ATE106017T1 - Chemische verbindung. - Google Patents
Chemische verbindung.Info
- Publication number
- ATE106017T1 ATE106017T1 AT89907205T AT89907205T ATE106017T1 AT E106017 T1 ATE106017 T1 AT E106017T1 AT 89907205 T AT89907205 T AT 89907205T AT 89907205 T AT89907205 T AT 89907205T AT E106017 T1 ATE106017 T1 AT E106017T1
- Authority
- AT
- Austria
- Prior art keywords
- heating
- organic matter
- primary amine
- solubilized
- chemical compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
- 239000011707 mineral Substances 0.000 abstract 2
- 239000005416 organic matter Substances 0.000 abstract 2
- 125000002924 primary amino group Chemical class [H]N([H])* 0.000 abstract 2
- 238000005406 washing Methods 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000007857 degradation product Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/365—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/84—Bones; tendons; teeth; cartilage
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Materials For Medical Uses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888813033A GB8813033D0 (en) | 1988-06-02 | 1988-06-02 | Chemical compound |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE106017T1 true ATE106017T1 (de) | 1994-06-15 |
Family
ID=10637934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89907205T ATE106017T1 (de) | 1988-06-02 | 1989-06-02 | Chemische verbindung. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5167961A (de) |
EP (1) | EP0372066B1 (de) |
JP (1) | JP2679855B2 (de) |
AT (1) | ATE106017T1 (de) |
CA (1) | CA1339302C (de) |
DE (1) | DE68915518T2 (de) |
GB (1) | GB8813033D0 (de) |
WO (1) | WO1989011880A1 (de) |
Families Citing this family (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5236456A (en) * | 1989-11-09 | 1993-08-17 | Osteotech, Inc. | Osteogenic composition and implant containing same |
DE69304092T2 (de) * | 1992-02-10 | 1997-01-02 | Matsumoto Dental College Shioj | Knochenersatzwerkstoff und Verfahren zu seiner Herstellung |
US5565502A (en) * | 1993-03-24 | 1996-10-15 | Children's Medical Center Corporation | Isolation of the calcium-phosphate crystals of bone |
US5439951A (en) * | 1993-03-24 | 1995-08-08 | Children's Medical Center Corporation | Isolation of the calcium-phosphate crystals of bone |
AU7454694A (en) * | 1993-07-21 | 1995-02-20 | Faissol Pinto, Olympio | Process for preparing an osseous ceramic material and bone regenerating and growth promoting composition |
US5976104A (en) * | 1994-08-19 | 1999-11-02 | Lifenet Research Foundation | Recirculation method for cleaning essentially intact bone grafts using pressure mediated flow of solutions and bone grafts produced thereby |
US5797871A (en) * | 1994-08-19 | 1998-08-25 | Lifenet Research Foundation | Ultrasonic cleaning of allograft bone |
US5977034A (en) * | 1994-08-19 | 1999-11-02 | Lifenet Research Foundation | Composition for cleaning bones |
US5556379A (en) * | 1994-08-19 | 1996-09-17 | Lifenet Research Foundation | Process for cleaning large bone grafts and bone grafts produced thereby |
US7141072B2 (en) * | 1998-10-05 | 2006-11-28 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method for promoting regeneration of surface cartilage in a damaged joint using multi-layer covering |
US20050186673A1 (en) * | 1995-02-22 | 2005-08-25 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material, and method |
GB9503492D0 (en) * | 1995-02-22 | 1995-04-12 | Ed Geistlich S Hne A G F R Che | Chemical product |
US6206922B1 (en) | 1995-03-27 | 2001-03-27 | Sdgi Holdings, Inc. | Methods and instruments for interbody fusion |
US5730155A (en) * | 1995-03-27 | 1998-03-24 | Allen; Dillis V. | Ethmoidal implant and eyeglass assembly and its method of location in situ |
US5782919A (en) | 1995-03-27 | 1998-07-21 | Sdgi Holdings, Inc. | Interbody fusion device and method for restoration of normal spinal anatomy |
US5788976A (en) * | 1996-02-12 | 1998-08-04 | Wbk, Inc. | Method for effecting bone repair |
US6352558B1 (en) | 1996-02-22 | 2002-03-05 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method for promoting regeneration of surface cartilage in a damage joint |
US5940807A (en) * | 1996-05-24 | 1999-08-17 | Purcell; Daniel S. | Automated and independently accessible inventory information exchange system |
CA2263557C (en) * | 1996-09-10 | 2004-04-13 | Heinz Winkler | Implant consisting of a carrier material containing medical substances and method to produce such an implant |
US20050165483A1 (en) * | 2004-01-27 | 2005-07-28 | Ray Eddie F.Iii | Bone grafts |
DE19708782C1 (de) * | 1997-03-04 | 1998-08-06 | Claus Prof Dr Herdeis | Verfahren zur Herstellung von 2-Aminoethansulfonylazid-säureadditionssalzen, 2-Aminoethansulfonylazid-hydrochlorid sowie dessen Verwendung |
US5972368A (en) | 1997-06-11 | 1999-10-26 | Sdgi Holdings, Inc. | Bone graft composites and spacers |
US8858981B2 (en) * | 1997-10-10 | 2014-10-14 | Ed. Geistlich Soehne Fuer Chemistrie Industrie | Bone healing material comprising matrix carrying bone-forming cells |
US20050186283A1 (en) * | 1997-10-10 | 2005-08-25 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material, and method |
US20030180263A1 (en) * | 2002-02-21 | 2003-09-25 | Peter Geistlich | Resorbable extracellular matrix for reconstruction of bone |
US9034315B2 (en) * | 1997-10-10 | 2015-05-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Cell-charged multi-layer collagen membrane |
US6511509B1 (en) | 1997-10-20 | 2003-01-28 | Lifenet | Textured bone allograft, method of making and using same |
US5972933A (en) * | 1998-01-08 | 1999-10-26 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Method of treating microbial infections |
US6166007A (en) | 1998-07-02 | 2000-12-26 | Sodemann; Klaus | Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof |
US6206923B1 (en) * | 1999-01-08 | 2001-03-27 | Sdgi Holdings, Inc. | Flexible implant using partially demineralized bone |
US6113638A (en) * | 1999-02-26 | 2000-09-05 | Williams; Lytton A. | Method and apparatus for intervertebral implant anchorage |
AU3556400A (en) | 1999-03-17 | 2000-10-04 | Novartis Ag | Pharmaceutical compositions |
US7371408B1 (en) | 1999-06-07 | 2008-05-13 | Wright Medical Technology, Inc. | Bone graft substitute composition |
US6641571B2 (en) | 2000-01-05 | 2003-11-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery |
US20020004502A1 (en) | 2000-01-05 | 2002-01-10 | Redmond H. Paul | Treatment of inflammatory bowel disease |
DE10029520A1 (de) * | 2000-06-21 | 2002-01-17 | Merck Patent Gmbh | Beschichtung für metallische Implantatmaterialien |
US9387094B2 (en) | 2000-07-19 | 2016-07-12 | Warsaw Orthopedic, Inc. | Osteoimplant and method of making same |
DK177997B1 (da) * | 2000-07-19 | 2015-02-23 | Ed Geistlich Söhne Ag Für Chemische Ind | Knoglemateriale og collagenkombination til opheling af beskadigede led |
US20020114795A1 (en) * | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
CA2447683A1 (en) * | 2001-04-16 | 2002-10-24 | James J. Cassidy | Dense/porous structures for use as bone substitutes |
AU2002300450B2 (en) * | 2001-08-10 | 2007-04-05 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Collagen Carrier of Therapeutic Genetic Material, and Method |
US7371409B2 (en) | 2001-09-06 | 2008-05-13 | Wright Medical Technology, Inc. | Bone graft substitute composition |
CA2412012C (en) * | 2001-11-20 | 2011-08-02 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage |
US7708776B1 (en) | 2002-01-16 | 2010-05-04 | Nuvasive, Inc. | Intervertebral disk replacement system and methods |
EP1489998B1 (de) | 2002-03-29 | 2010-12-08 | Wright Medical Technology, Inc. | Knochentransplantat-ersatzzusammensetzung |
DE60334897D1 (de) * | 2002-03-30 | 2010-12-23 | Infinity Orthopaedics Co Ltd | Medizinische Intervertebrale Vorrichtung |
US7291179B2 (en) * | 2002-06-24 | 2007-11-06 | Wright Medical Technology, Inc. | Bone graft substitute composition |
US6652887B1 (en) | 2002-06-24 | 2003-11-25 | Wright Medical Technology, Inc. | Bone graft substitute composition |
EP1549359A2 (de) | 2002-10-08 | 2005-07-06 | Osteotech, Inc. | Kupplungsmittel für orthopädische biomaterialien |
US7507257B2 (en) * | 2003-02-04 | 2009-03-24 | Wright Medical Technology, Inc. | Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects |
JP2007503292A (ja) | 2003-06-11 | 2007-02-22 | オステオテック インコーポレーテッド | 骨インプラント及びその製造方法 |
US8012210B2 (en) * | 2004-01-16 | 2011-09-06 | Warsaw Orthopedic, Inc. | Implant frames for use with settable materials and related methods of use |
US20050266037A1 (en) * | 2004-05-25 | 2005-12-01 | Agency For Science, Technology & Research, A Comp. Organized & Existing Under The Laws Of Singapore | Implantable biomaterial and method for the preparation thereof |
US7250550B2 (en) * | 2004-10-22 | 2007-07-31 | Wright Medical Technology, Inc. | Synthetic bone substitute material |
US7696182B2 (en) | 2004-11-02 | 2010-04-13 | Nd Partners, Llc | Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin |
KR100635385B1 (ko) * | 2005-03-15 | 2006-10-17 | 재단법인서울대학교산학협력재단 | 프라이온-프리 골 이식 대체재의 제조방법 |
US8025903B2 (en) | 2005-09-09 | 2011-09-27 | Wright Medical Technology, Inc. | Composite bone graft substitute cement and articles produced therefrom |
CN103349793B (zh) | 2005-09-09 | 2016-02-10 | 阿格诺沃斯健康关爱公司 | 复合骨移植替代物水泥以及由其制得的制品 |
US7618459B2 (en) * | 2005-09-26 | 2009-11-17 | Infinity Orthopedics Ltd. | Universal spinal disc implant system |
GB2431408A (en) * | 2005-10-19 | 2007-04-25 | Osta Technologies Cc | Bone material and a process for the preparation of bone material |
WO2007084609A2 (en) * | 2006-01-19 | 2007-07-26 | Osteotech, Inc. | Porous osteoimplant |
CA2637616A1 (en) | 2006-01-19 | 2007-07-26 | Osteotech, Inc. | Injectable and moldable bone substitute materials |
WO2007132952A1 (en) * | 2006-05-12 | 2007-11-22 | Seoul National University Industry Foundation | Method for preparing a prion-free bone grafting substitute |
RU2468796C2 (ru) * | 2006-09-07 | 2012-12-10 | Эд. Гайстлих Зёне Аг Фюр Хемише Индустри | Способ лечения рака костей |
KR100842012B1 (ko) * | 2006-09-12 | 2008-06-27 | 재단법인서울대학교산학협력재단 | 말뼈를 이용한 골이식재의 제조방법 |
US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
EP2306913A4 (de) * | 2008-03-28 | 2014-06-04 | Warsaw Orthopedic Inc | Knochenanker für orthopädische anwendungen |
WO2012134540A2 (en) | 2010-10-22 | 2012-10-04 | Vanderbilt University | Injectable synthetic pur composite |
US9333276B2 (en) * | 2008-10-30 | 2016-05-10 | Vanderbilt University | Bone/polyurethane composites and methods thereof |
ES2402961T3 (es) | 2009-06-23 | 2013-05-10 | Geistlich Pharma Ag | Material sustitutivo del hueso |
PL2436342T3 (pl) | 2010-10-01 | 2013-09-30 | Geistlich Pharma Ag | Urządzenie do podawania materiału zamiennika kości |
CA2817584C (en) | 2010-11-15 | 2018-01-02 | Zimmer Orthobiologics, Inc. | Bone void fillers |
AU2011348430B2 (en) | 2010-12-22 | 2015-07-09 | Geistlich Pharma Ag | Bone substitute material |
US20150250921A1 (en) | 2011-09-29 | 2015-09-10 | Collagen Matrix, Inc. | Method of preparing porous carbonate apatite from natural bone |
US8980328B2 (en) | 2011-09-29 | 2015-03-17 | Collagen Matrix, Inc. | Method of preparing porous carbonate apatite from natural bone |
KR101295686B1 (ko) * | 2011-11-23 | 2013-08-14 | 충북대학교 산학협력단 | 조류 부리로부터 유래된 세라믹을 이용한 생체의료용 및 산업용 재료의 제조 방법 |
RU2478394C1 (ru) * | 2011-11-23 | 2013-04-10 | Федеральное государственное бюджетное учреждение "Российский научный центр "Восстановительная травматология и ортопедия" имени академика Г.А. Илизарова" Министерства здравоохранения и социального развития Российской Федерации | Биоматериал для возмещения дефектов костей и способ его получения |
US10071120B2 (en) | 2013-01-28 | 2018-09-11 | Warsaw Orthopedic, Inc. | Bone fiber compositions |
EP2826495A1 (de) | 2013-07-19 | 2015-01-21 | Geistlich Pharma AG | Biomimetisches Kollagen-Hydroxyapatit-Verbundmaterial |
BE1023728B1 (fr) * | 2013-10-03 | 2017-06-30 | Wishbone Sa | Materiau de regeneration osseuse et son procede de fabrication |
US9610381B2 (en) | 2013-10-08 | 2017-04-04 | Sigmagraft, Inc. | Process for extracting natural hydroxyaptite granules from bovine bone |
US9623153B2 (en) | 2014-09-23 | 2017-04-18 | Warsaw Orthopedic, Inc. | Bone graft materials and methods of use |
EP3217925B1 (de) | 2014-11-14 | 2025-04-02 | Warsaw Orthopedic, Inc. | Knochentransplantatmaterialien, vorrichtungen und verwendung |
US9839722B2 (en) | 2015-10-28 | 2017-12-12 | Warsaw Orthopedic, Inc. | Bone void filler having calcium coatings |
US10029031B2 (en) | 2015-10-28 | 2018-07-24 | Warsaw Orthopedic, Inc. | Bone void filler having sustained therapeutic agent release |
EP3175869A1 (de) | 2015-12-04 | 2017-06-07 | Geistlich Pharma AG | Vernetzte resorbierbare formstabile membran |
KR102328400B1 (ko) * | 2016-11-15 | 2021-11-18 | 한국재료연구원 | 코일 구조 세라믹을 포함하는 골충진재의 제조방법 및 이에 의하여 제조된 골충진재 |
EP3409303A1 (de) | 2017-06-02 | 2018-12-05 | Geistlich Pharma AG | Verwendung einer resorbierbaren vernetzten, formstabilen zusammensetzung zur herstellung einer membran |
MX2020006214A (es) | 2017-12-14 | 2020-08-31 | Geistlich Pharma Ag | Composicion de implante seco y formulacion de implante acuoso inyectable. |
MX2020005846A (es) | 2017-12-14 | 2020-09-07 | Geistlich Pharma Ag | Material de sustitucion osea. |
CN108578773B (zh) * | 2018-03-12 | 2021-02-12 | 南京航空航天大学 | 短流程制备多孔块状异种骨修复材料的方法和由该方法制得的骨修复材料 |
CN108653819B (zh) * | 2018-03-12 | 2021-02-12 | 南京航空航天大学 | 短流程制备多孔异种骨骨粉修复材料的方法和由该方法制得的骨修复材料 |
WO2020249714A1 (en) | 2019-06-14 | 2020-12-17 | Geistlich Pharma Ag | Collagen matrix or granulate blend of bone substitute material |
AU2020293633B2 (en) | 2019-06-14 | 2023-02-02 | Geistlich Pharma Ag | Collagen matrix or granulate blend of bone substitute material |
CA3141985C (en) | 2019-06-14 | 2023-12-05 | Geistlich Pharma Ag | Injectable aqueous implant formulation containing ascorbic acid |
RU2722266C1 (ru) * | 2019-09-13 | 2020-05-28 | федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр травматологии и ортопедии имени Р.Р. Вредена" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТО им. Р.Р. Вредена" Минздрава России) | Лиофилизированный биологический биодеградируемый минерализованный костнопластический материал и способ его изготовления |
TR202009080A2 (tr) * | 2020-06-11 | 2021-12-21 | Univ Yildiz Teknik | Hayvan kemiğinden ksenogreft üretimi. |
BE1030086B1 (fr) | 2021-12-23 | 2023-07-26 | Wishbone | Matériau de régénération osseuse |
US11738120B1 (en) | 2022-04-14 | 2023-08-29 | Cormedix Inc. | Synthesis of taurolidine, purity profiles and polymorphs |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2968593A (en) * | 1957-12-09 | 1961-01-17 | Armour & Co | Preparation of anorganic bone |
JPS574915A (en) * | 1980-06-10 | 1982-01-11 | Fujisawa Pharmaceut Co Ltd | Preparation of medical preparation with long-lasting activity |
US4455256A (en) * | 1981-05-05 | 1984-06-19 | The Regents Of The University Of California | Bone morphogenetic protein |
CA1190855A (en) * | 1980-09-03 | 1985-07-23 | Rolf W. Pfirrmann | Treatment of osteitis |
US4314380A (en) * | 1980-09-26 | 1982-02-09 | Koken Co., Ltd. | Artificial bone |
JPS5815016A (ja) * | 1981-07-15 | 1983-01-28 | Mitsubishi Mining & Cement Co Ltd | 動物の骨からリン酸カルシウム化合物を製造する方法 |
JPS5858041A (ja) * | 1981-10-05 | 1983-04-06 | 三菱鉱業セメント株式会社 | 骨欠損部及び空隙部充てん材 |
US4434094A (en) * | 1983-04-12 | 1984-02-28 | Collagen Corporation | Partially purified osteogenic factor and process for preparing same from demineralized bone |
DE3375073D1 (en) * | 1983-10-20 | 1988-02-11 | Oscobal Ag | Bone substitute material based on natural bone |
GB8328074D0 (en) * | 1983-10-20 | 1983-11-23 | Geistlich Soehne Ag | Chemical compositions |
US4596574A (en) * | 1984-05-14 | 1986-06-24 | The Regents Of The University Of California | Biodegradable porous ceramic delivery system for bone morphogenetic protein |
US4563350A (en) * | 1984-10-24 | 1986-01-07 | Collagen Corporation | Inductive collagen based bone repair preparations |
CA1260391A (en) * | 1985-03-28 | 1989-09-26 | Karl A. Piez | Xenogeneic collagen/mineral preparations in bone repair |
GB8514055D0 (en) * | 1985-06-04 | 1985-07-10 | Geistlich Soehne Ag | Chemical substance |
CA1294876C (en) * | 1986-04-22 | 1992-01-28 | Karl A. Piez | Marrow/collagen/mineral matrix for bone defect repair |
JPS63125258A (ja) * | 1986-11-14 | 1988-05-28 | 三菱マテリアル株式会社 | 骨欠損部、空隙部及び吸収部充てん材 |
DE3727606A1 (de) * | 1987-08-19 | 1989-05-03 | Aesculap Ag | Verfahren zur herstellung eines knochenersatzmaterials |
US4880610A (en) * | 1988-04-20 | 1989-11-14 | Norian Corporation | In situ calcium phosphate minerals--method and composition |
DE8901347U1 (de) * | 1989-02-07 | 1989-10-05 | FEMUK Labortechnik GmbH, 8100 Garmisch-Partenkirchen | Haltevorrichtung für Krückstöcke, insbesondere bei Krankenhausbetten |
-
1988
- 1988-06-02 GB GB888813033A patent/GB8813033D0/en active Pending
-
1989
- 1989-05-30 CA CA000601093A patent/CA1339302C/en not_active Expired - Lifetime
- 1989-06-02 WO PCT/GB1989/000618 patent/WO1989011880A1/en active IP Right Grant
- 1989-06-02 EP EP89907205A patent/EP0372066B1/de not_active Expired - Lifetime
- 1989-06-02 DE DE68915518T patent/DE68915518T2/de not_active Expired - Lifetime
- 1989-06-02 AT AT89907205T patent/ATE106017T1/de not_active IP Right Cessation
- 1989-06-02 US US07/460,177 patent/US5167961A/en not_active Expired - Lifetime
- 1989-06-02 JP JP1506707A patent/JP2679855B2/ja not_active Expired - Lifetime
-
1994
- 1994-01-04 US US08/178,431 patent/US5417975A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5417975A (en) | 1995-05-23 |
WO1989011880A1 (en) | 1989-12-14 |
US5167961A (en) | 1992-12-01 |
EP0372066B1 (de) | 1994-05-25 |
JP2679855B2 (ja) | 1997-11-19 |
CA1339302C (en) | 1997-08-19 |
GB8813033D0 (en) | 1988-07-06 |
DE68915518T2 (de) | 1994-09-08 |
DE68915518D1 (de) | 1994-06-30 |
EP0372066A1 (de) | 1990-06-13 |
JPH02504627A (ja) | 1990-12-27 |
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