ATA285187A - Substituierte alpha-aminosaeuren, ihre herstellung und diese enthaltende arzneimittel - Google Patents

Substituierte alpha-aminosaeuren, ihre herstellung und diese enthaltende arzneimittel

Info

Publication number: ATA285187A
Authority: AT; Austria
Prior art keywords: production; amino acids; products containing; alpha amino; medicinal products
Prior art date: 1986-10-30

Application number

AT2851/87A

Other languages

English (en)

Other versions

AT393384B (de

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-10-30

Filing date

1987-10-29

Publication date

1991-03-15

1987-10-29 Application filed by Sandoz Ag filed Critical Sandoz Ag

1991-03-15 Publication of ATA285187A publication Critical patent/ATA285187A/de

1991-10-10 Application granted granted Critical

1991-10-10 Publication of AT393384B publication Critical patent/AT393384B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3882—Arylalkanephosphonic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Anesthesiology (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT2851/87A 1986-10-30 1987-10-29 Substituierte alpha-aminosaeuren, ihre herstellung und diese enthaltende arzneimittel AT393384B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868625941A GB8625941D0 (en)	1986-10-30	1986-10-30	Substituted alpha-amino acids

Publications (2)

Publication Number	Publication Date
ATA285187A true ATA285187A (de)	1991-03-15
AT393384B AT393384B (de)	1991-10-10

Family

ID=10606531

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT2851/87A AT393384B (de)	1986-10-30	1987-10-29	Substituierte alpha-aminosaeuren, ihre herstellung und diese enthaltende arzneimittel

Country Status (27)

Country	Link
US (1)	US5162311A (de)
JP (2)	JPH0641475B2 (de)
KR (1)	KR950004960B1 (de)
AT (1)	AT393384B (de)
AU (1)	AU614726B2 (de)
BE (1)	BE1002421A4 (de)
CA (1)	CA1310331C (de)
CH (1)	CH677794A5 (de)
CY (1)	CY1703A (de)
DE (1)	DE3736016C2 (de)
DK (1)	DK565987A (de)
ES (1)	ES2012521A6 (de)
FI (1)	FI87222C (de)
FR (1)	FR2606018B1 (de)
GB (2)	GB8625941D0 (de)
GR (1)	GR871659B (de)
HK (1)	HK110393A (de)
HU (1)	HU200465B (de)
IE (1)	IE59310B1 (de)
IL (1)	IL84302A (de)
IT (1)	IT1212033B (de)
LU (1)	LU87031A1 (de)
NL (1)	NL8702485A (de)
NZ (1)	NZ222333A (de)
PT (1)	PT86018B (de)
SE (1)	SE466311B (de)
ZA (1)	ZA878176B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5395827A (en) *	1986-04-09	1995-03-07	Guilford Pharmaceuticals Inc.	ω-[2-(phosphonoalkyl)phenyl]-2-aminoalkanoic acids as antagonists of excitatory amino acid receptors
US4918064A (en) *	1987-10-21	1990-04-17	G. D. Searle & Co.	Phenyl glycines for use in reducing neurotoxic injury
US5175153A (en) *	1987-11-30	1992-12-29	Warner-Lambert Company	Substituted alpha-amino acids having pharmaceutical activity
FR2634763B1 (fr) *	1988-08-01	1991-07-12	Inst Nat Sante Rech Med	Amino-acides et peptides presentant un residu tyrosine modifiee, leur preparation et leur application comme medicaments
US4997821A (en) *	1988-10-21	1991-03-05	Cordi Alexis A	Phosphono-hydroisoquinoline compounds useful in reducing neurotoxic injury
US5177240A (en) *	1988-10-21	1993-01-05	G. D. Searle & Co.	O-phosphono(alkyl)-n-sulfonyl-phenyl-alanine derivatives useful as intermediates for preparation of phosphono-hydroisoquinolines
US5100654A (en) *	1989-04-07	1992-03-31	Yale University	Phosphorylated derivatives of l-dopa and compositions and methods for increasing the melanin content in mammalian skin and hair
DE3940410A1 (de) *	1989-12-04	1991-06-06	Schering Ag	Neue verwendung von nmda-rezeptor-antagonisten
US5238958A (en) *	1990-02-26	1993-08-24	Warner-Lambert Company	Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals
US5086072A (en) *	1990-06-18	1992-02-04	The United States Of America As Represented By The Department Of Health And Human Services	Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
US5475129A (en) *	1991-09-30	1995-12-12	The United States Of America As Represented By The Department Of Health And Human Services	Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis
US5264607A (en) *	1991-09-30	1993-11-23	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Process of making benzylic α,α-diflurophosphonates from benzylic α-ketophosphorates
US5200546A (en) *	1991-09-30	1993-04-06	The United States Of America As Represented By The Department Of Health And Human Services	Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis
GB9325360D0 (en) *	1993-12-10	1994-02-16	Univ Bristol	Organic compounds
US5489717A (en) *	1994-07-08	1996-02-06	Warner-Lambert Company	Glutamate (NMDA) receptor antagonists
GB9423019D0 (en) *	1994-11-15	1995-01-04	Sandoz Ltd	Improvements in or relating to organic compounds
US5922697A (en) *	1996-10-02	1999-07-13	Warner-Lambert Company	Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins
US6133281A (en) *	1996-10-24	2000-10-17	Harbor-Ucla Research And Education Institute	NMDA receptor blockers in the therapy of urogenital disease
EP1009407B1 (de) *	1997-09-04	2004-04-28	Novoneuron, Inc.	Noribogain zur behandlung von schmerzen und drogenabhängigkeit
MY153569A (en) *	1998-01-20	2015-02-27	Mitsubishi Tanabe Pharma Corp	Inhibitors of ?4 mediated cell adhesion
SE9804064D0 (sv) *	1998-11-25	1998-11-25	A & Science Invest Ab	Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells
MY140707A (en) *	2002-02-28	2010-01-15	Mitsubishi Tanabe Pharma Corp	Process for preparing a phenylalanine derivative and intermediates thereof
DE10328260A1 (de) *	2003-06-23	2005-01-27	Schmidt, K.-G., Dr. med.	Flupirtine-Präparat
EP1754483A1 (de) *	2005-08-18	2007-02-21	Merck Sante	Verwendung von Thienopyridonederivativen als AMPK Aktivatoren und pharmazeutische Zusammensetzungen, die diese enthalten
JP2013534914A (ja)	2010-06-09	2013-09-09	クイーンマリーアンドウエストフィールドカレッジ、ユニバーシティオブロンドン	アネキシン１抗体
GB201121564D0 (en) *	2011-12-14	2012-01-25	Queen Mary & Westfield College	Use of antibody
GB201702091D0 (en)	2017-02-08	2017-03-22	Medannex Ltd	Specific binding molecules
EP3427729A1 (de)	2017-07-13	2019-01-16	Paris Sciences et Lettres - Quartier Latin	Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE550634A (de) *	1955-08-30
BE626546A (de) *	1961-12-30
DE2459491A1 (de) *	1974-12-17	1976-06-24	Bayer Ag	Gegenueber isocyanaten reaktive phosphorhaltige flammschutzmittel
US4657899A (en) *	1986-04-09	1987-04-14	Nova Pharmaceutical Corporation	Antagonists of specific excitatory amino acid neurotransmitter receptors
US4761405A (en) *	1987-03-04	1988-08-02	Nova Pharmaceutical Corporation	Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency
US4918064A (en) *	1987-10-21	1990-04-17	G. D. Searle & Co.	Phenyl glycines for use in reducing neurotoxic injury

1986
- 1986-10-30 GB GB868625941A patent/GB8625941D0/en active Pending
1987
- 1987-10-15 GB GB8724186A patent/GB2198134B/en not_active Expired - Lifetime
- 1987-10-16 NL NL8702485A patent/NL8702485A/nl active Search and Examination
- 1987-10-16 HU HU874665A patent/HU200465B/hu not_active IP Right Cessation
- 1987-10-23 CH CH4169/87A patent/CH677794A5/de not_active IP Right Cessation
- 1987-10-23 DE DE3736016A patent/DE3736016C2/de not_active Expired - Fee Related
- 1987-10-26 FR FR878714891A patent/FR2606018B1/fr not_active Expired - Lifetime
- 1987-10-26 BE BE8701221A patent/BE1002421A4/fr not_active IP Right Cessation
- 1987-10-28 NZ NZ222333A patent/NZ222333A/xx unknown
- 1987-10-28 AU AU80404/87A patent/AU614726B2/en not_active Ceased
- 1987-10-28 SE SE8704204A patent/SE466311B/sv not_active IP Right Cessation
- 1987-10-28 DK DK565987A patent/DK565987A/da not_active Application Discontinuation
- 1987-10-28 PT PT86018A patent/PT86018B/pt not_active IP Right Cessation
- 1987-10-28 IT IT8748544A patent/IT1212033B/it active
- 1987-10-28 LU LU87031A patent/LU87031A1/fr unknown
- 1987-10-28 IL IL84302A patent/IL84302A/xx not_active IP Right Cessation
- 1987-10-29 CA CA000550571A patent/CA1310331C/en not_active Expired - Lifetime
- 1987-10-29 GR GR871659A patent/GR871659B/el unknown
- 1987-10-29 JP JP62274594A patent/JPH0641475B2/ja not_active Expired - Lifetime
- 1987-10-29 FI FI874761A patent/FI87222C/fi not_active IP Right Cessation
- 1987-10-29 IE IE290887A patent/IE59310B1/en not_active IP Right Cessation
- 1987-10-29 AT AT2851/87A patent/AT393384B/de not_active IP Right Cessation
- 1987-10-29 KR KR1019870011983A patent/KR950004960B1/ko not_active IP Right Cessation
- 1987-10-30 ZA ZA878176A patent/ZA878176B/xx unknown
- 1987-10-30 ES ES8703112A patent/ES2012521A6/es not_active Expired - Lifetime
1990
- 1990-08-02 JP JP2206678A patent/JPH03101685A/ja active Pending
1991
- 1991-08-19 US US07/747,177 patent/US5162311A/en not_active Expired - Fee Related
1993
- 1993-10-21 HK HK1103/93A patent/HK110393A/xx not_active IP Right Cessation
1994
- 1994-01-14 CY CY170394A patent/CY1703A/xx unknown

Also Published As

Publication number	Publication date
CH677794A5 (de)	1991-06-28
PT86018A (en)	1987-11-01
AU614726B2 (en)	1991-09-12
CA1310331C (en)	1992-11-17
FR2606018B1 (fr)	1990-11-16
JPH0641475B2 (ja)	1994-06-01
ZA878176B (en)	1989-06-28
GB2198134A (en)	1988-06-08
US5162311A (en)	1992-11-10
JPS63122693A (ja)	1988-05-26
NZ222333A (en)	1990-09-26
FI874761A0 (fi)	1987-10-29
DK565987D0 (da)	1987-10-28
FI87222C (fi)	1992-12-10
DE3736016A1 (de)	1988-05-05
JPH03101685A (ja)	1991-04-26
KR950004960B1 (ko)	1995-05-16
BE1002421A4 (fr)	1991-02-05
FR2606018A1 (fr)	1988-05-06
FI874761A (fi)	1988-05-01
IL84302A0 (en)	1988-03-31
GB8724186D0 (en)	1987-11-18
KR890006661A (ko)	1989-06-15
IT8748544A0 (it)	1987-10-28
GR871659B (en)	1988-03-03
DK565987A (da)	1988-05-01
FI87222B (fi)	1992-08-31
GB2198134B (en)	1990-07-04
DE3736016C2 (de)	1995-04-20
IT1212033B (it)	1989-11-08
PT86018B (pt)	1990-07-31
ES2012521A6 (es)	1990-04-01
AT393384B (de)	1991-10-10
IE59310B1 (en)	1994-02-09
SE8704204L (sv)	1988-05-01
AU8040487A (en)	1988-05-05
NL8702485A (nl)	1988-05-16
HUT47949A (en)	1989-04-28
LU87031A1 (fr)	1988-05-03
CY1703A (en)	1994-01-14
GB8625941D0 (en)	1986-12-03
SE8704204D0 (sv)	1987-10-28
IL84302A (en)	1993-06-10
IE872908L (en)	1988-04-30
HU200465B (en)	1990-06-28
SE466311B (sv)	1992-01-27
HK110393A (en)	1993-10-29

Publication	Publication Date	Title
ATA285187A (de)	1991-03-15	Substituierte alpha-aminosaeuren, ihre herstellung und diese enthaltende arzneimittel
DE3751845D1 (de)	1996-07-25	Stabilisiertes Arzneimittel und dessen Herstellung
DE3780329D1 (de)	1992-08-20	Chinoloncarbonsaeure-derivate und ihre herstellung.
ATE124951T1 (de)	1995-07-15	Fluorcytidinderivate, deren herstellung und arzneimittel, die diese derivate enthalten.
DE3782751D1 (de)	1993-01-07	Hydroxylaminderivate, deren herstellung und verwendung fuer heilmittel.
DE3780223D1 (de)	1992-08-13	Arzneimittel mit gesteuerter freisetzung.
DE3580616D1 (de)	1991-01-03	Mitomycinderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
AT388913B (de)	1989-09-25	Neue n-(2'-aminophenyl)-benzamid-derivate und arzneimittel, die diese enthalten
DE3785684D1 (de)	1993-06-09	Pyrrolidinamid-derivate von acylaminosaeure, pharmazeutische zusammensetzung und verwendung.
DE3771146D1 (de)	1991-08-08	Pyrimidinderivate, ihre herstellung und medikamente, die diese derivate enthalten.
DE3670639D1 (de)	1990-05-31	Neue biphosphonische abkoemmlinge, deren herstellung und arzneimittelzubereitung.
DE3685604D1 (de)	1992-07-16	1,7-naphthyridinderivate und diese enthaltende arzneimittel.
ATE40826T1 (de)	1989-03-15	4'-demethyl-4-epipodophyllotoxinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3876913D1 (de)	1993-02-04	Herstellung von kohlenstoffhaltigen pulvern und ihre granulierung.
DE68901859D1 (de)	1992-07-23	2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung.
DE3782112D1 (de)	1992-11-12	Pyrimidinderivate, deren herstellung und arzneimittel, die diese derivate enthalten.
DK103987A (da)	1987-09-12	Substituerede 1,3,4,9-tetrahydropyranooe3,4-baaindol-l-eddikesyrer, deres fremstilling og anvendelse som laegemidler
ATA36788A (de)	1990-03-15	Piperazincarbonsaeure, ihre herstellung und diese enthaltende arzneimittel
DE59002899D1 (de)	1993-11-04	Aromatische carbonsaeureamide, ihre herstellung und verwendung fuer heilmittel.
DE3578597D1 (de)	1990-08-16	4-phenylphthalazin-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
ATE32882T1 (de)	1988-03-15	Phenylnonatetraensaeurederivate, ihre herstellung und pharmazeutische praeparate mit diesen derivaten.
DE3786927D1 (de)	1993-09-09	Antithrombotische arzneimittel und deren herstellung.
DE3676360D1 (de)	1991-02-07	Nitroderivate von vinblastintyp-bis-indolen, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
IT1211681B (it)	1989-11-03	Peptidi e derivati peptidici, loro preparazione e loro impiego come medicamenti
DE3761379D1 (de)	1990-02-15	1,3-propandiaminderivate, ihre herstellung und sie enthaltende arzneimittel.

Legal Events

Date	Code	Title	Description
1999-11-15	ELJ	Ceased due to non-payment of the annual fee