(Q35794580)

10 August 2017

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title

ApoE and Abeta1-42 interactions: effects of isoform and conformation on structure and function (English)

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10 August 2017

Linda J Van Eldik

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10 August 2017

Arlene M Manelli

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10 August 2017

W Blaine Stine

series ordinal

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10 August 2017

Mary Jo LaDu

series ordinal

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10 August 2017

language of work or name

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1 January 2004

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Journal of Molecular Neuroscience

10 August 2017

published in

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10 August 2017

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10 August 2017

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10 August 2017

page(s)

235-246

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Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

10 August 2017

cites work

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12 December 2020

Characterization of apolipoprotein J-Alzheimer's A beta interaction

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12 December 2020

Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid

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12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

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12 December 2020

Apolipoprotein E receptors mediate the effects of beta-amyloid on astrocyte cultures

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12 December 2020

Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures

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12 December 2020

Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.

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12 December 2020

Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease

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12 December 2020

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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12 December 2020

An honorable compromise regarding amyloid in Alzheimer disease.

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12 December 2020

Influence of lipoproteins on microglial degradation of Alzheimer's amyloid beta-protein

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12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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12 December 2020

Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro

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12 December 2020

Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

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12 December 2020

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

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12 December 2020

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

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12 December 2020

Aβ Deposition Is Associated with Neuropil Changes, but not with Overt Neuronal Loss in the Human Amyloid Precursor Protein V717F (PDAPP) Transgenic Mouse

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12 December 2020

Protofibrils, the unifying toxic molecule of neurodegenerative disorders?

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12 December 2020

Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.

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12 December 2020

Alzheimer's disease and apolipoprotein E-4 allele in an Amish population.

1 reference

12 December 2020

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

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12 December 2020

Apolipoprotein E and low-density lipoprotein binding and internalization in primary cultures of rat astrocytes: isoform-specific alterations

1 reference

12 December 2020

Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress

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12 December 2020

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

12 December 2020

Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

1 reference

12 December 2020

Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity

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12 December 2020

Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice.

1 reference

12 December 2020

Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E

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12 December 2020

Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma

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12 December 2020

Apolipoprotein E suppresses glial cell secretion of TNF alpha

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12 December 2020

The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

1 reference

12 December 2020

SP-40,40 is a constituent of Alzheimer's amyloid

1 reference

12 December 2020

Alzheimer A beta neurotoxicity: promotion by antichymotrypsin, ApoE4; inhibition by A beta-related peptides

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12 December 2020

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

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12 December 2020

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

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12 December 2020

Lipoprotein effects on Abeta accumulation and degradation by microglia in vitro

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12 December 2020

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

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12 December 2020

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

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12 December 2020

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

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12 December 2020

Attenuation of the neurotoxic effect of A beta amyloid peptide by apolipoprotein E.

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12 December 2020

ApoE protects cortical neurones against neurotoxicity induced by the non-fibrillar C-terminal domain of the amyloid-beta peptide

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12 December 2020

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

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12 December 2020

Association of human, rat, and rabbit apolipoprotein E with ?-amyloid

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12 December 2020

Cerebrovascular smooth muscle cells internalize Alzheimer amyloid beta protein via a lipoprotein pathway: implications for cerebral amyloid angiopathy

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12 December 2020

The Sixth International Conference on Alzheimer's disease, Amsterdam, The Netherlands, July 1998. The amyloid cascade hypothesis debate: emerging consensus on the role of A beta and amyloid in Alzheimer's disease

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12 December 2020

Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.

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12 December 2020

Competition of Abeta amyloid peptide and apolipoprotein E for receptor-mediated endocytosis.

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12 December 2020

Alzheimer's disease: genes, proteins, and therapy

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12 December 2020

Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production

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12 December 2020

Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease

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12 December 2020

Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.

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12 December 2020

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

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12 December 2020

The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease

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12 December 2020

Isoform-specific modulation by apolipoprotein E of the activities of secreted beta-amyloid precursor protein

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12 December 2020

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

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12 December 2020

Gene dose of the epsilon 4 allele of apolipoprotein E and disease progression in sporadic late-onset Alzheimer's disease.

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12 December 2020

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

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12 December 2020

Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response

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12 December 2020

Apolipoprotein E attenuates beta-amyloid-induced astrocyte activation.

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12 December 2020

Targeted Replacement of the Mouse Apolipoprotein E Gene with the Common Human APOE3 Allele Enhances Diet-induced Hypercholesterolemia and Atherosclerosis

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12 December 2020

Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner

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12 December 2020

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

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12 December 2020

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

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12 December 2020

Apolipoprotein E epsilon 2 allele promotes longevity and protects patients with Down's syndrome from dementia

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12 December 2020

Apolipoprotein E genotype and Alzheimer's disease in Hong Kong elderly Chinese

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12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses

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12 December 2020

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

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12 December 2020

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

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12 December 2020

Apolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease

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12 December 2020

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

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12 December 2020

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

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12 December 2020

Oligomerizaiton and fibril asssembly of the amyloid-beta protein.

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12 December 2020

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

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12 December 2020

Apolipoprotein E: risk factor for Alzheimer disease

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12 December 2020

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains

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12 December 2020

Apolipoprotein E gene expression in astrocytes: developmental pattern and regulation.

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12 December 2020

Isoform-specific binding of apolipoprotein E to beta-amyloid

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12 December 2020

Identifiers

DOI

10.1385/JMN:23:3:235

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Dimensions Publication ID

10 August 2017

1038713477

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