ATE227980T1 - Zubereitung mit verzögerter freisetzung und deren herstellung - Google Patents
Zubereitung mit verzögerter freisetzung und deren herstellungInfo
- Publication number
- ATE227980T1 ATE227980T1 AT97908520T AT97908520T ATE227980T1 AT E227980 T1 ATE227980 T1 AT E227980T1 AT 97908520 T AT97908520 T AT 97908520T AT 97908520 T AT97908520 T AT 97908520T AT E227980 T1 ATE227980 T1 AT E227980T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- release preparation
- sustained release
- sustained
- dispersing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7301696 | 1996-03-28 | ||
PCT/JP1997/001041 WO1997035563A2 (en) | 1996-03-28 | 1997-03-27 | Sustained-release preparation and its production |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE227980T1 true ATE227980T1 (de) | 2002-12-15 |
Family
ID=13506129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97908520T ATE227980T1 (de) | 1996-03-28 | 1997-03-27 | Zubereitung mit verzögerter freisetzung und deren herstellung |
Country Status (8)
Country | Link |
---|---|
US (2) | US6190702B1 (de) |
EP (1) | EP0889722B1 (de) |
AT (1) | ATE227980T1 (de) |
AU (1) | AU2043297A (de) |
CA (1) | CA2241322C (de) |
DE (1) | DE69717263T2 (de) |
DK (1) | DK0889722T3 (de) |
WO (1) | WO1997035563A2 (de) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000500744A (ja) | 1995-11-09 | 2000-01-25 | マイクロバイオロジカル リサーチ オーソリティー | ワクチン接種および遺伝子治療のためのマイクロカプセル化dna |
US6270795B1 (en) | 1995-11-09 | 2001-08-07 | Microbiological Research Authority | Method of making microencapsulated DNA for vaccination and gene therapy |
US6287587B2 (en) | 1997-07-15 | 2001-09-11 | Takeda Chemical Industries, Ltd. | Process for producing sustained-release preparation by in-water drying |
IL136951A0 (en) | 1998-01-16 | 2001-06-14 | Takeda Chemical Industries Ltd | Sustained-release composition, method of its production and use thereof |
EP1049458B1 (de) * | 1998-01-21 | 2003-03-26 | Takeda Chemical Industries, Ltd. | Verfahren zur gerfriertrocknung von präparaten mit verzörgerter wirkstoffabgabe |
AU744354B2 (en) | 1998-03-20 | 2002-02-21 | Takeda Chemical Industries Ltd. | Sustained-release preparation of physiologically active polypeptide and production thereof |
GB9810236D0 (en) | 1998-05-13 | 1998-07-08 | Microbiological Res Authority | Improvements relating to encapsulation of bioactive agents |
JP2003519651A (ja) * | 2000-01-14 | 2003-06-24 | ブラウン ユニバーシティ リサーチ ファウンデーション | 微紛化凍結乾燥粒子 |
US7029700B2 (en) | 2000-01-14 | 2006-04-18 | Brown University Research Foundation | Micronized freeze-dried particles |
ATE328605T1 (de) | 2000-03-24 | 2006-06-15 | Genentech Inc | Verwendung von insulin zur behandlung von knorpelkrankheiten |
US7488761B2 (en) * | 2000-08-07 | 2009-02-10 | Orthogen Llc | Polymer containing calcium sulfate particles for bone augmentation |
US20080233165A1 (en) * | 2000-08-07 | 2008-09-25 | Biolok International, Inc. | Time release calcium sulfate and growth factor matrix for bone augmentation |
US6824822B2 (en) * | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
CA2433037C (en) | 2000-12-28 | 2010-12-21 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
JP2002265383A (ja) * | 2001-03-14 | 2002-09-18 | Mitsubishi Pharma Corp | インターフェロンα注射用液状製剤 |
WO2002078673A1 (fr) * | 2001-03-29 | 2002-10-10 | Takeda Chemical Industries, Ltd. | Procede de production d'un medicament sous forme de granules fins |
US20040126900A1 (en) * | 2001-04-13 | 2004-07-01 | Barry Stephen E | High affinity peptide- containing nanoparticles |
US6887897B2 (en) | 2001-07-31 | 2005-05-03 | Mission Pharmacal Company | Calcium glutarate supplement and phosphorus binder |
CA2471521C (en) * | 2001-12-26 | 2010-11-02 | Takeda Chemical Industries, Ltd. | Novel microsphere and method for production thereof |
LT2891666T (lt) | 2002-10-16 | 2017-10-10 | Purdue Pharma L.P. | Antikūnai, kurie prisiriša su ląstelėmis susijusį ca 125/o722p ir jų naudojimo būdas |
AU2003286472A1 (en) | 2002-10-17 | 2004-05-04 | Alkermes Controlled Therapeutics, Inc. Ii | Microencapsulation and sustained release of biologically active polypeptides |
US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
US7456254B2 (en) * | 2004-04-15 | 2008-11-25 | Alkermes, Inc. | Polymer-based sustained release device |
DK1734971T3 (da) * | 2004-04-15 | 2012-02-13 | Alkermes Pharma Ireland Ltd | Indretning på polymerbasis med forsinket frigivelse |
US20060110423A1 (en) * | 2004-04-15 | 2006-05-25 | Wright Steven G | Polymer-based sustained release device |
US8075910B2 (en) * | 2004-05-20 | 2011-12-13 | Pbm Pharmaceuticals, Inc. | Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
DE102005017777A1 (de) * | 2005-04-13 | 2006-10-19 | Pharmasol Gmbh | Verfahren zur schonenden Herstellung von hochfeinen Partikelsuspensionen |
DE502006005846D1 (de) * | 2005-04-13 | 2010-02-25 | Abbott Gmbh & Co Kg | Verfahren zur schonenden herstellung hochfeiner partikelsuspensionen und hochfeiner partikel sowie deren verwendung |
PT2359808E (pt) | 2006-08-09 | 2013-08-28 | Intarcia Therapeutics Inc | Sistemas de entrega osmótica e montagens de pistão |
AU2008231093A1 (en) * | 2007-03-22 | 2008-10-02 | Alkermes, Inc. | Coacervation process |
PL2157967T3 (pl) | 2007-04-23 | 2013-06-28 | Intarcia Therapeutics Inc | Formulacje zawiesinowe peptydów insulinotropowych i ich zastosowania |
US20080317865A1 (en) * | 2007-06-20 | 2008-12-25 | Alkermes, Inc. | Quench liquids and washing systems for production of microparticles |
EP2044934A1 (de) * | 2007-10-01 | 2009-04-08 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Dispersion von Poloxamer-Proteinpartikeln, Herstellungsmethoden und Verwendung davon |
CA2726861C (en) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
PT2341905T (pt) * | 2008-09-04 | 2020-07-27 | Amylin Pharmaceuticals Inc | Formulações de libertação sustentada utilizando transportadores não aquosos |
CN102176900B (zh) | 2008-09-17 | 2017-09-26 | 克艾思马有限公司 | 药物组合物和相关的给药方法 |
HUE035862T2 (en) | 2009-09-28 | 2018-05-28 | Intarcia Therapeutics Inc | Rapid establishment and/or termination of substantial steady-state drug delivery |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
MA41462A (fr) | 2015-02-03 | 2021-05-12 | Chiasma Inc | Méthode de traitement de maladies |
MX2017015504A (es) | 2015-06-03 | 2018-05-15 | Intarcia Therapeutics Inc | Sistemas de colocacion y remoción de implante. |
CA3024479A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
WO2018156935A1 (en) * | 2017-02-24 | 2018-08-30 | The Regents Of The University Of California | Particle-drop structures and methods for making and using the same |
US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4774091A (en) | 1983-10-14 | 1988-09-27 | Sumitomo Pharmaceuticals Company, Ltd. | Long-term sustained-release preparation |
US5385738A (en) | 1983-10-14 | 1995-01-31 | Sumitomo Pharmaceuticals Company, Ltd. | Sustained-release injection |
US4963367A (en) | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
US4962091A (en) | 1986-05-23 | 1990-10-09 | Syntex (U.S.A.) Inc. | Controlled release of macromolecular polypeptides |
JP3116311B2 (ja) | 1990-06-13 | 2000-12-11 | エーザイ株式会社 | マイクロスフィアの製法 |
NZ240214A (en) | 1990-10-16 | 1993-02-25 | Takeda Chemical Industries Ltd | Polymer compositions comprising a polylactic acid and a copolymer of glycolic acid and a hydroxycarboxylic acid; use as carrier for prolonged release pharmaceutical compositions of water soluble drugs |
US5288502A (en) * | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
ES2151541T3 (es) | 1992-12-02 | 2001-01-01 | Alkermes Inc | Microesferas que contienen hormona del crecimiento de liberacion prolongada. |
US5589167A (en) | 1993-02-23 | 1996-12-31 | Genentech, Inc. | Excipient stabilization of polypeptides treated with organic solvents |
NZ260909A (en) * | 1993-07-05 | 1995-04-27 | Takeda Chemical Industries Ltd | Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution |
DK0724433T3 (da) | 1993-10-22 | 1999-08-30 | Genentech Inc | Fremgangsmåde til fremstilling af mikrosfærer med et tørringstrin i fluidiseret leje |
US6117455A (en) * | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
TW448055B (en) * | 1995-09-04 | 2001-08-01 | Takeda Chemical Industries Ltd | Method of production of sustained-release preparation |
EP0765660A3 (de) * | 1995-09-28 | 1998-09-23 | Takeda Chemical Industries, Ltd. | Mikrokapseln enthaltend 2-Piperazinon-1-essigsäure Verbindungen |
-
1997
- 1997-03-27 CA CA002241322A patent/CA2241322C/en not_active Expired - Fee Related
- 1997-03-27 WO PCT/JP1997/001041 patent/WO1997035563A2/en active IP Right Grant
- 1997-03-27 EP EP97908520A patent/EP0889722B1/de not_active Expired - Lifetime
- 1997-03-27 US US08/849,172 patent/US6190702B1/en not_active Expired - Lifetime
- 1997-03-27 AU AU20432/97A patent/AU2043297A/en not_active Abandoned
- 1997-03-27 DE DE69717263T patent/DE69717263T2/de not_active Expired - Lifetime
- 1997-03-27 DK DK97908520T patent/DK0889722T3/da active
- 1997-03-27 AT AT97908520T patent/ATE227980T1/de not_active IP Right Cessation
-
2001
- 2001-01-19 US US09/764,052 patent/US20010006678A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0889722A2 (de) | 1999-01-13 |
DE69717263D1 (de) | 2003-01-02 |
DE69717263T2 (de) | 2003-07-24 |
EP0889722B1 (de) | 2002-11-20 |
CA2241322A1 (en) | 1997-10-02 |
US6190702B1 (en) | 2001-02-20 |
DK0889722T3 (da) | 2003-02-10 |
CA2241322C (en) | 2009-01-13 |
US20010006678A1 (en) | 2001-07-05 |
AU2043297A (en) | 1997-10-17 |
WO1997035563A3 (en) | 1997-11-20 |
WO1997035563A2 (en) | 1997-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |