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ATE119388T1 - Verfahren zur herstellung einer einen wärme-, licht- und feuchtigkeit empfindlichen wirkstoff mit einer monoklinisch kristallinen struktur enthaltenden tabletten oder dragee zusammensetzung. - Google Patents

Verfahren zur herstellung einer einen wärme-, licht- und feuchtigkeit empfindlichen wirkstoff mit einer monoklinisch kristallinen struktur enthaltenden tabletten oder dragee zusammensetzung.

Info

Publication number
ATE119388T1
ATE119388T1 AT91915256T AT91915256T ATE119388T1 AT E119388 T1 ATE119388 T1 AT E119388T1 AT 91915256 T AT91915256 T AT 91915256T AT 91915256 T AT91915256 T AT 91915256T AT E119388 T1 ATE119388 T1 AT E119388T1
Authority
AT
Austria
Prior art keywords
pct
tablets
moisture
composition containing
heat
Prior art date
Application number
AT91915256T
Other languages
English (en)
Inventor
Istvan Kovacs
Katalin Beke
Tibor Mate
Judit Szilagyi
Gyoergy Bacsa
Katalin Marossy
Sandor Jancs
Levente Szendrei
Erno Orban
Margit Simo
Margit Biblo
Dorottya Bobak
Jozsef Lango
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Application granted granted Critical
Publication of ATE119388T1 publication Critical patent/ATE119388T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Bending Of Plates, Rods, And Pipes (AREA)
  • Press Drives And Press Lines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT91915256T 1990-08-24 1991-08-23 Verfahren zur herstellung einer einen wärme-, licht- und feuchtigkeit empfindlichen wirkstoff mit einer monoklinisch kristallinen struktur enthaltenden tabletten oder dragee zusammensetzung. ATE119388T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU905314A HU206824B (en) 1990-08-24 1990-08-24 Process for the production of a table crystallizing in the monoclinic system, which contains light-, heat-, and moisture- sensitive active agents

Publications (1)

Publication Number Publication Date
ATE119388T1 true ATE119388T1 (de) 1995-03-15

Family

ID=10970061

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91915256T ATE119388T1 (de) 1990-08-24 1991-08-23 Verfahren zur herstellung einer einen wärme-, licht- und feuchtigkeit empfindlichen wirkstoff mit einer monoklinisch kristallinen struktur enthaltenden tabletten oder dragee zusammensetzung.

Country Status (19)

Country Link
US (1) US5322698A (de)
EP (1) EP0500851B1 (de)
JP (1) JPH0813736B2 (de)
KR (1) KR0177493B1 (de)
AT (1) ATE119388T1 (de)
CA (1) CA2067733C (de)
CZ (1) CZ281577B6 (de)
DE (1) DE69108007T2 (de)
DK (1) DK0500851T3 (de)
ES (1) ES2072617T3 (de)
FI (1) FI103015B1 (de)
GR (1) GR3015719T3 (de)
HU (1) HU206824B (de)
IL (1) IL99237A (de)
IN (1) IN171740B (de)
NO (1) NO303669B1 (de)
PT (1) PT98758B (de)
SK (1) SK278919B6 (de)
WO (1) WO1992003126A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5472714A (en) * 1993-09-08 1995-12-05 Ciba-Geigy Corporation Double-layered oxcarbazepine tablets
US5399356A (en) * 1994-03-24 1995-03-21 The Procter & Gamble Company Process for making solid dose forms containing bismuth
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6471994B1 (en) * 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US6395303B1 (en) * 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US6852336B2 (en) 1995-11-15 2005-02-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Directly compressible high load acetaminophen formulations
US5733578A (en) * 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6391337B2 (en) 1995-11-15 2002-05-21 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
ATE241341T1 (de) * 1997-09-10 2003-06-15 Takeda Chemical Industries Ltd Stabilisierte pharmazeutische zusammensetzung
GB9910505D0 (en) * 1999-05-06 1999-07-07 Electrosols Ltd A method and apparatus for manufacturing consumable tablets
ES2262528T3 (es) * 1999-08-04 2006-12-01 Astellas Pharma Inc. Composiciones medicinales estables para administracion oral que utilizan oxidos de hierro.
BR0113070A (pt) * 2000-08-10 2003-07-08 Unihart Corp Composições farmacêuticas contendo carbonato de lìtio

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907999A (en) * 1968-01-30 1975-09-23 Merck & Co Inc Substituted dibenzocyclooctene compositions
NL167153C (nl) * 1968-12-24 1981-11-16 Merck & Co Inc Werkwijze voor het bereiden of vervaardigen van een farmaceutisch preparaat en werkwijze voor het bereiden van een farmacologisch werkzaam, aan het stikstofatoom gesubstitueerd 5-aminomethyl-5-hydroxy-5h-dibenzoÿa.dÿ- cyclohepteen, geschikt voor gebruik bij de genoemde werkwijze.
DE2416903A1 (de) * 1974-04-06 1975-10-09 Bayer Ag Verwendung von schmelzverspruehtem kugelfoermigem phenacetingranulat zur herstellung von tabletten im direkttablettierverfahren
US4198402A (en) * 1975-12-17 1980-04-15 Richter Gedeon Vegyeszeti Gyar Rt. Antiphlogistic composition of phenylbutozone and alkali salicylate and method of treatment
EP0112061A3 (de) * 1982-11-20 1985-08-14 Beecham Group Plc Pharmazeutische und tierärztliche Guanoxabenz enthaltende Zusammensetzung
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
CA1261261A (en) * 1985-03-08 1989-09-26 Dev K. Mehra Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation
US4707361A (en) * 1985-08-02 1987-11-17 Stauffer Chemical Company Granular anhydrous dicalcium phosphate compositions suitable for direct compression tableting

Also Published As

Publication number Publication date
ES2072617T3 (es) 1995-07-16
HU206824B (en) 1993-01-28
JPH05503540A (ja) 1993-06-10
SK278919B6 (sk) 1998-04-08
HU905314D0 (en) 1991-02-28
NO303669B1 (no) 1998-08-17
PT98758B (pt) 1999-01-29
CS261791A3 (en) 1992-03-18
CZ281577B6 (cs) 1996-11-13
US5322698A (en) 1994-06-21
FI921809L (fi) 1992-04-23
NO921569L (no) 1992-04-23
IN171740B (de) 1992-12-26
CA2067733A1 (en) 1992-02-25
NO921569D0 (no) 1992-04-23
DE69108007T2 (de) 1995-07-20
JPH0813736B2 (ja) 1996-02-14
FI921809A0 (fi) 1992-04-23
KR927002214A (ko) 1992-09-03
PT98758A (pt) 1992-07-31
FI103015B (fi) 1999-04-15
CA2067733C (en) 2002-03-19
DE69108007D1 (de) 1995-04-13
IL99237A (en) 1996-01-19
WO1992003126A1 (en) 1992-03-05
EP0500851B1 (de) 1995-03-08
KR0177493B1 (ko) 1999-03-20
EP0500851A1 (de) 1992-09-02
DK0500851T3 (da) 1995-07-24
IL99237A0 (en) 1992-07-15
FI103015B1 (fi) 1999-04-15
GR3015719T3 (en) 1995-07-31

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Legal Events

Date Code Title Description
EEFA Change of the company name
EELA Cancelled due to lapse of time