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AR038429A2 - Compuestos 15-alquil-16-hidroxilo de marcfortina - Google Patents

Compuestos 15-alquil-16-hidroxilo de marcfortina

Info

Publication number
AR038429A2
AR038429A2 ARP030100483A ARP030100483A AR038429A2 AR 038429 A2 AR038429 A2 AR 038429A2 AR P030100483 A ARP030100483 A AR P030100483A AR P030100483 A ARP030100483 A AR P030100483A AR 038429 A2 AR038429 A2 AR 038429A2
Authority
AR
Argentina
Prior art keywords
marcfortina
rent
hydroxyl compounds
hydroxyl
compounds
Prior art date
Application number
ARP030100483A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR038429(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AR038429A2 publication Critical patent/AR038429A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Epoxy Compounds (AREA)
  • Percussion Or Vibration Massage (AREA)

Abstract

Reivindicación 1: Compuestos de 15-alquil-16-hidroxilo de la fórmula (1) en donde n1 es 0 a 3, sus N-óxidos y sus sales farmacéuticamente aceptables.
ARP030100483A 1995-07-21 2003-02-13 Compuestos 15-alquil-16-hidroxilo de marcfortina AR038429A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21

Publications (1)

Publication Number Publication Date
AR038429A2 true AR038429A2 (es) 2005-01-12

Family

ID=21695455

Family Applications (10)

Application Number Title Priority Date Filing Date
ARP960103674A AR003466A1 (es) 1995-07-21 1996-07-19 Compuestos 14-hidroxi-2-desoxoparahercuamida b
ARP030100486A AR038432A2 (es) 1995-07-21 2003-02-13 Derivados 1,2-dihidro de parahercuamida y marcfortina
ARP030100483A AR038429A2 (es) 1995-07-21 2003-02-13 Compuestos 15-alquil-16-hidroxilo de marcfortina
ARP030100482A AR038428A2 (es) 1995-07-21 2003-02-13 Compuestos fluorados de marcfortina
ARP030100487A AR038433A2 (es) 1995-07-21 2003-02-13 Derivados 2-alquil-2-desoxo de parahercuamida y marcfortina
ARP030100485A AR038431A2 (es) 1995-07-21 2003-02-13 Derivados 2-desoxo-15-alquilo de marcfortina
ARP030100488A AR038434A2 (es) 1995-07-21 2003-02-13 Compuesto 14,15-dihidro-16-oxoparahercuamida y compuestos 2-desoxo de parahercuamida y marcfortina
ARP030100481A AR038427A2 (es) 1995-07-21 2003-02-13 Compuestos 15-alquil-14-hidroxilo de marcfortina y parahercuamida
ARP030100484A AR038430A2 (es) 1995-07-21 2003-02-13 Derivados de parahercuamida b
ARP060100487A AR052907A1 (es) 1995-07-21 2006-02-10 Compuesto 14,15-deshidro-16-oxoparahercuamida y compuestos 2- desoxo de parahercuamida y marcfortina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ARP960103674A AR003466A1 (es) 1995-07-21 1996-07-19 Compuestos 14-hidroxi-2-desoxoparahercuamida b
ARP030100486A AR038432A2 (es) 1995-07-21 2003-02-13 Derivados 1,2-dihidro de parahercuamida y marcfortina

Family Applications After (7)

Application Number Title Priority Date Filing Date
ARP030100482A AR038428A2 (es) 1995-07-21 2003-02-13 Compuestos fluorados de marcfortina
ARP030100487A AR038433A2 (es) 1995-07-21 2003-02-13 Derivados 2-alquil-2-desoxo de parahercuamida y marcfortina
ARP030100485A AR038431A2 (es) 1995-07-21 2003-02-13 Derivados 2-desoxo-15-alquilo de marcfortina
ARP030100488A AR038434A2 (es) 1995-07-21 2003-02-13 Compuesto 14,15-dihidro-16-oxoparahercuamida y compuestos 2-desoxo de parahercuamida y marcfortina
ARP030100481A AR038427A2 (es) 1995-07-21 2003-02-13 Compuestos 15-alquil-14-hidroxilo de marcfortina y parahercuamida
ARP030100484A AR038430A2 (es) 1995-07-21 2003-02-13 Derivados de parahercuamida b
ARP060100487A AR052907A1 (es) 1995-07-21 2006-02-10 Compuesto 14,15-deshidro-16-oxoparahercuamida y compuestos 2- desoxo de parahercuamida y marcfortina

Country Status (31)

Country Link
US (2) US5703078A (es)
EP (3) EP1489082B1 (es)
JP (2) JP4122447B2 (es)
KR (1) KR100428335B1 (es)
CN (2) CN1125824C (es)
AR (10) AR003466A1 (es)
AT (1) ATE311390T1 (es)
AU (1) AU699644B2 (es)
BR (7) BR9612963B8 (es)
CA (1) CA2225813C (es)
CO (1) CO4750664A1 (es)
CZ (1) CZ296008B6 (es)
DE (1) DE69635524T2 (es)
DK (2) DK1489082T3 (es)
ES (2) ES2249783T3 (es)
FI (2) FI115912B (es)
HK (2) HK1017883A1 (es)
HU (1) HU226296B1 (es)
ID (1) ID30373A (es)
MX (1) MX9800625A (es)
MY (1) MY113806A (es)
NO (1) NO324287B1 (es)
NZ (1) NZ311952A (es)
PL (1) PL185007B1 (es)
PT (1) PT1489082E (es)
RU (1) RU2162090C2 (es)
SI (1) SI0871631T1 (es)
SK (2) SK285248B6 (es)
TW (1) TW334436B (es)
WO (1) WO1997003988A1 (es)
ZA (1) ZA965908B (es)

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ZA976761B (en) * 1996-09-09 1999-01-29 Upjohn Co 25 Methylene and 24,25-epoxy marcfortines and paraherquamides
AU4911097A (en) * 1996-11-15 1998-06-03 Pharmacia & Upjohn Company 1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents
PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
ES2551130T3 (es) 2008-11-14 2015-11-16 Merial, Inc. Compuestos de arilazol-2-ilcianoetilamino parasiticidas enriquecidos enantioméricamente
CN102271672B (zh) 2008-11-19 2015-02-04 梅里亚有限公司 用于治疗寄生物感染的包含单独的或与甲脒组合的1-芳基吡唑的组合物
CA2745434C (en) 2008-12-04 2017-06-20 Merial Limited Dimeric avermectin and milbemycin derivatives
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
EP2507209B1 (en) 2009-12-04 2015-07-08 Merial, Inc. Pesticidal bis-organosulfur compounds
PT2513104E (pt) 2009-12-17 2016-06-03 Merial Inc Compostos de di-hidroazole antiparasitários e composições que compreendem os mesmos
EP2512467A1 (en) 2009-12-17 2012-10-24 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
EP2640728B1 (en) 2010-11-16 2016-09-07 Merial, Inc. Novel monensin derivatives for the treatment and prevention of protozoal infections
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
AU2012275435B2 (en) 2011-06-27 2016-07-21 Boehringer Ingelheim Animal Health USA Inc. Amido-pyridyl ether compounds and compositions and their use against parasites
CA2848317C (en) 2011-09-12 2021-01-19 Merial Limited Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof.
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
EP2780008B1 (en) 2011-11-17 2017-07-05 Merial, Inc. Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof
AU2012345813B2 (en) 2011-12-02 2017-02-02 Boehringer lngelheim Vetmedica GMBH Long-acting injectable moxidectin formulations and novel moxidectin crystal forms
NZ746271A (en) 2012-02-06 2020-05-29 Boehringer Ingelheim Animal Health Usa Inc Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
SG11201406730RA (en) 2012-04-20 2014-11-27 Merial Ltd Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
CA2891926A1 (en) 2012-11-20 2014-05-30 Merial, Inc. Anthelmintic compounds and compositions and method of using thereof
EP3063144B1 (en) 2013-11-01 2021-09-08 Boehringer Ingelheim Animal Health USA Inc. Antiparasitic and pesticidal isoxazoline compounds
AU2015247463B2 (en) 2014-04-17 2018-03-29 Basf, Se Use of malononitrile compounds for protecting animals from parasites
US10045979B2 (en) 2014-05-19 2018-08-14 Merial Inc. Anthelmintic compounds
ES2895826T3 (es) 2014-06-19 2022-02-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden derivados de indol, procedimientos y usos de las mismas
US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
JP7045191B2 (ja) 2015-05-20 2022-03-31 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性デプシペプチド化合物
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
JP2019535655A (ja) 2016-10-14 2019-12-12 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 殺虫性及び殺寄生虫性ビニルイソオキサゾリン化合物
BR112019009977A2 (pt) 2016-11-16 2019-08-27 Boehringer Ingelheim Animal Health Usa Inc compostos depsipeptídicos anti-helmínticos
EP3668866B1 (en) 2017-08-14 2023-01-18 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal pyrazole-isoxazoline compounds
WO2019157241A1 (en) 2018-02-08 2019-08-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
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CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
CN113507922A (zh) 2019-03-01 2021-10-15 勃林格殷格翰动物保健美国公司 可注射的氯舒隆组合物、其方法和用途
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Also Published As

Publication number Publication date
EP0871631B1 (en) 2005-11-30
AR038432A2 (es) 2005-01-12
AR038431A2 (es) 2005-01-12
HK1017883A1 (en) 1999-12-03
CA2225813C (en) 2008-02-26
AR038428A2 (es) 2005-01-12
MY113806A (en) 2002-05-31
CO4750664A1 (es) 1999-03-31
AU6337396A (en) 1997-02-18
CN1125824C (zh) 2003-10-29
BR9612972B8 (pt) 2014-10-29
AR038427A2 (es) 2005-01-12
TW334436B (en) 1998-06-21
FI20050238A (fi) 2005-03-04
AU699644B2 (en) 1998-12-10
CN1495183A (zh) 2004-05-12
RU2162090C2 (ru) 2001-01-20
DE69635524T2 (de) 2006-07-06
PT1489082E (pt) 2013-12-23
JP4122447B2 (ja) 2008-07-23
CZ11098A3 (cs) 1998-06-17
WO1997003988A1 (en) 1997-02-06
HK1061242A1 (en) 2004-09-10
CZ296008B6 (cs) 2005-12-14
JPH11509550A (ja) 1999-08-24
NO324287B1 (no) 2007-09-17
NO980255D0 (no) 1998-01-20
BR9612975B8 (pt) 2014-10-29
BR9612974B8 (pt) 2014-10-29
AR052907A1 (es) 2007-04-11
EP1489082B1 (en) 2013-11-20
EP1400523A3 (en) 2004-04-07
DK0871631T3 (da) 2006-03-13
HUP9802221A3 (en) 2000-05-29
EP1489082A1 (en) 2004-12-22
ATE311390T1 (de) 2005-12-15
US5750695A (en) 1998-05-12
BR9609812B8 (pt) 2014-10-29
CA2225813A1 (en) 1997-02-06
HU226296B1 (hu) 2008-08-28
MX9800625A (es) 1998-04-30
PL185007B1 (pl) 2003-01-31
HUP9802221A2 (hu) 1999-02-01
FI118471B (fi) 2007-11-30
BR9609812A (pt) 1999-03-02
ES2439569T3 (es) 2014-01-23
BR9612944B8 (pt) 2014-10-29
AR038433A2 (es) 2005-01-12
CN1277830C (zh) 2006-10-04
FI980112A0 (fi) 1998-01-20
DE69635524D1 (de) 2006-01-05
BR9612973B8 (pt) 2014-10-29
AR038434A2 (es) 2005-01-12
ZA965908B (en) 1997-01-12
KR100428335B1 (ko) 2004-06-16
SK284833B6 (sk) 2005-12-01
SK5498A3 (en) 1998-08-05
PL324574A1 (en) 1998-06-08
DK1489082T3 (da) 2013-12-09
NO980255L (no) 1998-03-20
ES2249783T3 (es) 2006-04-01
EP0871631A1 (en) 1998-10-21
EP1400523A2 (en) 2004-03-24
BR9612963B8 (pt) 2014-10-29
FI980112A (fi) 1998-01-20
ID30373A (id) 1997-01-23
AR038430A2 (es) 2005-01-12
FI115912B (fi) 2005-08-15
NZ311952A (en) 1999-03-29
JP2008007516A (ja) 2008-01-17
AR003466A1 (es) 1998-08-05
US5703078A (en) 1997-12-30
CN1191537A (zh) 1998-08-26
SK285248B6 (sk) 2006-09-07
SI0871631T1 (sl) 2006-04-30

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