(Q28241887)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

Annelise Bennaceur Griscelli

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Stefan N Constantinescu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Chloé James

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Valérie Ugo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Jean-Pierre Le Couédic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Judith Staerk

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Catherine Lacout

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Loïc Garçon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Roland Berger

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Nicole Casadevall

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

language of work or name

English

0 references

publication date

1 April 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

434

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

issue

7037

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

page(s)

1144-1148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

10 January 2020

cites work

1 reference

Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity

20 April 2017

1 reference

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

20 April 2017

1 reference

The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor

20 April 2017

1 reference

Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor

20 April 2017

1 reference

The chronic myeloproliferative disorders: clonality and clinical heterogeneity

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Polycythemia vera and other primary polycythemias

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Polycythemia vera: myths, mechanisms, and management

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Exploring polycythaemia vera with fluorescence in situ hybridization: additional cryptic 9p is the most frequent abnormality detected

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Clonal hematopoiesis in familial polycythemia vera suggests the involvement of multiple mutational events in the early pathogenesis of the disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Regulation of the Jak2 tyrosine kinase by its pseudokinase domain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Genomic organization of human JAK2 and mutation analysis of its JH2-domain in leukemia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Partial chromosome 21 amplification in a child with acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Stimulation of osteoprotegerin production is responsible for osteosclerosis in mice overexpressing TPO.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03546

7 January 2021

Identifiers

DOI

10.1038/NATURE03546

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 January 2020

1041406511

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15793561%20AND%20SRC:MED&resulttype=core&format=json