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ATE123306T1 - Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen. - Google Patents

Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.

Info

Publication number
ATE123306T1
ATE123306T1 AT90303484T AT90303484T ATE123306T1 AT E123306 T1 ATE123306 T1 AT E123306T1 AT 90303484 T AT90303484 T AT 90303484T AT 90303484 T AT90303484 T AT 90303484T AT E123306 T1 ATE123306 T1 AT E123306T1
Authority
AT
Austria
Prior art keywords
ascorbic acid
alpha
glycosyl
preparation
saccharide
Prior art date
Application number
AT90303484T
Other languages
English (en)
Inventor
Itaru Yamamoto
Norio Muto
Toshio Miyake
Original Assignee
Hayashibara Biochem Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1274518A external-priority patent/JP2926412B2/ja
Application filed by Hayashibara Biochem Lab filed Critical Hayashibara Biochem Lab
Application granted granted Critical
Publication of ATE123306T1 publication Critical patent/ATE123306T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/82Acid flavourants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/16Preparation of compounds containing saccharide radicals produced by the action of an alpha-1, 6-glucosidase, e.g. amylose, debranched amylopectin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/58Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound through only acyclic carbon atoms to a non-saccharide heterocyclic ring, e.g. bleomycin, phleomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/522Antioxidants; Radical scavengers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Saccharide Compounds (AREA)
AT90303484T 1989-05-19 1990-03-30 Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen. ATE123306T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12707289 1989-05-19
JP1274518A JP2926412B2 (ja) 1989-05-19 1989-10-20 α―グリコシル―L―アスコルビン酸とその製造方法並びに用途

Publications (1)

Publication Number Publication Date
ATE123306T1 true ATE123306T1 (de) 1995-06-15

Family

ID=26463107

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90303484T ATE123306T1 (de) 1989-05-19 1990-03-30 Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.

Country Status (7)

Country Link
US (3) US5137723A (de)
EP (1) EP0398484B1 (de)
AT (1) ATE123306T1 (de)
DE (1) DE69019779T2 (de)
DK (1) DK0398484T3 (de)
ES (1) ES2075148T3 (de)
HK (1) HK111196A (de)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE123306T1 (de) * 1989-05-19 1995-06-15 Hayashibara Biochem Lab Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.
JP2832848B2 (ja) * 1989-10-21 1998-12-09 株式会社林原生物化学研究所 結晶2―O―α―D―グルコピラノシル―L―アスコルビン酸とその製造方法並びに用途
JP2926432B2 (ja) * 1990-06-11 1999-07-28 株式会社林原生物化学研究所 養毛剤
TW197375B (de) * 1990-11-19 1993-01-01 Hayashibara Biochem Lab
US5215767A (en) * 1991-03-16 1993-06-01 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Additive for aquaculture feed for fish and shellfish and aquaculture feed for fish and shellfish which contains same
US5272136A (en) * 1991-10-12 1993-12-21 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo 5-0-α-D-Glucopyranosyl-L-ascorbic acid, and its preparation and uses
JP3072535B2 (ja) * 1991-10-21 2000-07-31 株式会社林原生物化学研究所 5−O−α−D−グルコピラノシル−L−アスコルビン酸とその製造方法並びに用途
JP3134235B2 (ja) * 1991-10-23 2001-02-13 株式会社林原生物化学研究所 2−O−α−D−グルコピラノシル−L−アスコルビン酸高含有物の製造方法
US5314678A (en) * 1992-01-28 1994-05-24 Mallinckrodt Medical, Inc. Sodium iodide 131 I capsules
JP3134236B2 (ja) * 1992-01-30 2001-02-13 株式会社林原生物化学研究所 α−グリコシル−L−アスコルビン酸高含有物の製造方法とその製造のための分離システム
EP0561585B1 (de) * 1992-03-17 1997-05-28 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Verfahren zur Herstellung von pulverförmigem kristallinem Maltitol
EP0649648B1 (de) * 1993-10-26 2001-09-19 Shiseido Company Limited Hautbleichende Mittel enthaltend Glykoside
US5455035A (en) * 1994-01-13 1995-10-03 Elizabeth Arden Company, Division Of Conopco, Inc. Clear two-phase cosmetic composition
US5935584A (en) * 1994-01-13 1999-08-10 Elizabeth Arden Company Vitamin C delivery system
GB9403855D0 (en) * 1994-03-01 1994-04-20 Scotia Holdings Plc Fatty acid derivatives
US5573398A (en) * 1994-06-10 1996-11-12 Towle; Lawrence E. Dental hygiene device and cleaning solution
US5837222A (en) * 1994-06-10 1998-11-17 Cloonan; Richard A. Liquid dental cleaning solution
US6224376B1 (en) 1994-06-10 2001-05-01 Richard A. Cloonan Dental cleaning liquid and gel
FR2733148B1 (fr) * 1995-04-20 1997-05-30 Oreal Composition pour lutter contre les taches et/ou le vieillissement de la peau, ses utilisations
US5853741A (en) * 1996-06-28 1998-12-29 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Vitamin C delivery system
JP4981198B2 (ja) 1998-03-31 2012-07-18 格 山本 グリコシル−l−アスコルビン酸のアシル化誘導体
US6656920B2 (en) 2000-04-04 2003-12-02 Amarillo Biosciences, Inc. Composition and method for promoting oral health
FR2807322B1 (fr) 2000-04-10 2004-02-20 Oreal Composition, notamment cosmetique, comprenant de l'acide ascorbique en association avec un derive d'acide ascorbique
FR2807320B1 (fr) * 2000-04-10 2002-05-24 Oreal Utilisation de derives d'acide ascorbique pour augmenter la synthese des creramides epidermiques
JP2002326924A (ja) * 2001-05-07 2002-11-15 Hayashibara Biochem Lab Inc 洗顔料
KR100440191B1 (ko) * 2001-08-23 2004-07-12 박관화 항산화 효과 및 높은 안정성을 갖는 아스코르브산 유도체및 그것의 제조방법
KR100440190B1 (ko) * 2001-08-23 2004-07-12 박관화 아카비오신-글루코실 아스코르베이트 및 그의 제조방법
FR2834641B1 (fr) * 2002-01-14 2005-04-22 Ct Regional De Lutte Contre Le Protection de la neurotoxicite de l'oxaliplatine par administration de calcium et de magnesium
KR20030080869A (ko) * 2002-04-11 2003-10-17 주식회사 코리아나화장품 아스코르브산 2-글루코시드를 포함하는 피부 미백용화장료 조성물
JP4043312B2 (ja) * 2002-08-06 2008-02-06 株式会社林原生物化学研究所 2−O−α−D−グルコピラノシル−L−アスコルビン酸の製造方法
KR20040038438A (ko) * 2002-11-01 2004-05-08 주식회사 코리아나화장품 아스코르브산 2-글루코시드 및 송이 추출물을 포함하는피부 미백용 화장료 조성물
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
KR100511419B1 (ko) * 2003-09-15 2005-08-30 한국생명공학연구원 베타-프럭토실-엘-아스코르브산 및 그의 제조방법
WO2006079212A1 (en) 2005-01-26 2006-08-03 Diamedica Inc. Use of s-adenosylmethionme, vitamin e, and vitamin c for the treatment of oxidative liver injury or insulin resistance
JP4766653B2 (ja) * 2005-01-28 2011-09-07 株式会社林原生物化学研究所 眼科用医薬組成物
WO2006090939A1 (en) * 2005-02-23 2006-08-31 Bioland Ltd. Cosmetic composition comprising beta-fructosyl-l-ascorbic acid for skin whitening
KR20080025036A (ko) * 2005-03-23 2008-03-19 마리 케이 인코포레이티드 피부 미백 조성물
WO2006137129A1 (ja) * 2005-06-21 2006-12-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo 皮膚外用剤
KR100691540B1 (ko) * 2006-06-22 2007-03-12 주식회사 펩트론 펩타이드가 결합된 안정화된 비타민 c 유도체, 이의제조방법 및 이를 함유하는 조성물
EP2129231A4 (de) * 2007-02-01 2015-01-21 Nat Res Council Canada Formulierungen lipophiler bioaktiver moleküle
AU2008256819A1 (en) * 2007-05-23 2008-12-04 Allergan, Inc. Cross-linked collagen and uses thereof
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US20100204464A1 (en) * 2007-09-14 2010-08-12 Nanjing Zhongshi Chemical Co., Ltd. Ascorbic acid derivatives, their preparation methods, intermediates and uses in cosmetics
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
MX2010005331A (es) 2007-11-16 2010-08-11 Vicept Therapeutics Inc Composiciones y metodos para tratamiento de purpura.
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394784B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP3184552B1 (de) 2008-09-02 2020-08-12 Tautona Group LP Stränge aus hyaluronsäure, verfahren zur herstellung davon und verwendungen davon
JP4885245B2 (ja) * 2009-01-15 2012-02-29 日本航空電子工業株式会社 Rdコンバータ及び角度検出装置
SG180307A1 (en) * 2009-09-03 2012-06-28 Hayashibara Biochem Lab Powder containing anhydrous crystals of 2-o-a-d-glucosyl-l-ascorbic acid, manufacturing method therefor, and use thereof
WO2012121297A1 (ja) 2011-03-07 2012-09-13 株式会社林原 2-O-α-D-グルコシル-L-アスコルビン酸無水結晶含有粉末の製造方法
WO2011030816A1 (ja) * 2009-09-14 2011-03-17 国立大学法人北海道大学 抗植物ウイルス剤
AU2010319539B2 (en) * 2009-11-10 2015-10-22 Mycell Technologies, Llc Stabilized formulations of fatty acids
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20110171310A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
AU2010348090B2 (en) 2010-03-12 2015-09-03 Allergan Industrie Sas A fluid composition comprising a hyaluronan polymer and mannitol for improving skin condition
CA2794254C (en) 2010-03-22 2018-09-04 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
EP2714002B1 (de) 2011-06-03 2019-04-03 Allergan, Inc. Dermale füllstoffzusammensetzungen mit antioxidantien
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
AU2012298791B2 (en) 2011-08-25 2015-09-24 Allergan Industrie, Sas Dermal filler compositions including antioxidants
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
WO2014103475A1 (ja) 2012-12-27 2014-07-03 株式会社林原 アンチエイジング用皮膚外用組成物及びその製造方法
CN103755756B (zh) * 2014-02-11 2015-07-08 江苏诚信药业有限公司 一种制备维生素c葡萄糖苷的工艺系统及其工艺方法
US10722444B2 (en) 2014-09-30 2020-07-28 Allergan Industrie, Sas Stable hydrogel compositions including additives
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
US20210402064A1 (en) 2018-05-09 2021-12-30 The Johns Hopkins University Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration
EP3790602A1 (de) 2018-05-09 2021-03-17 The Johns Hopkins University Nanofaserhydrogel-verbundstoffe für zell- und gewebefreisetzung
EP4129283A4 (de) 2020-03-31 2024-04-24 Natural Medicine Institute of Zhejiang Yangshengtang Co., Ltd. Pharmazeutische kombination und verwendung davon
WO2021197334A1 (zh) 2020-03-31 2021-10-07 浙江养生堂天然药物研究所有限公司 药物组合及其用途
WO2021213455A1 (zh) 2020-04-23 2021-10-28 浙江养生堂天然药物研究所有限公司 药物组合及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD33788A (de) *
JPS4838158B1 (de) * 1970-10-05 1973-11-15
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
DD141832A1 (de) * 1978-10-31 1980-05-21 Joachim Schmidt Verfahren und vorrichtung zur herstellung von l-ascorbinsaeure
EP0112332B1 (de) * 1982-06-30 1993-06-16 The General Hospital Corporation Vitamin d glycoside
JPS60130582A (ja) * 1983-12-19 1985-07-12 Takeda Chem Ind Ltd 食品用酸化防止剤,アスコルビン酸誘導体およびその製造法
US4822816A (en) * 1987-04-10 1989-04-18 Oxycal Laboratories, Inc. Compositions and methods for administering vitamin C
ATE123306T1 (de) * 1989-05-19 1995-06-15 Hayashibara Biochem Lab Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.
JP2832848B2 (ja) * 1989-10-21 1998-12-09 株式会社林原生物化学研究所 結晶2―O―α―D―グルコピラノシル―L―アスコルビン酸とその製造方法並びに用途

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DK0398484T3 (da) 1995-07-24
DE69019779T2 (de) 1995-12-14
US5137723A (en) 1992-08-11
EP0398484A3 (de) 1991-02-27
EP0398484A2 (de) 1990-11-22
US5616611A (en) 1997-04-01
US5767149A (en) 1998-06-16
EP0398484B1 (de) 1995-05-31
HK111196A (en) 1996-07-05
ES2075148T3 (es) 1995-10-01
DE69019779D1 (de) 1995-07-06

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