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ATE119063T1 - Verbessertes verfahren und vorrichtung zur tangentiellen filtrierung. - Google Patents

Verbessertes verfahren und vorrichtung zur tangentiellen filtrierung.

Info

Publication number
ATE119063T1
ATE119063T1 AT91917291T AT91917291T ATE119063T1 AT E119063 T1 ATE119063 T1 AT E119063T1 AT 91917291 T AT91917291 T AT 91917291T AT 91917291 T AT91917291 T AT 91917291T AT E119063 T1 ATE119063 T1 AT E119063T1
Authority
AT
Austria
Prior art keywords
improved method
tangential filtration
flux
species
tangential
Prior art date
Application number
AT91917291T
Other languages
English (en)
Inventor
Reis Robert D Van
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE119063T1 publication Critical patent/ATE119063T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B01D61/146—Ultrafiltration comprising multiple ultrafiltration steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Cyclones (AREA)
  • Combined Means For Separation Of Solids (AREA)
AT91917291T 1990-09-17 1991-09-11 Verbessertes verfahren und vorrichtung zur tangentiellen filtrierung. ATE119063T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/583,886 US5256294A (en) 1990-09-17 1990-09-17 Tangential flow filtration process and apparatus

Publications (1)

Publication Number Publication Date
ATE119063T1 true ATE119063T1 (de) 1995-03-15

Family

ID=24334996

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91917291T ATE119063T1 (de) 1990-09-17 1991-09-11 Verbessertes verfahren und vorrichtung zur tangentiellen filtrierung.

Country Status (10)

Country Link
US (2) US5256294A (de)
EP (1) EP0552192B1 (de)
JP (2) JP3828143B2 (de)
AT (1) ATE119063T1 (de)
CA (1) CA2089663C (de)
DE (1) DE69107855T2 (de)
DK (1) DK0552192T3 (de)
ES (1) ES2072017T3 (de)
LV (1) LV11283B (de)
WO (1) WO1992004970A1 (de)

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EP0552192B1 (de) 1995-03-01
US5490937A (en) 1996-02-13
JPH06500730A (ja) 1994-01-27
DE69107855T2 (de) 1995-09-07
ES2072017T3 (es) 1995-07-01
JP3828143B2 (ja) 2006-10-04
CA2089663A1 (en) 1992-03-18
JP2003334425A (ja) 2003-11-25
EP0552192A1 (de) 1993-07-28
US5256294A (en) 1993-10-26
WO1992004970A1 (en) 1992-04-02
LV11283B (en) 1996-12-20
DE69107855D1 (de) 1995-04-06
DK0552192T3 (da) 1995-07-17
LV11283A (lv) 1996-06-20
CA2089663C (en) 2002-05-28

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