(Q42795736)

7 November 2017

title

Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms (English)

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7 November 2017

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7 November 2017

Makoto Otsu

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Noriko Gotoh

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Hiromitsu Nakauchi

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7 November 2017

Masafumi Onodera

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7 November 2017

Masashi Sanada

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7 November 2017

Takahiro Suzuki

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7 November 2017

Lee-Yung Shih

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7 November 2017

Satoshi Yamazaki

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7 November 2017

Azusa Tamura

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7 November 2017

Hiroaki Honda

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7 November 2017

Mamiko Sakata-Yanagimoto

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7 November 2017

Keiki Kumano

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7 November 2017

Hideaki Oda

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7 November 2017

Tetsuya Yamagata

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7 November 2017

Junko Takita

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7 November 2017

Kumi Nakazaki

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7 November 2017

Norihiko Kawamata

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7 November 2017

Masaharu Nobuyoshi

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7 November 2017

Yasuhide Hayashi

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7 November 2017

Hiroshi Harada

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7 November 2017

Mineo Kurokawa

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7 November 2017

Shigeru Chiba

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7 November 2017

Hiraku Mori

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7 November 2017

Keiya Ozawa

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7 November 2017

Mitsuhiro Omine

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7 November 2017

Hisamaru Hirai

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7 November 2017

H Phillip Koeffler

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7 November 2017

Seishi Ogawa

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7 November 2017

language of work or name

English

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publication date

20 July 2009

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7 November 2017

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7 November 2017

volume

460

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7 November 2017

issue

7257

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7 November 2017

page(s)

904-908

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Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

7 November 2017

cites work

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE08240

Gain of function mutations in p53.

21 January 2018

1 reference

12 December 2020

Feasibility of ex vivo gene therapy for neurological disorders using the new retroviral vector GCDNsap packaged in the vesicular stomatitis virus G protein

1 reference

12 December 2020

Oncogenic mutations of ALK kinase in neuroblastoma

1 reference

12 December 2020

c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses

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12 December 2020

Cbl: many adaptations to regulate protein tyrosine kinases

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12 December 2020

Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia

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12 December 2020

The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells

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12 December 2020

Flt3-dependent transformation by inactivating c-Cbl mutations in AML

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12 December 2020

A new red fluorescent protein that allows efficient marking of murine hematopoietic stem cells

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12 December 2020

The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif

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12 December 2020

The Cbl interactome and its functions

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12 December 2020

The p53 proto-oncogene can act as a suppressor of transformation

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12 December 2020

Exon 8 splice site mutations in the gene encoding the E3-ligase CBL are associated with core binding factor acute myeloid leukemias

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12 December 2020

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

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12 December 2020

c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation

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12 December 2020

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

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12 December 2020

Hematopoietic growth factors, signaling and the chronic myeloproliferative disorders

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12 December 2020

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

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12 December 2020

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

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12 December 2020

Potent vaccine therapy with dendritic cells genetically modified by the gene-silencing-resistant retroviral vector GCDNsap.

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12 December 2020

A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays

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12 December 2020

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

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12 December 2020

Myelodysplastic syndromes: the complexity of stem-cell diseases

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12 December 2020

Highly sensitive method for genomewide detection of allelic composition in nonpaired, primary tumor specimens by use of affymetrix single-nucleotide-polymorphism genotyping microarrays

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12 December 2020

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

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12 December 2020

Stable transgene expression in mice generated from retrovirally transduced embryonic stem cells

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12 December 2020

Acquired loss of p53 induces blastic transformation in p210(bcr/abl)-expressing hematopoietic cells: a transgenic study for blast crisis of human CML.

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12 December 2020

Cytogenetic features in myelodysplastic syndromes

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12 December 2020

Two genetic hits (more or less) to cancer

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12 December 2020

250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies

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12 December 2020

Adult mouse hematopoietic stem cells: purification and single-cell assays

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12 December 2020

Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl).

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12 December 2020

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

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12 December 2020

Regulating the regulator: negative regulation of Cbl ubiquitin ligases

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12 December 2020

Identifiers

DOI

10.1038/NATURE08240

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7 November 2017

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