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Signal transduction interfaces for field-effect transistor-based biosensors
Biosensors based on field-effect transistors (FETs) are suitable for use in miniaturized and cost-effective healthcare devices. Various...
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Transcription Factors and Signal Transduction
In this chapter, we will present transcription factors as the key controllers of gene expression. The activities of these proteins critically...
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Signal transduction in plant cold acclimation
Temperate plants respond to low temperature by activating a cold acclimation program leading to enhanced tolerance to freezing temperatures. This...
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Thermodynamics of signal transduction systems and fluctuation theorem in a signal cascade
Biochemical chain reactions are signal transduction cascades that can transmit biological information about the intracellular environment. In this...
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Channel capacity: limitation of entropy rate during cell signal transduction
Cellular signal transduction is mediated through chain activation reactions involving signalling molecules. Information thermodynamics may be a...
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O-GlcNAc and Signal Transduction in Cancer
Protein O-GlcNAcylation is of essential importance as an integrator of signal transduction networks involved in almost all cellular processes....
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ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction
Z-DNA binding protein 1 (ZBP1) is a crucial player in the intracellular recognition of Z-form nucleic acids (Z-NAs) through its Zαβ domain,...
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The implications of alternative pre-mRNA splicing in cell signal transduction
Cells produce multiple mRNAs through alternative splicing, which ensures proteome diversity. Because most human genes undergo alternative splicing,...
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Investigations on Signal Transduction Processes Utilizing Small Chemical Probes
This book presents a major research program investigating signal transduction processes utilizing small molecule compound probes. The program was...
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LATS2 condensates organize signalosomes for Hippo pathway signal transduction
Biomolecular condensates have been proposed to mediate cellular signaling transduction. However, the mechanism and functional consequences of signal...
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Molecular mechanisms underlying the signal perception and transduction during seed germination
QuerySeed germination is a vital step in the life cycle of a plant, playing a significant role in seedling establishment and crop yield potential. It...
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Free Radicals and Signal Transduction in Cells
AbstractThis review provides an overview of molecular mechanisms of intracellular signal transduction involving free radicals. The structure and...
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Signal Perception and Transduction Mechanisms
While investigating the effect of unilateral light on the bending response of canary grass (Phalaris canariensis) seedlings, Charles Darwin (1881)...
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Self-consistent signal transduction analysis for modeling context-specific signaling cascades and perturbations
Biological signal transduction networks are central to information processing and regulation of gene expression across all domains of life....
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Programming conformational cooperativity to regulate allosteric protein-oligonucleotide signal transduction
Conformational cooperativity is a universal molecular effect mechanism and plays a critical role in signaling pathways. However, it remains a...
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Transcription Factors and Signal Transduction
In this chapter, we will present transcription factors as the key controllers of gene expression. The activities of these proteins critically...
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Assessing Onsager’s reciprocity difference in signal transduction cascade model: a new metric for evaluating cellular response dynamics
The cell signaling system translates extracellular changes into biochemical reactions within the cell, ultimately affecting gene expression. This...
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Information Processing in Calcium Signal Transduction
Calcium signalling often employs calcium oscillations. It is by now a well-known fact that information, e.g. about the amount of stimulus that evoked...
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Signal Transduction and Enzymatic Metabolic Reactions in Living Organisms
Protein structures are flexible and can change conformation dynamically, allowing them to perform a wide variety of functions. This allows for...