(Q24621898)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

0 references

1 reference

1 reference

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20 January 2020

Karen H Vousden

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Hao Dou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Lori Buetow

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Andreas Hock

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Gary J Sibbet

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

22 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

20 January 2020

published in

1 reference

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20 January 2020

volume

1 reference

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20 January 2020

issue

1 reference

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20 January 2020

page(s)

184-192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

20 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3880865/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

7 April 2017

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Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates

7 April 2017

1 reference

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Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling

7 April 2017

1 reference

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Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

7 April 2017

1 reference

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Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

7 April 2017

1 reference

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Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

7 April 2017

1 reference

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Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins

7 April 2017

1 reference

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Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases

7 April 2017

1 reference

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Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

7 April 2017

1 reference

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APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration

7 April 2017

1 reference

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Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment

7 April 2017

1 reference

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Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

7 April 2017

https://api.crossref.org/works/10.1038/NSMB.2231

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

22 April 2017

1 reference

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RING domain E3 ubiquitin ligases

7 April 2017

1 reference

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7 April 2017

1 reference

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The Cbl interactome and its functions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Ubiquitin: structures, functions, mechanisms

7 April 2017

1 reference

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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

7 April 2017

1 reference

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Structural regulation of cullin-RING ubiquitin ligase complexes

7 April 2017

1 reference

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Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia

27 September 2017

1 reference

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The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme

27 September 2017

1 reference

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Cbl and human myeloid neoplasms: the Cbl oncogene comes of age.

27 September 2017

1 reference

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Cbl controls EGFR fate by regulating early endosome fusion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

c-Cbl-mediated degradation of TRAIL receptors is responsible for the development of the early phase of TRAIL resistance.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

27 September 2017

1 reference

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Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail

27 September 2017

1 reference

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The Cbl family proteins: ring leaders in regulation of cell signaling

27 September 2017

1 reference

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Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Regulating the regulator: negative regulation of Cbl ubiquitin ligases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Structural model of the UbcH5B/CNOT4 complex revealed by combining NMR, mutagenesis, and docking approaches.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Autoinhibitory domains: modular effectors of cellular regulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Isolation and characterization of a novel, transforming allele of the c-Cbl proto-oncogene from a murine macrophage cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Protein interactions within the N-end rule ubiquitin ligation pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880865

Structural mechanisms underlying posttranslational modification by ubiquitin-like proteins

28 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2231

31 March 2020

Identifiers

DOI

10.1038/NSMB.2231

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 January 2020

1030223477

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

22266821

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266821%20AND%20SRC:MED&resulttype=core&format=json