AT379390B - Verfahren zur herstellung von neuen chinolonverbindungen - Google Patents
Verfahren zur herstellung von neuen chinolonverbindungenInfo
- Publication number
- AT379390B AT379390B AT0161880A AT161880A AT379390B AT 379390 B AT379390 B AT 379390B AT 0161880 A AT0161880 A AT 0161880A AT 161880 A AT161880 A AT 161880A AT 379390 B AT379390 B AT 379390B
- Authority
- AT
- Austria
- Prior art keywords
- chinolon
- compounds
- producing new
- producing
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0185084A AT380238B (de) | 1979-03-27 | 1984-06-05 | Verfahren zur herstellung von neuen chinolonverbindungen |
AT185184A AT380239B (de) | 1980-03-26 | 1984-06-05 | Verfahren zur herstellung von neuen chinolonverbindungen |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7910558 | 1979-03-27 | ||
GB7939505 | 1979-11-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA161880A ATA161880A (de) | 1985-05-15 |
AT379390B true AT379390B (de) | 1985-12-27 |
Family
ID=26271029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0161880A AT379390B (de) | 1979-03-27 | 1980-03-26 | Verfahren zur herstellung von neuen chinolonverbindungen |
Country Status (34)
Country | Link |
---|---|
US (1) | US4302460A (de) |
KR (1) | KR840001612B1 (de) |
AT (1) | AT379390B (de) |
AU (1) | AU536616B2 (de) |
BG (2) | BG37993A3 (de) |
CA (1) | CA1151652A (de) |
CH (1) | CH644366A5 (de) |
CS (1) | CS221906B2 (de) |
DD (1) | DD149608A5 (de) |
DE (2) | DE3011994A1 (de) |
DK (1) | DK151252C (de) |
EG (1) | EG16606A (de) |
FI (1) | FI77026C (de) |
FR (2) | FR2452484A1 (de) |
GR (1) | GR68007B (de) |
HK (1) | HK94986A (de) |
HU (1) | HU179845B (de) |
IE (1) | IE49562B1 (de) |
IL (1) | IL59710A (de) |
IT (1) | IT1188916B (de) |
KE (1) | KE3649D (de) |
LU (1) | LU82295A1 (de) |
MX (1) | MX6816E (de) |
MY (1) | MY8600668A (de) |
NL (1) | NL191306C (de) |
NO (1) | NO156787C (de) |
NZ (1) | NZ193167A (de) |
PH (1) | PH16758A (de) |
PL (1) | PL124037B1 (de) |
PT (1) | PT71006A (de) |
RO (1) | RO79397A (de) |
SE (1) | SE455422B (de) |
SG (1) | SG60886G (de) |
YU (1) | YU42332B (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE51542B1 (en) * | 1980-09-26 | 1987-01-07 | Boots Co Ltd | Therapeutic agents |
PT79031B (en) * | 1983-08-20 | 1986-08-22 | Boots Co Plc | Therapeutic agents |
DE3578374D1 (de) * | 1984-01-13 | 1990-08-02 | Boots Co Ltd | Verwendung von chinolonen fuer die herstellung eines arzneimittels zur behandlung von herzerkrankungen. |
EP0172004B1 (de) * | 1984-08-15 | 1990-03-21 | The Boots Company PLC | Chinolinone, Verfahren zu ihrer Herstellung und die sie enthaltenden pharmazeutischen Präparate |
GB8515209D0 (en) * | 1985-06-15 | 1985-07-17 | Boots Co Plc | Therapeutic agents |
GB8515207D0 (en) * | 1985-06-15 | 1985-07-17 | Boots Co Plc | Therapeutic agents |
GB8627698D0 (en) * | 1986-11-20 | 1986-12-17 | Boots Co Plc | Therapeutic agents |
GB8726950D0 (en) * | 1987-11-18 | 1987-12-23 | Boots Co Plc | Chemical process |
GB8804016D0 (en) * | 1988-02-22 | 1988-03-23 | Boots Co Plc | Therapeutic agents |
GB8918952D0 (en) * | 1989-08-19 | 1989-10-04 | Boots Co Plc | Therapeutic agents |
IL100555A (en) * | 1991-02-07 | 2000-08-31 | Hoechst Marion Roussel Inc | N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them |
FR2672597B1 (fr) * | 1991-02-07 | 1995-05-19 | Roussel Uclaf | Nouveaux derives n-substitues de la quinoleine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
FR2684671B1 (fr) * | 1991-11-20 | 1995-05-19 | Roussel Uclaf | Nouveaux derives de la quinoleine, leur procede de preparation et intermediaires et leur application a titre de medicaments. |
FR2680511B1 (fr) * | 1991-08-20 | 1995-05-19 | Roussel Uclaf | Derives n-substitues de la quinoleine, leur procede de preparation, intermediaires obtenus, leur application comme medicaments et les compositions les renfermant. |
WO2000007595A1 (en) * | 1998-08-03 | 2000-02-17 | Basf Corporation | Pyridinones for the treatment of sexual dysfunction |
US6307050B1 (en) * | 2000-08-29 | 2001-10-23 | R. T. Alamo Venture I Llc | Method of synthesizing flosequinan from 4-fluoroanthranilic acid |
US6458804B1 (en) * | 2001-01-26 | 2002-10-01 | R.T. Alamo Venturesi, Llc | Methods for the treatment of central nervous system disorders in certain patient groups |
US6451813B1 (en) | 2001-01-26 | 2002-09-17 | R. T. Alamo Ventures I, Llc | Treatment of gastroparesis in certain patient groups |
US6562838B2 (en) * | 2001-01-26 | 2003-05-13 | R. T. Alamo Ventures I, L.L.C. | Treatment of cardiovascular disease with quinolinone enantiomers |
US6649764B2 (en) * | 2001-10-25 | 2003-11-18 | R. T. Alamo Ventures I, Llc | Stereospecific enrichment of heterocyclic enantiomers |
US6730790B2 (en) * | 2002-03-01 | 2004-05-04 | R.T. Alamo Ventures I. Llc | Chlorinated heterocyclic compounds and methods of synthesis |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3178348A (en) * | 1961-02-08 | 1965-04-13 | Norwich Pharma Co | Hypotensive quinolines |
BE661965A (de) | 1964-04-03 | 1965-10-04 | ||
DE1770482A1 (de) * | 1968-05-22 | 1971-11-11 | Basf Ag | Verfahren zur Herstellung von 2,4-Dioxychinolinen |
US3798219A (en) * | 1971-10-18 | 1974-03-19 | Warner Lambert Co | 3-(methylsulfinyl)cinnolinones and their derivatives |
US3772301A (en) * | 1971-11-22 | 1973-11-13 | Warner Lambert Co | (4-substituted)4-(methylsulfinyl)methylcarbostyrils |
CH607848A5 (de) * | 1974-06-04 | 1978-11-30 | Bayer Ag | |
GB1488411A (en) * | 1975-01-16 | 1977-10-12 | Wyeth John & Brother Ltd | 3,4-dihydro-4-arylquinolin-4-ol derivatives |
US4127574A (en) * | 1976-03-01 | 1978-11-28 | Sandoz, Inc. | 4-Hydroxy-3-sulfonyl-quinolin-2(1H)-ones |
US4124587A (en) * | 1976-03-01 | 1978-11-07 | Sandoz, Inc. | 4-Hydroxy-3-sulfinyl-quinolin-2(1H)-ones |
DE2616991A1 (de) | 1976-04-17 | 1977-10-27 | Bayer Ag | Heterocyclisch-substituierte schwefelhaltige dihydropyridine, mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE2616995A1 (de) | 1976-04-17 | 1977-10-27 | Bayer Ag | 1.4-dihydropyridine mit schwefelhaltigen substituenten mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE2639257A1 (de) | 1976-09-01 | 1978-03-02 | Bayer Ag | Aminoalkylidenamino-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE2639498A1 (de) | 1976-09-02 | 1978-03-09 | Bayer Ag | Neue schwefelhaltige amino-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE2641746C2 (de) | 1976-09-16 | 1986-11-06 | Bayer Ag, 5090 Leverkusen | 1,4-Dihydropyridin-Zuckerderivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
DE2658183A1 (de) | 1976-12-22 | 1978-07-06 | Bayer Ag | In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE2658804A1 (de) | 1976-12-24 | 1978-07-06 | Bayer Ag | Kreislaufbeeinflussende mittel |
DE2715182A1 (de) | 1977-04-05 | 1978-10-19 | Bayer Ag | 2-alkylenaminodihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
US4177278A (en) * | 1977-04-05 | 1979-12-04 | Bayer Aktiengesellschaft | 2-Alkyleneaminodihydropyridines compounds, their production and their medicinal use |
JPS5424882A (en) * | 1977-07-22 | 1979-02-24 | Yamanouchi Pharmaceut Co Ltd | Novel heterocyclic compounds and their preparation |
DE2747513A1 (de) | 1977-10-22 | 1979-05-03 | Bayer Ag | Dihydropyridine mit schwefelhaltigen estergruppierungen |
-
1980
- 1980-03-18 NZ NZ193167A patent/NZ193167A/en unknown
- 1980-03-19 IE IE567/80A patent/IE49562B1/en not_active IP Right Cessation
- 1980-03-21 AU AU56702/80A patent/AU536616B2/en not_active Ceased
- 1980-03-22 GR GR61514A patent/GR68007B/el unknown
- 1980-03-24 US US06/133,310 patent/US4302460A/en not_active Expired - Lifetime
- 1980-03-24 PH PH23802A patent/PH16758A/en unknown
- 1980-03-25 IL IL59710A patent/IL59710A/xx not_active IP Right Cessation
- 1980-03-25 PT PT71006A patent/PT71006A/pt not_active IP Right Cessation
- 1980-03-25 FI FI800923A patent/FI77026C/fi not_active IP Right Cessation
- 1980-03-25 LU LU82295A patent/LU82295A1/fr unknown
- 1980-03-25 RO RO80100611A patent/RO79397A/ro unknown
- 1980-03-26 NO NO800881A patent/NO156787C/no unknown
- 1980-03-26 BG BG066170A patent/BG37993A3/xx unknown
- 1980-03-26 DK DK130180A patent/DK151252C/da not_active IP Right Cessation
- 1980-03-26 IT IT48262/80A patent/IT1188916B/it active
- 1980-03-26 AT AT0161880A patent/AT379390B/de not_active IP Right Cessation
- 1980-03-26 CA CA000348520A patent/CA1151652A/en not_active Expired
- 1980-03-26 BG BG047135A patent/BG37836A3/xx unknown
- 1980-03-26 SE SE8002345A patent/SE455422B/sv not_active IP Right Cessation
- 1980-03-26 KR KR1019800001266A patent/KR840001612B1/ko active
- 1980-03-26 NL NL8001771A patent/NL191306C/xx not_active IP Right Cessation
- 1980-03-26 CH CH237680A patent/CH644366A5/fr not_active IP Right Cessation
- 1980-03-26 YU YU849/80A patent/YU42332B/xx unknown
- 1980-03-26 HU HU8080713A patent/HU179845B/hu not_active IP Right Cessation
- 1980-03-27 DE DE19803011994 patent/DE3011994A1/de active Granted
- 1980-03-27 MX MX808725U patent/MX6816E/es unknown
- 1980-03-27 PL PL1980223050A patent/PL124037B1/pl unknown
- 1980-03-27 CS CS802156A patent/CS221906B2/cs unknown
- 1980-03-27 FR FR8006811A patent/FR2452484A1/fr active Granted
- 1980-03-27 DE DE19803051205 patent/DE3051205C2/de not_active Expired - Lifetime
- 1980-03-27 DD DD80219973A patent/DD149608A5/de not_active IP Right Cessation
- 1980-03-29 EG EG188/80A patent/EG16606A/xx active
- 1980-10-02 FR FR8021107A patent/FR2468367A1/fr active Granted
-
1986
- 1986-07-08 KE KE3649BD patent/KE3649D/xx unknown
- 1986-07-10 SG SG608/86A patent/SG60886G/en unknown
- 1986-12-04 HK HK949/86A patent/HK94986A/xx not_active IP Right Cessation
- 1986-12-30 MY MY668/86A patent/MY8600668A/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee | ||
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties | ||
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |