ATE254123T1 - Benzazolderivate und ihre verwendung als jnk modulatoren - Google Patents
Benzazolderivate und ihre verwendung als jnk modulatorenInfo
- Publication number
- ATE254123T1 ATE254123T1 AT00991229T AT00991229T ATE254123T1 AT E254123 T1 ATE254123 T1 AT E254123T1 AT 00991229 T AT00991229 T AT 00991229T AT 00991229 T AT00991229 T AT 00991229T AT E254123 T1 ATE254123 T1 AT E254123T1
- Authority
- AT
- Austria
- Prior art keywords
- benzazole derivatives
- jnk modulators
- jnk
- modulators
- benzazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99811207A EP1110957A1 (de) | 1999-12-24 | 1999-12-24 | Benzazolderivate und ihre Verwendung als JNK Modulatoren |
PCT/EP2000/013006 WO2001047920A1 (en) | 1999-12-24 | 2000-12-20 | Benzazole derivatives and their use as jnk modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE254123T1 true ATE254123T1 (de) | 2003-11-15 |
Family
ID=8243214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00991229T ATE254123T1 (de) | 1999-12-24 | 2000-12-20 | Benzazolderivate und ihre verwendung als jnk modulatoren |
Country Status (33)
Country | Link |
---|---|
US (2) | US7259162B2 (de) |
EP (2) | EP1110957A1 (de) |
JP (1) | JP4782344B2 (de) |
KR (2) | KR100736012B1 (de) |
CN (1) | CN1252067C (de) |
AR (1) | AR029215A1 (de) |
AT (1) | ATE254123T1 (de) |
AU (1) | AU780241B2 (de) |
BG (1) | BG65986B1 (de) |
BR (1) | BR0016911A (de) |
CA (1) | CA2394809C (de) |
CZ (1) | CZ300984B6 (de) |
DE (1) | DE60006580T2 (de) |
DK (1) | DK1240164T3 (de) |
EA (1) | EA007152B1 (de) |
EE (1) | EE05456B1 (de) |
ES (1) | ES2206351T3 (de) |
HK (1) | HK1055730A1 (de) |
HR (1) | HRP20020496B1 (de) |
HU (1) | HU229625B1 (de) |
IL (2) | IL150346A0 (de) |
MX (1) | MXPA02006242A (de) |
NO (1) | NO323146B1 (de) |
NZ (1) | NZ519423A (de) |
PL (1) | PL356634A1 (de) |
PT (1) | PT1240164E (de) |
RS (1) | RS51008B (de) |
SI (1) | SI1240164T1 (de) |
SK (1) | SK287546B6 (de) |
TR (2) | TR200302320T4 (de) |
UA (1) | UA73151C2 (de) |
WO (1) | WO2001047920A1 (de) |
ZA (1) | ZA200204427B (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1380576B1 (de) | 2001-04-16 | 2009-11-25 | Eisai R&D Management Co., Ltd. | 1h-indazolverbindungen die jnk hemmen |
AU2002331253B2 (en) | 2001-07-23 | 2008-04-03 | Laboratoires Serono Sa | Arylsulfonamide derivatives as C-JUN-N-terminal kinases (JNK'S) inhibitors |
ES2268127T3 (es) * | 2001-12-07 | 2007-03-16 | Applied Research Systems Ars Holding N.V. | Derivados de benzazol para el tratamiento de esclerodermia. |
DK1501828T3 (da) * | 2002-04-25 | 2008-03-10 | Serono Lab | Piperazinbenzothiazoler som midler til behandling af cerebrale iskæmiske lidelser eller CNS-lidelser |
CN1656079A (zh) | 2002-05-31 | 2005-08-17 | 卫材株式会社 | 吡唑化合物和含有该化合物的药物组合物 |
US7465736B2 (en) | 2002-06-14 | 2008-12-16 | Laboratoires Serono S.A. | Azole methylidene cyanide derivatives and their use as protein kinase modulators |
CA2501144C (en) | 2002-10-23 | 2015-10-06 | University Of Utah Research Foundation | Amplicon melting analysis with saturation dyes |
EP1633363B1 (de) * | 2003-05-08 | 2012-11-07 | Merck Serono SA | Pyridinyl acetonitrile |
WO2005025567A1 (en) * | 2003-09-12 | 2005-03-24 | Applied Research Systems Ars Holding N.V. | Benzothiazole derivatives for the treatment of diabetes |
US20070185104A1 (en) * | 2003-09-12 | 2007-08-09 | Applied Research Systems Ars Holding N.V. | Benzoxazole acetonitriles |
AU2004272306A1 (en) * | 2003-09-12 | 2005-03-24 | Merck Serono Sa | Benzimidazole acetonitriles |
KR20060134198A (ko) * | 2004-04-08 | 2006-12-27 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | Jnk 저해제 및 시클로스포린을 포함하는 조성물 |
US7387887B2 (en) * | 2004-04-20 | 2008-06-17 | University Of Utah Research Foundation | Nucleic acid melting analysis with saturation dyes |
US9657347B2 (en) | 2004-04-20 | 2017-05-23 | University of Utah Research Foundation and BioFire Defense, LLC | Nucleic acid melting analysis with saturation dyes |
US20060094753A1 (en) | 2004-10-29 | 2006-05-04 | Alcon, Inc. | Use of inhibitors of Jun N-terminal kinases for the treatment of glaucomatous retinopathy and ocular diseases |
US7803824B2 (en) | 2004-10-29 | 2010-09-28 | Alcon, Inc. | Use of inhibitors of Jun N-terminal kinases to treat glaucoma |
PL1812072T3 (pl) * | 2004-11-17 | 2009-04-30 | Ares Trading Sa | Benzotiazolowe formulacje oraz ich zastosowanie |
US7838522B2 (en) | 2004-11-17 | 2010-11-23 | Ares Trading S.A. | Benzothiazole formulations and use thereof |
ZA200704921B (en) | 2004-12-21 | 2008-09-25 | Serono Lab | Sulfonyl amino cyclic derivatives and use thereof |
KR20070105326A (ko) | 2005-01-31 | 2007-10-30 | 라보라뚜와르 세로노 에스. 에이. | N-하이드록시아미드 유도체 및 그것의 용도 |
US20060223807A1 (en) | 2005-03-29 | 2006-10-05 | University Of Massachusetts Medical School, A Massachusetts Corporation | Therapeutic methods for type I diabetes |
BRPI0613042A2 (pt) | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 jnk 억제제 |
EA013816B1 (ru) | 2005-09-01 | 2010-08-30 | Арес Трейдинг С.А. | Лечение неврита зрительного нерва |
ZA200804717B (en) | 2005-12-29 | 2010-02-24 | Anthrogenesis Corp | Improved composition for collecting and preserving a placental stem cells and methods of using the composition |
EP2026802A2 (de) * | 2006-06-02 | 2009-02-25 | Laboratoires Serono SA | Jnk-hemmer zur behandlung von hautkrankheiten |
US20090194268A1 (en) * | 2006-08-28 | 2009-08-06 | Dantherm Air Handling A/S | Method for manufacturing a heat exchanger |
EP2129775A1 (de) | 2007-02-12 | 2009-12-09 | Anthrogenesis Corporation | Hepatocyten und chondrocyten aus adhärenten plazentastammzellen sowie cd34+, cd45- plazentastammzellenangereicherte zellpopulationen |
CN102177157A (zh) * | 2008-08-12 | 2011-09-07 | 西特里斯药业公司 | 作为沉默调节蛋白调节剂的苯并*唑类、苯并噻唑类和相关的类似物 |
US8129396B2 (en) * | 2008-09-29 | 2012-03-06 | Telik, Inc. | 2-[1H-benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors |
AU2011352036A1 (en) | 2010-12-31 | 2013-07-18 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
CN102199147A (zh) * | 2011-03-19 | 2011-09-28 | 陕西合成药业有限公司 | 用于治疗的硝基咪唑衍生物 |
AU2012262273B2 (en) | 2011-06-01 | 2017-09-14 | Celularity Inc. | Treatment of pain using placental stem cells |
WO2014114186A1 (zh) * | 2013-01-24 | 2014-07-31 | 山东亨利医药科技有限责任公司 | Jnk抑制剂 |
EP3082422A4 (de) * | 2013-12-20 | 2017-07-05 | Biomed Valley Discoveries, Inc. | Krebsbehandlungen unter verwendung von kombinationen aus typ-1-mek- und -erk-hemmern |
KR101520378B1 (ko) * | 2014-10-02 | 2015-05-26 | (주)에프테크 | 습식 가스 스크러버의 배기유도장치 |
BR112017007178A2 (pt) | 2014-10-08 | 2017-12-19 | Ass Francaise Contre Les Myopathies | compostos de aminopiridina úteis como inibidores de prenilação de proteína |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2918369A (en) * | 1956-06-15 | 1959-12-22 | Gen Aniline & Film Corp | Non-ionic benzimidazole cyanine dyes containing in alpha-position a cyano group on the methenyl chain |
GB864131A (en) * | 1957-07-17 | 1961-03-29 | Ciba Ltd | Benzimidazolyl-acetic acid derivatives |
DE1963542A1 (de) | 1969-12-18 | 1971-06-24 | Siemens Ag | Koppelfeldanordnung fuer Fernmelde-,insbesondere Fernsprechanlagen |
JPS51123223A (en) * | 1975-04-21 | 1976-10-27 | Fuji Photo Film Co Ltd | Process for producing condensation products |
CH593954A5 (de) * | 1975-07-21 | 1977-12-30 | Ciba Geigy Ag | |
US4933341A (en) * | 1988-10-08 | 1990-06-12 | Bayer Aktiengesellschaft | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa |
EP0364765A3 (de) * | 1988-10-08 | 1991-07-17 | Bayer Ag | Substituierte 1,3,5-Triazintrione, Verfahren zu ihrer Herstellung und ihre Verwendung gegen parasitäre Protozoen |
US5523312A (en) * | 1994-09-27 | 1996-06-04 | Sterling Winthrop Inc. | Antipicornaviral agents |
US6043083A (en) | 1997-04-28 | 2000-03-28 | Davis; Roger J. | Inhibitors of the JNK signal transduction pathway and methods of use |
JP4153574B2 (ja) * | 1997-09-10 | 2008-09-24 | トーアエイヨー株式会社 | 新規なピペリジン誘導体、その製造法およびそれを含有する循環器官用剤 |
GB9721437D0 (en) * | 1997-10-10 | 1997-12-10 | Glaxo Group Ltd | Heteroaromatic compounds and their use in medicine |
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1999
- 1999-12-24 EP EP99811207A patent/EP1110957A1/de not_active Withdrawn
-
2000
- 2000-12-20 KR KR1020027007971A patent/KR100736012B1/ko not_active IP Right Cessation
- 2000-12-20 TR TR2003/02320T patent/TR200302320T4/xx unknown
- 2000-12-20 KR KR1020077008852A patent/KR20070047853A/ko active Search and Examination
- 2000-12-20 PT PT00991229T patent/PT1240164E/pt unknown
- 2000-12-20 CN CNB008187045A patent/CN1252067C/zh not_active Expired - Lifetime
- 2000-12-20 DK DK00991229T patent/DK1240164T3/da active
- 2000-12-20 AT AT00991229T patent/ATE254123T1/de active
- 2000-12-20 AU AU31616/01A patent/AU780241B2/en not_active Expired
- 2000-12-20 UA UA2002065195A patent/UA73151C2/uk unknown
- 2000-12-20 BR BR0016911-0A patent/BR0016911A/pt not_active Application Discontinuation
- 2000-12-20 EA EA200200708A patent/EA007152B1/ru not_active IP Right Cessation
- 2000-12-20 CA CA2394809A patent/CA2394809C/en not_active Expired - Lifetime
- 2000-12-20 IL IL15034600A patent/IL150346A0/xx unknown
- 2000-12-20 EE EEP200200318A patent/EE05456B1/xx not_active IP Right Cessation
- 2000-12-20 SK SK898-2002A patent/SK287546B6/sk not_active IP Right Cessation
- 2000-12-20 ES ES00991229T patent/ES2206351T3/es not_active Expired - Lifetime
- 2000-12-20 CZ CZ20022169A patent/CZ300984B6/cs not_active IP Right Cessation
- 2000-12-20 HU HU0204557A patent/HU229625B1/hu not_active IP Right Cessation
- 2000-12-20 EP EP00991229A patent/EP1240164B1/de not_active Expired - Lifetime
- 2000-12-20 TR TR2002/01509T patent/TR200201509T2/xx unknown
- 2000-12-20 RS YUP-492/02A patent/RS51008B/sr unknown
- 2000-12-20 MX MXPA02006242A patent/MXPA02006242A/es active IP Right Grant
- 2000-12-20 WO PCT/EP2000/013006 patent/WO2001047920A1/en active IP Right Grant
- 2000-12-20 SI SI200030254T patent/SI1240164T1/xx unknown
- 2000-12-20 NZ NZ519423A patent/NZ519423A/en not_active IP Right Cessation
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2002
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2003
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