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ATE203546T1 - Lagerstabile hämoglobinlösungen - Google Patents

Lagerstabile hämoglobinlösungen

Info

Publication number
ATE203546T1
ATE203546T1 AT96920119T AT96920119T ATE203546T1 AT E203546 T1 ATE203546 T1 AT E203546T1 AT 96920119 T AT96920119 T AT 96920119T AT 96920119 T AT96920119 T AT 96920119T AT E203546 T1 ATE203546 T1 AT E203546T1
Authority
AT
Austria
Prior art keywords
stable hemoglobin
hemoglobin solutions
storage
solutions
storage stable
Prior art date
Application number
AT96920119T
Other languages
English (en)
Inventor
Bruce A Kerwin
Douglas L Looker
Original Assignee
Baxter Biotech Tech Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Biotech Tech Sarl filed Critical Baxter Biotech Tech Sarl
Application granted granted Critical
Publication of ATE203546T1 publication Critical patent/ATE203546T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT96920119T 1995-05-02 1996-05-01 Lagerstabile hämoglobinlösungen ATE203546T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/433,896 US5929031A (en) 1995-05-02 1995-05-02 Storage stable hemoglobin solutions
PCT/US1996/006080 WO1996034889A1 (en) 1995-05-02 1996-05-01 Storage stable hemoglobin solutions

Publications (1)

Publication Number Publication Date
ATE203546T1 true ATE203546T1 (de) 2001-08-15

Family

ID=23721974

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96920119T ATE203546T1 (de) 1995-05-02 1996-05-01 Lagerstabile hämoglobinlösungen

Country Status (7)

Country Link
US (1) US5929031A (de)
EP (1) EP0826004B1 (de)
JP (1) JPH11507016A (de)
AT (1) ATE203546T1 (de)
CA (1) CA2216382A1 (de)
DE (1) DE69614105T2 (de)
WO (1) WO1996034889A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6964798B2 (en) 1993-11-16 2005-11-15 Baxter International Inc. Multi-layered polymer based thin film structure for medical grade products
US6242417B1 (en) * 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US6288027B1 (en) 1995-03-23 2001-09-11 Biopure Corporation Preserving a hemoglobin blood substitute with a transparent overwrap
US6271351B1 (en) 1995-03-23 2001-08-07 Biopure Corporation Method for preserving a hemoglobin blood substitute
US6610832B1 (en) 1995-03-23 2003-08-26 Biopure Corporation Preserving a hemoglobin blood substitute with a transparent overwrap
US5981710A (en) * 1997-07-21 1999-11-09 Baxter International, Inc. Therapeutic hemoglobin composition having isotropically increased size
US6018035A (en) * 1997-07-21 2000-01-25 Baxter International Inc. Reagents for isotropic size enhancement of a peptide, protein, nucleotide or other substrate
US6204254B1 (en) 1997-09-12 2001-03-20 Baxter International, Inc. Biocompatible surfaces and a method for their preparation
JP5410647B2 (ja) * 1999-07-01 2014-02-05 シスメックス株式会社 グリコヘモグロビン分析装置用の標準物質及びコントロール物質
JP3466516B2 (ja) 1999-09-07 2003-11-10 科学技術振興事業団 安定保存可能な酸素輸液剤
US6894150B1 (en) 1999-10-01 2005-05-17 Ross Walden Tye Non-pyrogenic, endotoxin-free, stroma-free tetrameric hemoglobin
US6949384B2 (en) * 2001-12-21 2005-09-27 Spectromedical Inc. Method for monitoring degradation of Hb-based blood substitutes
US7449339B2 (en) * 1999-11-23 2008-11-11 Nir Diagnostics Inc. Spectroscopic method and apparatus for total hemoglobin measurement
FR2809624B1 (fr) * 2000-05-31 2002-08-02 Centre Nat Rech Scient Utilisation comme substitut sanguin d'une hemoglobine extracellulaire de poids moleculaire eleve
US6974447B2 (en) * 2001-04-17 2005-12-13 Baxter International Inc. High gas barrier receptacle and closure assembly
JP2004538264A (ja) * 2001-04-18 2004-12-24 ノースフィールド ラボラトリーズ 安定化ヘモグロビン溶液の保管のための可撓性容器システム
CA2474134C (en) * 2002-01-15 2015-11-17 Board Of Regents, The University Of Texas System Methods and compositions to reduce scattering of light during therapeutic and diagnostic imaging procedures
US7635463B2 (en) * 2002-02-27 2009-12-22 Pharmain Corporation Compositions for delivery of therapeutics and other materials
US20050260259A1 (en) * 2004-04-23 2005-11-24 Bolotin Elijah M Compositions for treatment with glucagon-like peptide, and methods of making and using the same
US7138105B2 (en) * 2002-02-27 2006-11-21 Pharmain Compositions for delivery of therapeutics and other materials, and methods of making and using the same
CN1703233A (zh) * 2002-07-12 2005-11-30 米德列斯公司 防止蛋白氧化降解的方法和组合物
US7223604B1 (en) * 2002-09-27 2007-05-29 Science & Technology Corporation @ Unm Methods and kits for the detection of erythrocytes
JP2006516994A (ja) * 2003-01-29 2006-07-13 ノースフィールド ラボラトリーズ、インコーポレイテッド テトラマーの量を低下させた重合ヘモグロビン溶液及び調製するための方法
MXPA06011837A (es) 2004-04-27 2007-01-16 Baxter Int Sistema de reactor de tanque agitado.
JP2006164312A (ja) * 2004-12-02 2006-06-22 Hitachi Ltd 半導体装置およびそれを用いた磁気記録再生装置
AU2006220548B2 (en) * 2005-03-07 2011-04-21 Sangart, Inc. Composition and methods for delivering carbon monoxide (CO) and nitric ozide (NO) CO to tissue using heme proteins as carriers
WO2007087570A2 (en) 2006-01-24 2007-08-02 Northfield Laboratories, Inc. Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
US7504377B2 (en) * 2006-10-23 2009-03-17 Ikor, Inc. Nitric oxide-blocked cross-linked tetrameric hemoglobin
US7494974B2 (en) * 2006-10-24 2009-02-24 Ikor, Inc. Carboxymethylated cross-linked tetrameric hemoglobin
JP2008195656A (ja) * 2007-02-14 2008-08-28 Nipro Corp 人工酸素運搬体製剤
US8609815B2 (en) 2010-09-02 2013-12-17 Sangart, Inc. Methods for preparing stable deoxygenated PEG-hemoglobin conjugate solutions comprising an antioxidant
WO2012094671A2 (en) * 2011-01-07 2012-07-12 Somerset Group Enterprises, Inc. Modular extracorporeal systems and methods for treating blood-borne diseases
WO2013106443A1 (en) 2012-01-09 2013-07-18 Somerset Group Enterprises, Inc. Modular extracorporeal systems and methods for treating blood-borne diseases
US9763889B2 (en) * 2015-06-29 2017-09-19 Billion King International Ltd. Oral delivery system for hemoglobin based oxygen carriers
US10052290B2 (en) * 2016-02-04 2018-08-21 Billion King International Ltd. Enteric-coated hemoglobin multiparticulate for oral delivery of hemoglobin based oxygen carriers
EP4133285A1 (de) * 2020-04-09 2023-02-15 Institut National de la Santé et de la Recherche Médicale (INSERM) Verfahren und zusammensetzungen zur bestimmung der qualität von einheiten roter blutkörperchen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3144705C2 (de) * 1981-11-11 1983-12-08 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines lagerstabilen, vernetzten Hämoglobinpräparates mit hoher Sauerstoff-Transportkapazität, sowie das nach diesem Verfahren hergestellte Hämoglobinpräparat
US4727027A (en) * 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4861867A (en) * 1988-02-03 1989-08-29 Baxter International, Inc. Purified hemoglobin solutions and method for making same
US5234903A (en) * 1989-11-22 1993-08-10 Enzon, Inc. Chemically modified hemoglobin as an effective, stable non-immunogenic red blood cell substitute
WO1992002239A1 (en) * 1990-08-06 1992-02-20 Baxter International Inc. Stable hemoglobin based composition and method to store same
US5352773A (en) * 1990-08-06 1994-10-04 Baxter International Inc. Stable hemoglobin based composition and method to store same
AU9067791A (en) * 1990-11-20 1992-06-11 Enzon, Inc. Method of enhancing long-term storage stability of hemoglobin products
SE9301581D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Protein formulation

Also Published As

Publication number Publication date
AU5852096A (en) 1996-11-21
US5929031A (en) 1999-07-27
WO1996034889A1 (en) 1996-11-07
DE69614105T2 (de) 2002-03-21
JPH11507016A (ja) 1999-06-22
EP0826004B1 (de) 2001-07-25
CA2216382A1 (en) 1996-11-07
AU708264B2 (en) 1999-07-29
EP0826004A1 (de) 1998-03-04
DE69614105D1 (de) 2001-08-30

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties