AR000555A1 - Uso de composiciones anabolicas para la masa osea en base a cantidades efectivas no toxicas del ácido Ä3-(n,n-dimetilamino)-1-hidroxipropilidenoÜbisfosfonico o la sal monosodica u otra sal farmacéuticamente aceptable del mismo - Google Patents
Uso de composiciones anabolicas para la masa osea en base a cantidades efectivas no toxicas del ácido Ä3-(n,n-dimetilamino)-1-hidroxipropilidenoÜbisfosfonico o la sal monosodica u otra sal farmacéuticamente aceptable del mismoInfo
- Publication number
- AR000555A1 AR000555A1 AR33481795A AR33481795A AR000555A1 AR 000555 A1 AR000555 A1 AR 000555A1 AR 33481795 A AR33481795 A AR 33481795A AR 33481795 A AR33481795 A AR 33481795A AR 000555 A1 AR000555 A1 AR 000555A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydroxypropylidene
- dimethylamino
- bone mass
- pharmaceutically acceptable
- anabolic
- Prior art date
Links
- 210000000988 bone and bone Anatomy 0.000 title abstract 4
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical class [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 title abstract 2
- 231100000252 nontoxic Toxicity 0.000 title abstract 2
- 230000003000 nontoxic effect Effects 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 230000001195 anabolic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 1
- UGEPSJNLORCRBO-UHFFFAOYSA-N [3-(dimethylamino)-1-hydroxy-1-phosphonopropyl]phosphonic acid Chemical compound CN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O UGEPSJNLORCRBO-UHFFFAOYSA-N 0.000 abstract 1
- 230000003416 augmentation Effects 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000004321 preservation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Uso de una cantidad efectiva y no-tóxica del ácido [3-(N,N-dimetilamino)-1-hidroxipropilideno]-bis-fosfónico o de la sal monosódica u otra salfarmacéuticamente aceptable para la preparación de un medicamento para la preservación y aumentoanabó lico de la masa ósea y para el mejoramiento de laspropiedades biomecánicas del hueso en humanos u otros animales afectados de pérdida de masa ósea.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94120799 | 1994-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR000555A1 true AR000555A1 (es) | 1997-07-10 |
Family
ID=8216571
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR33481795A AR000555A1 (es) | 1994-12-28 | 1995-12-27 | Uso de composiciones anabolicas para la masa osea en base a cantidades efectivas no toxicas del ácido Ä3-(n,n-dimetilamino)-1-hidroxipropilidenoÜbisfosfonico o la sal monosodica u otra sal farmacéuticamente aceptable del mismo |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0800397B1 (es) |
JP (1) | JP3796693B2 (es) |
KR (1) | KR100385697B1 (es) |
AR (1) | AR000555A1 (es) |
AU (1) | AU701258B2 (es) |
BR (1) | BR9510123A (es) |
CA (1) | CA2208714C (es) |
DE (1) | DE69534923T2 (es) |
ES (1) | ES2262145T3 (es) |
WO (1) | WO1996019998A1 (es) |
ZA (1) | ZA9510995B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0753523A1 (en) * | 1995-07-10 | 1997-01-15 | Gador S.A. | Amino-substituted bisphosphonic acids |
DE19719680A1 (de) * | 1997-05-09 | 1998-11-19 | Boehringer Mannheim Gmbh | Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz |
DK0891979T3 (da) * | 1997-07-15 | 2005-01-31 | Gador Sa | Krystallinsk form af N,N-dimethyl-3-amino-1-hydroxypropan-1,1-diphosphonsyre-mononatrium-monohydrat og fremgangsmåde til fremstilling heraf |
AR013994A1 (es) * | 1998-10-30 | 2001-01-31 | Gador Sa | Procedimiento y preparaciones que modulan selectivamente la funcion del osteoblasto para la prevencion y tratamiento de las osteopatias fragilizantes. |
WO2000028982A2 (en) * | 1998-11-19 | 2000-05-25 | The Board Of Trustees For The University Of Arkansas | Increasing bone strength with selected bisphosphonates |
MXPA03006565A (es) | 2001-01-23 | 2005-07-29 | Gador Sa | Composicion comprendiendo bisfosfonatos para la prevencion y/o tratamiento de enfermedades metabolicas de huesos, proceso para preparar tal composicion y el uso de la misma. |
KR20120065435A (ko) | 2002-05-10 | 2012-06-20 | 에프. 호프만-라 로슈 아게 | 골다공증 치료 및 예방용 비스포스폰산 |
CA2689504A1 (en) * | 2007-06-19 | 2008-12-24 | Albemarle Corporation | Processes for manufacturing bisphosphonic acids |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0162510B1 (en) * | 1984-04-30 | 1991-08-28 | THE PROCTER & GAMBLE COMPANY | Kit for use in the treatment of osteoporosis |
WO1992014474A1 (en) * | 1991-02-26 | 1992-09-03 | Norwich Eaton Pharmaceuticals, Inc. | Methods for the treatment of osteoporosis |
HUT68010A (en) * | 1991-12-17 | 1995-05-29 | Procter & Gamble Pharma | The use of bisphonates and parathyroid hormone for the treatment of osteoporosis |
DE69316013T2 (de) * | 1992-06-30 | 1998-07-09 | Procter & Gamble Pharma | Verwendung von phosphinate zur behandlung der osteoporose |
EP0600834A1 (en) * | 1992-11-30 | 1994-06-08 | Ciba-Geigy Ag | Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing |
US5366965A (en) * | 1993-01-29 | 1994-11-22 | Boehringer Mannheim Gmbh | Regimen for treatment or prophylaxis of osteoporosis |
-
1995
- 1995-12-27 AR AR33481795A patent/AR000555A1/es unknown
- 1995-12-27 CA CA002208714A patent/CA2208714C/en not_active Expired - Lifetime
- 1995-12-27 JP JP52021596A patent/JP3796693B2/ja not_active Expired - Lifetime
- 1995-12-27 ES ES95943216T patent/ES2262145T3/es not_active Expired - Lifetime
- 1995-12-27 DE DE69534923T patent/DE69534923T2/de not_active Expired - Lifetime
- 1995-12-27 EP EP95943216A patent/EP0800397B1/en not_active Expired - Lifetime
- 1995-12-27 BR BR9510123A patent/BR9510123A/pt not_active Application Discontinuation
- 1995-12-27 KR KR1019970704467A patent/KR100385697B1/ko not_active IP Right Cessation
- 1995-12-27 AU AU44347/96A patent/AU701258B2/en not_active Expired
- 1995-12-27 WO PCT/EP1995/005142 patent/WO1996019998A1/en active IP Right Grant
- 1995-12-28 ZA ZA9510995A patent/ZA9510995B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0800397A1 (en) | 1997-10-15 |
AU701258B2 (en) | 1999-01-21 |
ES2262145T3 (es) | 2006-11-16 |
CA2208714C (en) | 2003-10-21 |
DE69534923T2 (de) | 2006-11-23 |
DE69534923D1 (de) | 2006-05-18 |
CA2208714A1 (en) | 1996-07-04 |
JP3796693B2 (ja) | 2006-07-12 |
ZA9510995B (en) | 1997-06-30 |
BR9510123A (pt) | 1997-12-30 |
EP0800397B1 (en) | 2006-04-05 |
KR100385697B1 (ko) | 2003-08-21 |
JPH11502506A (ja) | 1999-03-02 |
WO1996019998A1 (en) | 1996-07-04 |
AU4434796A (en) | 1996-07-19 |
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FB | Suspension of granting procedure |