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ATE244883T1 - Integriert-optischer sensor - Google Patents

Integriert-optischer sensor

Info

Publication number
ATE244883T1
ATE244883T1 AT99118309T AT99118309T ATE244883T1 AT E244883 T1 ATE244883 T1 AT E244883T1 AT 99118309 T AT99118309 T AT 99118309T AT 99118309 T AT99118309 T AT 99118309T AT E244883 T1 ATE244883 T1 AT E244883T1
Authority
AT
Austria
Prior art keywords
light
freedom
coupled
degrees
diffraction order
Prior art date
Application number
AT99118309T
Other languages
English (en)
Inventor
Rino E Kunz
Guy Voirin
Philipp N Zeller
Original Assignee
Suisse Electronique Microtech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suisse Electronique Microtech filed Critical Suisse Electronique Microtech
Application granted granted Critical
Publication of ATE244883T1 publication Critical patent/ATE244883T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Glass Compositions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT99118309T 1999-09-15 1999-09-15 Integriert-optischer sensor ATE244883T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99118309A EP1085315B1 (de) 1999-09-15 1999-09-15 Integriert-optischer Sensor

Publications (1)

Publication Number Publication Date
ATE244883T1 true ATE244883T1 (de) 2003-07-15

Family

ID=8239010

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99118309T ATE244883T1 (de) 1999-09-15 1999-09-15 Integriert-optischer sensor

Country Status (4)

Country Link
US (1) US6483096B1 (de)
EP (1) EP1085315B1 (de)
AT (1) ATE244883T1 (de)
DE (1) DE69909480T2 (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US6785433B2 (en) * 2000-08-09 2004-08-31 Artificial Sensing Instruments Asi Ag Waveguide grid array and optical measurement arrangement
FR2813121A1 (fr) * 2000-08-21 2002-02-22 Claude Weisbuch Dispositif perfectionne de support d'elements chromophores
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US6951715B2 (en) * 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7524625B2 (en) 2000-10-30 2009-04-28 Sru Biosystems, Inc. Real time binding analysis of antigens on a biosensor surface
US7094595B2 (en) 2000-10-30 2006-08-22 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7575939B2 (en) 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7875434B2 (en) 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US6707958B2 (en) * 2001-11-20 2004-03-16 Agilent Technologies, Inc. Biochemical assay device using frustrated total internal reflection modulator with an imaging optical waveguide
EP1535050A1 (de) * 2002-09-02 2005-06-01 Medical Biosystems Ltd. Biosensor
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
ATE491149T1 (de) * 2002-10-07 2010-12-15 Secr Defence Wellenleiterstruktur
US7309614B1 (en) 2002-12-04 2007-12-18 Sru Biosystems, Inc. Self-referencing biodetection method and patterned bioassays
US7027163B2 (en) * 2003-01-24 2006-04-11 General Dynamics Advanced Information Systems, Inc. Grating sensor
US20050018944A1 (en) * 2003-07-25 2005-01-27 Mozdy Eric J. Polarization modulation interrogation of grating-coupled waveguide sensors
US8298780B2 (en) 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
KR100543705B1 (ko) * 2003-11-20 2006-01-20 삼성전자주식회사 2차원적 격자가 형성되어 있는 기판을 포함하는 마이크로 어레이 및 그를 이용하는 표적 분자의 검출방법
KR100580631B1 (ko) * 2003-11-22 2006-05-16 삼성전자주식회사 산화막을 갖는 기판, 그를 이용한 표적 물질 검출 방법 및광학적 센서
KR100590548B1 (ko) * 2004-03-03 2006-06-19 삼성전자주식회사 광검출 장치
KR100634505B1 (ko) * 2004-06-16 2006-10-16 삼성전자주식회사 패턴화된 박막층을 갖는 마이크로어레이 기판 및마이크로어레이, 상기 마이크로어레이 기판 및마이크로어레이를 제조하는 방법
FR2873445A1 (fr) * 2004-07-26 2006-01-27 Genewave Soc Par Actions Simpl Dispositif de detection de la fluorescence emise par des elements chromophores dans des puits d'une plaque a puits multiples
EP1622200A1 (de) * 2004-07-26 2006-02-01 CSEM Centre Suisse d'Electronique et de Microtechnique SA Festkörper-Fotodetektor-Pixel und Fotodetektionsverfahren
US7709247B2 (en) * 2004-08-04 2010-05-04 Intel Corporation Methods and systems for detecting biomolecular binding using terahertz radiation
JP4558448B2 (ja) 2004-11-01 2010-10-06 テルモ株式会社 光導波路およびこの光導波路を用いた蛍光センサ
EP1910809A1 (de) * 2005-07-21 2008-04-16 Koninklijke Philips Electronics N.V. Vorrichtung zur erkennung von erregung mithilfe einer multiplen punktanordnung
ATE464578T1 (de) 2005-08-08 2010-04-15 Mesa Imaging Ag Verfahren und vorrichtung für redundante abstandsmessung und für das aufheben von phasenversatz
WO2007034395A2 (en) 2005-09-22 2007-03-29 Koninklijke Philips Electronics N.V. Luminescence sensor comprising at least two wire grids
TWI296044B (en) * 2005-11-03 2008-04-21 Ind Tech Res Inst Coupled waveguide-surface plasmon resonance biosensor
CH703675B1 (fr) * 2005-11-16 2012-03-15 Suisse Electronique Microtech Procédé de réalisation d'agrégats J.
TWI312414B (en) * 2005-12-16 2009-07-21 Ind Tech Res Inst Optic waveguide biiosensing device
WO2007091280A1 (en) * 2006-02-06 2007-08-16 Stmicroelectronics S.R.L. Optical apparatus and method for the inspection of nucleic acid probes by polarized radiation
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US7951583B2 (en) 2006-03-10 2011-05-31 Plc Diagnostics, Inc. Optical scanning system
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US8288157B2 (en) 2007-09-12 2012-10-16 Plc Diagnostics, Inc. Waveguide-based optical scanning systems
EP2087344B1 (de) * 2006-10-31 2019-02-27 Koninklijke Philips N.V. Biosensor mit drahtgittern zur erhöhung einer hohlraumenergie
EP2171454B1 (de) 2007-07-11 2013-03-20 X-Body, Inc. Verfahren zur identifikation von ionenkanalmodulatoren
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
DE102007033124B4 (de) * 2007-07-16 2012-12-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur optischen Detektion von Substanzen in einem flüssigen oder gasförmigen Medium
EP2250486A1 (de) * 2008-02-25 2010-11-17 Koninklijke Philips Electronics N.V. Optischer sensor zur messung der lichtemission eines analyts
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
EP2110694B1 (de) * 2008-04-18 2013-08-14 Sony DADC Austria AG Verfahren zur Herstellung eines optischen Wellenleiters, optischer Wellenleiter und Sensoranordnung
GB2461026B (en) 2008-06-16 2011-03-09 Plc Diagnostics Inc System and method for nucleic acids sequencing by phased synthesis
US8258450B1 (en) * 2008-06-26 2012-09-04 University Of South Florida Physical and chemical integrated flow imaging device
JP5656853B2 (ja) * 2008-10-27 2015-01-21 ジェナリーテ， インコーポレイテッド 光学的な探査及び検知に基づくバイオセンサ
KR20120035912A (ko) 2009-04-29 2012-04-16 피엘씨 다이아그노스틱스, 인크. 스캐닝 광원을 갖는 도파로 기반 검출 시스템
EP2537019B1 (de) 2010-02-19 2016-09-07 Pacific Biosciences Of California, Inc. Vorrichtung zur messung von analytischen reaktionen
US8994946B2 (en) 2010-02-19 2015-03-31 Pacific Biosciences Of California, Inc. Integrated analytical system and method
US8344333B2 (en) 2010-07-08 2013-01-01 The Board Of Trustees Of The University Of Illinois Multi-color fluorescence enhancement from a photonic crystal surface
EP2757374A1 (de) * 2013-01-17 2014-07-23 F. Hoffmann-La Roche AG Verfahren zur Herstellung einer äußeren Oberfläche eines planaren Wellenleiters zur Bindung von Zielproben entlang einer Vielzahl festgelegter Linien sowie planarer Wellenleiter
US9726871B2 (en) 2013-02-01 2017-08-08 Bio-Rad Laboratories, Inc. Detection system with one-piece optical element to concentrate and homogenize light
EP2824446A1 (de) 2013-07-12 2015-01-14 F. Hoffmann-La Roche AG Vorrichtung zur Verwendung bei der Bindeaffinitätserkennung
EP2827130A1 (de) * 2013-07-15 2015-01-21 F. Hoffmann-La Roche AG Vorrichtung zur Verwendung bei der Bindeaffinitätserkennung
US9410893B2 (en) 2013-11-22 2016-08-09 Taiwan Semiconductor Manufacturing Company, Ltd. Bio-chip package with waveguide integrated spectrometer
EP2884261B1 (de) 2013-12-14 2016-09-21 IMEC vzw Integrierte Fluoreszenzdetektion
WO2015096859A1 (en) * 2013-12-23 2015-07-02 CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement Guided mode resonance device
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
GB201417887D0 (en) * 2014-10-09 2014-11-26 Univ Aston Optical sensor
WO2016138427A1 (en) 2015-02-27 2016-09-01 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
JP6569856B2 (ja) * 2015-03-13 2019-09-04 パナソニックＩｐマネジメント株式会社 発光装置および内視鏡
CN114691585B (zh) 2015-05-07 2023-10-13 加利福尼亚太平洋生物科学股份有限公司 多处理器流水线架构
US10359155B2 (en) 2015-08-20 2019-07-23 Panasonic Intellectual Property Management Co., Ltd. Light-emitting apparatus
JP6748905B2 (ja) 2015-08-20 2020-09-02 パナソニックＩｐマネジメント株式会社 発光装置
CN111066263B (zh) * 2017-07-21 2023-10-03 加州理工学院 超薄平面无透镜相机
WO2019033110A1 (en) 2017-08-11 2019-02-14 California Institute Of Technology THIN-DIMENSIONAL IMAGING WITHOUT LENS USING DIRECTIONAL DETECTION ELEMENTS
EP3492909B1 (de) * 2017-12-01 2023-11-01 ams AG Chemische erfassungsvorrichtung mit fluoreszierendem sensormaterial
TWI683085B (zh) 2018-10-12 2020-01-21 國立交通大學 光學位移感測系統
TWI687676B (zh) * 2019-04-29 2020-03-11 國立中正大學 生物感測器自我補償系統
NL2023516B1 (en) 2019-05-28 2020-12-08 Illumina Inc Manufacturing a flowcell with a planar waveguide
AU2020289796A1 (en) * 2019-06-28 2021-01-28 Illumina Cambridge Limited Flowcells with linear waveguides
US20220091031A1 (en) * 2020-09-18 2022-03-24 Salvus, Llc Interferometric Detection and Quantification System and Methods of Use in Chemical Processing
DE102021112251B4 (de) 2020-12-29 2023-03-09 Interherence GmbH Opto-elektronischer Chip

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8807486D0 (en) * 1988-03-29 1988-05-05 Ares Serono Res & Dev Ltd Waveguide sensor
US6211954B1 (en) * 1996-03-30 2001-04-03 Novartis Ag Integrated optical luminescence sensor
FR2778986B1 (fr) * 1998-05-22 2000-07-21 Suisse Electronique Microtech Capteur optique utilisant une reaction immunologique et un marqueur fluorescent

Also Published As

Publication number Publication date
US6483096B1 (en) 2002-11-19
EP1085315A1 (de) 2001-03-21
DE69909480T2 (de) 2004-04-15
EP1085315B1 (de) 2003-07-09
DE69909480D1 (de) 2003-08-14

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