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Embryonic Stem Cell Protocols
This fully updated volume explores improved and extended protocols for embryonic stem cell (ESC) research, provided with the most direct and...
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Rat Embryonic Stem Cell Transgenesis
The availability of reliable germline competent rat embryonic stem cell (ESC) lines that can be genetically manipulated provides an important tool...
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Quiescence enables unrestricted cell fate in naive embryonic stem cells
Quiescence in stem cells is traditionally considered as a state of inactive dormancy or with poised potential. Naive mouse embryonic stem cells...
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RNA-Mediated Regulation of Glycolysis in Embryonic Stem Cell Pluripotency and Differentiation
Purpose of ReviewThe maintenance and differentiation of embryonic stem cells are strictly coordinated with their metabolic status. As a core part of...
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Handbook of Stem Cell Applications
This handbook reviews the clinical applications of stem cell-based therapy. The book covers the clinical applications of stem cells in cardiovascular...
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Assembly of complete mouse embryo models from embryonic and induced stem cell types in vitro
The interaction between embryonic and extraembryonic tissues is critical in natural mouse embryogenesis. Here, to enable such interaction in vitro,...
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The effect of nanomaterials on embryonic stem cell neural differentiation: a systematic review
BackgroundHumans’ nervous system has a limited ability to repair nerve cells, which poses substantial challenges in treating injuries and diseases....
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Histogenesis of intracranial germ cell tumors: primordial germ cell vs. embryonic stem cell
IntroductionIntracranial germ cell tumor (iGCT) is a rare disorder and often occurs during childhood and adolescence. iGCTs are frequently localized...
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Stem Cell Exhaustion
In a lifetime, several insults occur in human tissues and therefore, the regenerative and repair processes play a crucial role maintaining tissue...
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Embryonic Stem Cells and the ‘Last-Minute’ Correction
Embryonic stem cells (ESCs)Embryonic stem cells (ESCs) are the totipotent/pluripotent stem cellsPluripotent stem cells which initiate formation of a...
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Handbook of Stem Cell Applications
This handbook reviews the clinical applications of stem cell-based therapy. The book covers the clinical applications of stem cells in cardiovascular...
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Development and application of haploid embryonic stem cells
Haploid cells are a kind of cells with only one set of chromosomes. Compared with traditional diploid cells, haploid cells have unique advantages in...
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A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs
Animal-based test systems have traditionally been used to screen for the potential teratogenic activity of drugs. Still, their deficits in predicting...
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MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner
H3K4me1 methyltransferases MLL3 (KMT2C) and MLL4 (KMT2D) are critical for enhancer activation, cell differentiation and development. However, roles...
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Embryonic-stem-cell-derived mesenchymal stem cells relieve experimental contact urticaria by regulating the functions of mast cells and T cells
Contact urticaria (CU) is an inflammatory skin disorder triggered by specific substances upon skin contact, leading to immediate acute or chronic...
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Derivation of Bovine Primed Embryonic Stem Cells from Somatic Cell Nuclear Transfer Embryos
Derivation of bovine embryonic stem cells from somatic cell nuclear transfer embryos enables the derivation of genetically matched pluripotent stem...
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Zyxin regulates embryonic stem cell fate by modulating mechanical and biochemical signaling interface
Biochemical signaling and mechano-transduction are both critical in regulating stem cell fate. How crosstalk between mechanical and biochemical cues...
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The Epiblast and Pluripotent Stem Cell Lines
All somatic cells develop from the epiblast, which occupies the upper layer of two-layered embryos and in most mammals is formed after the...
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Haspin balances the ratio of asymmetric cell division through Wnt5a and regulates cell fate decisions in mouse embryonic stem cells
Many different types of stem cells utilize asymmetric cell division (ACD) to produce two daughter cells with distinct fates. Haspin-catalyzed...
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Pig blastocyst-like structure models from embryonic stem cells
Pluripotent stem cells have the potential to generate embryo models that can recapitulate developmental processes in vitro. Large animals such as...
