08-24	1994-11-08	Beecham Group P.L.C.	Azabicyclic compounds and pharmaceutical compositions containing them
GB9019095D0 (en) *	1990-09-01	1990-10-17	Beecham Group Plc	Novel compounds
US5356914A (en) *	1990-10-12	1994-10-18	Beecham Group P.L.C.	1,2,5,6-tetrahydropyridine oxime derivatives
WO1992011261A1 (en) *	1990-12-21	1992-07-09	Merck Sharp & Dohme Limited	4-azatricyclo[2.2.1.02,6]heptanes and pharmaceutical compositions
MX9300875A (es)	1992-02-20	1993-08-31	Smithkline Beecham Plc	Procedimiento para la preparacion de compuestos azabiciclicos.
GB9409718D0 (en) *	1994-05-14	1994-07-06	Smithkline Beecham Plc	Novel compounds
GB9409705D0 (en) *	1994-05-14	1994-07-06	Smithkline Beecham Plc	Novel compounds
GB9421472D0 (en) *	1994-10-25	1994-12-07	Smithkline Beecham Plc	Novel methods
AU751607B2 (en) *	1995-07-29	2002-08-22	Smithkline Beecham Plc	Method of treatment of dementia
AR004178A1 (es) *	1995-07-29	1998-11-04	Smithkline Beecham Plc	Procedimiento para la formulacion de un farmaco, una composicion farmaceutica obtenible mediante este procedimiento y el uso de la misma.
ATE263765T1 (de) *	1996-05-13	2004-04-15	Syngenta Ltd	Bicyclische amine als insektizide
GB9615628D0 (en) *	1996-07-25	1996-09-04	Smithkline Beecham Plc	Formulation
GB9619074D0 (en) *	1996-09-12	1996-10-23	Smithkline Beecham Plc	Composition
US20010003588A1 (en) *	1996-09-12	2001-06-14	Smithkline Beecham Corporation	Controlled release dosage form of [R-(Z)]-alpha-(methoxyimino)-alpha-(1-azabicyclo[2.2.2.]oct-3-yl)acetonitrile monohydrochloride
JP2001520653A (ja) *	1997-04-11	2001-10-30	エリリリーアンドカンパニー	精神分裂病の治療法
GB9815383D0 (en) *	1998-07-15	1998-09-16	Smithkline Beecham Plc	Novel method of treatment
KR20030021641A (ko) *	2001-09-07	2003-03-15	안병로	투명비누 자가제조용 키트 및 상기 키트를 이용한투명비누 자가제조방법
EP1928437A2 (de) *	2005-08-26	2008-06-11	Braincells, Inc.	Neurogenese mittels muscarinrezeptormodulation
EP2258357A3 (de)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenese mit Acetylcholinesterasehemmer
CA2625153A1 (en)	2005-10-21	2007-04-26	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
JP2009513672A (ja)	2005-10-31	2009-04-02	ブレインセルス，インコーポレイティド	神経発生のｇａｂａ受容体媒介調節
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
GB0607946D0 (en) *	2006-04-21	2006-05-31	Minster Res The Ltd	Mono and combination therapy
GB0607952D0 (en) *	2006-04-21	2006-05-31	Minster Res Ltd	Novel treatment
EP2377531A2 (de)	2006-05-09	2011-10-19	Braincells, Inc.	Neurogenese mittels Angiotensin-Modulation
CA2651862A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
EP2068872A1 (de)	2006-09-08	2009-06-17	Braincells, Inc.	Kombinationen mit einem 4-acylaminopyridin-derivat
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
KR102287645B1 (ko)	2018-12-18	2021-08-06	한화솔루션 주식회사	실리카계 촉매를 이용한 배위-음이온 개환 중합에 의한 폴리아마이드의 제조방법 및 이에 의해 제조된 폴리아마이드

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU563225B2 (en) *	1982-04-14	1987-07-02	Alizyme Therapeutics Limited	I-aza bicyclic compounds
FR2531955A1 (fr) *	1982-08-17	1984-02-24	Pharmuka Lab	Nouveau procede de preparation de derives de la quinuclidine substitues en position 3
IL81610A (en) *	1986-02-27	1990-12-23	Roussel Uclaf	Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
DE3789039T2 (de) *	1986-06-27	1994-06-09	Beecham Group Plc	Verbrückte bicyclische N-heterocyclische Verbindungen.
GB8615785D0 (en) *	1986-06-27	1986-08-06	Beecham Group Plc	Compounds
US4710508A (en) *	1986-12-08	1987-12-01	Warner-Lambert Company	O-substituted tetrahydropyridine oxime cholinergic agents
US4786648A (en) *	1986-12-08	1988-11-22	Warner-Lambert Company	O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) *	1987-03-31	1989-01-17	Warner-Lambert Company	Tetrahydropyridine oxime cholinergic agents and method of treatment
DE3854932T2 (de) *	1987-04-15	1996-06-13	Beecham Group Plc	Am Brückenkopf substituierte Azabicyclenderivate
IT1203971B (it) *	1987-04-24	1989-02-23	Roussel Maestretti Spa	Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
IT1222526B (it) *	1987-08-21	1990-09-05	Roussel Maestretti Spa	Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IT1222529B (it) *	1987-08-21	1990-09-05	Roussel Maestretti Spa	Derivati dell' ossima della 1,2,5,6-tetraidropirdin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
DE3738521C1 (de) *	1987-11-13	1988-12-01	Delta Getriebe Gmbh	Planetengetriebe
IL88156A (en) *	1987-11-13	1997-02-18	Novo Nordisk As	Azacyclic compounds their preparation and pharmaceutical compositions containing them
IT1233446B (it) *	1987-12-30	1992-04-01	Roussel Maestretti Spa	Derivati della 3 piperidinocarbaldeide ossima, loro procedimento di preparazione e loro applicazione come farmaci
PT90266B (pt) *	1988-04-15	1994-07-29	Beecham Group Plc	Processo para a preparacao de compostos azabiciclicos
IT1227436B (it) *	1988-10-28	1991-04-11	Roussel Maestretti Spa	Derivati di 1-azabicicloalcani, loro procedimento di preparazione e loro applicazione come farmaci
US4937239A (en) *	1989-02-13	1990-06-26	Warner-Lambert Company	Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents
EP0402056A3 (de) *	1989-06-06	1991-09-04	Beecham Group p.l.c.	Azabicyclische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

1990
- 1990-04-10 SG SG1996008858A patent/SG48315A1/en unknown
- 1990-04-10 ES ES90303852T patent/ES2219636T3/es not_active Expired - Lifetime
- 1990-04-10 DE DE69034146T patent/DE69034146T2/de not_active Expired - Lifetime
- 1990-04-10 AT AT90303852T patent/ATE269330T1/de not_active IP Right Cessation
- 1990-04-10 EP EP90303852A patent/EP0392803B1/de not_active Expired - Lifetime
- 1990-04-10 DK DK90303852T patent/DK0392803T3/da active
- 1990-04-11 CA CA002014379A patent/CA2014379C/en not_active Expired - Lifetime
- 1990-04-11 NZ NZ233290A patent/NZ233290A/en unknown
- 1990-04-12 PT PT93753A patent/PT93753B/pt not_active IP Right Cessation
- 1990-04-13 KR KR1019900005136A patent/KR0185378B1/ko not_active IP Right Cessation
- 1990-04-13 JP JP2096587A patent/JP2665818B2/ja not_active Expired - Lifetime
1996
- 1996-01-11 US US08/585,113 patent/USRE35593E/en not_active Expired - Lifetime
1997
- 1997-01-23 JP JP9023114A patent/JP2913467B2/ja not_active Expired - Lifetime
- 1997-01-23 JP JP9023113A patent/JP2913466B2/ja not_active Expired - Lifetime
1998
- 1998-12-15 HK HK98113519A patent/HK1012365A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69034146D1 (de)	2004-07-22
DE69034146T2 (de)	2005-07-14
KR900016211A (ko)	1990-11-12
EP0392803B1 (de)	2004-06-16
ES2219636T3 (es)	2004-12-01
HK1012365A1 (en)	1999-07-30
JPH037285A (ja)	1991-01-14
PT93753A (pt)	1990-11-20
KR0185378B1 (ko)	1999-05-01
JP2665818B2 (ja)	1997-10-22
JPH09188679A (ja)	1997-07-22
CA2014379C (en)	2000-02-08
DK0392803T3 (da)	2004-10-18
USRE35593E (en)	1997-08-19
JP2913466B2 (ja)	1999-06-28
SG48315A1 (en)	1998-04-17
NZ233290A (en)	1992-06-25
CA2014379A1 (en)	1990-10-13
AU5315990A (en)	1990-10-18
AU619969B2 (en)	1992-02-06
PT93753B (pt)	1996-08-30
JPH09188678A (ja)	1997-07-22
JP2913467B2 (ja)	1999-06-28
EP0392803A1 (de)	1990-10-17

Publication	Publication Date	Title
DE69034146D1 (de)	2004-07-22	Chemische Verbindungen
IL82553A (en)	1991-06-10	Distamycin a analogs,their preparation and pharmaceutical compositions containing them
EP0287356A3 (en)	1989-09-20	Novel compounds
DE69033935D1 (de)	2002-04-18	Bis(3,4-Dialkylbenzyliden)sorbitolacetale und diese enthaltende Zusammensetzungen
DK160877C (da)	1991-10-14	Fremgangsmaade til fremstilling af 2-penemforbindelser
ES2054020T3 (es)	1994-08-01	Compuestos biologicamente activos.
HU904785D0 (en)	1992-03-30	Process for the production of medicaments
EP0632031A4 (de)	1995-02-08
SE8604950D0 (sv)	1986-11-19	Dementia-improving and therapeutic agents
ATE64596T1 (de)	1991-07-15	Aromatische verbindungen.
MX9201279A (es)	1992-10-01	Derivados de 1-fenil-3-aza bi ciclo alquil-imidazolidin-2-onas, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
ATE115545T1 (de)	1994-12-15	Aralkylamin-verbindungen.
ATE69605T1 (de)	1991-12-15	Azolylpropenyl- und azolylmethyloxiran-derivate und diese enthaltende fungizide.
ATE104294T1 (de)	1994-04-15	Antipsychotische verbindungen.
ES2084454T3 (es)	1996-05-01	Derivados de 1-alcoxi-naftaleno-2-carboxamida con alta afinidad por el receptor 5-ht1a de serotonina
DK0543584T3 (da)	1996-07-01	Benzo(b)thiophen-2-carboxamider til behandling af forstyrrelser i centralnervesystemet
ATE66475T1 (de)	1991-09-15	Aromatische thioaether.
SE8205256D0 (sv)	1982-09-14	Tricyclische quinazolinone
BR8404545A (pt)	1985-08-06	Composto de 2-nitrometilenotetraidro-2h-1,3-tiazina n-substituida,processo para sua preparacao,composicao pesticida e processo para o combate de pragas no local

Legal Events

Date	Code	Title	Description
2004-12-15	UEP	Publication of translation of european patent specification	Ref document number: 0392803 Country of ref document: EP
2010-07-15	EELA	Cancelled due to lapse of time

Date

Code

Title

Description

2004-12-15

UEP

Publication of translation of european patent specification

Ref document number: 0392803

Country of ref document: EP

2010-07-15

EELA

Cancelled due to lapse of time