AR029317A1 - UN PROCEDIMIENTO PARA PREPARAR UNA COMPOSICIoN FARMACÉUTICA QUE COMPRENDE UN SENSIBILIZADOR DE INSULINA. - Google Patents
UN PROCEDIMIENTO PARA PREPARAR UNA COMPOSICIoN FARMACÉUTICA QUE COMPRENDE UN SENSIBILIZADOR DE INSULINA.Info
- Publication number
- AR029317A1 AR029317A1 ARP990105701A ARP990105701A AR029317A1 AR 029317 A1 AR029317 A1 AR 029317A1 AR P990105701 A ARP990105701 A AR P990105701A AR P990105701 A ARP990105701 A AR P990105701A AR 029317 A1 AR029317 A1 AR 029317A1
- Authority
- AR
- Argentina
- Prior art keywords
- insulin sensitizer
- pharmaceutical composition
- prepare
- procedure
- insulin
- Prior art date
Links
- 229940122355 Insulin sensitizer Drugs 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000036470 plasma concentration Effects 0.000 abstract 3
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003981 vehicle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Abstract
Un procedimiento para preparar una composicion farmacéutica, que comprende un sensibilizador de insulina y un vehículo farmacéuticamente aceptable para el mismo, adaptándose la composicion para proporcionar una concentracion plasmática del sensibilizador de insulina al menos igual a insulina que comprende formular el sensibilizador de insulina y el vehículo farmacéuticamente aceptable con objeto de proporcionar una concentracion plasmática del sensibilizador de insulina al menos igual a una concentracion plasmática umbral del sensibilizador de insulina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9824893.3A GB9824893D0 (en) | 1998-11-12 | 1998-11-12 | Novel method of treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
AR029317A1 true AR029317A1 (es) | 2003-06-25 |
Family
ID=10842389
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990105701A AR029317A1 (es) | 1998-11-12 | 1999-11-10 | UN PROCEDIMIENTO PARA PREPARAR UNA COMPOSICIoN FARMACÉUTICA QUE COMPRENDE UN SENSIBILIZADOR DE INSULINA. |
ARP990105700A AR029149A1 (es) | 1998-11-12 | 1999-11-10 | USO DE UN SENSIBILIZADOR DE INSULINA, UNA COMPOSICIoN FARMACÉUTICA Y UN MÉTODO PARA DETERMINAR LA CONCENTRACIoN PLASMA TICA UMBRAL PARA UN COMPUESTO ANTIDIABÉTICO. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990105700A AR029149A1 (es) | 1998-11-12 | 1999-11-10 | USO DE UN SENSIBILIZADOR DE INSULINA, UNA COMPOSICIoN FARMACÉUTICA Y UN MÉTODO PARA DETERMINAR LA CONCENTRACIoN PLASMA TICA UMBRAL PARA UN COMPUESTO ANTIDIABÉTICO. |
Country Status (40)
Country | Link |
---|---|
EP (2) | EP1135128B1 (es) |
JP (1) | JP2003521455A (es) |
KR (2) | KR20010080440A (es) |
CN (3) | CN1771943A (es) |
AP (2) | AP2005003432A0 (es) |
AR (2) | AR029317A1 (es) |
AT (1) | ATE366573T1 (es) |
AU (1) | AU768303B2 (es) |
BG (2) | BG110061A (es) |
BR (1) | BR9915284A (es) |
CA (1) | CA2350425C (es) |
CO (1) | CO5150158A1 (es) |
CY (1) | CY1106892T1 (es) |
CZ (1) | CZ299801B6 (es) |
DE (1) | DE69936533T2 (es) |
DK (1) | DK1135128T3 (es) |
DZ (1) | DZ2938A1 (es) |
EA (2) | EA200700968A1 (es) |
ES (1) | ES2289833T3 (es) |
GB (1) | GB9824893D0 (es) |
HK (1) | HK1041202B (es) |
HR (1) | HRP20010344B1 (es) |
HU (1) | HUP0104262A3 (es) |
IL (1) | IL143088A0 (es) |
MA (1) | MA26759A1 (es) |
MY (1) | MY128347A (es) |
NO (1) | NO328391B1 (es) |
NZ (1) | NZ527132A (es) |
OA (1) | OA12193A (es) |
PE (1) | PE20001239A1 (es) |
PL (1) | PL349421A1 (es) |
PT (1) | PT1135128E (es) |
RS (1) | RS50130B (es) |
SK (1) | SK286357B6 (es) |
TR (1) | TR200101348T2 (es) |
TW (1) | TWI234456B (es) |
UA (1) | UA79730C2 (es) |
UY (2) | UY25797A1 (es) |
WO (1) | WO2000027341A2 (es) |
ZA (1) | ZA200103793B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY125516A (en) | 1999-11-16 | 2006-08-30 | Smithkline Beecham Plc | Novel composition based on thiazolidinedione and metformin and use |
ES2259736T3 (es) * | 2001-12-21 | 2006-10-16 | Smithkline Beecham Corporation | Regimen de dosificacion para activadores de ppar-gamma-. |
WO2012074375A1 (en) * | 2010-12-01 | 2012-06-07 | N.V. Nutricia | Prevention or treatment of overweight and obesity in type 2 diabetic patients |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
JPS5697277A (en) * | 1980-01-07 | 1981-08-05 | Takeda Chem Ind Ltd | Thiazolidine derivative |
JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
US4582839A (en) * | 1984-03-21 | 1986-04-15 | Takeda Chemical Industries, Ltd. | 2,4-thiazolidinediones |
CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物,其制备方法和用途 |
JPH06779B2 (ja) * | 1985-06-10 | 1994-01-05 | 武田薬品工業株式会社 | チアゾリジオン誘導体およびそれを含んでなる医薬組成物 |
US4812570A (en) * | 1986-07-24 | 1989-03-14 | Takeda Chemical Industries, Ltd. | Method for producing thiazolidinedione derivatives |
ES2137915T3 (es) * | 1987-09-04 | 2000-01-01 | Beecham Group Plc | Derivados de tiazolidindiona sustituida. |
US4791125A (en) * | 1987-12-02 | 1988-12-13 | Pfizer Inc. | Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents |
WO1989008651A1 (en) * | 1988-03-08 | 1989-09-21 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
US5061717A (en) * | 1988-03-08 | 1991-10-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
GB8919417D0 (en) * | 1989-08-25 | 1989-10-11 | Beecham Group Plc | Novel compounds |
WO1991007107A1 (en) * | 1989-11-13 | 1991-05-30 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
JPH0469331A (ja) * | 1990-07-10 | 1992-03-04 | Asahi Chem Ind Co Ltd | 徐放性エマルジョン製剤 |
JP2572673B2 (ja) * | 1990-07-25 | 1997-01-16 | エスエス製薬株式会社 | 徐放性錠剤 |
JPH04210683A (ja) * | 1990-12-06 | 1992-07-31 | Terumo Corp | チアゾリジン−2,4−ジオン誘導体およびこれを含有する糖尿病合併症治療薬 |
US5183823A (en) * | 1991-04-11 | 1993-02-02 | Takeda Chemical Industries, Ltd. | Pyridine n-oxide compounds which are useful as hypoglycemic and hypolipidemic agents |
FR2680512B1 (fr) * | 1991-08-20 | 1995-01-20 | Adir | Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
EP0601001B1 (en) * | 1991-08-26 | 1997-04-16 | PHARMACIA & UPJOHN COMPANY | Liquid food product containing 3-guanidinopropionic acid |
GB9218830D0 (en) * | 1992-09-05 | 1992-10-21 | Smithkline Beecham Plc | Novel compounds |
US5478853A (en) * | 1992-10-12 | 1995-12-26 | Adir Et Compagnie | Thazolidinedione compounds |
US5506245A (en) * | 1992-10-12 | 1996-04-09 | Adir Et Compagnie | Thiazolidinedione compounds |
CA2115587A1 (en) * | 1993-02-18 | 1994-08-19 | Hayato Kihara | Styrene copolymers, polystyrene compositions, processes for producing styrene copolymers, and injection-molded articles |
DE4317320A1 (de) * | 1993-05-25 | 1994-12-01 | Boehringer Mannheim Gmbh | Neue Thiazolidindione und diese enthaltende Arzneimittel |
JP3081245B2 (ja) * | 1993-09-15 | 2000-08-28 | 三共株式会社 | Niddmの発症を阻止又は遅延するためのチアゾリジンジオン類の用途 |
US5478852C1 (en) * | 1993-09-15 | 2001-03-13 | Sankyo Co | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus |
US5902726A (en) * | 1994-12-23 | 1999-05-11 | Glaxo Wellcome Inc. | Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma |
US5708012A (en) * | 1995-04-28 | 1998-01-13 | Sankyo Company, Limited | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus |
US6011049A (en) * | 1997-02-19 | 2000-01-04 | Warner-Lambert Company | Combinations for diabetes |
US5859037A (en) * | 1997-02-19 | 1999-01-12 | Warner-Lambert Company | Sulfonylurea-glitazone combinations for diabetes |
-
1998
- 1998-11-12 GB GBGB9824893.3A patent/GB9824893D0/en not_active Ceased
-
1999
- 1999-11-10 DZ DZ990238A patent/DZ2938A1/xx active
- 1999-11-10 AR ARP990105701A patent/AR029317A1/es unknown
- 1999-11-10 AR ARP990105700A patent/AR029149A1/es unknown
- 1999-11-11 MY MYPI99004899A patent/MY128347A/en unknown
- 1999-11-12 AT AT99960293T patent/ATE366573T1/de active
- 1999-11-12 PL PL99349421A patent/PL349421A1/xx not_active Application Discontinuation
- 1999-11-12 PE PE1999001148A patent/PE20001239A1/es not_active Application Discontinuation
- 1999-11-12 SK SK642-2001A patent/SK286357B6/sk not_active IP Right Cessation
- 1999-11-12 JP JP2000580572A patent/JP2003521455A/ja active Pending
- 1999-11-12 BR BR9915284-3A patent/BR9915284A/pt not_active Application Discontinuation
- 1999-11-12 KR KR1020017006028A patent/KR20010080440A/ko not_active Application Discontinuation
- 1999-11-12 PT PT99960293T patent/PT1135128E/pt unknown
- 1999-11-12 OA OA00100118A patent/OA12193A/en unknown
- 1999-11-12 RS YUP-374/01A patent/RS50130B/sr unknown
- 1999-11-12 AP AP2005003432A patent/AP2005003432A0/xx unknown
- 1999-11-12 WO PCT/US1999/026746 patent/WO2000027341A2/en active IP Right Grant
- 1999-11-12 CZ CZ20011656A patent/CZ299801B6/cs not_active IP Right Cessation
- 1999-11-12 EA EA200700968A patent/EA200700968A1/ru unknown
- 1999-11-12 ES ES99960293T patent/ES2289833T3/es not_active Expired - Lifetime
- 1999-11-12 IL IL14308899A patent/IL143088A0/xx unknown
- 1999-11-12 EP EP99960293A patent/EP1135128B1/en not_active Expired - Lifetime
- 1999-11-12 DE DE69936533T patent/DE69936533T2/de not_active Expired - Lifetime
- 1999-11-12 CA CA002350425A patent/CA2350425C/en not_active Expired - Fee Related
- 1999-11-12 CO CO99071567A patent/CO5150158A1/es unknown
- 1999-11-12 CN CNA2005101201583A patent/CN1771943A/zh active Pending
- 1999-11-12 HU HU0104262A patent/HUP0104262A3/hu unknown
- 1999-11-12 CN CNA2008100058350A patent/CN101244062A/zh active Pending
- 1999-11-12 TR TR2001/01348T patent/TR200101348T2/xx unknown
- 1999-11-12 AU AU17196/00A patent/AU768303B2/en not_active Ceased
- 1999-11-12 UA UA2001053164A patent/UA79730C2/uk unknown
- 1999-11-12 UY UY25797A patent/UY25797A1/es not_active Application Discontinuation
- 1999-11-12 KR KR1020077009372A patent/KR20070048279A/ko not_active Application Discontinuation
- 1999-11-12 EA EA200100539A patent/EA009192B1/ru not_active IP Right Cessation
- 1999-11-12 AP APAP/P/2001/002137A patent/AP1580A/en active
- 1999-11-12 NZ NZ527132A patent/NZ527132A/en not_active IP Right Cessation
- 1999-11-12 CN CNB998154806A patent/CN1235586C/zh not_active Expired - Fee Related
- 1999-11-12 EP EP06124048A patent/EP1759698A1/en not_active Withdrawn
- 1999-11-12 DK DK99960293T patent/DK1135128T3/da active
- 1999-11-15 UY UY25801A patent/UY25801A1/es not_active Application Discontinuation
- 1999-12-24 TW TW088122851A patent/TWI234456B/zh not_active IP Right Cessation
-
2001
- 2001-05-10 NO NO20012301A patent/NO328391B1/no not_active IP Right Cessation
- 2001-05-10 ZA ZA200103793A patent/ZA200103793B/en unknown
- 2001-05-11 HR HR20010344A patent/HRP20010344B1/xx not_active IP Right Cessation
- 2001-05-11 MA MA26193A patent/MA26759A1/fr unknown
- 2001-06-07 BG BG110061A patent/BG110061A/bg unknown
- 2001-06-07 BG BG105569A patent/BG65577B1/bg unknown
-
2002
- 2002-02-11 HK HK02101081.6A patent/HK1041202B/zh not_active IP Right Cessation
-
2007
- 2007-09-27 CY CY20071101240T patent/CY1106892T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |