[go: up one dir, main page]

AR020032A1 - Derivados de 1,3 -metil eritromicina. - Google Patents

Derivados de 1,3 -metil eritromicina.

Info

Publication number
AR020032A1
AR020032A1 ARP000102485A ARP000102485A AR020032A1 AR 020032 A1 AR020032 A1 AR 020032A1 AR P000102485 A ARP000102485 A AR P000102485A AR P000102485 A ARP000102485 A AR P000102485A AR 020032 A1 AR020032 A1 AR 020032A1
Authority
AR
Argentina
Prior art keywords
compounds
derivatives
formula
methyl erythromycin
erythromycin
Prior art date
Application number
ARP000102485A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR020032A1 publication Critical patent/AR020032A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se refiere a compuestos de formula 1 y a sales, promedicamentos y solvatos de éstos farmacéuticamente aceptables, en los que R1, R2, R3, R4, R5, Rf, A, Xe Y son como se definieron en la descripcion. La invencion también se refiere a composiciones faramcéuticas que contienen los compuestos de formulas 1, aprocedimienTos de utilizacion de los compuestos de formula 1 en el tratamiento de infecciones y a procedimientos de preparacion de los compuestos de formula 1.
ARP000102485A 1999-05-24 2000-05-22 Derivados de 1,3 -metil eritromicina. AR020032A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13546899P 1999-05-24 1999-05-24

Publications (1)

Publication Number Publication Date
AR020032A1 true AR020032A1 (es) 2002-03-27

Family

ID=22468240

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102485A AR020032A1 (es) 1999-05-24 2000-05-22 Derivados de 1,3 -metil eritromicina.

Country Status (32)

Country Link
US (2) US20030100518A1 (es)
EP (1) EP1180110A1 (es)
JP (1) JP2003500414A (es)
KR (1) KR20020016799A (es)
CN (1) CN1351608A (es)
AP (1) AP2001002302A0 (es)
AR (1) AR020032A1 (es)
AU (1) AU3832100A (es)
BG (1) BG106127A (es)
BR (1) BR0010938A (es)
CA (1) CA2373117C (es)
CZ (1) CZ20013733A3 (es)
DZ (1) DZ3045A1 (es)
EA (1) EA200100983A1 (es)
EE (1) EE200100613A (es)
HK (1) HK1045523A1 (es)
HR (1) HRP20010866A2 (es)
HU (1) HUP0201516A3 (es)
IL (1) IL145739A0 (es)
IS (1) IS6128A (es)
MA (1) MA26740A1 (es)
NO (1) NO20015172L (es)
OA (1) OA11945A (es)
PA (1) PA8495101A1 (es)
PE (1) PE20010171A1 (es)
PL (1) PL352720A1 (es)
SK (1) SK15162001A3 (es)
TN (1) TNSN00108A1 (es)
TR (1) TR200103395T2 (es)
UY (1) UY26161A1 (es)
WO (1) WO2000071557A1 (es)
ZA (1) ZA200109595B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
ID28286A (id) * 1998-11-03 2001-05-10 Pfizer Prod Inc Antibiotik-antibiotik makrolida baru
IL144178A0 (en) 1999-01-27 2002-05-23 Pfizer Prod Inc Ketolide antibiotics
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
ES2272273T3 (es) 1999-04-16 2007-05-01 Kosan Biosciences, Inc. Agentes antiinfecciosos macrolidos.
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
CA2370743A1 (en) 1999-04-16 2000-10-26 Dennis Hlasta Ketolide antibacterials
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
CZ20013733A3 (cs) 1999-05-24 2002-11-13 Pfizer Products Inc. Deriváty 13-methylerythromycinu
PT1167376E (pt) 2000-06-30 2004-09-30 Pfizer Prod Inc Antibioticos macrolidos
GB0127349D0 (en) 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
US6825170B2 (en) 2001-12-05 2004-11-30 Ortho-Mcneil Pharmaceutical, Inc. 6-O-acyl ketolide antibacterials
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
MXPA04010556A (es) * 2002-04-25 2005-02-17 Abbott Lab Antibacterianos oxalida.
GB0225384D0 (en) 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
US7414030B2 (en) * 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
UA85937C2 (uk) 2004-12-21 2009-03-10 Пфайзер Продактс Інк. Макроліди
DE602007006663D1 (de) 2006-06-12 2010-07-01 Univ Ramot Verfahren zur behandlung von krebs
CN101175322B (zh) * 2007-11-16 2010-12-15 华为技术有限公司 一种小区选择的方法
KR101043637B1 (ko) * 2009-07-13 2011-06-24 태석정공 주식회사 휴대용 듀얼 모니터의 카메라 모듈 결합구조
AR085286A1 (es) * 2011-02-21 2013-09-18 Taisho Pharmaceutical Co Ltd Derivado de macrolido sustituido en la posicion c-4
CA2894992A1 (en) 2012-12-24 2014-07-03 Ramot At Tel-Aviv University Ltd. Agents for treating genetic diseases resulting from nonsense mutations, and methods for identifying the same
BR112015025159A2 (pt) 2013-04-04 2017-07-18 Harvard College macrolídeos e métodos de sua preparação e uso
WO2016057798A1 (en) 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
US10640528B2 (en) 2015-03-25 2020-05-05 President And Fellows Of Havard College Macrolides with modified desosamine sugars and uses thereof

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US13281A (en) * 1855-07-17 Churn
US52328A (en) * 1866-01-30 Improved mode of attaching car-wheels to axles
US61856A (en) * 1867-02-05 Enos s
US40007A (en) * 1863-09-22 Improvement in railroad-car brakes
US61858A (en) * 1867-02-05 Improved washing machine
US50254A (en) * 1865-10-03 Improvement in portable scales
US13662A (en) * 1855-10-09 Improvement in sewing-machines
US77302A (en) * 1868-04-28 mat son
US13665A (en) * 1855-10-09 Daguerreotype-plate holder
US111317A (en) * 1871-01-31 Improvement in culinary vessels
US100518A (en) * 1870-03-08 Roland s
US100742A (en) * 1870-03-15 Improvement in lawn-mowers
US25937A (en) * 1859-11-01 ballou
US156027A (en) * 1874-10-20 Improvement in loom-shuttles
US61857A (en) * 1867-02-05 Improvement in top-drivers or spinners
US3923784A (en) 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
YU43116B (en) 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
JPS61103890A (ja) 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
JPS61229895A (ja) 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−ｎ−メチルエリスロマイシン誘導体
GB8521402D0 (en) 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
US4672056A (en) 1985-11-12 1987-06-09 Abbott Laboratories Erythromycin A derivatives and method of use
HU198913B (en) 1987-09-03 1989-12-28 Pliva Pharm & Chem Works Process for producing 10-dihydro-10-deoxo-11-aza-erythronolide a-derivatives and pharmaceutical compositions containing them as active components
US5141926A (en) * 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
IL114589A (en) 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US6060234A (en) 1991-01-17 2000-05-09 Abbott Laboratories Polyketide derivatives and recombinant methods for making same
US5824513A (en) 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
US5985844A (en) 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
CA2064634C (en) 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
US5523399A (en) 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
FR2691464B1 (fr) 1992-05-21 1995-06-02 Roussel Uclaf Nouveaux dérivés de la 1-oxa 6-azacyclopentadécane 13,15-dione, leur procédé de préparation et leur application comme médicaments.
US5414926A (en) 1992-10-09 1995-05-16 Sumitomo Wiring Systems, Ltd. Terminal crimping apparatus
US5527780A (en) 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5332807A (en) 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
FR2702480B1 (fr) 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP931480B1 (en) 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
FR2718450B1 (fr) 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732023B1 (fr) 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732684B1 (fr) 1995-04-06 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5747466A (en) 1995-11-08 1998-05-05 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins A and B
US6274715B1 (en) 1995-11-08 2001-08-14 Abbott Laboratories Tricyclic erythromycin derivatives
FR2742757B1 (fr) 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745290B1 (fr) 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
US5719272A (en) 1996-04-02 1998-02-17 Abbott Laboratories 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
BR9708929A (pt) * 1996-05-07 1999-08-03 Abbott Lab Composto composição farmacêutica e processos para controlar uma infecção bacteriana em um mamífero e para preparar compostos de macrólidos
JP2000509712A (ja) * 1996-05-07 2000-08-02 アボツト・ラボラトリーズ ６―ｏ―置換エリスロマイシン及びその製造方法
FR2748746B1 (fr) 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
DE19626036A1 (de) 1996-06-28 1998-01-02 Whitaker Corp Optischer Steckverbinder
US6271255B1 (en) 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
GB2331518B (en) 1996-07-05 2001-03-14 Biotica Tech Ltd Erythromycins and process for their preparation
FR2751656B1 (fr) 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
US5804565A (en) 1996-09-24 1998-09-08 Taisho Pharmaceutical Co., Ltd. Erythromycin A derivatives
FR2754821B1 (fr) 1996-10-23 2003-04-04 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
HUP0000198A3 (en) 1996-11-27 2000-09-28 Taisho Pharmaceutical Co Ltd Erythromycin a derivatives
FR2757168B1 (fr) 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
WO1998040392A1 (fr) 1997-03-10 1998-09-17 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
US6162794A (en) 1997-05-09 2000-12-19 Pfizer Inc. Erythromycin derivatives
HN1998000086A (es) 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
US6407074B1 (en) 1997-06-11 2002-06-18 Pfizer Inc C-4″-substituted macrolide derivatives
ID24529A (id) 1997-06-11 2000-07-20 Pfizer Prod Inc Turunan-turunan 9-oksima eritromisin
US20020025937A1 (en) 2000-03-20 2002-02-28 Yong-Jin Wu 9-oxime erythromycin derivatives
EP0895999A1 (en) 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
US5868549A (en) * 1997-08-29 1999-02-09 Hk Systems, Inc. Palletizer with air assisted slide plate assembly and indexing pallet hoist
HN1998000159A (es) 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
PA8461401A1 (es) 1997-10-29 2000-05-24 Pfizer Prod Inc Derivados de eritromicina triciclicos
CN1284961A (zh) 1997-12-11 2001-02-21 北陆制药株式会社 红霉素衍生物
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
DK0941998T3 (da) * 1998-03-03 2004-09-20 Pfizer Prod Inc 3,6-ketalmakrolidantibiotika
FR2777282B1 (fr) 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
US6248719B1 (en) 1998-06-03 2001-06-19 Pfizer Inc Tricyclic 3-keto derivatives of 6-O-methylerthromycin
US6043227A (en) 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
AU5299499A (en) 1998-09-22 2000-04-10 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
US6100240A (en) 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
FR2785612A1 (fr) 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
ID28286A (id) 1998-11-03 2001-05-10 Pfizer Prod Inc Antibiotik-antibiotik makrolida baru
UA70972C2 (uk) 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків
FR2786188B1 (fr) 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
IL144178A0 (en) 1999-01-27 2002-05-23 Pfizer Prod Inc Ketolide antibiotics
FR2789392B1 (fr) 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
CA2370743A1 (en) 1999-04-16 2000-10-26 Dennis Hlasta Ketolide antibacterials
US20020061857A1 (en) 1999-04-23 2002-05-23 Yong-Jin Wu 9-amino-3-oxo erythromycin derivatives
US20020077302A1 (en) 1999-04-23 2002-06-20 Yong-Jin Wu Tricyclic erythromycin derivatives
US6355620B1 (en) 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
CZ20013733A3 (cs) 1999-05-24 2002-11-13 Pfizer Products Inc. Deriváty 13-methylerythromycinu
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
EP1146051A3 (en) 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020061856A1 (en) 2000-04-24 2002-05-23 Yong-Jin Wu Novel tricyclic erythromycin derivatives
PT1167376E (pt) 2000-06-30 2004-09-30 Pfizer Prod Inc Antibioticos macrolidos
US20020115621A1 (en) 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
US20020128213A1 (en) 2000-09-25 2002-09-12 Leonard Katz Sixteen-membered macrolide compounds

Also Published As

Publication number Publication date
IS6128A (is) 2001-10-26
US6777543B2 (en) 2004-08-17
NO20015172D0 (no) 2001-10-23
OA11945A (en) 2006-04-13
JP2003500414A (ja) 2003-01-07
BR0010938A (pt) 2002-03-19
AU3832100A (en) 2000-12-12
EE200100613A (et) 2003-02-17
CN1351608A (zh) 2002-05-29
HUP0201516A2 (en) 2002-08-28
HK1045523A1 (zh) 2002-11-29
HRP20010866A2 (en) 2003-06-30
US20030100518A1 (en) 2003-05-29
ZA200109595B (en) 2003-05-28
US20030229031A1 (en) 2003-12-11
CA2373117A1 (en) 2000-11-30
IL145739A0 (en) 2002-07-25
CZ20013733A3 (cs) 2002-11-13
NO20015172L (no) 2002-01-23
EP1180110A1 (en) 2002-02-20
PE20010171A1 (es) 2001-02-10
MA26740A1 (fr) 2004-12-20
WO2000071557A1 (en) 2000-11-30
CA2373117C (en) 2006-02-28
PL352720A1 (en) 2003-09-08
DZ3045A1 (fr) 2004-03-27
UY26161A1 (es) 2000-12-29
AP2001002302A0 (en) 2001-10-25
PA8495101A1 (es) 2002-08-26
TR200103395T2 (tr) 2002-04-22
HUP0201516A3 (en) 2003-03-28
EA200100983A1 (ru) 2002-10-31
SK15162001A3 (sk) 2003-02-04
BG106127A (bg) 2002-05-31
TNSN00108A1 (fr) 2002-05-30
KR20020016799A (ko) 2002-03-06

Similar Documents

Publication Publication Date Title
AR020032A1 (es) Derivados de 1,3 -metil eritromicina.
PA8494101A1 (es) Derivados heterociclicos utiles como agentes anticancerosos
CO4810375A1 (es) Derivados de 9-amino-3-ceto eritromicina
PA8547701A1 (es) Nucleosidos 4 substituidos.
GT200100137A (es) Pro-drogas de derivados de 4-fenil-piridina.
MXPA02012905A (es) Derivados de colquinol como agentes de dano vascular..
PA8490601A1 (es) Derivados quinolin-2-ona sustituidos con heteroarilo utiles como agentes anticancerigenos.
ATE450533T1 (de) Carboxamidderivate
PA8591701A1 (es) Derivados de pirrolopirimidina
ATE316083T1 (de) Adamantanderivate
PA8472301A1 (es) Derivados de isotiazol utiles como agentes anticancerosos
NO20085078L (no) Nye forbindelser
AR023574A1 (es) Compuestos de azepinindol tetraciclico,composiciones farmaceuticas y el uso de dichos compuestos para preparar un medicamento, e intermediarios
AR023423A1 (es) Derivados de adamantano, procedimientos para su preparacion, composicion farmaceutica, procedimiento para la preparacion de la composicion farmaceutica, yuso de dichos derivados para la manufactura de medicamentos
SE9904505D0 (sv) Novel compounds
PA8451801A1 (es) Derivados de la 9-oxima eritromicina
ES2243579T3 (es) Derivados de pirazolopirideno.
ATE386725T1 (de) Heterocyclylverbindungen
ATE372995T1 (de) Benzo(b)(1,4)dioxepinderivate
PA8568101A1 (es) Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos, y procedimientos para su uso
CL2003002565A1 (es) Compuestos derivados de 3h-quinazolin-4-ona, su proceso de preparacion, composicion farmaceutica que los contiene, y uso en el tratamiento y prevencion de enfermedades mediadas por inhibidores de mao-b, tales como la enfermedad de alzheimer y demenci
PT992509E (pt) Novos derivados macrolidos
UY27980A1 (es) Indoles 2,7-sustituidos
AR007108A1 (es) Agentes antitumorales y antivirales alquilantes, procedimiento para su preparacion, utilizacion de los mismos para la fabricacion de un medicamento y composicion farmaceutica que contiene a dichos agentes.
CO4810376A1 (es) Derivados de eritromicina triciclicos

Legal Events

Date Code Title Description
FA Abandonment or withdrawal