ATE159945T1 - Beta-aminoalkyl und beta-n- peptidylaminoalkylborsäure - Google Patents
Beta-aminoalkyl und beta-n- peptidylaminoalkylborsäureInfo
- Publication number
- ATE159945T1 ATE159945T1 AT93918597T AT93918597T ATE159945T1 AT E159945 T1 ATE159945 T1 AT E159945T1 AT 93918597 T AT93918597 T AT 93918597T AT 93918597 T AT93918597 T AT 93918597T AT E159945 T1 ATE159945 T1 AT E159945T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- acid
- peptidylaminoalkylboric
- aminoalkyl
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38663—Stabilised liquid enzyme compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Detergent Compositions (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/931,809 US5442100A (en) | 1992-08-14 | 1992-08-14 | β-aminoalkyl and β-N-peptidylaminoalkyl boronic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE159945T1 true ATE159945T1 (de) | 1997-11-15 |
Family
ID=25461390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93918597T ATE159945T1 (de) | 1992-08-14 | 1993-08-03 | Beta-aminoalkyl und beta-n- peptidylaminoalkylborsäure |
Country Status (10)
Country | Link |
---|---|
US (2) | US5442100A (de) |
EP (1) | EP0655067B1 (de) |
JP (1) | JPH08500113A (de) |
CN (1) | CN1047596C (de) |
AT (1) | ATE159945T1 (de) |
AU (1) | AU4799793A (de) |
DE (1) | DE69315079T2 (de) |
MX (1) | MX9304970A (de) |
TW (1) | TW251274B (de) |
WO (1) | WO1994004542A1 (de) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2098484T3 (es) * | 1992-08-14 | 1997-05-01 | Procter & Gamble | Detergentes liquidos que contienen un acido alfa-amino-boronico. |
CN1127014A (zh) * | 1993-07-09 | 1996-07-17 | 诺沃挪第克公司 | 作为酶稳定剂的一烃基硼酸或二烃基硼酸衍生物 |
US5834415A (en) * | 1994-04-26 | 1998-11-10 | Novo Nordisk A/S | Naphthalene boronic acids |
DE4422433A1 (de) * | 1994-06-28 | 1996-01-04 | Cognis Bio Umwelt | Mehrenzymgranulat |
US5731439A (en) * | 1995-03-24 | 1998-03-24 | The Dupont Merck Pharmaceutical Company | Piperidine containing aminobornic acids |
US6036727A (en) | 1995-06-05 | 2000-03-14 | Creative Products Resource, Inc. | Anhydrous dry-cleaning compositions containing polysulfonic acid, and dry-cleaning kits for delicate fabrics |
US6086634A (en) | 1995-06-05 | 2000-07-11 | Custom Cleaner, Inc. | Dry-cleaning compositions containing polysulfonic acid |
AU5950696A (en) | 1995-06-05 | 1996-12-24 | Creative Products Resource, Inc. | Dry-cleaning kit for in-dryer use |
US5658651A (en) | 1995-09-29 | 1997-08-19 | Creative Products Resource, Inc. | Fabric treatment and softener system for in-dryer use |
DE69621131T2 (de) * | 1995-06-13 | 2002-11-28 | Novozymes A/S, Bagsvaerd | 4-substituierte-phenylboronsäuren als enzymstabilisatoren |
ATE509912T1 (de) * | 1999-06-14 | 2011-06-15 | Wisconsin Alumni Res Found | Oligomere und polymere von zyklischen imino- carbonsäuren |
EP1786891A1 (de) * | 2004-09-08 | 2007-05-23 | The Procter and Gamble Company | Wäschebehandlungszusammensetzungen mit verbessertem duft |
ES2568768T3 (es) * | 2008-01-04 | 2016-05-04 | The Procter & Gamble Company | Una composición detergente para lavado de ropa que comprende glicosil hidrolasa |
US20090209447A1 (en) | 2008-02-15 | 2009-08-20 | Michelle Meek | Cleaning compositions |
EP2300588B1 (de) | 2008-06-06 | 2019-02-06 | The Procter and Gamble Company | Waschmittel mit variante einer xyloglucocanase der familie 44 |
PL2318419T3 (pl) * | 2008-06-17 | 2015-08-31 | Millennium Pharm Inc | Związki estrów boronianowych i ich kompozycje farmaceutyczne |
WO2011005730A1 (en) | 2009-07-09 | 2011-01-13 | The Procter & Gamble Company | A catalytic laundry detergent composition comprising relatively low levels of water-soluble electrolyte |
JP2012532246A (ja) | 2009-07-09 | 2012-12-13 | ザ プロクター アンド ギャンブル カンパニー | 比較的低濃度の水溶性電解質を含む触媒性洗濯洗剤組成物 |
US8933131B2 (en) | 2010-01-12 | 2015-01-13 | The Procter & Gamble Company | Intermediates and surfactants useful in household cleaning and personal care compositions, and methods of making the same |
WO2011112910A1 (en) | 2010-03-12 | 2011-09-15 | The Procter & Gamble Company | Liquid detergent compositions comprising ph tuneable amido-gellants, and processes for making |
JP5571202B2 (ja) | 2010-03-12 | 2014-08-13 | ザ プロクター アンド ギャンブル カンパニー | ジアミドゲル化剤を含む流体洗剤組成物及び製造方法 |
HUE048859T2 (hu) | 2010-08-10 | 2020-08-28 | Rempex Pharmaceuticals Inc | Gyûrûs bórsavészter származékok, eljárás elõállításukra, és terápiás alkalmazásuk |
JP2014506581A (ja) | 2011-02-17 | 2014-03-17 | ザ プロクター アンド ギャンブル カンパニー | バイオベースの直鎖アルキルフェニルスルホネート |
EP2678410B1 (de) | 2011-02-17 | 2017-09-13 | The Procter and Gamble Company | Zusammensetzungen mit mischungen aus c10-c13-alkylphenyl-sulfonaten |
WO2013016371A1 (en) | 2011-07-25 | 2013-01-31 | The Procter & Gamble Company | Detergents having acceptable color |
US20130303427A1 (en) | 2011-09-13 | 2013-11-14 | Susana Fernandez Prieto | MICROCAPSULE COMPOSITIONS COMPRISING pH TUNEABLE DI-AMIDO GELLANTS |
RU2014131370A (ru) * | 2012-01-09 | 2016-02-27 | Юниверсити Оф Тромсё | Терапевтические соединения, содержащие бор |
EP2716644B1 (de) | 2012-10-03 | 2017-04-05 | The Procter and Gamble Company | Stabile Enzymstabilisatorvormischung |
KR20150103269A (ko) | 2013-01-04 | 2015-09-09 | 렘펙스 파머수티클스 인코퍼레이티드 | 보론산 유도체 및 그의 치료적 용도 |
US9241947B2 (en) | 2013-01-04 | 2016-01-26 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
EP2970830B1 (de) | 2013-03-14 | 2017-12-13 | Novozymes A/S | Protease und hemmer enthaltend in wasserlöslichen filmen |
MX365786B (es) | 2013-05-03 | 2019-06-14 | Novozymes As | Microencapsulacion de enzimas detergentes. |
SMT201900611T1 (it) | 2014-05-05 | 2020-01-14 | Rempex Pharmaceuticals Inc | Sintesi di sali boronati e usi degli stessi |
ES2985626T3 (es) | 2014-05-05 | 2024-11-06 | Melinta Therapeutics Inc | Sales y polimorfos de derivados cíclicos de éster de ácido borónico y usos terapéuticos de los mismos |
KR20170007448A (ko) | 2014-05-19 | 2017-01-18 | 렘펙스 파머수티클스 인코퍼레이티드 | 보론산 유도체 및 그의 치료적 용도 |
CN106659761A (zh) | 2014-05-20 | 2017-05-10 | 千年药物公司 | 初级癌症疗法后使用的含硼蛋白酶体抑制剂 |
KR20170024087A (ko) | 2014-07-01 | 2017-03-06 | 렘펙스 파머수티클스 인코퍼레이티드 | 보론산 유도체 및 그의 치료적 용도 |
WO2016001319A1 (en) | 2014-07-03 | 2016-01-07 | Novozymes A/S | Improved stabilization of non-protease enzyme |
US10662205B2 (en) | 2014-11-18 | 2020-05-26 | Qpex Biopharma, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
CN117904083A (zh) | 2014-12-19 | 2024-04-19 | 诺维信公司 | 蛋白酶变体以及对其进行编码的多核苷酸 |
US10364257B2 (en) | 2014-12-19 | 2019-07-30 | Rempex Pharmaceuticals, Inc. | Apparatus and continuous flow process for production of boronic acid derivatives |
US20180051041A1 (en) | 2015-03-17 | 2018-02-22 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
CN107969136B (zh) | 2015-07-06 | 2021-12-21 | 诺维信公司 | 脂肪酶变体以及编码它们的多核苷酸 |
US10675589B2 (en) | 2015-10-14 | 2020-06-09 | Novozymes A/S | Cleaning of water filtration membranes |
MX389349B (es) | 2016-06-30 | 2025-03-20 | Qpex Biopharma Inc | Derivados de ácido borónico y usos terapéuticos de los mismos. |
WO2018202846A1 (en) | 2017-05-05 | 2018-11-08 | Novozymes A/S | Compositions comprising lipase and sulfite |
WO2019002356A1 (en) | 2017-06-30 | 2019-01-03 | Novozymes A/S | ENZYMATIC SUSPENSION COMPOSITION |
KR102626967B1 (ko) | 2017-10-11 | 2024-01-18 | 큐펙스 바이오파마 인코포레이티드 | 보론산 유도체 및 이의 합성 |
BR112020008737A2 (pt) | 2017-11-01 | 2020-10-13 | Novozymes A/S | polipeptídeos e composições que compreendam tais polipeptídeos |
EP3704240A1 (de) | 2017-11-01 | 2020-09-09 | Novozymes A/S | Polypeptide und zusammensetzungen mit solchen polypeptiden |
WO2019175240A1 (en) | 2018-03-13 | 2019-09-19 | Novozymes A/S | Microencapsulation using amino sugar oligomers |
CA3097127A1 (en) | 2018-04-20 | 2019-10-24 | Qpex Biopharma, Inc. | Boronic acid derivatives and therapeutic uses thereof |
EP3647397A1 (de) | 2018-10-31 | 2020-05-06 | Henkel AG & Co. KGaA | Reinigungsmittel mit dispersins iv |
ES2981999T3 (es) | 2018-10-31 | 2024-10-14 | Henkel Ag & Co Kgaa | Composiciones limpiadoras que contienen dispersinas V |
US11879110B2 (en) | 2019-11-27 | 2024-01-23 | The Procter & Gamble Company | Alkylbenzenesulfonate surfactants |
US20220411773A1 (en) | 2019-12-20 | 2022-12-29 | Novozymes A/S | Polypeptides having proteolytic activity and use thereof |
WO2022189521A1 (en) | 2021-03-12 | 2022-09-15 | Novozymes A/S | Polypeptide variants |
WO2024131880A2 (en) | 2022-12-23 | 2024-06-27 | Novozymes A/S | Detergent composition comprising catalase and amylase |
Family Cites Families (31)
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---|---|---|---|---|
US2872479A (en) * | 1955-06-30 | 1959-02-03 | Callery Chemical Co | Preparation of organoboron compounds |
US3912595A (en) * | 1974-02-25 | 1975-10-14 | Us Health | Method of purifying enzymes using boronic acids covalently bonded to an insoluble support |
IT1129814B (it) * | 1980-07-02 | 1986-06-11 | Unilever Nv | Composizione detergente enzimatica liquida |
US4462922A (en) * | 1981-11-19 | 1984-07-31 | Lever Brothers Company | Enzymatic liquid detergent composition |
GB8311314D0 (en) * | 1983-04-26 | 1983-06-02 | Unilever Plc | Aqueous enzyme-containing compositions |
US4652394A (en) * | 1983-05-31 | 1987-03-24 | Colgate Palmolive Co. | Built single phase liquid anionic detergent compositions containing stabilized enzymes |
DE3413571A1 (de) * | 1984-04-11 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verwendung von kristallinen schichtfoermigen natriumsilikaten zur wasserenthaertung und verfahren zur wasserenthaertung |
US4537707A (en) * | 1984-05-14 | 1985-08-27 | The Procter & Gamble Company | Liquid detergents containing boric acid and formate to stabilize enzymes |
US4566985A (en) * | 1984-09-19 | 1986-01-28 | Applied Biochemists, Inc. | Method of cleaning using liquid compositions comprising stabilized mixtures of enzymes |
US4747977A (en) * | 1984-11-09 | 1988-05-31 | The Procter & Gamble Company | Ethanol-free liquid laundry detergent compositions |
US4842769A (en) * | 1985-07-26 | 1989-06-27 | Colgate-Palmolive Co. | Stabilized fabric softening built detergent composition containing enzymes |
US4900475A (en) * | 1985-07-26 | 1990-02-13 | Colgate-Palmolive Co. | Stabilized built liquid detergent composition containing enzyme |
JPH0697997B2 (ja) * | 1985-08-09 | 1994-12-07 | ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ | 新規の酵素的洗浄剤添加物 |
EG18543A (en) * | 1986-02-20 | 1993-07-30 | Albright & Wilson | Protected enzyme systems |
US4842758A (en) * | 1986-10-31 | 1989-06-27 | Colgate-Palmolive Company | Stabilized enzyme system for use in aqueous liquid built detergent compositions |
US4704233A (en) * | 1986-11-10 | 1987-11-03 | The Procter & Gamble Company | Detergent compositions containing ethylenediamine-N,N'-disuccinic acid |
US5187157A (en) * | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
DK571587D0 (da) * | 1987-11-02 | 1987-11-02 | Novo Industri As | Enzymatisk detergentsammensaetning |
EP0315574A3 (de) * | 1987-11-05 | 1990-08-22 | Hoechst Aktiengesellschaft | Renin-Inhibitoren |
GB8810822D0 (en) * | 1988-05-06 | 1988-06-08 | Unilever Plc | Liquid detergent compositions |
US4963655A (en) * | 1988-05-27 | 1990-10-16 | Mayo Foundation For Medical Education And Research | Boron analogs of amino acid/peptide protease inhibitors |
US5039446A (en) * | 1988-07-01 | 1991-08-13 | Genencor International, Inc. | Liquid detergent with stabilized enzyme |
DE3840452A1 (de) * | 1988-12-01 | 1990-06-07 | Hoechst Ag | (beta)-amino-boronsaeure-derivate |
CA2006527A1 (en) * | 1988-12-30 | 1990-06-30 | Martin S. Cardinali | Enzymatic liquid detergent compositions |
US4959179A (en) * | 1989-01-30 | 1990-09-25 | Lever Brothers Company | Stabilized enzymes liquid detergent composition containing lipase and protease |
US4908150A (en) * | 1989-02-02 | 1990-03-13 | Lever Brothers Company | Stabilized lipolytic enzyme-containing liquid detergent composition |
EP0385401A1 (de) * | 1989-02-27 | 1990-09-05 | Occidental Chemical Corporation | Besondere Mikrobielle Lipasen mit einer Aktivität bei Temperaturen und pH-Werten, die ihnen für die Verwendung in Detergentien Eignung verleiht |
DE69033423T2 (de) * | 1989-05-15 | 2000-05-25 | The Clorox Co., Oakland | Wäschewaschverfahren |
EP0450702A3 (en) * | 1990-04-06 | 1993-06-02 | Unilever N.V. | Process for preparing liquid enzymatic detergent compositions |
EP0478050A1 (de) * | 1990-09-24 | 1992-04-01 | Unilever N.V. | Detergentzusammensetzung |
EP0486073B1 (de) * | 1990-11-14 | 1996-07-24 | The Procter & Gamble Company | Lipase- und proteasehaltige flüssige Waschmittelzusammensetzung |
-
1992
- 1992-08-14 US US07/931,809 patent/US5442100A/en not_active Expired - Fee Related
-
1993
- 1993-08-03 AU AU47997/93A patent/AU4799793A/en not_active Abandoned
- 1993-08-03 DE DE69315079T patent/DE69315079T2/de not_active Expired - Fee Related
- 1993-08-03 EP EP93918597A patent/EP0655067B1/de not_active Expired - Lifetime
- 1993-08-03 AT AT93918597T patent/ATE159945T1/de not_active IP Right Cessation
- 1993-08-03 JP JP6506312A patent/JPH08500113A/ja active Pending
- 1993-08-03 WO PCT/US1993/007276 patent/WO1994004542A1/en active IP Right Grant
- 1993-08-14 CN CN93117839A patent/CN1047596C/zh not_active Expired - Fee Related
- 1993-08-16 MX MX9304970A patent/MX9304970A/es not_active IP Right Cessation
- 1993-10-13 TW TW082108452A patent/TW251274B/zh active
-
1995
- 1995-05-04 US US08/434,901 patent/US5488157A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1994004542A1 (en) | 1994-03-03 |
US5488157A (en) | 1996-01-30 |
EP0655067B1 (de) | 1997-11-05 |
US5442100A (en) | 1995-08-15 |
EP0655067A1 (de) | 1995-05-31 |
CN1047596C (zh) | 1999-12-22 |
DE69315079T2 (de) | 1998-06-04 |
AU4799793A (en) | 1994-03-15 |
DE69315079D1 (de) | 1997-12-11 |
TW251274B (de) | 1995-07-11 |
CN1090850A (zh) | 1994-08-17 |
JPH08500113A (ja) | 1996-01-09 |
MX9304970A (es) | 1994-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |