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A taste for hot sauce

October 8, 2024

A taste for hot sauce

Can positive and negative expectations of a sensory experience cause neuronal and perception differences? Yi Luo, Kenneth Kishida and colleagues show that sensory experiences and neuronal responses are shaped by whether a person likes spicy foods, suggesting that perception could be pharmacologically modulated.

Image credit: pbio.3002818 & Unsplash user Robin Thang

PLOS Biologue

Community blog for PLOS Biology, PLOS Genetics and PLOS Computational Biology.

PLOS BIOLOGUE

10/09/2024

Research Article

Unifying statistical genetics and phylogenetics

Statistical genetics and phylogenetics have different methods of finding associations with phenotypes while controlling for ancestry. Joshua Schraiber, Michael Edge and Matt Pennell show that the standard approaches in these fields are actually special cases of the same general approach, enabling more integrative future studies.

Image credit: pbio.3002847

Unifying statistical genetics and phylogenetics

Recently Published Articles

Current Issue

Current Issue September 2024

10/08/2024

Preregistered Research Article

15 weeks in the life of a brain

Functional brain activity is often measured during a single scanning session which neglects behavioral, physiological and lifestyle effects on brain activity. Ana MarĂ­a Triana, Enrico Glerean and co-workers present functional neuroimaging data from 30 neuroimaging sessions across 15 weeks from one participant, revealing relationships between human daily behavior and brain function under different stimuli.

Image credit: pbio.3002797

15 weeks in the life of a brain

10/07/2024

Research Article

Counting leg muscles

Communication between different cell lineages is crucial for the formation of functional organs. Blandine Moucaud, Cedric Soler and co-authors identify Amalgam and Neurotactin as essential players that mediate early reciprocal communication between leg muscle and tendon precursors to coordinate the development of the Drosophila leg.

Image credit: pbio.3002842

Counting leg muscles

10/04/2024

Research Article

Reviving collapsed ecological networks

How can we revive a collapsed mutualistic ecological network? Gaurav Baruah and Meike Wittmann use concepts from signal propagation theory and an eco-evolutionary model based on network structures of 115 empirical plant-pollinator networks to reveal that effort should be focused on one or a few key species.

Reviving collapsed ecological networks

Image credit: pbio.3002826

10/03/2024

Research Article

Basis of auditory hallucinations

Can the absence of inhibition lead to auditory hallucinations? Fuyin Yang, Chen Zhang, Xing Tian and co-authors show that the impairment of motor-based sensory predictions causes erroneous monitoring of imprecise internal auditory representations, thus causing auditory hallucinations.

Basis of auditory hallucinations

Image credit: pbio.3002836

10/03/2024

Research Article

Packaging viral RNA genomes

The role of long-range interactions (LRI) in retroviral RNA packaging is unclear. Suresha Prabhu, Roland Marquet, Tahir Rizvi and colleagues reveal that a specific packaging signal (Psi) structure, maintained by an extended LRI, is crucial for efficient packaging of the mouse mammary tumor virus (MMTV) RNA genome, with Gag binding to key Psi sites essential for selectivity.

Packaging viral RNA genomes

Image credit: pbio.3002827

09/19/2024

Perspective

Reusable methods and protocols (PRO-MaP)

This Perspective article describes PRO-MaP, which aims to increase and improve the reporting of detailed, structured and open methods and reusable step-by-step protocols in the life sciences.

Reusable methods and protocols (PRO-MaP)

Image credit: European Union

09/16/2024

Consensus View

New nomenclature for dengue virus

There is currently no suitable system to classify circulating dengue virus (DENV) variants. This Consensus View proposes a new nomenclature system and free online tools to identify and track lineages of potential epidemiological and/or clinical importance.

New nomenclature for dengue virus

Image credit: pbio.3002834

09/10/2024

Essay

Code sharing in biology

For those who want to share their code but don't know where to start, this Essay distils dozens of articles on reproducibility and research software, collecting the most important practical details of how to provide computational transparency even if you aren't a trained software developer.

Code sharing in biology

Image credit: pbio.3002815

09/09/2024

Perspective

Fixing science: stop gaming the system

The open science movement has gained ground, but improvements to the practice of science move at a glacial pace. This Perspective explores the misaligned incentives that are hindering progress to more open, reproducible research.

Fixing science: stop gaming the system

Image credit: Pixabay user PIRO4D

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