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AR109893A1 - Formas cristalinas de darunavir - Google Patents

Formas cristalinas de darunavir

Info

Publication number
AR109893A1
AR109893A1 ARP170102977A ARP170102977A AR109893A1 AR 109893 A1 AR109893 A1 AR 109893A1 AR P170102977 A ARP170102977 A AR P170102977A AR P170102977 A ARP170102977 A AR P170102977A AR 109893 A1 AR109893 A1 AR 109893A1
Authority
AR
Argentina
Prior art keywords
darunavir
formula
crystal forms
napsilate
silate
Prior art date
Application number
ARP170102977A
Other languages
English (en)
Inventor
Bing Shi
Chiajen Lai
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of AR109893A1 publication Critical patent/AR109893A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reivindicación 1: Un compuesto seleccionado del grupo que consiste en: Forma I de Darunavir (Forma I de la fórmula [1]); Darunavir Hidratado (Hidrato I de la fórmula [1]); Darunavir Solvatado (Solvato de Ácido Acético I de la fórmula [1]); Esilato de Darunavir (Esilato I de la fórmula [1]); Besilato de Darunavir (Besilato I de la fórmula [1]); Hemisulfato de Darunavir (Hemisulfato I de la fórmula [1]); Napsilato de Darunavir (Napsilato I de la fórmula [1]); Hemiedisilato de Darunavir (Hemiedisilato I de la fórmula [1]); y Tosilato de Darunavir (Tosilato I de la fórmula [1]).
ARP170102977A 2016-10-27 2017-10-26 Formas cristalinas de darunavir AR109893A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662413601P 2016-10-27 2016-10-27

Publications (1)

Publication Number Publication Date
AR109893A1 true AR109893A1 (es) 2019-01-30

Family

ID=60263147

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP170102977A AR109893A1 (es) 2016-10-27 2017-10-26 Formas cristalinas de darunavir

Country Status (6)

Country Link
US (1) US10407438B2 (es)
EP (1) EP3532478B1 (es)
AR (1) AR109893A1 (es)
ES (1) ES2881949T3 (es)
TW (1) TW201828946A (es)
WO (1) WO2018081292A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2881949T3 (es) 2016-10-27 2021-11-30 Gilead Sciences Inc Forma cristalina de base libre de darunavir
CN109053753A (zh) * 2018-08-05 2018-12-21 浙江大学 一种制备达卢那韦二水合物晶型的方法

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Also Published As

Publication number Publication date
TW201828946A (zh) 2018-08-16
ES2881949T3 (es) 2021-11-30
EP3532478B1 (en) 2021-05-26
US20180170945A1 (en) 2018-06-21
EP3532478A1 (en) 2019-09-04
US10407438B2 (en) 2019-09-10
WO2018081292A1 (en) 2018-05-03

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