ATE187437T1 - Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide - Google Patents

Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide

Info

Publication number: ATE187437T1
Authority: AT; Austria
Prior art keywords: hydroxy; triiodo; oxopropyl; crystallization; bis
Prior art date: 1995-09-08

Application number

AT96928403T

Other languages

English (en)

Inventor

Marina Mauro

Original Assignee

Bracco Int Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-08

Filing date

1996-08-02

Publication date

1999-12-15

1995-09-08 Priority claimed from ITRM950599 external-priority patent/IT1277934B1/it

1995-12-19 Priority claimed from ITRM950831 external-priority patent/IT1277950B1/it

1996-08-02 Application filed by Bracco Int Bv filed Critical Bracco Int Bv

1999-12-15 Application granted granted Critical

1999-12-15 Publication of ATE187437T1 publication Critical patent/ATE187437T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT96928403T 1995-09-08 1996-08-02 Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide ATE187437T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITRM950599 IT1277934B1 (it)	1995-09-08	1995-09-08	Processo per la cristallizzazione da acqua della s-n,n' -bis- ( 2-idrossi -1 -(idrossimetil) etil) -5- ((2 -idrossi -1- ossopropil)
ITRM950831 IT1277950B1 (it)	1995-12-19	1995-12-19	Processo per la cristallizzazione da acqua della s-n,n'-bis (2-idrossi -1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino).2,4,6-

Publications (1)

Publication Number	Publication Date
ATE187437T1 true ATE187437T1 (de)	1999-12-15

Family

ID=26332086

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96928403T ATE187437T1 (de)	1995-09-08	1996-08-02	Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide

Country Status (17)

Country	Link
US (1)	US5689002A (de)
EP (1)	EP0790979B1 (de)
JP (1)	JP4070235B2 (de)
KR (1)	KR100270411B1 (de)
CN (1)	CN1070843C (de)
AT (1)	ATE187437T1 (de)
AU (1)	AU708195B2 (de)
BR (1)	BR9606624A (de)
CA (1)	CA2204734C (de)
CZ (1)	CZ288645B6 (de)
DE (1)	DE69605528T2 (de)
ES (1)	ES2140887T3 (de)
HK (1)	HK1001861A1 (de)
HU (1)	HU220965B1 (de)
NO (1)	NO308841B1 (de)
PL (1)	PL184937B1 (de)
WO (1)	WO1997009300A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT101720A (pt) *	1995-06-08	1997-01-31	Hovione Sociedade Quimica S A	Processo para a purificacao e cristalizacao de iopamidol
KR20000031642A (ko) *	1998-11-09	2000-06-05	강재헌	이오파미돌의 결정화 방법
WO2003042215A1 (en)	2001-11-16	2003-05-22	Ranbaxy Laboratories Limited	Process for the preparation of crystalline imipenem
CN100418945C (zh) *	2006-01-13	2008-09-17	江苏省原子医学研究所	一种碘昔兰的纯化方法
US20110021834A1 (en) *	2009-07-21	2011-01-27	Ge Healthcare As	Continuous process of preparing intermediate for non-ionic x-ray contrast agents
WO2012136813A2 (en)	2011-04-07	2012-10-11	Universitetet I Oslo	Agents for medical radar diagnosis
WO2018104228A1 (en)	2016-12-05	2018-06-14	Bracco Imaging Spa	Mechanochemical synthesis of radiographic agents intermediates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH608189A5 (de) *	1974-12-13	1978-12-29	Savac Ag
IL110391A (en) *	1993-07-30	1998-12-06	Zambon Spa	Process for the formation of infamidol

1996
- 1996-08-02 JP JP50604597A patent/JP4070235B2/ja not_active Expired - Lifetime
- 1996-08-02 DE DE69605528T patent/DE69605528T2/de not_active Expired - Lifetime
- 1996-08-02 AU AU67888/96A patent/AU708195B2/en not_active Expired
- 1996-08-02 KR KR1019970702994A patent/KR100270411B1/ko not_active IP Right Cessation
- 1996-08-02 PL PL96320027A patent/PL184937B1/pl unknown
- 1996-08-02 CZ CZ19971385A patent/CZ288645B6/cs not_active IP Right Cessation
- 1996-08-02 WO PCT/EP1996/003399 patent/WO1997009300A1/en active IP Right Grant
- 1996-08-02 AT AT96928403T patent/ATE187437T1/de not_active IP Right Cessation
- 1996-08-02 CN CN96191028A patent/CN1070843C/zh not_active Expired - Lifetime
- 1996-08-02 ES ES96928403T patent/ES2140887T3/es not_active Expired - Lifetime
- 1996-08-02 HU HU9801837A patent/HU220965B1/hu unknown
- 1996-08-02 BR BR9606624A patent/BR9606624A/pt not_active Application Discontinuation
- 1996-08-02 CA CA002204734A patent/CA2204734C/en not_active Expired - Lifetime
- 1996-08-02 EP EP96928403A patent/EP0790979B1/de not_active Expired - Lifetime
- 1996-09-05 US US08/708,668 patent/US5689002A/en not_active Expired - Lifetime
1997
- 1997-04-23 NO NO971863A patent/NO308841B1/no not_active IP Right Cessation
1998
- 1998-02-10 HK HK98100990A patent/HK1001861A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
BR9606624A (pt)	1997-11-11
JP4070235B2 (ja)	2008-04-02
KR970707073A (ko)	1997-12-01
AU708195B2 (en)	1999-07-29
CZ138597A3 (cs)	1998-02-18
NO971863D0 (no)	1997-04-23
US5689002A (en)	1997-11-18
HUP9801837A3 (en)	2001-06-28
AU6788896A (en)	1997-03-27
CA2204734C (en)	2009-12-29
JPH10508878A (ja)	1998-09-02
MX9703341A (es)	1997-07-31
PL184937B1 (pl)	2003-01-31
HK1001861A1 (en)	1998-07-17
CA2204734A1 (en)	1997-03-13
NO971863L (no)	1997-04-23
EP0790979A1 (de)	1997-08-27
PL320027A1 (en)	1997-09-01
HUP9801837A2 (hu)	1998-12-28
DE69605528T2 (de)	2000-05-04
CN1070843C (zh)	2001-09-12
CN1164853A (zh)	1997-11-12
EP0790979B1 (de)	1999-12-08
HU220965B1 (hu)	2002-07-29
CZ288645B6 (cs)	2001-08-15
DE69605528D1 (de)	2000-01-13
NO308841B1 (no)	2000-11-06
KR100270411B1 (ko)	2000-11-01
ES2140887T3 (es)	2000-03-01
WO1997009300A1 (en)	1997-03-13

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Legal Events

Date	Code	Title	Description
2000-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties