ATE193207T1 - Vorbeugung von verletzungen und degenerationen von photorezeptoren durch neurotrophische faktoren - Google Patents

Vorbeugung von verletzungen und degenerationen von photorezeptoren durch neurotrophische faktoren

Info

Publication number: ATE193207T1
Authority: AT; Austria
Prior art keywords: degeneration; injury; prevention; photoreceptors; neurotrophic factors
Prior art date: 1992-02-14

Application number

AT93905054T

Other languages

English (en)

Inventor

Matthew M Lavail

Roy H Steinberg

George D Yancopolous

Original Assignee

Regeneron Pharma

Univ California

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-14

Filing date

1993-02-12

Publication date

2000-06-15

1993-02-12 Application filed by Regeneron Pharma, Univ California filed Critical Regeneron Pharma

2000-06-15 Application granted granted Critical

2000-06-15 Publication of ATE193207T1 publication Critical patent/ATE193207T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2006—IL-1
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2093—Leukaemia inhibitory factor [LIF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Dermatology (AREA)
Psychology (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Control Of Combustion (AREA)
Electrotherapy Devices (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

AT93905054T 1992-02-14 1993-02-12 Vorbeugung von verletzungen und degenerationen von photorezeptoren durch neurotrophische faktoren ATE193207T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US83609092A	1992-02-14	1992-02-14
US89730792A	1992-06-11	1992-06-11
PCT/US1993/001328 WO1993015608A1 (en)	1992-02-14	1993-02-12	Prevention of retinal injury and degeneration by specific factors

Publications (1)

Publication Number	Publication Date
ATE193207T1 true ATE193207T1 (de)	2000-06-15

Family

ID=27125846

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93905054T ATE193207T1 (de)	1992-02-14	1993-02-12	Vorbeugung von verletzungen und degenerationen von photorezeptoren durch neurotrophische faktoren

Country Status (9)

Country	Link
EP (1)	EP0671879B1 (de)
JP (1)	JP3645902B2 (de)
CN (1)	CN1077799C (de)
AT (1)	ATE193207T1 (de)
AU (1)	AU677951B2 (de)
CA (1)	CA2130115C (de)
DE (1)	DE69328730T2 (de)
IL (1)	IL104726A (de)
WO (1)	WO1993015608A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5166317A (en) *	1988-10-31	1992-11-24	Houston Biotechnology Incorporated	Neurotrophic factor
US6780837B1 (en)	1989-08-30	2004-08-24	The Regents Of The University Of California	Prevention of retinal injury and degeneration by specific factors
GB9203533D0 (en) *	1992-02-19	1992-04-08	Erba Carlo Spa	Use of the conjugate between a fibroblast growth factor and a saporin in treating ocular pathologies
JP4098355B2 (ja) *	1993-08-12	2008-06-11	ニューロテックユーエスエー，インコーポレイテッド	遺伝的に改変された細胞を含む生体適合性免疫隔離カプセル
US6750196B1 (en)	1995-03-27	2004-06-15	Acorda Therapeutics	Methods of treating disorders of the eye
US5641750A (en) *	1995-11-29	1997-06-24	Amgen Inc.	Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product
US5641749A (en) *	1995-11-29	1997-06-24	Amgen Inc.	Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product
BR9712824A (pt) *	1996-09-13	1999-12-21	Advanced Medicine Research Ins	Composição oftálmica de fator neurotrófico, agente de tratamento de desordem funcional do nervo ótico e método para tratamento de desordem funcional do nervo ótico
DE19718826A1 (de) *	1997-05-05	1998-11-12	Marion S Dr Eckmiller	Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung
AU4994000A (en) *	1999-05-06	2000-11-21	Schepens Eye Research Institute, Inc., The	Low-dose il-1beta-induced photoreceptor cell rescue without retinal dysplasia
CN113069533A (zh) *	2021-03-08	2021-07-06	温州医科大学	一种长效成纤维细胞生长因子凝胶

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ233071A (en) *	1989-03-30	1993-02-25	Sumitomo Pharma	Neurotrophic peptides, extraction from mammalian hippocampal tissue and pharmaceutical compositions thereof
US5260059A (en) *	1989-04-14	1993-11-09	The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University	Treatment of open-angle glaucoma by modulation matrix metalloproteinases and their inhibitor
US5229500A (en) *	1989-08-30	1993-07-20	Regeneron Pharmaceuticals, Inc.	Brain derived neurotrophic factor

