ATE119898T1 - Nmda-blockierende verbindungen, pharmazeutische präparate, deren herstellung und verwendung. - Google Patents
Nmda-blockierende verbindungen, pharmazeutische präparate, deren herstellung und verwendung.Info
- Publication number
- ATE119898T1 ATE119898T1 AT90312147T AT90312147T ATE119898T1 AT E119898 T1 ATE119898 T1 AT E119898T1 AT 90312147 T AT90312147 T AT 90312147T AT 90312147 T AT90312147 T AT 90312147T AT E119898 T1 ATE119898 T1 AT E119898T1
- Authority
- AT
- Austria
- Prior art keywords
- designates
- preparation
- chained
- straight
- nmda
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000003254 radicals Chemical class 0.000 abstract 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- 206010029350 Neurotoxicity Diseases 0.000 abstract 1
- 206010044221 Toxic encephalopathy Diseases 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000007135 neurotoxicity Effects 0.000 abstract 1
- 231100000228 neurotoxicity Toxicity 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL9223889A IL92238A (en) | 1989-11-07 | 1989-11-07 | ADMN blocking product containing tetrahydrocannabinol history, several new tetrahydrocannabinol histories and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE119898T1 true ATE119898T1 (de) | 1995-04-15 |
Family
ID=11060554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90312147T ATE119898T1 (de) | 1989-11-07 | 1990-11-06 | Nmda-blockierende verbindungen, pharmazeutische präparate, deren herstellung und verwendung. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0427518B1 (de) |
| JP (1) | JPH0768235B2 (de) |
| KR (1) | KR950005914B1 (de) |
| AT (1) | ATE119898T1 (de) |
| AU (1) | AU631262B2 (de) |
| CA (1) | CA2029419C (de) |
| DE (1) | DE69017839T2 (de) |
| DK (1) | DK0427518T3 (de) |
| ES (1) | ES2071786T3 (de) |
| IL (1) | IL92238A (de) |
| ZA (1) | ZA908914B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6017903A (en) | 1996-09-27 | 2000-01-25 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors |
| US5824662A (en) | 1996-09-27 | 1998-10-20 | Guilford Pharmaceuticals Inc. | Treatment of global and focal ischemia using naaladase inhibitors |
| PL332413A1 (en) | 1996-09-27 | 1999-09-13 | Guilford Pharm Inc | Compositions containing inhibitors of naaladase as well as methods of treating glutamatic anomaly and influencing neuronic functions among animals |
| DE19706903A1 (de) | 1997-02-21 | 1998-08-27 | Bayer Ag | Verwendung von bekannten Agonisten des zentralen Cannabinoid-Rezeptors CB 1 |
| IL132784A (en) * | 1997-05-07 | 2004-07-25 | Unimed Pharmaceutical Inc | Pharmaceutical compositions containing dronabinol |
| US6630507B1 (en) | 1998-04-21 | 2003-10-07 | The United States Of America As Represented By The Department Of Health And Human Services | Cannabinoids as antioxidants and neuroprotectants |
| NZ601567A (en) | 2005-09-29 | 2013-03-28 | Albany Molecular Res Inc | Process for production of delta-9-tetrahydrocannabinol |
| DE102015112092B4 (de) | 2015-07-24 | 2022-03-10 | Beko Technologies Gmbh | Öl/Wasser-Trennvorrichtung mit Druckluftbeaufschlagung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL48824A (en) * | 1976-01-12 | 1980-05-30 | Yissum Res Dev Co | Pharmaceutical compositions containing (3s,js) tetrahydrocanabinol derivatives and some novel compounds of this type |
| US4133819A (en) * | 1977-06-17 | 1979-01-09 | Pfizer Inc. | Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents |
| US4209520A (en) * | 1977-06-17 | 1980-06-24 | Pfizer Inc. | Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents |
| IL80411A (en) * | 1986-10-24 | 1991-08-16 | Raphael Mechoulam | Preparation of dibenzopyranol derivatives and pharmaceutical compositions containing them |
-
1989
- 1989-11-07 IL IL9223889A patent/IL92238A/en not_active IP Right Cessation
-
1990
- 1990-11-06 DE DE69017839T patent/DE69017839T2/de not_active Expired - Fee Related
- 1990-11-06 EP EP90312147A patent/EP0427518B1/de not_active Expired - Lifetime
- 1990-11-06 ES ES90312147T patent/ES2071786T3/es not_active Expired - Lifetime
- 1990-11-06 AU AU65834/90A patent/AU631262B2/en not_active Ceased
- 1990-11-06 DK DK90312147.3T patent/DK0427518T3/da active
- 1990-11-06 AT AT90312147T patent/ATE119898T1/de not_active IP Right Cessation
- 1990-11-07 ZA ZA908914A patent/ZA908914B/xx unknown
- 1990-11-07 CA CA002029419A patent/CA2029419C/en not_active Expired - Fee Related
- 1990-11-07 KR KR1019900018114A patent/KR950005914B1/ko not_active IP Right Cessation
- 1990-11-07 JP JP2302296A patent/JPH0768235B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2071786T3 (es) | 1995-07-01 |
| DK0427518T3 (da) | 1995-07-24 |
| AU6583490A (en) | 1991-05-30 |
| KR910009687A (ko) | 1991-06-28 |
| KR950005914B1 (ko) | 1995-06-07 |
| DE69017839T2 (de) | 1995-08-31 |
| JPH03209377A (ja) | 1991-09-12 |
| IL92238A0 (de) | 1990-07-26 |
| CA2029419C (en) | 2004-05-25 |
| AU631262B2 (en) | 1992-11-19 |
| IL92238A (en) | 1995-07-31 |
| JPH0768235B2 (ja) | 1995-07-26 |
| EP0427518B1 (de) | 1995-03-15 |
| EP0427518A1 (de) | 1991-05-15 |
| DE69017839D1 (de) | 1995-04-20 |
| CA2029419A1 (en) | 1991-05-08 |
| ZA908914B (en) | 1991-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |