[go: up one dir, main page]

ATE198982T1 - Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen - Google Patents

Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen

Info

Publication number
ATE198982T1
ATE198982T1 AT95934711T AT95934711T ATE198982T1 AT E198982 T1 ATE198982 T1 AT E198982T1 AT 95934711 T AT95934711 T AT 95934711T AT 95934711 T AT95934711 T AT 95934711T AT E198982 T1 ATE198982 T1 AT E198982T1
Authority
AT
Austria
Prior art keywords
pct
active substance
dosage forms
pharmaceutically active
pharmaceutical dosage
Prior art date
Application number
AT95934711T
Other languages
English (en)
Inventor
Richard John Yarwood
Patrick Kearney
Andrew Roy Thompson
Original Assignee
Scherer Technologies Inc R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Inc R P filed Critical Scherer Technologies Inc R P
Application granted granted Critical
Publication of ATE198982T1 publication Critical patent/ATE198982T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95934711T 1994-10-28 1995-10-20 Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen ATE198982T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9421836A GB9421836D0 (en) 1994-10-28 1994-10-28 Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
PCT/GB1995/002485 WO1996013251A1 (en) 1994-10-28 1995-10-20 Process for preparing solid pharmaceutical dosage forms of hydrophobic substances

Publications (1)

Publication Number Publication Date
ATE198982T1 true ATE198982T1 (de) 2001-02-15

Family

ID=10763606

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95934711T ATE198982T1 (de) 1994-10-28 1995-10-20 Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen

Country Status (16)

Country Link
US (1) US5827541A (de)
EP (1) EP0737064B1 (de)
JP (1) JPH09511255A (de)
KR (1) KR100352881B1 (de)
CN (1) CN1236762C (de)
AT (1) ATE198982T1 (de)
AU (1) AU3702795A (de)
DE (1) DE69520036T2 (de)
DK (1) DK0737064T3 (de)
ES (1) ES2154737T3 (de)
GB (1) GB9421836D0 (de)
GR (1) GR3035427T3 (de)
MX (1) MX9602515A (de)
PL (1) PL187254B1 (de)
PT (1) PT737064E (de)
WO (1) WO1996013251A1 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9517062D0 (en) 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
GB9702799D0 (en) * 1997-02-12 1997-04-02 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms
US6277458B1 (en) * 1999-03-15 2001-08-21 The Procter & Gamble Company Release strip with partible break to facilitate
US5976577A (en) * 1997-07-11 1999-11-02 Rp Scherer Corporation Process for preparing fast dispersing solid oral dosage form
US6852337B2 (en) 1998-04-09 2005-02-08 Roche Diagnostics Gmbh Carvedilol-galenics
US20040013613A1 (en) * 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
US8236352B2 (en) 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
CZ20011739A3 (cs) * 1998-11-20 2001-10-17 Rtp Pharma Inc. Dispergovatelné fosfolipidem stabilizované mikročástice
GT200100039A (es) * 2000-03-16 2001-12-31 Pfizer Inhibidor de la glucogeno fosforilasa.
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
KR20030024849A (ko) * 2000-08-10 2003-03-26 델시스 파머수티컬 코포레이션 소수성 약물의 개선된 고형 약제학적 투여 제제
US6814978B2 (en) 2000-12-29 2004-11-09 Mcneil-Ppc, Inc. Process for preparing a soft tablet
SI1353696T1 (sl) 2001-01-26 2007-04-30 Schering Corp Kombinacije aktivatorja(-ev) peroksisomskega proliferatorja aktivirajocega receptorja (PPAR) in inhibitorja(-ev) absorpcije sterola in oblike zdravljenja za vaskularne indikacije
AR035533A1 (es) 2001-01-26 2004-06-02 Schering Corp Uso de por lo menos un inhibidor de la absorcion de los esteroles o sus sales, solvatos, prodrogas farmaceuticamente aceptables o mezclas de los mismos para la preparacion de un medicamento para el tratamiento de la sitosterolemia, composiciones farmaceuticas, el uso de dichas composiciones para la
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
WO2002072150A2 (en) 2001-03-13 2002-09-19 Angiotech Pharmaceuticals Inc. Micellar drug delivery vehicles and uses thereof
US20030157170A1 (en) * 2001-03-13 2003-08-21 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
PT1392254E (pt) * 2001-04-20 2007-06-29 Univ British Columbia Sistemas de distribuição micelares de fármacos para fármacos hidrofóbicos.
RU2004107501A (ru) * 2001-08-14 2005-02-20 Байотай Терапис Корпорейшн (Fi) Способ лечения алкоголизма или злоупотребления алкоголем
JP2005504091A (ja) 2001-09-21 2005-02-10 シェーリング コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
WO2003030872A2 (en) * 2001-10-12 2003-04-17 Elan Pharma International Ltd. Compositions having a combination of particles for immediate release and for controlled release
EP1941878A1 (de) 2002-01-10 2008-07-09 Biovail Laboratories International Srl Sedative Formulierungen ohne Benzodiazepin
KR20040079967A (ko) * 2002-02-01 2004-09-16 화이자 프로덕츠 인크. 고체 약물 분산액을 함유하는 속방형 제형
US20030215502A1 (en) * 2002-03-20 2003-11-20 Elan Pharma International Limited Fast dissolving dosage forms having reduced friability
WO2004000223A2 (en) * 2002-06-20 2003-12-31 Orapharma, Inc. Rapidly disintegrating formulations for treating or preventing mucositis
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
FR2845914B1 (fr) * 2002-10-18 2005-11-04 Schwarz Pharma Lab Compose antiemetique a desagregation rapide
JP2006508189A (ja) 2002-11-06 2006-03-09 シェーリング コーポレイション 自己免疫障害の処置のためのコレステロール吸収インヒビター
ATE514418T1 (de) * 2002-11-12 2011-07-15 Elan Pharma Int Ltd Rasch zerfallende feste darreichungsformen mit nichtbröseliger konsistenz und pullulan
ATE406364T1 (de) 2003-03-07 2008-09-15 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
CN1756755A (zh) * 2003-03-07 2006-04-05 先灵公司 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US7208486B2 (en) 2003-03-07 2007-04-24 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US20040224024A1 (en) * 2003-04-23 2004-11-11 Massachusetts Institute Of Technology Controlled drug release formulations containing polyion complexes
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
EP2322198A2 (de) 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Pharmazeutische Zusammensetzungen mit niedrigen Dosen von Desmopressin
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
EP1586313A1 (de) * 2004-04-07 2005-10-19 The Jordanian Pharmaceutical Manufacturing Co. Ltd. Metoclopramid enthaltende pharmazeutische Zubereitungen und Herstellungsmethode
US7345178B2 (en) 2005-08-04 2008-03-18 Sirtris Pharmaceuticals, Inc. Sirtuin modulating compounds
BRPI0620578A2 (pt) * 2005-12-27 2011-12-06 Jubilant Organosys Ltd composição farmacêutica que dissolve na boca e processo para o preparo da mesma
US20070243248A1 (en) * 2006-04-14 2007-10-18 Cherukuri S Rao Rapidly disintegrating solid oral dosage form of liquid dispersions
CN101431895A (zh) * 2006-05-01 2009-05-13 卡普里康制药公司 新颖的曲坦制剂和制备它们的方法
TW200817049A (en) * 2006-06-05 2008-04-16 Verus Pharmaceuticals Inc Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
US20070293581A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Methods for Buccal, Lingual or Sublingual Dosing Regimens of Epinephrine for the Treatment of Allergic Emergencies
WO2007147133A1 (en) * 2006-06-15 2007-12-21 Serenex, Inc. Stabilized tetracycline compositions
FR2909877B1 (fr) * 2006-12-13 2009-07-10 Galenix Dev Soc Par Actions Si Composition pharmaceutique contenat de la 5-chloro-1-[1-[3- (2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)propyl] piperidin-4-yl]-1,3-dihydro-2h-benzimidazol-2-one et son procede de preparation
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
WO2011026080A1 (en) 2009-08-31 2011-03-03 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam, processes for preparation, and use to treat arthritis and/or pain
EP2359812A1 (de) 2010-01-18 2011-08-24 Cephalon France Lyophilisierte orale Zusammensetzungen
TR201002084A1 (tr) 2010-03-19 2011-10-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Oral yolla dağılan donepezil tablet formülasyonları ve hazırlama yöntemi
EP2377522B1 (de) 2010-04-15 2013-01-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Formulierungen von im Mund zerfallenden Mirtazapintabletten und Herstellungsverfahren dafür.
EP2611781A1 (de) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Schnelllösliche darreichungsformen von 5-ht2c-agonisten
EP2609911A1 (de) 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. Neuartiges Verfahren zur Herstellung von oral zerfallenden Flurbiprofen-Formulierungen
US8431155B1 (en) 2012-04-30 2013-04-30 Veroscience Llc Bromocriptine formulations
FR2997766B1 (fr) * 2012-11-08 2015-06-12 Alain Iltis Systeme et procede de detection de rayonnement gamma de type gamma camera
WO2016042372A1 (en) 2014-09-17 2016-03-24 Steer Engineering Private Limited Effervescent composition and method of making it
US11219594B2 (en) 2015-12-12 2022-01-11 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
CN105663055B (zh) * 2016-03-01 2018-07-06 山东司邦得制药有限公司 一种小儿多潘立酮干混悬剂及其制备方法
CN105560199B (zh) * 2016-03-01 2018-07-06 山东司邦得制药有限公司 一种小儿多潘立酮口崩片及其制备方法
ES2980126T3 (es) 2016-12-31 2024-09-30 Bioxcel Therapeutics Inc Uso de dexmedetomidina para el tratamiento de la agitación
CZ307916B6 (cs) 2017-05-08 2019-08-21 mcePharma s. r. o. Orodispergovatelná tableta s biodostupným kurkuminem a její použití
JP7488201B2 (ja) 2018-06-27 2024-05-21 バイオエクセル セラピューティクス,インコーポレイテッド デクスメデトミジンを含むフィルム製剤、及びその作製方法
MX2022000709A (es) 2019-07-19 2022-05-19 Bioxcel Therapeutics Inc Regimenes de tratamiento con dexmedetomidina no sedante.
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
GB2111423B (en) * 1981-12-02 1985-06-26 Wyeth John & Brother Ltd Making quick-dissolving pills
EP0081921A1 (de) * 1981-12-10 1983-06-22 Hawker Siddeley Revenue Controls Limited Kreditkartenverfahren
FR2561916B1 (fr) * 1984-03-30 1987-12-11 Lafon Labor Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5039540A (en) * 1989-08-14 1991-08-13 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
FR2661610B1 (fr) * 1990-05-02 1994-09-30 Rhone Poulenc Sante Nouvelle forme lyophilisee de la diosmine et sa preparation.
WO1992017209A1 (en) * 1991-04-08 1992-10-15 Sumitomo Pharmaceuticals Company, Limited Porous solid preparation containing physiologically active protein substance
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
TW272942B (de) * 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
PL187254B1 (pl) 2004-06-30
CN1140408A (zh) 1997-01-15
GR3035427T3 (en) 2001-05-31
EP0737064A1 (de) 1996-10-16
AU3702795A (en) 1996-05-23
US5827541A (en) 1998-10-27
PT737064E (pt) 2001-05-31
WO1996013251A1 (en) 1996-05-09
PL315181A1 (en) 1996-10-14
ES2154737T3 (es) 2001-04-16
MX9602515A (es) 1997-05-31
DE69520036T2 (de) 2001-06-21
CN1236762C (zh) 2006-01-18
GB9421836D0 (en) 1994-12-14
EP0737064B1 (de) 2001-01-31
DE69520036D1 (de) 2001-03-08
DK0737064T3 (da) 2001-02-26
JPH09511255A (ja) 1997-11-11
KR100352881B1 (ko) 2003-01-06

Similar Documents

Publication Publication Date Title
ATE198982T1 (de) Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen
ATE198150T1 (de) Verfahren zur herstellung fester pharmazeutischer dosierungsform
DE69521406D1 (de) Apparat und verfahren zur herstellung fester formen mit gesteuerter freisetzung des wirkstoffs
ATE204162T1 (de) Verfahren zur herstellung von wirkstoffzubereitungen in form einer festen lösung des wirkstoffs in einer polymermatrix
ATE204469T1 (de) Verfahren zur herstellung von morphologisch einheitlichen mikrokapseln sowie nach diesem verfahren hergestellte mikrokapseln
DE69429048D1 (de) Biologisch erodierbare Vorrichtung zur Verabreichung von Wirkstoffen
HUT63954A (en) Process for producing active ingredient containing microparticldes from hydrolytically degredable polymers
ATE375145T1 (de) Induziertes phasenübergangs verfahren zur herstellung von hydrophile wirkstoffe enthaltende mikropartikeln
DE69840495D1 (de) Darreichungsform, welche rasche dispersionseigenschaften entfaltet, anwendungsverfahren sowie verfahren zur herstellung derselben
DE69833375D1 (de) Implantate zur gesteuerten freisetzung von pharmazeutischen wirkstoffen und verfahren zur herstellung
ATE219664T1 (de) Verfahren zur herstellung fester pharmazeutischer dosisformen
ATE221772T1 (de) Verfahren und apparat zur herstellung von schnelllöslichen dosierungseinheiten und daraus erhältliches produkt
DE69104365D1 (de) Vaterit und verfahren zu dessen herstellung.
DE69922017D1 (de) Arzneimittel und verfahren zur behandlung von intrazellulären infektionen
ATE246515T1 (de) Verfahren zur herstellung von oralen dosierungsformulierungen enthaltend diclofenac
DE59611383D1 (de) Darreichungsform zur applikation von pharmazeutischen wirkstoffen und hilfsstoffen und verfahren zur herstellung derselben
GR3032071T3 (en) Process for producing active substances from unused or discarded devices for the transdermal administration of active substances and/or from their production waste
ATE288901T1 (de) Verfahren zur herstellung von 5-hydroxymethyl-2- oxazolidinon und neues zwischenprodukt
DE69813550D1 (de) Vorrichtung und verfahren zur herstellung von radioaktiven arzneimitteln zur verabreichung
ATE126285T1 (de) Verfahren und vorrichtung zur nassbehandlung von textilmaterialien sowie zur wiedereinstellung eines behandlungsbades.
ATE66468T1 (de) Leukotrienantagonisten, verfahren zu ihrer herstellung und ihre anwendung zur behandlung von krankheiten.
UA9522A (uk) Спосіб лікування аутоімунного тиреоідиту