ATE234109T1 - Cetp zur erhöhung des hdl-cholesterol-gehalts - Google Patents
Cetp zur erhöhung des hdl-cholesterol-gehaltsInfo
- Publication number
- ATE234109T1 ATE234109T1 AT96918201T AT96918201T ATE234109T1 AT E234109 T1 ATE234109 T1 AT E234109T1 AT 96918201 T AT96918201 T AT 96918201T AT 96918201 T AT96918201 T AT 96918201T AT E234109 T1 ATE234109 T1 AT E234109T1
- Authority
- AT
- Austria
- Prior art keywords
- cetp
- hdl cholesterol
- cholesterol content
- increase hdl
- stimulating
- Prior art date
Links
- KEWSCDNULKOKTG-UHFFFAOYSA-N 4-cyano-4-ethylsulfanylcarbothioylsulfanylpentanoic acid Chemical compound CCSC(=S)SC(C)(C#N)CCC(O)=O KEWSCDNULKOKTG-UHFFFAOYSA-N 0.000 title abstract 5
- 102100037637 Cholesteryl ester transfer protein Human genes 0.000 title abstract 5
- 101000880514 Homo sapiens Cholesteryl ester transfer protein Proteins 0.000 title abstract 5
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 235000012000 cholesterol Nutrition 0.000 title abstract 2
- 230000028993 immune response Effects 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 230000004936 stimulating effect Effects 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 108010058846 Ovalbumin Proteins 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 229940092253 ovalbumin Drugs 0.000 abstract 1
- 230000004044 response Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Color Television Image Signal Generators (AREA)
- Materials For Photolithography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48245495A | 1995-06-06 | 1995-06-06 | |
| PCT/US1996/009143 WO1996039168A1 (en) | 1995-06-06 | 1996-06-05 | Method for increasing hdl cholesterol level |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234109T1 true ATE234109T1 (de) | 2003-03-15 |
Family
ID=23916145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96918201T ATE234109T1 (de) | 1995-06-06 | 1996-06-05 | Cetp zur erhöhung des hdl-cholesterol-gehalts |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7074407B1 (de) |
| EP (1) | EP0831881B1 (de) |
| JP (1) | JP3910635B2 (de) |
| AT (1) | ATE234109T1 (de) |
| CA (1) | CA2223177A1 (de) |
| DE (1) | DE69626642T2 (de) |
| DK (1) | DK0831881T3 (de) |
| ES (1) | ES2190470T3 (de) |
| WO (1) | WO1996039168A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410022B1 (en) | 1995-05-01 | 2002-06-25 | Avant Immunotherapeutics, Inc. | Modulation of cholesteryl ester transfer protein (CETP) activity |
| EP0831881B1 (de) | 1995-06-06 | 2003-03-12 | Avant Immunotherapeutics, Inc. | Cetp zur erhöhung des hdl-cholesterol-gehalts |
| US6284533B1 (en) | 1996-05-01 | 2001-09-04 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| US6846808B1 (en) | 1996-05-01 | 2005-01-25 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| JP2001520204A (ja) * | 1997-10-20 | 2001-10-30 | アヴァント イムノセラピューティクス，インコーポレーテッド | コレステリルエステル運搬タンパク質（ｃｅｔｐ）活性を調節するための異種ｃｅｔｐ |
| US6300308B1 (en) * | 1997-12-31 | 2001-10-09 | Board Of Regents, The University Of Texas System | Methods and compositions for inducing autoimmunity in the treatment of cancers |
| WO2002032935A1 (es) * | 1999-12-13 | 2002-04-25 | Universidad Nacional Autonoma De Mexico | Metodo inmunoenzimatico para cuantificar |
| MX347400B (es) * | 2012-06-29 | 2017-04-18 | Univ Nac Autónoma De México | Vacuna de aplicacion nasal contra el desarrollo de la enfermedad aterosclerotica y el higado graso. |
| TW201627318A (zh) | 2014-10-22 | 2016-08-01 | 臺北醫學大學 | 膽固醇酯轉運蛋白抗原肽及其融合蛋白以及其組合物及應用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6143305A (en) | 1973-05-07 | 2000-11-07 | The Ohio State University | Antigenically modified polypeptides composition |
| US5126399A (en) | 1986-04-30 | 1992-06-30 | Board Of Regents, The University Of Texas System | Methods and compositions for the preparation and use of site-directed immunologic reagents |
| US5338829A (en) | 1988-04-20 | 1994-08-16 | Trustees Of The University Of Pennsylvania | Peptides derived from human immunodeficiency virus-1 GP160 |
| GB8812214D0 (en) | 1988-05-24 | 1988-06-29 | Hoffmann La Roche | Use of peptide from circumsporozoite protein of p falciparum as universally recognized t-cell epitope |
| US5242687A (en) | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5264341A (en) * | 1989-08-30 | 1993-11-23 | Eli Lilly And Company | Selective cloning for high monoclonal antibody secreting hybridomas |
| CA2098101A1 (en) | 1990-12-10 | 1992-06-10 | Carl R. Alving | A vaccine against cholesterol to prevent hypercholesterolemia and atherosclerosis |
| EP0618803A4 (de) * | 1991-12-19 | 1995-03-22 | Southwest Found Biomed Res | Polypeptide als inhibitoren gegen cholesterylester-transferase, antikörper gegen die synthetischen polypeptide und prophylaktische und therapeutische behandlungsweisen der atherosklerose. |
| WO1993023076A1 (en) | 1992-05-20 | 1993-11-25 | The Johns-Hopkins University | Alternative receptor therapy |
| US5279540A (en) | 1992-09-24 | 1994-01-18 | Davidson Michael H | Method for reducing the risk of atherosclerosis |
| US5618683A (en) | 1993-04-13 | 1997-04-08 | Brocia; Robert W. | Diagnostic kit for cholesteryl ester transfer protein (CETP) activity measurement and a new synthetic particle used therein |
| ES2180576T3 (es) | 1993-04-27 | 2003-02-16 | United Biomedical Inc | Construcciones peptidicas de lhrh inmunogenicas y estimuladores de inmunidad universales sinteticos para vacunas. |
| US5759551A (en) | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| WO1995004755A1 (en) * | 1993-08-04 | 1995-02-16 | Southwest Foundation For Biomedical Research | Cetp inhibitor polypeptide, antibodies against the synthetic polypeptide and prophylactic and therapeutic anti-atherosclerosis treatments |
| DK96493D0 (da) | 1993-08-26 | 1993-08-26 | Mouritsen Og Elsner Aps | Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden |
| EP0733061A1 (de) | 1994-11-12 | 1996-09-25 | LG Chemical Limited | Peptidinhibitoren des Cholesterylesther - Transferprotein und prophylaktische und therapeutische anti - artheriosklerose Agenten |
| US5705388A (en) | 1994-12-23 | 1998-01-06 | Ribozyme Pharmaceuticals, Inc. | CETP Ribozymes |
| US6410022B1 (en) | 1995-05-01 | 2002-06-25 | Avant Immunotherapeutics, Inc. | Modulation of cholesteryl ester transfer protein (CETP) activity |
| EP0831881B1 (de) | 1995-06-06 | 2003-03-12 | Avant Immunotherapeutics, Inc. | Cetp zur erhöhung des hdl-cholesterol-gehalts |
| JP2001508760A (ja) | 1996-05-01 | 2001-07-03 | アヴァント イムノセラピユーティクス，インコーポレーテッド | アテローム性動脈硬化症治療用のプラスミド型ワクチン |
| US6284533B1 (en) | 1996-05-01 | 2001-09-04 | Avant Immunotherapeutics, Inc. | Plasmid-based vaccine for treating atherosclerosis |
| US5994310A (en) | 1998-09-03 | 1999-11-30 | Bayer Corporation | Peptide ligands for affinity purification of human Factor VIII |
-
1996
- 1996-06-05 EP EP96918201A patent/EP0831881B1/de not_active Expired - Lifetime
- 1996-06-05 WO PCT/US1996/009143 patent/WO1996039168A1/en active IP Right Grant
- 1996-06-05 ES ES96918201T patent/ES2190470T3/es not_active Expired - Lifetime
- 1996-06-05 DK DK96918201T patent/DK0831881T3/da active
- 1996-06-05 AT AT96918201T patent/ATE234109T1/de not_active IP Right Cessation
- 1996-06-05 DE DE69626642T patent/DE69626642T2/de not_active Expired - Fee Related
- 1996-06-05 CA CA002223177A patent/CA2223177A1/en not_active Abandoned
- 1996-06-05 JP JP50153397A patent/JP3910635B2/ja not_active Expired - Fee Related
-
2000
- 2000-03-10 US US09/523,033 patent/US7074407B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11507910A (ja) | 1999-07-13 |
| EP0831881B1 (de) | 2003-03-12 |
| DE69626642T2 (de) | 2004-01-29 |
| ES2190470T3 (es) | 2003-08-01 |
| AU715410B2 (en) | 2000-02-03 |
| US7074407B1 (en) | 2006-07-11 |
| JP3910635B2 (ja) | 2007-04-25 |
| AU6091296A (en) | 1996-12-24 |
| DK0831881T3 (da) | 2003-07-07 |
| WO1996039168A1 (en) | 1996-12-12 |
| CA2223177A1 (en) | 1996-12-12 |
| DE69626642D1 (de) | 2003-04-17 |
| EP0831881A1 (de) | 1998-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ314058A (en) | Use of ganglioside-KLH conjugate vaccines with QS-21 to treat cancer | |
| IL111134A0 (en) | Immunological tolerance-inducing agent | |
| AU2002302255A1 (en) | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases | |
| MXPA02005576A (es) | Vacuna para la prevencion y tratamiento de la enfermedad de alzheimer y otras enfermedades relacionadas con amiloides. | |
| EA199700272A1 (ru) | Вакцины, содержащие сапонин и стерин | |
| IL125590A (en) | Peptide immunogens, process for their preparation and use thereof as vaccines against allergies | |
| EP0866133A3 (de) | Einer Gruppe B Streptococcus Impfstoff | |
| DE69738138D1 (de) | Induktion von immunologischer Toleranz gegen einen therapeutischen Antikörper durch Varianten des therapeutischen Antikörpers | |
| OA09802A (en) | Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus. | |
| ATE234109T1 (de) | Cetp zur erhöhung des hdl-cholesterol-gehalts | |
| HK1005541A1 (en) | Treatment of helicobacter associated gastroduodenal disease | |
| ATE261314T1 (de) | P53 impfstoff | |
| BR0312808A (pt) | Proteìna de fusão igg fc/hiv-gp120/c3d | |
| AU7237391A (en) | Carrier-bound recombinant protein, process for producing it and its use as an immunogen and vaccine | |
| GR3025341T3 (en) | Improved adjuvants and vaccines | |
| ZA915230B (en) | Ehv-4 glycoprotein vaccine | |
| WO1999065518A3 (en) | Lt and ct in parenteral immunization methods against helicobacter infection | |
| GB9818133D0 (en) | Vaccine | |
| FI932759A0 (fi) | Anvaendningen av IL-4 foer oekning av pao vacciners immunogener verkande immunreaktioner | |
| AU6461594A (en) | Induction of protection against viral infection | |
| WO2002004497A3 (en) | Multiple antigenic peptides immunogenic against streptococcus pneumoniae | |
| WO2000018429A3 (en) | Vaccine based on attenuated $i(haemophilus somnus) | |
| KR970074790A (ko) | 합성 펩티드를 함유하는 녹농균 백신 및 이것으로부터 생산된 치료제 | |
| MX9707295A (es) | Metodo para mejorar la respuesta de los anticuerpos a los antigenos especificos con interleucina-10. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0831881 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |