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AR119972A2 - BSPECIFIC ANTIGEN-BINDING MOLECULES ACTIVATING T-CELLS - Google Patents

BSPECIFIC ANTIGEN-BINDING MOLECULES ACTIVATING T-CELLS

Info

Publication number
AR119972A2
AR119972A2 ARP200102559A ARP200102559A AR119972A2 AR 119972 A2 AR119972 A2 AR 119972A2 AR P200102559 A ARP200102559 A AR P200102559A AR P200102559 A ARP200102559 A AR P200102559A AR 119972 A2 AR119972 A2 AR 119972A2
Authority
AR
Argentina
Prior art keywords
binding molecules
antigen
cells
bspecific
bispecific antigen
Prior art date
Application number
ARP200102559A
Other languages
Spanish (es)
Inventor
Oliver Ast
Marina Bacac
Sabine Imhof-Jung
Christiane Jaeger
Christian Klein
Stefan Klosterman
Michael Molhoj
Joerg Thomas Regula
Wolfgang Schaefer
Pablo Umaa
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR119972A2 publication Critical patent/AR119972A2/en

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente se refiere de manera general a moléculas biespecíficas de unión a antígeno para la activación de células T y redireccionamiento a células diana específicas. Además, la presente se refiere a polinucleótidos codificantes de dichas moléculas biespecíficas de unión a antígeno y a vectores y células huésped que comprenden dichos polinucleótidos. La presente se refiere además a métodos para producir las moléculas biespecíficas de unión a antígeno de la presente y a métodos de utilización de dichas moléculas biespecíficas de unión a antígeno en el tratamiento de enfermedades.This relates generally to bispecific antigen-binding molecules for T cell activation and redirection to specific target cells. Furthermore, the present invention relates to polynucleotides encoding said bispecific antigen-binding molecules and to vectors and host cells comprising said polynucleotides. This further relates to methods of producing the present bispecific antigen-binding molecules and to methods of using such bispecific antigen-binding molecules in the treatment of disease.

ARP200102559A 2014-08-04 2020-09-15 BSPECIFIC ANTIGEN-BINDING MOLECULES ACTIVATING T-CELLS AR119972A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14179764 2014-08-04

Publications (1)

Publication Number Publication Date
AR119972A2 true AR119972A2 (en) 2022-01-26

Family

ID=51260790

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP150102482A AR101409A1 (en) 2014-08-04 2015-08-03 BISPECIFIC MOLECULES OF ANTIGEN BINDING TO T-CELL ACTIVATORS
ARP200102559A AR119972A2 (en) 2014-08-04 2020-09-15 BSPECIFIC ANTIGEN-BINDING MOLECULES ACTIVATING T-CELLS

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP150102482A AR101409A1 (en) 2014-08-04 2015-08-03 BISPECIFIC MOLECULES OF ANTIGEN BINDING TO T-CELL ACTIVATORS

Country Status (1)

Country Link
AR (2) AR101409A1 (en)

Also Published As

Publication number Publication date
AR101409A1 (en) 2016-12-14

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