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ATE170757T1 - Methode und reagentien um technetium-99m-komplexe herzustellen - Google Patents

Methode und reagentien um technetium-99m-komplexe herzustellen

Info

Publication number
ATE170757T1
ATE170757T1 AT91909080T AT91909080T ATE170757T1 AT E170757 T1 ATE170757 T1 AT E170757T1 AT 91909080 T AT91909080 T AT 91909080T AT 91909080 T AT91909080 T AT 91909080T AT E170757 T1 ATE170757 T1 AT E170757T1
Authority
AT
Austria
Prior art keywords
group
carboxy
alkyl group
hydrogen atom
pct
Prior art date
Application number
AT91909080T
Other languages
English (en)
Inventor
Alfons Verbruggen
Original Assignee
Mallinckrodt Medical Inc
Alfons Verbruggen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc, Alfons Verbruggen filed Critical Mallinckrodt Medical Inc
Application granted granted Critical
Publication of ATE170757T1 publication Critical patent/ATE170757T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91909080T 1990-04-17 1991-04-10 Methode und reagentien um technetium-99m-komplexe herzustellen ATE170757T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90200928 1990-04-17

Publications (1)

Publication Number Publication Date
ATE170757T1 true ATE170757T1 (de) 1998-09-15

Family

ID=8204992

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91909080T ATE170757T1 (de) 1990-04-17 1991-04-10 Methode und reagentien um technetium-99m-komplexe herzustellen

Country Status (8)

Country Link
US (1) US5268163A (de)
EP (1) EP0639082B1 (de)
JP (1) JP3005943B2 (de)
AT (1) ATE170757T1 (de)
AU (1) AU653153B2 (de)
CA (1) CA2080685A1 (de)
DE (1) DE69130182T2 (de)
WO (1) WO1991016076A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965392A (en) * 1987-03-26 1990-10-23 Neorx Corporation Chelating compounds for metal-radionuclide labeled proteins
US5208007A (en) * 1988-11-22 1993-05-04 Board Of Regents Of The University Of Oklahoma Isotopic tracer composition and method for making and using same
JP2860157B2 (ja) * 1990-10-31 1999-02-24 日本メジフィジックス株式会社 腎機能測定用の既放射能標識テクネチウムキレート注射剤の製造方法
EP0618191A1 (de) * 1993-04-02 1994-10-05 AMERSHAM INTERNATIONAL plc Metall-chelatierende Verbindungen
ATE162524T1 (de) * 1993-07-19 1998-02-15 Resolution Pharm Inc Hydrazine mit einer n3s konfiguration als radionukleide chelatoren
US5574140A (en) * 1993-09-03 1996-11-12 Resolution Pharmaceutical Inc. Hydrazino-type N2 S2 chelators
US5858327A (en) * 1993-09-03 1999-01-12 Resolutions Pharmaceuticals, Inc. Hydrazino-type N2 S2 radionuclide chelating compounds
US5986074A (en) * 1996-05-06 1999-11-16 Emory University Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof
US5886142A (en) * 1997-05-20 1999-03-23 Thomas Jefferson University Radiolabeled thrombus imaging agents
NL1006164C2 (nl) * 1997-05-29 1998-12-01 Univ Leiden Antimicrobiële peptiden.
US7067111B1 (en) 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
CN1292798C (zh) 2000-06-02 2007-01-03 德克萨斯州立大学董事会 乙二半胱氨酸(ec)－药物缀合物
CN1723042B (zh) 2002-11-07 2010-12-01 得克萨斯大学体系董事会 乙二半胱氨酸(ec)-药物结合物、组合物及用于组织特异性疾病显像的方法
US9050378B2 (en) 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
CA2593256A1 (en) * 2005-01-05 2006-07-13 Board Of Regents, The University Of Texas System Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications
US8758723B2 (en) * 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
GB201402132D0 (en) * 2014-02-07 2014-03-26 South African Nuclear Energy A method of producing ethylenedicysteine deoxyglucosamine (ECDG) or a salt thereof and its application in a kit

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571430A (en) * 1982-11-08 1986-02-18 Medi-Physics, Inc. Homocysteine and homocysteinamide derivatives
US4638051A (en) * 1984-04-30 1987-01-20 The Johns Hopkins University Brain imaging radiopharmaceuticals
IT1176481B (it) * 1984-07-25 1987-08-18 Vittorio Pastro Nuovo tipo di aste di poligonazione per linee aeree di contatto per trazione elettrica
GB8426845D0 (en) * 1984-10-24 1984-11-28 Amersham Int Plc Complexes of technetium-99m
CA1243329A (en) * 1985-03-11 1988-10-18 Amersham Int Plc TECHNETIUM COMPLEXES WITH PROPYLENE-AMINE-OXIMES
ES2017088B3 (es) * 1986-05-28 1991-01-01 Mallinckrodt Inc (A Missouri Corporation) Quelatos de tecnecio a utilizar para determinar la funcion renal.
US4988496A (en) * 1988-05-31 1991-01-29 Neorx Corporation Metal radionuclide chelating compounds for improved chelation kinetics
US4925650A (en) * 1988-11-16 1990-05-15 Mallinckrodt, Inc. Technetium -99m complex for examining the renal function

Also Published As

Publication number Publication date
EP0639082B1 (de) 1998-09-09
CA2080685A1 (en) 1991-10-18
AU653153B2 (en) 1994-09-22
DE69130182D1 (de) 1998-10-15
WO1991016076A1 (en) 1991-10-31
AU7799891A (en) 1991-11-11
EP0639082A4 (de) 1994-02-02
EP0639082A1 (de) 1995-02-22
JP3005943B2 (ja) 2000-02-07
US5268163A (en) 1993-12-07
DE69130182T2 (de) 1999-01-28
JPH05505617A (ja) 1993-08-19

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