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ATE210452T1 - Entzündungshemmende tolerogene und immunoinhibitorische eigenschaften von karbohydrate bindende peptide - Google Patents

Entzündungshemmende tolerogene und immunoinhibitorische eigenschaften von karbohydrate bindende peptide

Info

Publication number
ATE210452T1
ATE210452T1 AT93921770T AT93921770T ATE210452T1 AT E210452 T1 ATE210452 T1 AT E210452T1 AT 93921770 T AT93921770 T AT 93921770T AT 93921770 T AT93921770 T AT 93921770T AT E210452 T1 ATE210452 T1 AT E210452T1
Authority
AT
Austria
Prior art keywords
carbohydrate binding
binding peptides
tolerogene
inflammatory
betagal
Prior art date
Application number
AT93921770T
Other languages
English (en)
Inventor
Louis D Heerze
Glen D Armstrong
Richard Smith
Original Assignee
Alberta Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/995,503 external-priority patent/US5453272A/en
Application filed by Alberta Res Council filed Critical Alberta Res Council
Application granted granted Critical
Publication of ATE210452T1 publication Critical patent/ATE210452T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT93921770T 1992-10-02 1993-10-04 Entzündungshemmende tolerogene und immunoinhibitorische eigenschaften von karbohydrate bindende peptide ATE210452T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95604392A 1992-10-02 1992-10-02
US07/995,503 US5453272A (en) 1992-10-02 1992-12-21 Lectin derived carbohydrate binding-peptide
PCT/CA1993/000415 WO1994007517A1 (en) 1992-10-02 1993-10-04 Anti-inflammatory tolerogenic and immunoinhibiting properties of carbohydrate binding-peptides

Publications (1)

Publication Number Publication Date
ATE210452T1 true ATE210452T1 (de) 2001-12-15

Family

ID=27130371

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93921770T ATE210452T1 (de) 1992-10-02 1993-10-04 Entzündungshemmende tolerogene und immunoinhibitorische eigenschaften von karbohydrate bindende peptide

Country Status (9)

Country Link
US (5) US5833990A (de)
EP (1) EP0666758B1 (de)
JP (1) JPH08501569A (de)
AT (1) ATE210452T1 (de)
AU (1) AU686116B2 (de)
CA (1) CA2145881C (de)
DE (1) DE69331331T2 (de)
ES (1) ES2169724T3 (de)
WO (1) WO1994007517A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE210452T1 (de) * 1992-10-02 2001-12-15 Alberta Res Council Entzündungshemmende tolerogene und immunoinhibitorische eigenschaften von karbohydrate bindende peptide
JPH07101977A (ja) * 1993-10-05 1995-04-18 Kureha Chem Ind Co Ltd ホルモン作用を軽減した新規なエストラジオール誘導体及びその増殖因子阻害剤
IL111866A (en) * 1994-12-04 2005-03-20 Yeda Res & Dev Pharmaceutical compositions comprising the b-oligomer of pertussis toxin
EP1073459A4 (de) * 1998-04-27 2005-01-19 Biocrystal Ltd Zusammensetzungen und methoden zur tolerierung in immunkomplex-vermittelten krankheitsverläufen
AU3239400A (en) * 1999-02-22 2000-09-04 University Of Iowa Research Foundation, The Method for inhibiting inflammatory responses
KR100428469B1 (ko) * 2001-04-17 2004-04-27 한국과학기술연구원 강한 결합력을 가지는 당 특이적 펩타이드 및 그의 제조방법
US20030033413A1 (en) * 2001-06-19 2003-02-13 Willson Alan N. Mobile wireless local area network
US20050026866A1 (en) * 2002-08-02 2005-02-03 Pawelek John M. Agents and methods for treatment of disease by oligosaccharide targeting agents
US20040072992A1 (en) * 2002-08-30 2004-04-15 Sachiko Machida Novel peptide capable of specifically acting on biological membrane
WO2005107491A2 (en) * 2004-05-05 2005-11-17 Northeastern University Multi-lectin affinity chromatography and uses thereof
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
US9169327B2 (en) * 2008-03-12 2015-10-27 Rowan University Targeting of podoplanin with lectin for use in the prevention and treatment of cancer
EP2344196B1 (de) 2008-09-12 2018-11-14 University Court of The University of St Andrews Kohlenhydrat-bindende moleküle
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EP3096791B1 (de) 2014-01-24 2023-12-20 Pneumagen Ltd. Immunmodulierende verbindungen
US11043823B2 (en) * 2017-04-06 2021-06-22 Tesla, Inc. System and method for facilitating conditioning and testing of rechargeable battery cells
EP3849586A1 (de) * 2018-09-16 2021-07-21 Unichem Laboratories Ltd Protein zur behandlung von entzündlichen erkrankungen

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JPS61165334A (ja) * 1984-08-03 1986-07-26 メデイサ−チ、エス、ア− ウイルスの感染活性の抑制方法および組成物
US4742046A (en) * 1984-08-03 1988-05-03 Medisearch S.A. Methods and compositions for inhibiting the infectious activity of viruses
US5157023A (en) * 1984-08-21 1992-10-20 Lipton James M Antipyretic and anti-inflammatory lys pro val compositions and method of use
CA1340373C (en) * 1986-01-28 1999-02-02 Rino Rappuoli Cloning and sequencing of the dna fragment which codes for the five subunits of the pertussis toxin, a hybrid plasmid containing the dna fragment and micro-organisms transformed by the hybrid plasmid and capable of expressing all or some of the subunits of the pertussis toxin
US5244657A (en) * 1987-11-24 1993-09-14 Connaught Laboratories Limited Genetic detoxification of pertussis toxin
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
NL8703107A (nl) * 1987-12-22 1989-07-17 Nederlanden Staat Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten.
AU631351B2 (en) * 1988-04-20 1992-11-26 Massachusetts Health Research Institute, Inc. (Mhri) Pertussis toxoid vaccine
US5081034A (en) * 1988-11-14 1992-01-14 Brigham & Women's Hospital Cloned genes which encode elam-1
US5198424A (en) * 1989-03-08 1993-03-30 Board Of Regents Of The University Of Oklahoma Functionally active selectin-derived peptides
EP0436726B1 (de) * 1989-08-03 1993-10-20 Eisai Co., Ltd. Verfahren zur photostabilisierung von augenspüllösungen
DE3926912A1 (de) * 1989-08-16 1991-02-21 Bosch Gmbh Robert Elektromagnetischer drehsteller
EP0504257A4 (en) * 1989-11-29 1993-03-03 Brigham And Women's Hospital (ala il-8) 77 as a leukocyte adhesion inhibitor
ATE143692T1 (de) 1989-11-29 1996-10-15 Smithkline Beecham Biolog Neuer impfstoff
US5196511A (en) * 1989-12-01 1993-03-23 The Scripps Research Institute Peptides and antibodies that inhibit integrin-ligand binding
WO1991019501A1 (en) * 1990-06-15 1991-12-26 Cytel Corporation Intercellular adhesion mediators
DK0714912T3 (da) 1990-07-17 2003-02-03 Univ Oklahoma Funktionelt aktive selektin-deriverede peptider og ligander for GMP-140
US5211937A (en) * 1990-07-30 1993-05-18 Glycomed Incorporated Method of determining a site of inflammation utilizing elam-1 ligands
NZ240316A (en) * 1990-10-25 1996-12-20 Univ Michigan Compound for treating disease mediated by the elaboration of elam-1 on endothelial cells
HUT64476A (en) * 1990-11-23 1994-01-28 Gen Hospital Corp Process for inhibiting interacton between proteins and carbohydrate causing cell-adhesion
EP0563130B1 (de) * 1990-12-21 1995-07-12 Minnesota Mining And Manufacturing Company Zweistreifen-xor-strichcode und optischer leser
JPH06508823A (ja) * 1991-03-11 1994-10-06 ニュー　イングランド　メディカル　センター　ホスピタルズ，インコーポレイテッド ２，６シアル酸成分を含むインヒビターによるｐａｄｇｅｍ媒介相互作用の阻害方法
CA2109527A1 (en) * 1991-05-03 1992-11-04 Elaine Tuomanen Amino-acid sequence homologies between selectins and b pertussis toxin-peptides derived therefrom, antibodies thereto and pharmaceutical compositions
US5374655A (en) * 1991-06-10 1994-12-20 Alberta Research Council Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures
EP0631501B1 (de) * 1992-03-20 2000-08-30 Cor Therapeutics, Inc. Durch glykosylierung vermittelte hemmung des faktors x
US5440015A (en) * 1992-07-21 1995-08-08 Glycomed Incorporated Selectin peptide medicaments for treating disease
US5453272A (en) * 1992-10-02 1995-09-26 Alberta Research Council Lectin derived carbohydrate binding-peptide
ATE210452T1 (de) * 1992-10-02 2001-12-15 Alberta Res Council Entzündungshemmende tolerogene und immunoinhibitorische eigenschaften von karbohydrate bindende peptide
US5496934A (en) * 1993-04-14 1996-03-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acids encoding a cellulose binding domain
US5856122A (en) * 1993-08-24 1999-01-05 University Of Alberta Modification of pertussis toxin
US5858965A (en) * 1994-12-04 1999-01-12 Yeda Research And Development Co. Ltd. Pharmaceutical compositions for the treatment of autoimmune diseases comprising the B-oligomer of pertussis toxin or its subunits
IL111866A (en) * 1994-12-04 2005-03-20 Yeda Res & Dev Pharmaceutical compositions comprising the b-oligomer of pertussis toxin

Also Published As

Publication number Publication date
WO1994007517A1 (en) 1994-04-14
US20020054880A1 (en) 2002-05-09
JPH08501569A (ja) 1996-02-20
US5736143A (en) 1998-04-07
US5833990A (en) 1998-11-10
DE69331331D1 (de) 2002-01-24
EP0666758A1 (de) 1995-08-16
CA2145881C (en) 2000-12-19
ES2169724T3 (es) 2002-07-16
CA2145881A1 (en) 1994-04-14
AU686116B2 (en) 1998-02-05
EP0666758B1 (de) 2001-12-12
AU5105693A (en) 1994-04-26
DE69331331T2 (de) 2002-08-14
US5747040A (en) 1998-05-05
US6245883B1 (en) 2001-06-12

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Legal Events

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UEP Publication of translation of european patent specification
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