ATE234625T1 - Glp-1 zusammensetzungen mit verlängerter wirkdauer - Google Patents

Glp-1 zusammensetzungen mit verlängerter wirkdauer

Info

Publication number: ATE234625T1
Authority: AT; Austria
Prior art keywords: glp; extended; during compositions; compositions; during
Prior art date: 1994-12-23

Application number

AT95941606T

Other languages

English (en)

Inventor

Ejvind Jensen

Klavs Holger Jorgensen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-23

Filing date

1995-12-21

Publication date

2003-04-15

1995-12-21 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

2003-04-15 Application granted granted Critical

2003-04-15 Publication of ATE234625T1 publication Critical patent/ATE234625T1/de

Links

DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
102100025101 GATA-type zinc finger protein 1 Human genes 0.000 title 1
101710198884 GATA-type zinc finger protein 1 Proteins 0.000 title 1
230000009974 thixotropic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Diabetes (AREA)
Endocrinology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Obesity (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biophysics (AREA)
Epidemiology (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Detergent Compositions (AREA)
Soft Magnetic Materials (AREA)
Compounds Of Iron (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Adhesives Or Adhesive Processes (AREA)
Cosmetics (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT95941606T 1994-12-23 1995-12-21 Glp-1 zusammensetzungen mit verlängerter wirkdauer ATE234625T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK147894		1994-12-23
PCT/DK1995/000516 WO1996020005A1 (en)	1994-12-23	1995-12-21	Protracted glp-1 compositions

Publications (1)

Publication Number	Publication Date
ATE234625T1 true ATE234625T1 (de)	2003-04-15

Family

ID=8105257

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95941606T ATE234625T1 (de)	1994-12-23	1995-12-21	Glp-1 zusammensetzungen mit verlängerter wirkdauer

Country Status (6)

Country	Link
EP (1)	EP0796106B1 (de)
JP (1)	JPH10511365A (de)
AT (1)	ATE234625T1 (de)
AU (1)	AU4298596A (de)
DE (1)	DE69529998D1 (de)
WO (1)	WO1996020005A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5614492A (en) *	1986-05-05	1997-03-25	The General Hospital Corporation	Insulinotropic hormone GLP-1 (7-36) and uses thereof
US6849708B1 (en)	1986-05-05	2005-02-01	The General Hospital Corporation	Insulinotropic hormone and uses thereof
US7138486B2 (en)	1986-05-05	2006-11-21	The General Hospital Corporation	Insulinotropic hormone derivatives and uses thereof
FR2686899B1 (fr)	1992-01-31	1995-09-01	Rhone Poulenc Rorer Sa	Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US6284727B1 (en)	1993-04-07	2001-09-04	Scios, Inc.	Prolonged delivery of peptides
US6380357B2 (en) *	1997-12-16	2002-04-30	Eli Lilly And Company	Glucagon-like peptide-1 crystals
ATE307603T1 (de) *	1998-12-22	2005-11-15	Lilly Co Eli	Lagerstabile flüssige zusammensetzungen von glucagon-ähnlichem peptid-1
SI1140148T1 (sl) *	1998-12-22	2006-04-30	Lilly Co Eli	Stabilna formulacija raztopine glukagonu podobnega peptida-1
EP1849475A1 (de)	1999-06-21	2007-10-31	Eli Lilly & Company	Synergistische Verwendung von Thiazolidindionen mit glucagonartigem Peptid-1 und Agonisten davon zur Behandlung von nicht insulinabhängigen Diabetes
EP2067488A1 (de)	2000-04-12	2009-06-10	Human Genome Sciences, Inc.	Albuminfusionsproteine
WO2002043709A1 (fr)	2000-12-01	2002-06-06	Takeda Chemical Industries, Ltd.	Procede de production d'une preparation contenant une substance bioactive
DK1412384T3 (da)	2001-06-28	2008-04-28	Novo Nordisk As	Stabil formulering af modificeret GLP-1
CA2471363C (en)	2001-12-21	2014-02-11	Human Genome Sciences, Inc.	Albumin fusion proteins
AU2003208945B2 (en)	2002-02-20	2008-05-01	Emisphere Technologies, Inc	Method for administering GLP-1 molecules
CA2513213C (en)	2003-01-22	2013-07-30	Human Genome Sciences, Inc.	Albumin fusion proteins
JP2007524592A (ja)	2003-06-03	2007-08-30	ノボ・ノルデイスク・エー／エス	安定化された薬学的ペプチド組成物
KR101308912B1 (ko)	2003-06-03	2013-09-23	노보 노르디스크 에이/에스	안정화된 약학적 펩티드 조성물
CN113304250A (zh)	2003-11-20	2021-08-27	诺和诺德股份有限公司	对于生产和用于注射装置中是最佳的含有丙二醇的肽制剂
US20060286129A1 (en)	2003-12-19	2006-12-21	Emisphere Technologies, Inc.	Oral GLP-1 formulations
ES2442223T3 (es)	2004-08-31	2014-02-10	Novo Nordisk A/S	Uso de tris(hidroximetil) aminometano para la estabilización de péptidos, polipéptidos y proteínas
ES2735533T3 (es)	2004-11-12	2019-12-19	Novo Nordisk As	Formulaciones estables de GLP-1
GB0511269D0 (en)	2005-06-02	2005-07-13	Creative Peptides Sweden Ab	Sustained release preparation of pro-insulin C-peptide
JP6224586B2 (ja)	2012-07-10	2017-11-01	武田薬品工業株式会社	注射用製剤
CN105921431B (zh)	2016-05-04	2018-02-06	京东方科技集团股份有限公司	一种转印板清洗设备及其清洗方法
EP4360651A3 (de)	2017-08-24	2024-07-17	Novo Nordisk A/S	Glp-1-zusammensetzungen und verwendungen davon
TWI829687B (zh) *	2018-05-07	2024-01-21	丹麥商諾佛儂迪克股份有限公司	包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物
CA3165355A1 (en)	2020-02-18	2021-07-22	Tommy SANDER	Pharmaceutical formulations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1498425A1 (de) *	1986-05-05	2005-01-19	The General Hospital Corporation	Verwendung von Glucagonähnlichem-Peptid-1 (GLP-1) Derivaten zur Herstellung von pharmazeutischen Zusammensetzungen
JPS63218247A (ja) *	1987-03-06	1988-09-12	Yoshiaki Kawashima	高機能懸濁液
US5214035A (en) *	1992-04-16	1993-05-25	Hoechst-Roussel Agri-Vet Company	Thixotropic formulations
NZ250844A (en) *	1993-04-07	1996-03-26	Pfizer	Treatment of non-insulin dependant diabetes with peptides; composition

1995
- 1995-12-21 JP JP8520133A patent/JPH10511365A/ja not_active Ceased
- 1995-12-21 AT AT95941606T patent/ATE234625T1/de not_active IP Right Cessation
- 1995-12-21 WO PCT/DK1995/000516 patent/WO1996020005A1/en active IP Right Grant
- 1995-12-21 AU AU42985/96A patent/AU4298596A/en not_active Abandoned
- 1995-12-21 DE DE69529998T patent/DE69529998D1/de not_active Expired - Lifetime
- 1995-12-21 EP EP95941606A patent/EP0796106B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU4298596A (en)	1996-07-19
JPH10511365A (ja)	1998-11-04
EP0796106B1 (de)	2003-03-19
DE69529998D1 (de)	2003-04-24
EP0796106A1 (de)	1997-09-24
WO1996020005A1 (en)	1996-07-04

Publication	Publication Date	Title
ATE234625T1 (de)	2003-04-15	Glp-1 zusammensetzungen mit verlängerter wirkdauer
FI920523L (fi)	1992-08-12	Analgetiska kompositioner.
DE69005438D1 (de)	1994-02-03	Bernsteinsäureimid-Zusammensetzungen.
DE3575070D1 (de)	1990-02-08	Analgetische zusammensetzungen.
DE3482781D1 (de)	1990-08-30	Reinigungsmittelzusammensetzungen.
TR26786A (tr)	1995-05-15	Polivinilpirolidon iceren kompakt deterjan bilesimi.
DE69423670D1 (de)	2000-05-04	Siloxy-aluminoxan-Zusammensetzungen
DE69419432D1 (de)	1999-08-12	Bleichmittelzusammensetzungen
DE69109192D1 (de)	1995-06-01	Detergenszusammensetzungen.
DE69109193D1 (de)	1995-06-01	Detergenszusammensetzungen.
MA22840A1 (fr)	1993-10-01	Compositions nettoyantes.
DE69301999D1 (de)	1996-05-02	Photoresist Zusammensetzung
DE69105462D1 (de)	1995-01-12	Desinfizierende Zusammensetzung.
FI921491L (fi)	1992-04-03	Antimalariakompositioner.
DE68924884D1 (de)	1996-01-04	Tonerzusammensetzungen.
DE3873550D1 (de)	1992-09-17	Photopolymerisierbare zusammensetzungen.
DE69413612D1 (de)	1998-11-05	Wasserstoffperoxid-Zusammensetzung
DE69012475D1 (de)	1994-10-20	Lichtempfindliche Zusammensetzungen.
FI920210L (fi)	1992-07-19	Isoleringskomposition.
BR9407124A (pt)	1996-09-10	Composições contendo surfactante
EP0607899A3 (de)	1995-02-01	Positiv arbeitende Photoresistzusammensetzung.
MX9205264A (es)	1993-04-01	Composiciones oleosas.
EP0570884A3 (de)	1995-06-07	Positivarbeitende Resistzusammensetzung.
BE896665A (fr)	1983-11-04	Compositions antisolaires.
NO912598D0 (no)	1991-07-02	Hypokalori-matsammensetning.

Legal Events

Date	Code	Title	Description
2003-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties