ATE149510T1 - 2'-deoxy-2'-fluorcoformycin und stereoisomere davon - Google Patents
2'-deoxy-2'-fluorcoformycin und stereoisomere davonInfo
- Publication number
- ATE149510T1 ATE149510T1 AT92923538T AT92923538T ATE149510T1 AT E149510 T1 ATE149510 T1 AT E149510T1 AT 92923538 T AT92923538 T AT 92923538T AT 92923538 T AT92923538 T AT 92923538T AT E149510 T1 ATE149510 T1 AT E149510T1
- Authority
- AT
- Austria
- Prior art keywords
- deoxy
- fluorocoformycin
- epi
- benzoyl
- fluoro
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000003541 multi-stage reaction Methods 0.000 abstract 2
- 101710169336 5'-deoxyadenosine deaminase Proteins 0.000 abstract 1
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 abstract 1
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 abstract 1
- 102000055025 Adenosine deaminases Human genes 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 abstract 1
- YYVZPZJEMLBIGM-TWMKSMIVSA-N [(2r,3r,4s,5r)-3-benzoyloxy-5-bromo-4-fluorooxolan-2-yl]methyl benzoate Chemical compound C([C@H]1O[C@H](Br)[C@H]([C@@H]1OC(=O)C=1C=CC=CC=1)F)OC(=O)C1=CC=CC=C1 YYVZPZJEMLBIGM-TWMKSMIVSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F01—MACHINES OR ENGINES IN GENERAL; ENGINE PLANTS IN GENERAL; STEAM ENGINES
- F01K—STEAM ENGINE PLANTS; STEAM ACCUMULATORS; ENGINE PLANTS NOT OTHERWISE PROVIDED FOR; ENGINES USING SPECIAL WORKING FLUIDS OR CYCLES
- F01K23/00—Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids
- F01K23/02—Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled
- F01K23/06—Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle
- F01K23/10—Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Combustion & Propulsion (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP35258891 | 1991-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE149510T1 true ATE149510T1 (de) | 1997-03-15 |
Family
ID=18425076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92923538T ATE149510T1 (de) | 1991-11-14 | 1992-11-13 | 2'-deoxy-2'-fluorcoformycin und stereoisomere davon |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0643069B1 (de) |
| JP (1) | JP3030087B2 (de) |
| KR (1) | KR0163799B1 (de) |
| AT (1) | ATE149510T1 (de) |
| AU (1) | AU661520B2 (de) |
| CA (1) | CA2122815C (de) |
| DE (1) | DE69218005T2 (de) |
| DK (1) | DK0643069T3 (de) |
| ES (1) | ES2099841T3 (de) |
| NO (1) | NO301231B1 (de) |
| WO (1) | WO1993010137A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09241294A (ja) * | 1996-03-07 | 1997-09-16 | Microbial Chem Res Found | ２′−デオキシ−２′−ハロコホルマイシン又はその立体異性体の製造法 |
| JP6045641B1 (ja) * | 2015-06-04 | 2016-12-14 | 株式会社 資生堂 | 化粧容器 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4625020A (en) * | 1983-11-18 | 1986-11-25 | Bristol-Myers Company | Nucleoside process |
| DE3562623D1 (en) * | 1984-03-16 | 1988-06-16 | Warner Lambert Co | 2'-chloropentostatin, a pharmaceutical composition comprising the compound and a novel microorganism for producing the compound |
| JPS61199797A (ja) * | 1985-02-28 | 1986-09-04 | Kitasato Inst:The | 新規化合物アデクロリンおよびその製造法 |
| JPH0631298B2 (ja) * | 1985-12-18 | 1994-04-27 | 財団法人微生物化学研究会 | 新規アンスラサイクリン誘導体，抗腫瘍剤，及び製造法 |
| JPH0798832B2 (ja) * | 1987-05-01 | 1995-10-25 | 財団法人微生物化学研究会 | イミダゾジアゼピン誘導体 |
-
1992
- 1992-11-13 ES ES92923538T patent/ES2099841T3/es not_active Expired - Lifetime
- 1992-11-13 DE DE69218005T patent/DE69218005T2/de not_active Expired - Fee Related
- 1992-11-13 JP JP5509148A patent/JP3030087B2/ja not_active Expired - Lifetime
- 1992-11-13 EP EP92923538A patent/EP0643069B1/de not_active Expired - Lifetime
- 1992-11-13 WO PCT/JP1992/001489 patent/WO1993010137A1/ja active IP Right Grant
- 1992-11-13 AT AT92923538T patent/ATE149510T1/de not_active IP Right Cessation
- 1992-11-13 DK DK92923538.0T patent/DK0643069T3/da active
- 1992-11-13 KR KR1019940701645A patent/KR0163799B1/ko not_active IP Right Cessation
- 1992-11-13 CA CA002122815A patent/CA2122815C/en not_active Expired - Fee Related
- 1992-11-13 AU AU29318/92A patent/AU661520B2/en not_active Ceased
-
1994
- 1994-05-13 NO NO941800A patent/NO301231B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0643069B1 (de) | 1997-03-05 |
| NO301231B1 (no) | 1997-09-29 |
| AU661520B2 (en) | 1995-07-27 |
| CA2122815C (en) | 1998-09-15 |
| EP0643069A1 (de) | 1995-03-15 |
| DE69218005D1 (de) | 1997-04-10 |
| KR0163799B1 (ko) | 1998-11-16 |
| ES2099841T3 (es) | 1997-06-01 |
| JPH06511062A (ja) | 1994-12-08 |
| JP3030087B2 (ja) | 2000-04-10 |
| WO1993010137A1 (en) | 1993-05-27 |
| EP0643069A4 (de) | 1994-11-22 |
| CA2122815A1 (en) | 1993-05-27 |
| NO941800D0 (no) | 1994-05-13 |
| DE69218005T2 (de) | 1997-10-16 |
| AU2931892A (en) | 1993-06-15 |
| NO941800L (no) | 1994-07-04 |
| DK0643069T3 (da) | 1997-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |