[go: up one dir, main page]

ATE148168T1 - Monoklonale antikörper - Google Patents

Monoklonale antikörper

Info

Publication number
ATE148168T1
ATE148168T1 AT90916718T AT90916718T ATE148168T1 AT E148168 T1 ATE148168 T1 AT E148168T1 AT 90916718 T AT90916718 T AT 90916718T AT 90916718 T AT90916718 T AT 90916718T AT E148168 T1 ATE148168 T1 AT E148168T1
Authority
AT
Austria
Prior art keywords
rhesus
antibody molecules
monoclonal antibodies
chimeric antibody
antibodies
Prior art date
Application number
AT90916718T
Other languages
English (en)
Inventor
Nevin Campbell Hughes-Jones
Original Assignee
Nat Blood Authority
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Blood Authority filed Critical Nat Blood Authority
Application granted granted Critical
Publication of ATE148168T1 publication Critical patent/ATE148168T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/461Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464Igs containing CDR-residues from one specie grafted between FR-residues from another
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90916718T 1989-11-13 1990-11-13 Monoklonale antikörper ATE148168T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898925590A GB8925590D0 (en) 1989-11-13 1989-11-13 Monoclonal antibodies

Publications (1)

Publication Number Publication Date
ATE148168T1 true ATE148168T1 (de) 1997-02-15

Family

ID=10666204

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90916718T ATE148168T1 (de) 1989-11-13 1990-11-13 Monoklonale antikörper

Country Status (11)

Country Link
US (2) US5831063A (de)
EP (1) EP0500659B1 (de)
AT (1) ATE148168T1 (de)
AU (1) AU647054B2 (de)
CA (1) CA2068222C (de)
DE (1) DE69029808T2 (de)
DK (1) DK0500659T3 (de)
ES (1) ES2098274T3 (de)
GB (1) GB8925590D0 (de)
GR (1) GR3022847T3 (de)
WO (1) WO1991007492A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5495002A (en) * 1984-01-31 1996-02-27 Akzo N.V. Tumor associated monoclonal antibody 123AV16
GB9020282D0 (en) 1990-09-17 1990-10-31 Gorman Scott D Altered antibodies and their preparation
US6326488B1 (en) 1990-10-19 2001-12-04 Board Of Trustees Of University Of Illinois Gene and genetic elements associated with sensitivity to chemotherapeutic drugs
WO1992022653A1 (en) 1991-06-14 1992-12-23 Genentech, Inc. Method for making humanized antibodies
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
KR100255717B1 (ko) * 1991-07-15 2000-05-01 그레이엄 브레레톤 항체의 생산방법
FR2724182B1 (fr) * 1994-09-02 1996-12-13 Pasteur Institut Obtention d'un anticorps monoclonal recombinant a partir d'un anticorps monoclonal humain anti-rhesus d, sa production en cellules d'insecte, et ses utilisations
SK284879B6 (sk) 1996-06-24 2006-01-05 Zlb Behring Ag Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie
JP5198704B2 (ja) 2000-03-03 2013-05-15 メディミューン リミティド エオタキシンに対するヒト抗体及びそれらの使用
US6946546B2 (en) 2000-03-06 2005-09-20 Cambridge Antibody Technology Limited Human antibodies against eotaxin
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
WO2002074969A2 (en) * 2001-01-26 2002-09-26 University Of Lausanne Matrix attachment regions and methods for use thereof
WO2003000908A1 (en) * 2001-06-21 2003-01-03 Ecole Polytechnique Federale De Lausanne A method for introducing a nucleic acid into a eukaryotic cell
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7658924B2 (en) * 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
GB0324368D0 (en) * 2003-10-17 2003-11-19 Univ Cambridge Tech Polypeptides including modified constant regions
US8252917B2 (en) 2003-10-24 2012-08-28 Selexis S.A. High efficiency gene transfer and expression in mammalian cells by a multiple transfection procedure of MAR sequences
US8679502B2 (en) * 2007-11-13 2014-03-25 Evec Inc. Monoclonal antibodies that bind to HGM-CSF and medical compositions comprising same
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
WO2025039046A1 (en) * 2023-08-23 2025-02-27 The Walter And Eliza Hall Institute Of Medical Research Anti-rhesus d human monoclonal antibodies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
GB8610106D0 (en) * 1986-04-25 1986-05-29 Central Blood Lab Authority Human igm-producing heterohybridoma
AU622417B2 (en) * 1987-09-18 1992-04-09 National Blood Authority Human anti-rh(d) monoclonal antibodies
AU623345B2 (en) * 1987-09-18 1992-05-14 National Blood Authority Human anti-rh(d) monoclonal antibodies

Also Published As

Publication number Publication date
GR3022847T3 (en) 1997-06-30
CA2068222C (en) 1999-05-11
US5831063A (en) 1998-11-03
AU6721490A (en) 1991-06-13
AU647054B2 (en) 1994-03-17
WO1991007492A1 (en) 1991-05-30
EP0500659A1 (de) 1992-09-02
EP0500659B1 (de) 1997-01-22
CA2068222A1 (en) 1991-05-14
US5919910A (en) 1999-07-06
GB8925590D0 (en) 1990-01-04
DK0500659T3 (da) 1997-07-14
DE69029808T2 (de) 1997-07-10
ES2098274T3 (es) 1997-05-01
DE69029808D1 (de) 1997-03-06

Similar Documents

Publication Publication Date Title
DK0500659T3 (da) Monoklonale antistoffer.
BR9507594B1 (pt) anticorpo monoclonal com scfv humanizado, molécula de ácido nucleico recombinante e proteìna recombinante.
WO2002020569A3 (en) Mammalian genes; related reagents and methods
CY1108545T1 (el) Πρωτεϊνες υπομοναδας υποδοχεα κυτοκινης θηλαστικου, σχετικα αντιδραστηρια και μεθοδοι
ATE373719T1 (de) Humanisierte antikörper gegen ccr2 und verfahren zur deren verwendung
WO1998050433A3 (en) Human monoclonal antibodies to epidermal growth factor receptor
WO2003060080A3 (en) Canine immunoglobulin variable domains, caninized antibodies, and methods for making and using them
ATE137534T1 (de) Cdr-gepfropfte anti-cea-antikörper und ihre herstellung
DK0784683T3 (da) TIE-2-ligander, fremgangsmåder til dannelse af disse og anvendelser deraf
DE69531679D1 (de) Für e-selectin und p-selectin spezifische kreuzreaktive monoklonale antikörper
EP1394253A4 (de) Gegen menschliches ovarialkarzinom und gegen cd3 gerichteter bispezifischer antikörper
DK0460076T3 (da) Genetisk manipulerede immunoglobuliner
WO2001090358A3 (en) Mammalian receptor proteins; related reagents and methods
ATE370235T1 (de) Rekombinantpeptide hergeleitet vom mc3 antikörper gegen ba46, verfahren zu deren verwendung und verfahren zur humanisierung von antikörperpeptiden
EP1433792A3 (de) Menschlische-rezeptor Proteine; verwandte Reagenzien und Methoden
NO986088L (no) Polypeptider med evnen til Õ danne antigenbindende strukturer med spesifisitet for Rhesus D-antigener, DNA som koder for disse, fremgangsmÕter for fremstilling av disse og anvendelse av disse
DE69531311D1 (de) Monoklonale antikörper spezifisch für endprodukte der fortgeschrittenen glycosylation in biologischen proben
DE60238987D1 (de) Behandlung von bauchspeicheldrüsenkrebs mit einem monoklonalen antikörper
PT939809E (pt) Ligandos do receptor de tie-2 (ligando 3 de tie e ligando 4 de tie) e suas utilizacoes
WO1999046379A3 (en) Human receptor proteins; related reagents and methods
DK1181366T3 (da) Mammale receptorproteiner, beslægtede reagenser og fremgangsmåder
FR2560212B1 (fr) Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps
WO2001057219A3 (en) Mammalian interleukin-1-delta and -epsilon. their use in therapeutic and diagnostic methods
WO2002000005A8 (en) Libraries displaying human antibody fragments with hybrid complementarity determining regions
MXPA04004658A (es) Anticuerpos monoclonales especificos para tumores.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee