ATE230389T1 - Angiogenese inhibitoren - Google Patents

Angiogenese inhibitoren

Info

Publication number: ATE230389T1
Authority: AT; Austria
Prior art keywords: angiogenesis inhibitors; angiogenesis; inhibitors
Prior art date: 1995-10-25

Application number

AT99102501T

Other languages

English (en)

Inventor

Chiho Fukiage

Mitsuyoshi Azuma

Jun Rui Inoue

Masayuki Nakamura

Yuka Yoshida

Original Assignee

Senju Pharma Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-25

Filing date

1996-10-23

Publication date

2003-01-15

1996-10-23 Application filed by Senju Pharma Co filed Critical Senju Pharma Co

2003-01-15 Application granted granted Critical

2003-01-15 Publication of ATE230389T1 publication Critical patent/ATE230389T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT99102501T 1995-10-25 1996-10-23 Angiogenese inhibitoren ATE230389T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP27748595		1995-10-25
JP24804696		1996-09-19

Publications (1)

Publication Number	Publication Date
ATE230389T1 true ATE230389T1 (de)	2003-01-15

Family

ID=26538555

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT99106760T ATE239698T1 (de)	1995-10-25	1996-10-23	Angiogenese hemmer
AT99102501T ATE230389T1 (de)	1995-10-25	1996-10-23	Angiogenese inhibitoren
AT96116994T ATE230275T1 (de)	1995-10-25	1996-10-23	Angiogense-inhibitor

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT99106760T ATE239698T1 (de)	1995-10-25	1996-10-23	Angiogenese hemmer

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT96116994T ATE230275T1 (de)	1995-10-25	1996-10-23	Angiogense-inhibitor

Country Status (13)

Country	Link
US (2)	US6057290A (de)
EP (2)	EP0927716B1 (de)
AR (1)	AR004694A1 (de)
AT (3)	ATE239698T1 (de)
AU (1)	AU716495B2 (de)
BR (1)	BR9605267A (de)
CA (1)	CA2188817C (de)
DE (3)	DE69625622T2 (de)
ES (2)	ES2190139T3 (de)
HU (1)	HUP9602943A3 (de)
MX (1)	MX9605156A (de)
NO (1)	NO964514L (de)
PL (1)	PL316669A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997003060A1 (fr) *	1995-07-13	1997-01-30	Senju Pharmaceutical Co., Ltd.	Derives de la piperazine et leurs utilisations
US6214800B1 (en) *	1995-10-25	2001-04-10	Senju Pharmaceutical Co., Ltd.	Angiogenesis inhibitor
DE19718826A1 (de) *	1997-05-05	1998-11-12	Marion S Dr Eckmiller	Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung
DK1022276T3 (da) *	1997-09-04	2003-09-29	Nippon Chemiphar Co	Epoxysuccinamidderivater
US6015787A (en) *	1997-11-04	2000-01-18	New England Medical Center Hospitals, Inc.	Cell-permeable protein inhibitors of calpain
ATE400277T1 (de)	1998-03-05	2008-07-15	Senju Pharma Co	Pharmazeutische zusammenstellung zur vorbeugung und behandlung von mit zellkrankheiten des augenhintergrundes zusammenhängenden krankheiten
ATE275420T1 (de)	1998-03-20	2004-09-15	Senju Pharma Co	Verwendung von cysteinprotease inhibitoren zur herstellung eines arzneimittels zur vorgbeugung und behandlung von gehirngewebezerrütung infolge hypertensive enzephalopathie oder encephalothlipsis
GB9819860D0 (en) *	1998-09-12	1998-11-04	Zeneca Ltd	Chemical compounds
BR9916518A (pt)	1998-12-23	2002-01-29	Searle & Co	Método para tratar ou prevenir um distúrbio de neoplasia em um mamìfero em necessidade de tal tratamento ou prevenção, e, combinação compreendendo um inibidor de ciclooxigenase-2 e um ou mais agentes anti-neoplásticos
WO2000058280A1 (fr) *	1999-03-26	2000-10-05	Shionogi & Co., Ltd.	Derives de sulfonamide carbocyclique
KR20010001270A (ko)	1999-06-03	2001-01-05	복성해	혈관신생을 억제하는 새로운 이소쿠마린 유도체
US7052714B1 (en)	1999-10-13	2006-05-30	Senju Pharmaceutical Co., Ltd	Ophthalmic adhesive preparations for percutaneous adsorption
AU1735001A (en) *	1999-12-10	2001-06-18	Senju Pharmaceutical Co., Ltd.	Cyclodextrin-containing pharmaceutical composition
EP1334718A4 (de) *	2000-10-26	2007-07-18	Senju Pharma Co	Arzneimittelzusammensetzung mit einem dipeptydylaldehydderivat
JPWO2002048096A1 (ja) *	2000-12-12	2004-04-15	千寿製薬株式会社	ヒドラゾン誘導体およびその医薬用途
PL367188A1 (en)	2001-06-06	2005-02-21	Eli Lilly And Company	Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents
US7115607B2 (en) *	2001-07-25	2006-10-03	Amgen Inc.	Substituted piperazinyl amides and methods of use
DE60322856D1 (de) *	2002-03-15	2008-09-25	Senju Pharma Co
ATE473216T1 (de)	2002-03-29	2010-07-15	Senju Pharma Co	Hydroxymorpholinonderivat und dessen medizinische verwendung
EP1354586A1 (de) *	2002-04-20	2003-10-22	Aventis Pharma Deutschland GmbH	Verwendung von Hydroxypyridon Derivaten zur Wundheilung
ES2332363T3 (es) *	2002-07-22	2010-02-03	Senju Pharmaceutical Co., Ltd.	Nuevos derivados de alfa-cetoamida y su uso.
GB0314262D0 (en)	2003-06-19	2003-07-23	Univ Nottingham Trent	Novel compounds and methods of using the same
US7615556B2 (en) *	2006-01-27	2009-11-10	Bristol-Myers Squibb Company	Piperazinyl derivatives as modulators of chemokine receptor activity
US8236798B2 (en)	2009-05-07	2012-08-07	Abbott Gmbh & Co. Kg	Carboxamide compounds and their use as calpain inhibitors
WO2011105070A1 (ja)	2010-02-25	2011-09-01	パナソニック株式会社	需給制御装置、需給制御方法、およびプログラム
JP5823484B2 (ja)	2010-07-14	2015-11-25	千寿製薬株式会社	α―ケトアミド誘導体固体分散体
GB201218084D0 (en) *	2012-10-09	2012-11-21	Univ Aston	Novel compounds and methods for use in medicine
GB201220474D0 (en) *	2012-11-14	2012-12-26	Sagetis Biotech Sl	Polypeptides
WO2019217410A1 (en) *	2018-05-07	2019-11-14	Neuro Theranostics, Inc.	Compositions and methods for treating traumatic brain injury
WO2022187491A1 (en) *	2021-03-03	2022-09-09	The Texas A& M University System	Inhibitors of cysteine proteases

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS50137951A (de)	1974-04-27	1975-11-01
JPS5754157A (en)	1980-09-19	1982-03-31	Nippon Kayaku Co Ltd	L-argininal derivative and its preparation
PT84170B (pt) *	1986-01-24	1989-03-30	Sanofi Sa	Processo para a preparacao de derivados n alfa-substituidos das n alfa-aril-sulfonilaminoacil d-amidinofenil-alaninamidas
JPH0832698B2 (ja) *	1987-05-08	1996-03-29	日本ケミファ株式会社	ピペラジン誘導体
JP2536754B2 (ja) *	1987-05-08	1996-09-18	日本ケミファ株式会社	ピペラジン誘導体
JP2701932B2 (ja)	1989-04-10	1998-01-21	サントリー株式会社	タンパク質分解酵素阻害剤
US5510531A (en)	1989-04-10	1996-04-23	Suntory Limited	Proteinase inhibitor
EP0395309B1 (de) *	1989-04-28	1995-12-27	Takara Shuzo Co. Ltd.	Dem menschlichen Calpastatin ähnliches Polypeptid
CA2104602A1 (en)	1991-02-22	1992-08-23	Carl N. Hodge	Substituted .alpha.-aminoaldehydes and derivatives
EP0504938A3 (en) *	1991-03-22	1993-04-14	Suntory Limited	Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient
CA2071621C (en) *	1991-06-19	1996-08-06	Ahihiko Hosoda	Aldehyde derivatives
JP2848232B2 (ja)	1993-02-19	1999-01-20	武田薬品工業株式会社	アルデヒド誘導体
US5607831A (en)	1993-03-25	1997-03-04	The United States Of America As Represented By The Department Of Health And Human Services	In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death
US5658885A (en)	1993-04-27	1997-08-19	The Dupont Merck Pharmaceutical Company	Amidino and guanidino substituted boronic acid inhibitors of trypsin-like enzymes
JP3599287B2 (ja) *	1993-04-28	2004-12-08	三菱化学株式会社	スルホンアミド誘導体
WO1996010014A1 (en) *	1994-09-27	1996-04-04	Takeda Chemical Industries, Ltd.	Aldehyde derivatives as upsteine protease inhibitors
US5614649A (en)	1994-11-14	1997-03-25	Cephalon, Inc.	Multicatalytic protease inhibitors
EP0731107A1 (de) *	1995-02-13	1996-09-11	Takeda Chemical Industries, Ltd.	Herstellung von Aldehyd-Derivaten
JPH11505532A (ja)	1995-05-10	1999-05-21	カイロサイエンス・リミテッド	金属プロテアーゼとｔｎｆの放出を抑制するペプチド化合物およびその治療的使用
WO1997003060A1 (fr) *	1995-07-13	1997-01-30	Senju Pharmaceutical Co., Ltd.	Derives de la piperazine et leurs utilisations
KR100490807B1 (ko)	1995-11-28	2005-10-14	세파론, 인코포레이티드	시스테인및세린프로테아제의d-아미노산함유억제제

1996
- 1996-10-23 AT AT99106760T patent/ATE239698T1/de not_active IP Right Cessation
- 1996-10-23 EP EP99106760A patent/EP0927716B1/de not_active Expired - Lifetime
- 1996-10-23 DE DE69625622T patent/DE69625622T2/de not_active Expired - Lifetime
- 1996-10-23 DE DE69625575T patent/DE69625575T2/de not_active Expired - Lifetime
- 1996-10-23 AT AT99102501T patent/ATE230389T1/de not_active IP Right Cessation
- 1996-10-23 ES ES99102501T patent/ES2190139T3/es not_active Expired - Lifetime
- 1996-10-23 ES ES99106760T patent/ES2193615T3/es not_active Expired - Lifetime
- 1996-10-23 EP EP96116994A patent/EP0771565B1/de not_active Expired - Lifetime
- 1996-10-23 AT AT96116994T patent/ATE230275T1/de not_active IP Right Cessation
- 1996-10-23 DE DE69628050T patent/DE69628050T2/de not_active Expired - Lifetime
- 1996-10-24 AU AU70384/96A patent/AU716495B2/en not_active Ceased
- 1996-10-24 MX MX9605156A patent/MX9605156A/es unknown
- 1996-10-24 US US08/740,069 patent/US6057290A/en not_active Expired - Lifetime
- 1996-10-24 HU HU9602943A patent/HUP9602943A3/hu unknown
- 1996-10-24 NO NO964514A patent/NO964514L/no not_active Application Discontinuation
- 1996-10-24 CA CA2188817A patent/CA2188817C/en not_active Expired - Fee Related
- 1996-10-24 PL PL96316669A patent/PL316669A1/xx unknown
- 1996-10-25 BR BR9605267A patent/BR9605267A/pt not_active Application Discontinuation
- 1996-10-25 AR ARP960104906A patent/AR004694A1/es unknown
1999
- 1999-02-03 US US09/243,822 patent/US6551999B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69628050D1 (de)	2003-06-12
US6551999B1 (en)	2003-04-22
AU7038496A (en)	1997-05-01
PL316669A1 (en)	1997-04-28
EP0927716B1 (de)	2003-05-07
DE69625575T2 (de)	2003-09-25
NO964514D0 (no)	1996-10-24
DE69628050T2 (de)	2004-04-01
HUP9602943A2 (en)	1997-08-28
CA2188817A1 (en)	1997-04-26
ATE239698T1 (de)	2003-05-15
US6057290A (en)	2000-05-02
NO964514L (no)	1997-04-28
EP0771565A2 (de)	1997-05-07
HUP9602943A3 (en)	1998-03-02
EP0771565A3 (de)	1998-11-04
DE69625622D1 (de)	2003-02-06
ES2190139T3 (es)	2003-07-16
ES2193615T3 (es)	2003-11-01
BR9605267A (pt)	1998-07-21
CA2188817C (en)	2010-01-26
ATE230275T1 (de)	2003-01-15
EP0927716A1 (de)	1999-07-07
DE69625575D1 (de)	2003-02-06
DE69625622T2 (de)	2003-08-14
AR004694A1 (es)	1999-03-10
MX9605156A (es)	1998-05-31
AU716495B2 (en)	2000-02-24
EP0771565B1 (de)	2003-01-02

Publication	Publication Date	Title
ATE230389T1 (de)	2003-01-15	Angiogenese inhibitoren
FI963597L (fi)	1996-11-14	Isoprenyylitransferaasi-inhibiittoreita
NO972930D0 (no)	1997-06-23	Fibronectin-adhesjonsinhibitorer
FI972160A0 (fi)	1997-05-21	Matriisimetalloproteaasi-inhibiittorit
NO962381L (no)	1996-12-09	Spiss-beskytter-innretning
DE59609887D1 (de)	2003-01-02	Substituierte cyanophenyluracile
PT858464E (pt)	2003-08-29	Inibidores de trombina
NO980643D0 (no)	1998-02-16	Propylendopeptidase inhibitorer
DE59610332D1 (de)	2003-05-15	Substituierte aminouracile
PT863916E (pt)	2002-07-31	Tripeptidos de polifluoroalquil triptofano inibidores de trombina
BR9608890A (pt)	1999-06-15	N-metilenotiouréias substituídas
BR9609319A (pt)	1999-07-06	Carbonilaminofeniluracilas substituídas
BR9603376A (pt)	1998-05-12	Tetrahidro-5-nitro-pirimidinas substituídas
BR9610514A (pt)	1999-03-30	Inibidores cicloantihelmínticos
DE59607732D1 (de)	2001-10-25	Substituierte benzylidencyanessigester
DE59607958D1 (de)	2001-11-22	Substituierte phenyluracile
FI1943U1 (fi)	1995-06-09	Bomsystem till skogmaskin
KR970703937A (ko)	1997-08-09	금속단백질 분해효소 억제제(Metallproteinase inhibitors)
CY2007006I2 (el)	2009-11-04	Αναστολεις συνθεσεις απολιποπρωτεϊνης-β
NO950285D0 (no)	1995-01-26	Teletorgteknikk
BR9503278A (pt)	1996-04-30	Dispositivos absorventes bucais
FI2196U1 (fi)	1995-11-24	Snoestyrningsblad till snoeslunga
FI2002U1 (fi)	1995-07-07	Haollare till spoestaell
FI2187U1 (fi)	1995-11-21	Hoerndetalj till plaottlaoda
FI1863U1 (fi)	1995-04-19	Vaeggkonstruktion till timmerhus

Legal Events

Date	Code	Title	Description
2003-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties