(Q46890625)

English

Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration.

scientific article published in January 2006

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16407564

Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

1 reference

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inferred from title

neurodegeneration

1 reference

based on heuristic

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Daniel Watterson

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

Linda J Van Eldik

6

object named as

Linda J Van Eldik

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

author name string

Hantamalala Ralay Ranaivo

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

Jeffrey M Craft

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

Wenhui Hu

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

Ling Guo

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

Laura K Wing

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

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publication date

1 January 2006

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16407564

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

26

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

662-670

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

Alzheimer neuropathologic alterations in aged cognitively normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening in a cell-based assay for inhibitors of microglial nitric oxide production reveals calmodulin-regulated protein kinases as potential drug discovery targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a 3-amino-6-phenyl-pyridazine derivative as a new synthetic antineuroinflammatory compound

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The double-edged sword of COX-2 selective NSAIDs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NSAIDs and Alzheimer's disease: how far to generalise from trials?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ApoE and Abeta1-42 interactions: effects of isoform and conformation on structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminopyridazines attenuate hippocampus-dependent behavioral deficits induced by human beta-amyloid in a murine model of neuroinflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminopyridazines inhibit beta-amyloid-induced glial activation and neuronal damage in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of inflammation in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The blood-brain barrier: bottleneck in brain drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced susceptibility of S-100B transgenic mice to neuroinflammation and neuronal dysfunction induced by intracerebroventricular infusion of human beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammation in the pathogenesis of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroscience. The dark side of glia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of the neuroinflammation cycle as a drug discovery target using integrative chemical biology and lead compound development with an Alzheimer's disease-related mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammation: a potential therapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human amyloid beta-induced neuroinflammation is an early event in neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

De novo and molecular target-independent discovery of orally bioavailable lead compounds for neurological disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition and metabolism of minaprine in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S100 beta expression in Alzheimer's disease: relation to neuropathology in brain regions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16407564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4652-05.2006

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674428&resulttype=core&format=json

11 May 2020

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