1993
- 1993-02-12 AU AU36194/93A patent/AU677951B2/en not_active Expired
- 1993-02-12 EP EP93905054A patent/EP0671879B1/de not_active Expired - Lifetime
- 1993-02-12 WO PCT/US1993/001328 patent/WO1993015608A1/en active IP Right Grant
- 1993-02-12 AT AT93905054T patent/ATE193207T1/de not_active IP Right Cessation
- 1993-02-12 JP JP51432493A patent/JP3645902B2/ja not_active Expired - Lifetime
- 1993-02-12 CA CA002130115A patent/CA2130115C/en not_active Expired - Lifetime
- 1993-02-12 DE DE69328730T patent/DE69328730T2/de not_active Expired - Lifetime
- 1993-02-13 CN CN93103084A patent/CN1077799C/zh not_active Expired - Lifetime
- 1993-02-14 IL IL10472693A patent/IL104726A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2130115C (en)	2004-09-14
DE69328730D1 (de)	2000-06-29
JP3645902B2 (ja)	2005-05-11
CN1080188A (zh)	1994-01-05
IL104726A0 (en)	1993-06-10
CN1077799C (zh)	2002-01-16
CA2130115A1 (en)	1993-08-19
IL104726A (en)	2000-07-26
EP0671879B1 (de)	2000-05-24
AU677951B2 (en)	1997-05-15
AU3619493A (en)	1993-09-03
EP0671879A1 (de)	1995-09-20
HK1008292A1 (en)	1999-05-07
EP0671879A4 (de)	1996-01-17
WO1993015608A1 (en)	1993-08-19
JPH07507053A (ja)	1995-08-03
DE69328730T2 (de)	2000-09-28

Publication	Publication Date	Title
ATE193207T1 (de)	2000-06-15	Vorbeugung von verletzungen und degenerationen von photorezeptoren durch neurotrophische faktoren
ATE190496T1 (de)	2000-04-15	Behandlung von autoimmunkrankheiten durch verabreichung von autoantigenen in form von aerosol
MX9204381A (es)	1993-02-01	Metodo para tratar inflamacion ocular
DK0548208T3 (da)	1997-04-21	Fremgangsmåde til behandling af øjenlidelser ved nedsættelse af niveauet af 12(R)-hydrocyeicosatetraensyre og 12(R)-dihydroxyeicosatriensyre
DE122006000010I2 (de)	2007-10-04	Benzocyclobutyl- oder Indanyl-Alkyl-Amino-Alkyl substituierte 3-Benzazepin-2-ones, verwendbar in derBehandlung von kardiovaskularen Krankheiten
DE69231062D1 (de)	2000-06-21	Morphogen-induzierte Modulation von entzündlichen Antworten
DK447788D0 (da)	1988-08-10	Apparat til applikation af implantater
ATE198708T1 (de)	2001-02-15	Verwendung von makrolid-verbindungen gegen augenerkrankungen
ATE319474T1 (de)	2006-03-15	Behandlung von autoimmunkrankheiten durch orale verabreichung von autoantigenen
ATE140388T1 (de)	1996-08-15	Zusammensetzungen enthaltend omega conotoxin peptide derivate und deren verwendung zur behandlung von ischämie-artigen neuronalen schädigungen
DK549189A (da)	1990-01-03	Galanthamin-analoge samt anvendelse af disse til fremstilling af laegemidler til behandling af alzheimer's syge
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DK230590A (da)	1990-11-16	Sproejte til brug ved kataraktkirurgi
FR2343267A1 (fr)	1977-09-30	Filtre de protection contre les rayonnements, notamment pour la pigmentation directe par exposition au soleil
DK0413329T3 (da)	1997-08-18	5-methyl-isoxazol-4-carboxylsyreanilider og 2-hydroxyethyliden-cyaneddikesyreanilider til behandling af øjensygdomme
Hudson et al.	1980	Internal desynchronization between two identified circadian oscillators in Aplysia.
LV10689A (lv)	1995-06-20	Dimetilpolisiloksana pielietojums kunga un zarnu trakta slimibu arstesanai
Crozier et al.	1937	Photic stimulation of young rats
ATE59778T1 (de)	1991-01-15	Verwendung von sulfonamidderivaten zur herstellung eines antivirusmittels.
ATE82850T1 (de)	1992-12-15	Verwendung von 2-pyrimidinyl-1-piperazinderivaten.
ATE70181T1 (de)	1991-12-15	Verwendung von oxochinazolinderivaten bei der behandlung von hyperurikaemie.
FI905952A7 (fi)	1990-12-03	Menetelmä ja keinot silmän pupillin supistumisen aiheuttamiseksi tai e stämiseksi
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Anderson	1966	Prior shock trauma and test-shock intensity as determinants of escape learning
SE8303729D0 (sv)	1983-06-29	Terapeutiskt medel for behandling av allergiska sjukdomstillstand, immunkomplexsjukdomar och tumorer

Legal Events

Date	Code	Title	Description
2000-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties