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ATE267843T1 - Verfahren zur herstellung von selbstvernetzten hyaluronsäuren und deren derivaten mittels superkritischer anti-lösungsmittel - Google Patents

Verfahren zur herstellung von selbstvernetzten hyaluronsäuren und deren derivaten mittels superkritischer anti-lösungsmittel

Info

Publication number
ATE267843T1
ATE267843T1 AT00929332T AT00929332T ATE267843T1 AT E267843 T1 ATE267843 T1 AT E267843T1 AT 00929332 T AT00929332 T AT 00929332T AT 00929332 T AT00929332 T AT 00929332T AT E267843 T1 ATE267843 T1 AT E267843T1
Authority
AT
Austria
Prior art keywords
derivatives
solvents
cross
linked hyaluronic
hyaluronic acids
Prior art date
Application number
AT00929332T
Other languages
English (en)
Inventor
Paolo Pallado
Marco Baggio
Carbonare Maurizio Dalle
Lanfranco Callegaro
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Application granted granted Critical
Publication of ATE267843T1 publication Critical patent/ATE267843T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
AT00929332T 1999-04-08 2000-03-30 Verfahren zur herstellung von selbstvernetzten hyaluronsäuren und deren derivaten mittels superkritischer anti-lösungsmittel ATE267843T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999PD000070A IT1306643B1 (it) 1999-04-08 1999-04-08 Processo per la preparazione dei composti autoreticolati dell'acidoialuronico e dei suoi derivati ottenibili mediante la tecnica
PCT/EP2000/002814 WO2000061640A1 (en) 1999-04-08 2000-03-30 Process for the preparation of autocrosslinked compounds of hyaluronic acid and the derivatives thereof by the supercritical antisolvent technique

Publications (1)

Publication Number Publication Date
ATE267843T1 true ATE267843T1 (de) 2004-06-15

Family

ID=11392546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00929332T ATE267843T1 (de) 1999-04-08 2000-03-30 Verfahren zur herstellung von selbstvernetzten hyaluronsäuren und deren derivaten mittels superkritischer anti-lösungsmittel

Country Status (9)

Country Link
US (1) US6552184B1 (de)
EP (1) EP1165619B1 (de)
JP (1) JP2002542316A (de)
AT (1) ATE267843T1 (de)
AU (1) AU769657B2 (de)
CA (1) CA2369275C (de)
DE (1) DE60011062D1 (de)
IT (1) IT1306643B1 (de)
WO (1) WO2000061640A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE376824T1 (de) 1999-01-13 2007-11-15 Alchemia Oncology Pty Ltd Verwendung von hyaluronan zur herstellung eines medikaments zur erhöhung der wirksamkeit von zytotoxischen arzneimitteln
US9066919B2 (en) * 2000-07-14 2015-06-30 Alchemia Oncology Pty Limited Hyaluronan as a chemo-sensitizer in the treatment of cancer
AUPQ879500A0 (en) * 2000-07-14 2000-08-10 Meditech Research Limited Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease
EP1427447A4 (de) * 2001-08-27 2007-05-23 Alchemia Oncology Ltd Verbesserte therapieprotokolle
AU2006274509B2 (en) 2005-07-27 2012-01-19 Alchemia Oncology Pty Limited Therapeutic protocols using hyaluronan
EP2772260A3 (de) 2005-09-07 2014-10-15 Alchemia Oncology Pty Limited Therapeutische Zusammensetzungen mit Hyaluron und therapeutischen Antikörpern sowie Behandlungsverfahren
EP1942117A1 (de) * 2006-12-29 2008-07-09 Sigea S.R.L. Derivate aus Carboxypolysacchariden
PL2209814T3 (pl) * 2007-11-13 2017-08-31 Bio-Technology General (Israel) Ltd. Proces sterylizacji przez filtrację z rozcieńczaniem dla lepkosprężystych biopolimerów
WO2020016820A1 (en) 2018-07-18 2020-01-23 Bio-Technology General (Israel) Ltd. Process of, and arrangement for, sterile filtering a non-newtonian liquid and formulation of a liquid obtainable thereby

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
ATE212545T1 (de) * 1995-03-28 2002-02-15 Fidia Advanced Biopolymers Srl Nanosphären mit einem biokompatiblen polysaccharid
US5833891A (en) * 1996-10-09 1998-11-10 The University Of Kansas Methods for a particle precipitation and coating using near-critical and supercritical antisolvents
WO1997031691A1 (en) * 1996-03-01 1997-09-04 The University Of Kansas Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents
IT1287698B1 (it) * 1996-08-29 1998-08-18 Fidia Advanced Biopolymers Srl Fili da sutura essenzialmente costituiti da derivati esterei dello acido ialuronico

Also Published As

Publication number Publication date
EP1165619A1 (de) 2002-01-02
AU769657B2 (en) 2004-01-29
US6552184B1 (en) 2003-04-22
CA2369275A1 (en) 2000-10-19
EP1165619B1 (de) 2004-05-26
CA2369275C (en) 2009-02-03
IT1306643B1 (it) 2001-10-02
AU4745900A (en) 2000-11-14
WO2000061640A1 (en) 2000-10-19
DE60011062D1 (de) 2004-07-01
JP2002542316A (ja) 2002-12-10
ITPD990070A1 (it) 2000-10-08

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