[go: up one dir, main page]

ATE214739T1 - Plättchen-spezifisches chimärisches immunglobulin - Google Patents

Plättchen-spezifisches chimärisches immunglobulin

Info

Publication number
ATE214739T1
ATE214739T1 AT89907420T AT89907420T ATE214739T1 AT E214739 T1 ATE214739 T1 AT E214739T1 AT 89907420 T AT89907420 T AT 89907420T AT 89907420 T AT89907420 T AT 89907420T AT E214739 T1 ATE214739 T1 AT E214739T1
Authority
AT
Austria
Prior art keywords
specific
immunolobulin
platele
image
specific chimeric
Prior art date
Application number
AT89907420T
Other languages
English (en)
Inventor
Barry S Coller
David M Knight
Original Assignee
Centocor Inc
Univ New York Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc, Univ New York Res Found filed Critical Centocor Inc
Application granted granted Critical
Publication of ATE214739T1 publication Critical patent/ATE214739T1/de

Links

Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04B—TRANSMISSION
    • H04B5/00—Near-field transmission systems, e.g. inductive or capacitive transmission systems
    • H04B5/20—Near-field transmission systems, e.g. inductive or capacitive transmission systems characterised by the transmission technique; characterised by the transmission medium
    • H04B5/24—Inductive coupling
    • H04B5/26—Inductive coupling using coils
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • G—PHYSICS
    • G08—SIGNALLING
    • G08B—SIGNALLING OR CALLING SYSTEMS; ORDER TELEGRAPHS; ALARM SYSTEMS
    • G08B13/00—Burglar, theft or intruder alarms
    • G08B13/22—Electrical actuation
    • G08B13/24—Electrical actuation by interference with electromagnetic field distribution
    • G08B13/2402—Electronic Article Surveillance [EAS], i.e. systems using tags for detecting removal of a tagged item from a secure area, e.g. tags for detecting shoplifting
    • G08B13/2465—Aspects related to the EAS system, e.g. system components other than tags
    • G08B13/2468—Antenna in system and the related signal processing
    • G08B13/2474—Antenna or antenna activator geometry, arrangement or layout
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01Q—ANTENNAS, i.e. RADIO AERIALS
    • H01Q7/00—Loop antennas with a substantially uniform current distribution around the loop and having a directional radiation pattern in a plane perpendicular to the plane of the loop
    • H01Q7/04—Screened antennas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Automation & Control Theory (AREA)
  • Computer Security & Cryptography (AREA)
  • Electromagnetism (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Burglar Alarm Systems (AREA)
  • Variable-Direction Aerials And Aerial Arrays (AREA)
AT89907420T 1988-05-18 1989-05-16 Plättchen-spezifisches chimärisches immunglobulin ATE214739T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19572088A 1988-05-18 1988-05-18
PCT/US1989/002106 WO1989011538A1 (en) 1988-05-18 1989-05-16 Platelet-specific chimeric immunoglobulin

Publications (1)

Publication Number Publication Date
ATE214739T1 true ATE214739T1 (de) 2002-04-15

Family

ID=22722511

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89907420T ATE214739T1 (de) 1988-05-18 1989-05-16 Plättchen-spezifisches chimärisches immunglobulin

Country Status (10)

Country Link
EP (2) EP0418316B1 (de)
JP (3) JP3115298B2 (de)
KR (1) KR940009084B1 (de)
AT (1) ATE214739T1 (de)
CA (1) CA1341357C (de)
DE (2) DE10299038I2 (de)
HK (1) HK1044563A1 (de)
LU (1) LU90955I2 (de)
NL (1) NL300102I2 (de)
WO (1) WO1989011538A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770198A (en) * 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
WO1990006133A1 (en) * 1988-11-25 1990-06-14 Centocor, Inc. Heterobifunctional antibodies having specificity for platelets and thrombolytic agents
JPH05304982A (ja) * 1991-11-08 1993-11-19 Takara Shuzo Co Ltd キメラ型抗体
US5777085A (en) * 1991-12-20 1998-07-07 Protein Design Labs, Inc. Humanized antibodies reactive with GPIIB/IIIA
DK0676965T3 (da) 1992-11-16 2007-11-19 Centocor Inc Fremgangsmåde til at reducere immunogeniciteten af variable regioner på antistoffer
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
ATE247980T1 (de) * 1993-11-05 2003-09-15 Centocor Inc Verwendung von an glycoprotein gpiib/iiia bindenden substanzen zur vermeidung von stenosis und restenosis
US5694139A (en) * 1994-06-28 1997-12-02 Sony Corporation Short-distance communication antenna and methods of manufacturing and using the short-distance communication antenna
GB9519667D0 (en) * 1995-09-27 1995-11-29 Univ Manchester Pharmaceutical composition
PL189116B1 (pl) * 1996-11-27 2005-06-30 Aventis Pharma Inc Kompozycja farmaceutyczna i zastosowanie kompozycji farmaceutycznej w stanach fizjologicznych towarzyszących zaburzeniu niedokrwienia związanego z zakrzepicą
EP1539236A4 (de) 2002-07-03 2007-07-18 Univ Pennsylvania Zusammensetzungen, verfahren und kits in verbindung mit anti-blutplättchen-autoantikörpern und inhibitoren davon
CN1230447C (zh) * 2002-07-17 2005-12-07 阮长耿 识别血小板膜糖蛋白的单克隆抗体及其在抗血栓治疗中的应用
EP2417155B1 (de) * 2009-04-06 2013-06-19 Novo Nordisk A/S Gezielte fresetzung von faktor-viii-proteinen auf thrombozyten
CA2807749C (en) * 2010-08-05 2023-02-28 Council Of Scientific & Industrial Research Protein fusion constructs possessing thrombolytic and anticoagulant properties
MX357167B (es) 2010-10-27 2018-06-28 Univ New York State Res Found Composiciones que se dirigen al dominio extracelular soluble de e-caderina y metodos relacionados para terapia de cancer.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6147500A (ja) * 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
CA1297815C (en) * 1985-06-07 1992-03-24 Barry S. Coller Fibrinogen blocking monoclonal antibody
CA1297816C (en) * 1985-06-14 1992-03-24 Barry S. Coller Platelet function inhibiting monoclonal antibody fragment

Also Published As

Publication number Publication date
LU90955I2 (en) 2002-11-11
KR900702594A (ko) 1990-12-07
EP0418316A1 (de) 1991-03-27
JPH04501503A (ja) 1992-03-19
HK1044563A1 (zh) 2002-10-25
EP1176201A2 (de) 2002-01-30
KR940009084B1 (ko) 1994-09-29
DE10299038I1 (de) 2003-02-20
WO1989011538A1 (en) 1989-11-30
DE10299038I2 (de) 2004-12-16
EP0418316B1 (de) 2002-03-20
JP2000060555A (ja) 2000-02-29
JP3115298B2 (ja) 2000-12-04
DE68929380D1 (de) 2002-04-25
NL300102I1 (nl) 2002-12-02
EP1176201A3 (de) 2002-02-06
JPH11180894A (ja) 1999-07-06
NL300102I2 (nl) 2003-04-01
DE68929380T2 (de) 2002-11-21
CA1341357C (en) 2002-05-07

Similar Documents

Publication Publication Date Title
DE68929380D1 (de) Plättchen-spezifisches chimärisches immunglobulin
AU1042192A (en) Recombinant antibodies specific for a growth factor receptor
EP1378525A3 (de) Humanisierte Antikörper die and das gleiche Antigen wie Antikörper NR-LU-13 binden und deren Verwendung in "Pretargeting" Verfahren
AU4128089A (en) Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same
ATE168013T1 (de) Humanisierte chimäre anti-''icam-1'' antikörper, herstellungsverfahren und verwendung
DE69632667D1 (de) CTLA4-Mutantmoleküle und deren Verwendung
GR3036906T3 (en) Monoclonal antibody which specifically binds to tumor vascular endothelium and uses thereof.
ATE81153T1 (de) Expressionssystem zur herstellung von chimaeren monoklonalen antikoerpern.
AU3125289A (en) Monoclonal antibodies directed against human tumor necrosis factor - receptor
GR3020610T3 (en) Monoclonal antibodies against tumor associated antigen, their preparation and use
JPS6456697A (en) Viii factor bonded domain of von willebrand's factor
AU7657387A (en) Apoprotein b-100 specific monoclonal antibodies
ES2179824T3 (es) Anticuerpos humanizados reactivos contra el antigeno gpiib/iiia.
ES2149159T3 (es) Proteinas de fusion con contenido en anticuerpos monoclonales, enlazador- y beta-glucuronidasa, destinadas a la activacion de profarmacos, su preparacion y utilizacion.
DE69020548D1 (de) Blutplättchenspezifische immunokonjugate.
HK1054682A1 (en) Platelet-specific chimeric immunoglobulin and methods of use therefor
AU2032988A (en) A genus-specific listeria antigen identified by monoclonal antibodies
WO1996040250A3 (en) Platelet-specific chimeric immunoglobulin and methods of use therefor
ATE76583T1 (de) Anti-immuntoxine gegen menschlichen eierstockkrebs und verfahren zu deren verwendung.
OA09745A (en) "Anti-oncostatin M mococlonal antibodies".
EP0554670A3 (en) Specific antibodies against activated platelets, their production and applications in diagnostics and therapeutics