[go: up one dir, main page]

AR066310A1 - Derivados de 4-aza indol y su uso como fungicidas - Google Patents

Derivados de 4-aza indol y su uso como fungicidas

Info

Publication number
AR066310A1
AR066310A1 ARP080101767A ARP080101767A AR066310A1 AR 066310 A1 AR066310 A1 AR 066310A1 AR P080101767 A ARP080101767 A AR P080101767A AR P080101767 A ARP080101767 A AR P080101767A AR 066310 A1 AR066310 A1 AR 066310A1
Authority
AR
Argentina
Prior art keywords
optionally substituted
pyrrolo
pyridin
pyridine
heterocyclyl
Prior art date
Application number
ARP080101767A
Other languages
English (en)
Original Assignee
Syngenta Ltd
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Ltd, Syngenta Participations Ag filed Critical Syngenta Ltd
Publication of AR066310A1 publication Critical patent/AR066310A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Proceso para la preparacion de un compuesto de formula (1) y composicion que lo comprende. Reivindicacion 1: Un método de prevencion y/o control de la infeccion fungica en las plantas y/o material de propagacion de plantas que comprende aplicar alas plantas o material de propagacion de plantas una cantidad efectiva como fungicida de un compuesto de la formula (1), donde: X1 es N o CH; X2 es N o CR5; R1 y R2 son independientemente, (i) hidrogeno, halogeno, hidroxilo, ciano o nitro, (ii)alquilo, alquenilo o alquinilo opcionalmente sustituido, (iii) arilo, heteroarilo, ciclilo o heterociclilo opcionalmente sustituido, o (iv) -C(O)R10, -C(O)NR10R11, -C(S)NR10R11, -C(NOR10)R11, -C(O)OR10, -OR10, -SR10, -S(O)R10, -S(O)NR10R11, -S(O)2R10, -NR10R11, -P(O)(OR10)(OR11) u -OP(O)(OR10)(OR11); R3 es: (i) hidrogeno, hidroxilo, ciano o nitro, (ii) alquilo, alquenilo, alenilo, alquinilo o haloalquilo opcionalmente sustituido, (iii) arilo, heteroarilo, ciclilo o heterociclilo oheteroaralquilo opcionalmente sustituido, o (iv) -C(O)R12, -C(O)OR12, -OR12, -OC(O)R12, -S(O)2R12 o -NR12R13; R4 es: (i) hidrogeno, halogeno, hidroxilo, ciano o nitro, (ii) alquenilo, alenilo, alquinilo o haloalquilo opcionalmente sustituido, (iii)arilo, heteroarilo, ciclilo o heterociclilo opcionalmente sustituido o (iv) -C(O)R14, -C(O)OR14 -C(NOR14)R15, -OR14, -SR14, -S(O)NR14R15, -S(O)2R14 o -NR14R15; R5 es: (i) hidrogeno, halogeno, hidroxilo, ciano o nitro, (ii) alquilo, alquenilo oalquinilo opcionalmente sustituido, (iii) -C(O)R16, -C(O)OR16, -OR16, -SR16, -S(O)R16, -S(O)NR16R17, -S(O)2R16 o -NR16R17; R6 es H, halogeno, ciano, -C(O)OR18, -SR18, -NR18R19, -C(O)NR18R19, -N=CR20, -C(=NR18)NR19R20 o arilo, heteroarilo, ciclilo oheterociclilo opcionalmente sustituido; R7 y R8 son, independientemente, hidrogeno, halogeno, hidroxilo, ciano, nitro, -NR21R22 o alquilo opcionalmente sustituido; R10, R11, R14, R15, R16 y R17 son, independientemente, hidrogeno, halogeno,hidroxilo, ciano, nitro, alquilo, alcoxi, alquenilo o alquinilo opcionalmente sustituido, o arilo, heteroarilo, ciclilo o heterociclilo opcionalmente sustituido; R12 y R13 son, independientemente, hidrogeno, halogeno, hidroxilo, ciano, nitro, -NR21R22, alquilo, alcoxi, alquenilo o alquinilo opcionalmente sustituido, o arilo, heteroarilo, ciclilo o heterociclilo opcionalmente sustituido; R18 y R19 son independientemente, (i) hidrogeno, (ii) alquilo, alquenilo o alquinilo opcionalmentesustituido, (iii) arilo, heteroarilo, ciclilo o heterociclilo opcionalmente sustituido, o (iv) -C(S)R23, -C(O)R23, -SO2R23, -C(O)OR23, -OR23 o -C(O)NR23R24; R20 es hidroxilo, alquilo o alcoxi opcionalmente sustituido, -NR21R22 o -N=CR21R22; R21 yR22 son, independientemente, hidrogeno, alquilo, alquenilo o alquinilo opcionalmente sustituido, ciclilo, heterociclilo, arilo o heteroarilo o aralquilo opcionalmente sustituido o -C(O)OR25; R23 y R24 son, independientemente, hidrogeno, hidroxilo,alquilo, alquenilo o alquinilo opcionalmente sustituido, o arilo, heteroarilo, ciclilo o heterociclilo o aralquilo opcionalmente sustituido; y R25 es alquilo, alquenilo o alquinilo opcionalmente sustituido; y/o independientemente, (i) R1 y R2, (ii)R1 y R3 (iii) R2 y R3, (iv) R3 y R5, (v) R5 y R6, (vi) R5 y R18, (vii) R5 y R19, (viii) R14 y R15 y (ix) R18 y R19 forman un grupo arilo, heteroarilo, ciclilo o heterociclilo opcionalmente sustituido que contiene de 5 a 18 átomos en el anillo; o unasal de N-oxido del mismo. Reivindicacion 19: Un compuesto de la formula (1) segun se definio en cualquiera de las reivindicaciones 1 a 17, con las condiciones de que (i) cuando X1 sea CH, X2 sea CR5 y R5 y R6 sean ambos H, R4 no sea 4-fluorfeniloy (ii) el compuesto de la formula (1) no sea: 3-fenil-2-piridin-4-il-1H-pirrolo[3,2-b)piridina, 3-(3-cloro-4-fluor-fenil)-2-piridin-4-il-1H-pirrolo[3,2-b]piridina, 3-(3-cloro-fenil)-2-piridin-4-il-1H-pirrolo[3,2-b]piridina, 3-(3-trifluor-fenil)-2-piridin-4-il-1H-pirrolo[3,2-b]piridina, 3-(3-metoxi-fenil)-2-piridin-4-il-1H-pirrolo[3,2-b)piridina, 3-(2-metilfenil)-2-piridin-4-il-1H-pirrolo[3,2-b]piridina, 3-(2-metoxifenil-2-piridin-4-il-1H-pirrolo[3,2-b]piridina, 1-metil-2-piridin-4-il-3-(3-trifluormetil-fenil)-1H-pirrolo[3,2-b]piridina, 1-metil-3-(3-cloro-4-fluor-fenil)-2-piridin-4-il-1H-pirrolo[3,2-b]piridina, 3-(4-fluorfenil-2-(2-(2-hidroxietil-amino)-piridin-4-i-1H-pirrolo[3,2-b]piridina, 3-(4-fluorfenil)-2-(2-[HO(CH2)2O(CH2)2NH]-piridin-4-il)-1H-pirrolo[3,2-b]piridina, 3-(4-fluorfenil)-2-(2-(2-metilamino-etilamino)-piridin-4-il)-1H-pirrolo[3,2-b]piridina, 3-(4-fluorfenil-2-(2-(3-metoxi-propil-amino)-piridin-4-il)-1H-pirrolo[3,2-b]piridina, 3-(4-fluorfenil)-2-(2-n-propilamino-piridin-4-il)-1H-pirrolo[3,2-b]piridina, 3-(4-fluorfenil)-2-(2-(3-hidroxi-propil-amino)-piridin-4-il)-1H-pirrolo[3,2-b]piridina, 3-(4-fluorfenil-2-(2-metilamino-piridin-4-il)-1H-pirrolo[3,2-b]piridina o 3-(4-fluorfenil)-2-(2-acetilaminopiridin-4-il)-1H-pirrolo[3,2-b]piridina. Reivindicacion 24: Un compuesto de la formula (1) segun se definio en el método de cualquiera de las reivindicaciones 1 a 17 para el tratamiento de la infeccion fungica en humanos o animales.
ARP080101767A 2007-04-26 2008-04-25 Derivados de 4-aza indol y su uso como fungicidas AR066310A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0708141.7A GB0708141D0 (en) 2007-04-26 2007-04-26 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
AR066310A1 true AR066310A1 (es) 2009-08-12

Family

ID=38170765

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080101767A AR066310A1 (es) 2007-04-26 2008-04-25 Derivados de 4-aza indol y su uso como fungicidas

Country Status (20)

Country Link
US (1) US8084395B2 (es)
EP (1) EP2136640A2 (es)
JP (1) JP2010525039A (es)
KR (1) KR20100015918A (es)
CN (1) CN101784191A (es)
AR (1) AR066310A1 (es)
AU (1) AU2008244055A1 (es)
BR (1) BRPI0810679A2 (es)
CA (1) CA2682773A1 (es)
CL (1) CL2008001214A1 (es)
CO (1) CO6140003A2 (es)
CR (1) CR11076A (es)
EC (1) ECSP099699A (es)
GB (1) GB0708141D0 (es)
IL (1) IL201195A0 (es)
MX (1) MX2009011337A (es)
RU (1) RU2009143567A (es)
TW (1) TW200847926A (es)
WO (1) WO2008132434A2 (es)
ZA (1) ZA200906887B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE541845T1 (de) * 2007-08-29 2012-02-15 Schering Corp 2,3-substituierte azaindolderivate zur behandlung von virusinfektionen
WO2010046215A2 (en) * 2008-10-21 2010-04-29 Syngenta Participations Ag Diaza-indole derivatives and their use as fungicides
DE102008052943A1 (de) * 2008-10-23 2010-04-29 Merck Patent Gmbh Azaindolderivate
EP2198710A1 (de) 2008-12-19 2010-06-23 Bayer CropScience AG Verwendung von 5-Pyridin-4yl-(1,3)Thiazole zur Bekämpfung phytopathogener Pilze
EP2417133A1 (en) * 2009-04-06 2012-02-15 PTC Therapeutics, Inc. Compounds and methods for antiviral treatment
EP2245936A1 (en) 2009-04-27 2010-11-03 Bayer CropScience AG Use of 4-aza indole derivatives for the reduction of mycotoxin contamination
AR081810A1 (es) 2010-04-07 2012-10-24 Bayer Cropscience Ag Piridinilpirazoles biciclicos
TW201242962A (en) 2010-12-01 2012-11-01 Sumitomo Chemical Co Pyrimidine compound and use for pest control thereof
WO2012084678A1 (en) * 2010-12-23 2012-06-28 Syngenta Participations Ag Novel imidazoles useful as plant fungicides
EP2487159A1 (en) 2011-02-11 2012-08-15 MSD Oss B.V. RorgammaT inhibitors
WO2012142452A2 (en) 2011-04-13 2012-10-18 Biosafe Technologies, Inc. Cleaning, insecticide, insect repellant, glue solvent and anti-irritation composition
CN103159663B (zh) * 2011-12-09 2014-09-17 中国科学院大连化学物理研究所 一种由联二烯衍生物制备吡咯衍生物的方法
WO2014026327A1 (en) 2012-08-15 2014-02-20 Merck Sharp & Dohme Corp. 4-heteroaryl substituted benzoic acid compounds as rorgammat inhibitors and uses thereof
WO2014026329A1 (en) 2012-08-15 2014-02-20 Merck Sharp & Dohme Corp. N-alkylated indole and indazole compounds as rorgammat inhibitors and uses thereof
WO2014026330A1 (en) 2012-08-15 2014-02-20 Merck Sharp & Dohme Corp. 3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
JP2016135742A (ja) * 2013-03-29 2016-07-28 日本農薬株式会社 縮合複素環化合物又はその塩類及び該化合物を含有する農園芸用殺虫剤並びにその使用方法
SI3049417T1 (sl) * 2013-07-31 2019-03-29 Merck Patent Gmbh Piridini, pirimidini in pirazini kot inhibitorji BTK in njihove uporabe
AR103232A1 (es) * 2014-12-22 2017-04-26 Bristol Myers Squibb Co ANTAGONISTAS DE TGFbR
WO2016130818A1 (en) 2015-02-11 2016-08-18 Merck Sharp & Dohme Corp. SUBSTITUTED PYRAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
CA3002846A1 (en) 2015-10-27 2017-05-04 Merck Sharp & Dohme Corp. Substituted bicyclic pyrazole compounds as rorgammat inhibitors and uses thereof
MX2018005004A (es) 2015-10-27 2018-09-12 Merck Sharp & Dohme Compuestos de indazol substituidos como inhibidores de rorgammat y sus usos.
WO2017075185A1 (en) 2015-10-27 2017-05-04 Merck Sharp & Dohme Corp. Heteroaryl substituted benzoic acids as rorgammat inhibitors and uses thereof
US20190174760A1 (en) * 2016-07-01 2019-06-13 Nihon Nohyaku Co., Ltd. N-alkylsulfonyl condensed heterocyclic compound or salt thereof, insecticide comprising the compound, and method for using the insecticide
JP6853271B2 (ja) 2016-12-27 2021-03-31 日本農薬株式会社 ４ｈ‐ピロロピリジン化合物、又はその塩類、及びそれらの化合物を含有する農園芸用殺虫剤並びにその使用方法
EP3689872B1 (en) * 2017-09-26 2022-11-02 Sumitomo Chemical Company, Limited Heterocyclic compound and harmful arthropod controlling agent containing same
KR20200098492A (ko) 2017-10-18 2020-08-20 레닥 크롭 프로텍션 리미티드 농약으로서 벤즈이미다졸 화합물
FI3728252T3 (fi) 2017-12-18 2023-10-18 Bristol Myers Squibb Co 4-atsaindoliyhdisteitä
CN110156775A (zh) * 2018-02-12 2019-08-23 新发药业有限公司 一种吡昔替尼的简便制备方法
FI3796975T3 (fi) 2018-05-22 2023-11-20 Orsobio Inc Sulfonyyliaminobentsamidijohdannaisia
TWI748194B (zh) * 2018-06-28 2021-12-01 德商菲尼克斯 Ｆｘｒ有限責任公司 含有雙環核心部分之新穎lxr調節劑
US20220227763A1 (en) * 2019-05-29 2022-07-21 Syngenta Crop Protection Ag Microbiocidal derivatives
EP4188928B1 (en) 2020-07-29 2024-07-24 Bayer Aktiengesellschaft Substituted 1 h-pyrrolo[3,2-b]pyridin compounds and methods of use thereof
US20230391769A1 (en) 2020-07-29 2023-12-07 Bayer Aktiengesellschaft Substituted heterocyclic compounds and therapeutic uses thereof
CN112661694B (zh) * 2020-12-11 2023-04-11 西安凯立新材料股份有限公司 一种4-(二甲氧基甲基)-哌啶的制备方法
EP4469457A1 (en) * 2022-01-27 2024-12-04 The Broad Institute Inc. Substituted heterocyclic csnk1 inhibitors
CN115124527B (zh) * 2022-05-31 2024-03-12 武汉智汇农耀科技有限公司 一种杂环酰胺-氮杂吲哚类化合物及其制备方法和应用、一种除草剂
CN118440080B (zh) * 2024-05-08 2024-12-20 广东省科学院微生物研究所(广东省微生物分析检测中心) 三苯胺类阳离子化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE267200T1 (de) * 1997-10-20 2004-06-15 Hoffmann La Roche Bicyclische kinase inhibitoren
WO2004014922A1 (en) * 2002-08-10 2004-02-19 Astex Technology Limited 3-(carbonyl) 1h-indazole compounds as cyclin dependent kinases (cdk) inhibitors
WO2007085660A1 (en) 2006-01-30 2007-08-02 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Pesticidal composition comprising indole derivates

Also Published As

Publication number Publication date
BRPI0810679A2 (pt) 2014-10-07
US20100184598A1 (en) 2010-07-22
RU2009143567A (ru) 2011-06-10
WO2008132434A3 (en) 2009-10-15
JP2010525039A (ja) 2010-07-22
CN101784191A (zh) 2010-07-21
TW200847926A (en) 2008-12-16
MX2009011337A (es) 2009-11-05
CO6140003A2 (es) 2010-03-19
EP2136640A2 (en) 2009-12-30
ZA200906887B (en) 2012-03-28
CL2008001214A1 (es) 2008-11-03
ECSP099699A (es) 2009-11-30
KR20100015918A (ko) 2010-02-12
AU2008244055A1 (en) 2008-11-06
CR11076A (es) 2009-12-30
GB0708141D0 (en) 2007-06-06
IL201195A0 (en) 2010-05-17
WO2008132434A2 (en) 2008-11-06
CA2682773A1 (en) 2008-11-06
US8084395B2 (en) 2011-12-27

Similar Documents

Publication Publication Date Title
AR066310A1 (es) Derivados de 4-aza indol y su uso como fungicidas
HRP20220140T1 (hr) Herbicidni spojevi
AR076517A1 (es) Metodo para controlar la vegetacion no deseada
PE20080998A1 (es) Derivados de pirazol como inhibidores del sistema enzimatico cyp450
AR103102A2 (es) Combinaciones sinérgicas de productos activos fungicidas
ZA200404022B (en) Quinazoline(di) ones for invertebrate pest control
NO20083822L (no) Farmasoytisk antikreftpreparat
AR074909A1 (es) Compuestos de imina para combatir plagas de invertebrados
PE20091694A1 (es) DERIVADOS POLISUSTITUIDOS DE 6-HETEROARIL-IMIDAZO[1,2-a] PIRIDINAS COMO MODULADORES DE LOS RECEPTORES NOT Y SU PREPARACION
PE20080772A1 (es) Nuevos derivados de bipiridina sustituidos y su uso
JP2018521958A5 (es)
TW200604180A (en) Anthranilamide insecticides
PE20070243A1 (es) Compuestos heterociclicos como inhibidores de la transcriptasa reversa de vih
PE20141827A1 (es) Inhibidores de proteinas quinasas
MY161631A (en) Herbicidal pyrimidone derivatives
TN2009000011A1 (en) Pyrido [2,3-b] pyrazine derivatives useful as herbicidal compounds
NZ599040A (en) 2,4-disubstituted pyrido[4,3-d]pyrimidin-5(6h)-one compounds for selective inhibitors of lrrk2 and syk kinases
AR111365A1 (es) Oxadiazoles sustituidos para combatir hongos fitopatógenos
AR106735A1 (es) Composiciones y métodos insecticidas
MA32350B1 (fr) Composition et methode de lutte contre les organismes nuisibles
PE20080948A1 (es) Derivados de imidazol como moduladores de la senda de hedgehog
AR082868A1 (es) Composiciones fungicidas en base a derivados de pirazol
DE602006018152D1 (de) Triazolderivate als modulatoren von dopamin-d3-rezeptoren
AR066478A1 (es) Derivados heterociclicos sustituidos y su uso farmaceutico y composiciones
PE20080211A1 (es) Compuestos derivados de 6-(bencilo sustituido con heterociclilo)-4-oxoquinolina como inhibidores de integrasa del vih

Legal Events

Date Code Title Description
FB Suspension of granting procedure