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ATE104867T1 - Inhalationsgeraet fuer aerosolen. - Google Patents

Inhalationsgeraet fuer aerosolen.

Info

Publication number
ATE104867T1
ATE104867T1 AT8989309756T AT89309756T ATE104867T1 AT E104867 T1 ATE104867 T1 AT E104867T1 AT 8989309756 T AT8989309756 T AT 8989309756T AT 89309756 T AT89309756 T AT 89309756T AT E104867 T1 ATE104867 T1 AT E104867T1
Authority
AT
Austria
Prior art keywords
holding chamber
rigid holding
patient
flow meter
compact
Prior art date
Application number
AT8989309756T
Other languages
English (en)
Inventor
Bart Joseph Zoltan
Beth Louise Laube
George Kenneth Adams Iii
Clarke F Bow
Ralph J Devito
Walter Harrington
Louis S Hoffman
Charles B Sanders
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of ATE104867T1 publication Critical patent/ATE104867T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0096Hindering inhalation before activation of the dispenser

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT8989309756T 1988-10-04 1989-09-26 Inhalationsgeraet fuer aerosolen. ATE104867T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25303988A 1988-10-04 1988-10-04

Publications (1)

Publication Number Publication Date
ATE104867T1 true ATE104867T1 (de) 1994-05-15

Family

ID=22958578

Family Applications (1)

Application Number Title Priority Date Filing Date
AT8989309756T ATE104867T1 (de) 1988-10-04 1989-09-26 Inhalationsgeraet fuer aerosolen.

Country Status (7)

Country Link
US (1) US5027806A (de)
EP (1) EP0363060B1 (de)
JP (1) JP2927836B2 (de)
AT (1) ATE104867T1 (de)
CA (1) CA1327299C (de)
DE (1) DE68914932T2 (de)
ES (1) ES2051371T3 (de)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
DE4133274A1 (de) * 1991-08-22 1993-02-25 Boehringer Ingelheim Kg Vorrichtung zum atemzugsynchronen ausloesen eines mechanischen schaltvorganges
DE4027391A1 (de) * 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
WO1993000951A1 (en) * 1991-07-02 1993-01-21 Inhale, Inc. Method and device for delivering aerosolized medicaments
US5320094A (en) * 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US5318016A (en) * 1993-03-30 1994-06-07 We Pharmaceuticals, Inc. Inhalation device
US5752502A (en) * 1993-12-16 1998-05-19 King; Russell Wayne General purpose aerosol inhalation apparatus
SE502268C2 (sv) * 1994-01-26 1995-09-25 Aga Ab Sätt, användning och beredning av aerosol för läkemedelsdistribution innehållande helium och/eller neon
HUT75676A (en) 1994-03-07 1997-05-28 Inhale Therapeutic Syst Methods and compositions for pulmonary delivery of insulin
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
PL187750B1 (pl) 1994-09-21 2004-09-30 Nektar Therapeutics Sposób i urządzenie do wytwarzania aerozolu ze sproszkowanego leku
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
WO1998006426A1 (en) * 1996-08-14 1998-02-19 Gram Joergen Brodersen Use of a plasminogen activator for the treatment of pulmonary disorders
US5906202A (en) * 1996-11-21 1999-05-25 Aradigm Corporation Device and method for directing aerosolized mist to a specific area of the respiratory tract
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
US20030113271A1 (en) * 1997-01-29 2003-06-19 University Technology Corporation Formulations for pulmonary delivery
DE19734022C2 (de) * 1997-08-06 2000-06-21 Pari Gmbh Inhalationstherapiegerät mit einem Ventil zur Begrenzung des Inspirationsflusses
US5855564A (en) * 1997-08-20 1999-01-05 Aradigm Corporation Aerosol extrusion mechanism
NZ504021A (en) * 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
EP1047467B1 (de) * 1998-01-16 2004-06-23 1263152 Ontario Inc. Anzeigevorrichtung zur verwendung mit einer abgabevorrichtung
BR9908771A (pt) 1998-03-16 2000-12-12 Inhale Therapeutic Syst Processos para a liberação de um agente ativo e de insulina para os pulmões de um paciente humano, dispositivo para aumentar a biodisponibilidade de um agente ativo, e, dispositivos para a liberação de um agente ativo e de insulina para os pulmões de um paciente humano
US6082358A (en) 1998-05-05 2000-07-04 1263152 Ontario Inc. Indicating device for aerosol container
US6257233B1 (en) * 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
GB9825118D0 (en) * 1998-11-16 1999-01-13 Minnesota Mining & Mfg Breath-actuated aerosol dispensers
GB2344534B (en) * 1998-12-11 2000-10-18 Bespak Plc Inhalation apparatus
US6223744B1 (en) 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
AU2001234005B2 (en) * 2000-02-28 2006-01-19 Pharmakodex Limited Improvements in or relating to the delivery of oral drugs
US6453900B1 (en) * 2000-06-09 2002-09-24 Pulmonary Services, Inc. Inhaler device
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
US7004164B2 (en) 2002-03-21 2006-02-28 Trudell Medical International Indicating device for aerosol container
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
US7621273B2 (en) 2003-10-28 2009-11-24 Trudell Medical International Indicating device with warning dosage indicator
US7100530B2 (en) 2003-12-15 2006-09-05 Trudell Medical International, Inc. Dose indicating device
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
ES2543007T3 (es) 2004-08-23 2015-08-13 Mannkind Corporation Micropartículas que comprenden sales de dicetopiperazina para la administración de fármacos
US7543582B2 (en) 2004-09-20 2009-06-09 Trudell Medical International Dose indicating device with display elements attached to container
US7886934B2 (en) 2005-01-20 2011-02-15 Trudell Medical International Dispensing device
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
NZ591509A (en) 2005-05-18 2012-10-26 Mpex Pharmaceuticals Inc Taste masking of fluoroquinolones with a divalent or trivalent cation
WO2007033372A2 (en) 2005-09-14 2007-03-22 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
RU2403059C2 (ru) 2006-02-22 2010-11-10 Маннкайнд Корпорейшн Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент
US8141550B2 (en) 2006-08-01 2012-03-27 Trudell Medical International Dispensing device
PT2230934E (pt) 2007-12-14 2012-11-20 Aerodesigns Inc Distribuir produtos alimentares aerossolizáveis
SG192447A1 (en) * 2008-03-27 2013-08-30 Mannkind Corp A dry powder inhalation system
US8082873B2 (en) 2008-05-05 2011-12-27 Trudell Medical International Drive mechanism for an indicating device
US8181591B1 (en) 2008-05-23 2012-05-22 Trudell Medical International Domed actuator for indicating device
KR101933816B1 (ko) 2008-06-13 2019-03-29 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
WO2010008523A1 (en) 2008-07-13 2010-01-21 Map Pharmaceuticals, Inc. Methods and apparatus for delivering aerosolized medication
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
JP2012505223A (ja) 2008-10-07 2012-03-01 エムペックス・ファーマシューティカルズ・インコーポレーテッド 薬物動態の改善のためのエアゾールフルオロキノロン配合物
SI2346509T1 (sl) 2008-10-07 2020-08-31 Horizon Orphan Llc Inhalacija levofloksacina za zmanjšanje vnetja pljuč
ES2402241T3 (es) 2008-10-22 2013-04-30 Trudell Medical International Sistema de suministro de aerosol modular
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR20190090092A (ko) 2009-06-12 2019-07-31 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
SI2473170T1 (sl) 2009-09-04 2019-10-30 Horizon Orphan Llc Uporaba aerosoliziranega levofloksacina za zdravljenje cistične fibroze
EP2496295A1 (de) 2009-11-03 2012-09-12 MannKind Corporation Vorrichtung und verfahren zur simulation von einatmungsanstrengungen
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
DK2670242T3 (da) 2011-01-31 2022-05-02 Avalyn Pharma Inc Aerosolpirfenidon- og pyridonanalogforbindelser og anvendelser deraf
ES2625858T3 (es) 2011-04-01 2017-07-20 Mannkind Corporation Paquete de tipo blíster para cartuchos farmacéuticos
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US9233159B2 (en) 2011-10-24 2016-01-12 Mannkind Corporation Methods and compositions for treating pain
US9802012B2 (en) 2012-07-12 2017-10-31 Mannkind Corporation Dry powder drug delivery system and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (de) 2013-03-15 2019-08-21 MannKind Corporation Mikrokristalline diketopiperazinzusammensetzungen und verfahren
KR102321339B1 (ko) 2013-07-18 2021-11-02 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
CA2919498C (en) 2013-07-31 2023-07-25 Windward Pharma, Inc. Aerosol nintedanib compounds and uses thereof
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
NZ760541A (en) 2014-01-10 2022-08-26 Avalyn Pharma Inc Aerosol pirfenidone and pyridone analog compounds and uses thereof
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
WO2024134330A1 (en) * 2022-12-19 2024-06-27 G.D S.P.A Device for inhaling a product, in particular a pharmaceutical product

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US733027A (en) * 1903-02-28 1903-07-07 Frederick Tagliavia Tanini Inhaler.
US1695930A (en) * 1924-11-15 1928-12-18 Alexander Bernhard Drager Inhaling device for administering gases and the like
FR773018A (fr) * 1933-08-09 1934-11-10 Perfectionnements aux appareils inhalateurs de gaz ou vapeurs
DE1045049B (de) * 1953-11-24 1958-11-27 Dr Med Karl Seidl Inhalationsgeraet fuer gasfoermige Stoffe und zur Atemgymnastik
GB1479283A (en) * 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
US3960148A (en) * 1974-10-15 1976-06-01 Dryden Gale E Apparatus for high flow anesthesia
US4077404A (en) * 1975-09-17 1978-03-07 H. B. W. Medical Instruments Manufacturing Company, Inc. Breathing equipment such as resuscitators
US4534343A (en) * 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
FI69963C (fi) * 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
NZ209900A (en) * 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4790305A (en) * 1986-06-23 1988-12-13 The Johns Hopkins University Medication delivery system

Also Published As

Publication number Publication date
US5027806A (en) 1991-07-02
JP2927836B2 (ja) 1999-07-28
ES2051371T3 (es) 1994-06-16
EP0363060A2 (de) 1990-04-11
DE68914932D1 (de) 1994-06-01
JPH02243164A (ja) 1990-09-27
DE68914932T2 (de) 1994-08-11
CA1327299C (en) 1994-03-01
EP0363060A3 (de) 1991-01-02
EP0363060B1 (de) 1994-04-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee