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AR072531A1 - SENAL DE POLIADENILACIoN - Google Patents

SENAL DE POLIADENILACIoN

Info

Publication number
AR072531A1
AR072531A1 ARP090102796A ARP090102796A AR072531A1 AR 072531 A1 AR072531 A1 AR 072531A1 AR P090102796 A ARP090102796 A AR P090102796A AR P090102796 A ARP090102796 A AR P090102796A AR 072531 A1 AR072531 A1 AR 072531A1
Authority
AR
Argentina
Prior art keywords
regulatory elements
polyadenilation
sign
addition
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ARP090102796A
Other languages
English (en)
Inventor
Barbara Enenkel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of AR072531A1 publication Critical patent/AR072531A1/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Elementos reguladores así como a vectores y células relacionadas. Además, métodos de mejora de la expresion de polipéptidos a partir de ácidos nucleicos tales como genes clonados y a la produccion de diversos polipéptidos en células hospedadoras usando dichos elementos reguladores. Además, usos de dichos elementos reguladores como aislantes, en terapia génica o para líneas celulares hospedadoras. Kit.
ARP090102796A 2008-07-23 2009-07-22 SENAL DE POLIADENILACIoN Pending AR072531A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08161029 2008-07-23

Publications (1)

Publication Number Publication Date
AR072531A1 true AR072531A1 (es) 2010-09-01

Family

ID=40085605

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090102796A Pending AR072531A1 (es) 2008-07-23 2009-07-22 SENAL DE POLIADENILACIoN

Country Status (25)

Country Link
US (2) US8466271B2 (es)
EP (1) EP2310501B1 (es)
JP (1) JP5481478B2 (es)
KR (1) KR101837925B1 (es)
CN (1) CN102165060B (es)
AR (1) AR072531A1 (es)
AU (1) AU2009273239B2 (es)
BR (1) BRPI0915989A2 (es)
CA (1) CA2724908C (es)
CY (1) CY1114483T1 (es)
DK (1) DK2310501T3 (es)
EA (1) EA201100225A1 (es)
ES (1) ES2421152T3 (es)
HK (1) HK1156663A1 (es)
HR (1) HRP20130888T1 (es)
IL (1) IL208700A (es)
MX (1) MX2011000535A (es)
MY (1) MY156855A (es)
NZ (1) NZ589268A (es)
PL (1) PL2310501T3 (es)
PT (1) PT2310501E (es)
SG (2) SG188882A1 (es)
SI (1) SI2310501T1 (es)
TW (1) TW201011104A (es)
WO (1) WO2010010107A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009273239B2 (en) 2008-07-23 2015-07-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Novel regulatory elements
KR100882240B1 (ko) * 2008-09-11 2009-02-25 (주)플러스텍 질화물 반도체 발광소자 및 제조방법
WO2014102101A1 (en) 2012-12-31 2014-07-03 Boehringer Ingelheim International Gmbh Novel intron sequences
EP2938726B1 (en) 2012-12-31 2017-09-27 Boehringer Ingelheim International GmbH Heterologous intron within a signal peptide
CN104293737B (zh) * 2014-09-16 2017-06-13 太原博奥特生物技术有限公司 一种包含表达功能性重组人凝血因子ⅶ载体的宿主细胞及其高水平表达方法
KR102618127B1 (ko) 2016-09-20 2023-12-27 베링거잉겔하임베트메디카게엠베하 개 아데노바이러스 벡터
JP7187448B2 (ja) 2016-09-20 2022-12-12 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 新しいプロモーター
CA3036291A1 (en) 2016-09-20 2018-03-29 Boehringer Ingelheim Vetmedica Gmbh New ehv insertion site orf70
UY37408A (es) 2016-09-20 2018-03-23 Boehringer Ingelheim Vetmedica Gmbh Vacuna de vectores contra el virus de la gripe “a” porcina
GB201706121D0 (en) * 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Stable cell lines for retroviral production
JP2020517238A (ja) * 2017-04-18 2020-06-18 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ アデノ随伴ウイルスベクターの産生方法
AR113124A1 (es) 2017-09-23 2020-01-29 Boehringer Ingelheim Vetmedica Gmbh Sistema de expresión de paramyxoviridae
AU2019223768A1 (en) 2018-02-23 2020-08-27 Boehringer Ingelheim Animal Health USA Inc. Recombinant viral vector systems expressing exogenous feline paramyxovirus genes and vaccines made therefrom
EA202092165A1 (ru) 2018-03-19 2021-02-25 Бёрингер Ингельхайм Ветмедика Гмбх Новый ehv сайт инсерции ul43
MX2020009724A (es) 2018-03-19 2020-10-08 Boehringer Ingelheim Vetmedica Gmbh Ehv novedoso con ul18 y/o ul8 inactivados.
TW202026010A (zh) 2018-09-20 2020-07-16 德商百靈佳殷格翰維美迪加股份有限公司 抗豬流行性下痢之鼻內載體疫苗
CN109486859A (zh) * 2018-11-21 2019-03-19 新乡医学院 人工合成的polyA、哺乳动物细胞重组表达载体、哺乳动物宿主细胞、表达方法及应用
JP2023509443A (ja) * 2019-12-31 2023-03-08 スワンバイオ セラピューティクス リミテッド 改善されたａａｖ－ａｂｃｄ１コンストラクトならびに副腎白質ジストロフィー（ａｌｄ）および／または副腎脊髄ニューロパチー（ａｍｎ）の処置または予防のための使用
WO2022101679A1 (en) 2020-11-13 2022-05-19 Boehringer Ingelheim Vetmedica Gmbh New feline herpes virus vaccine
WO2024220672A2 (en) * 2023-04-18 2024-10-24 Siren Biotechnology, Inc. Adeno-associated viral vector compositions and methods of use
WO2024238890A1 (en) * 2023-05-18 2024-11-21 Decibel Therapeutics, Inc. Compositions and methods for treating gjb2-related hearing loss

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0173552B1 (en) 1984-08-24 1991-10-09 The Upjohn Company Recombinant dna compounds and the expression of polypeptides such as tpa
FR2629098B1 (fr) * 1988-03-23 1990-08-10 Rhone Poulenc Agrochimie Gene chimerique de resistance herbicide
US7351813B2 (en) * 2000-06-20 2008-04-01 The Board Of Trustees Of The Leland Stanford Junior University Liver-specific gene expression cassettes, and methods of use
UY26317A1 (es) * 2000-08-30 2000-10-31 Alfonso Cayota Carlos Pritsch Sistema de produccion de trombopoyetina humana por celulas de mamiferos en cultivo
KR101234981B1 (ko) 2003-10-10 2013-02-21 파우더젝트 백신, 인코포레이티드 핵산 구조물
US7557197B2 (en) * 2004-01-28 2009-07-07 Oregon Health & Science University Human soluble neuropilin-1 primary polyadenylation signal and uses thereof
PE20070500A1 (es) 2005-05-19 2007-06-17 Schering Ag Tratamiento de enfermedades usando un sistema mejorado de expresion regulada
AU2009273239B2 (en) 2008-07-23 2015-07-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Novel regulatory elements

Also Published As

Publication number Publication date
CN102165060B (zh) 2013-07-17
SG188882A1 (en) 2013-04-30
AU2009273239B2 (en) 2015-07-23
CA2724908C (en) 2017-03-14
AU2009273239A1 (en) 2010-01-28
EP2310501B1 (en) 2013-07-03
PT2310501E (pt) 2013-07-18
NZ589268A (en) 2012-06-29
TW201011104A (en) 2010-03-16
SG192541A1 (en) 2013-08-30
MX2011000535A (es) 2011-02-22
US20130177943A1 (en) 2013-07-11
CN102165060A (zh) 2011-08-24
SI2310501T1 (sl) 2013-10-30
ES2421152T3 (es) 2013-08-29
JP5481478B2 (ja) 2014-04-23
WO2010010107A1 (en) 2010-01-28
EP2310501A1 (en) 2011-04-20
EA201100225A1 (ru) 2011-08-30
IL208700A0 (en) 2010-12-30
PL2310501T3 (pl) 2013-12-31
HK1156663A1 (en) 2012-06-15
MY156855A (en) 2016-04-15
BRPI0915989A2 (pt) 2019-03-26
HRP20130888T1 (hr) 2013-10-25
KR20110031912A (ko) 2011-03-29
IL208700A (en) 2013-12-31
JP2011526795A (ja) 2011-10-20
KR101837925B1 (ko) 2018-03-13
US8975391B2 (en) 2015-03-10
US20110312029A1 (en) 2011-12-22
CY1114483T1 (el) 2016-10-05
CA2724908A1 (en) 2010-01-28
US8466271B2 (en) 2013-06-18
DK2310501T3 (da) 2013-08-26

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