... Haghighati F, Jafari S, Momen Beitollahi J. Comparison of antimicrobial effects of ten Herbal... more ... Haghighati F, Jafari S, Momen Beitollahi J. Comparison of antimicrobial effects of ten Herbal extracts with chlorhexidine on three different oral pathogens; an in vitro study. ... Mohammadmahdi Yaghooti Khorasani*, Sepideh Assar, Omid Rezahosseini, Shokrollah Assar Abstract ...
Antepartum mastitis is a rare condition, whereas postpartum orlactation mastitis is a common prob... more Antepartum mastitis is a rare condition, whereas postpartum orlactation mastitis is a common problem. This report introducesa case of complicated bilateral antepartum mastitis, which wastreated successfully by drain insertion and antibiotic therapy.The patient was a 23-year-old woman in the 23rd week of herfirst pregnancy. Her chief complaint was progressive swelling,redness and radicular pain in both breasts, which had beenstarted gradually from the 18th week of pregnancy. The patientwas admitted to hospital, and received oral and intravenous antibioticsempirically, which was not effective. The patient wastreated by drainage and oral antibiotic therapy. Based on theapproaches employed and the outcomes achieved it is suggestedthat early surgical insertion in the presence of fluid collection inantepartum mastitis will shorten hospitalization and course ofintravenous antibiotic therapy.Iran J Med Sci 2010; 35(4): 327-330.
Introduction & Aim: streptococcus mutans and streptococcus sanguis are infectious agents which ha... more Introduction & Aim: streptococcus mutans and streptococcus sanguis are infectious agents which have a role in plaque formation and result tooth decay. Usage of appropriate mouthwash can destroy or inhibit the growth of these bacteria and other microorganisms. As increasing the dilution of mouthwashes can reduce their probable side effects, so in this study we surveyed the maximum inhibitory dilution of two highly applicable mouthwashes ( chlorehexidine and thimol based mouthwashes). Materials & Methods: for each used mouthwash, we prepared 20 solution with intervals of 5 percent in distilled water and added them into Mueller Hinton agar culture medium, which is a suitable and enriched medium for bacterial growth. After homogenization, the culture medium was poured onto Petri dishes, and for each dilution, 3 plates were considered. All the plates were incubated 24 hours in 37 centigrade degrees. To surveying growth inhibitory dilution, formed colonies studied in or on the culture med...
Objective: The present study aimed to determine the frequency of drug abused in a sample of unive... more Objective: The present study aimed to determine the frequency of drug abused in a sample of university students in Rafsanjan, Iran. Methods: In this cross-sectional study, 1,260 students volunteered (311 males and 949 females) with mean age of 21.35 years. Data were collected by a self-administrated questionnaire regarding drugs abuse and demographic information. Results: Benzodiazepines were the most common abused drugs which were reported in 94 students (7.4%). Other agents studied were cigarette and tobacco (159, cases 12.6%), alcoholic drinks (60 cases, 4.7%), and opiates (42 cases, 3.3%). Forty-three students (3.4%) had used methylphenidate in the last 6 months. Of this, 39 (90.6%) experienced insomnia. All students who abused methylphenidate indicated that the reason for this behavior was to raise alertness and conscious levels. Conclusion: The pattern of drug abuse among the students here seems similar to other reports from Iranian universities.
Iranian journal of psychiatry and behavioral sciences, 2014
The present study aimed to determine the frequency of drug abused in a sample of university stude... more The present study aimed to determine the frequency of drug abused in a sample of university students in Rafsanjan, Iran. In this cross-sectional study, 1,260 students volunteered (311 males and 949 females) with mean age of 21.35 years. Data were collected by a self-administrated questionnaire regarding drugs abuse and demographic information. Benzodiazepines were the most common abused drugs which were reported in 94 students (7.4%). Other agents studied were cigarette and tobacco (159, cases 12.6%), alcoholic drinks (60 cases, 4.7%), and opiates (42 cases, 3.3%). Forty-three students (3.4%) had used methylphenidate in the last 6 months. Of this, 39 (90.6%) experienced insomnia. All students who abused methylphenidate indicated that the reason for this behavior was to raise alertness and conscious levels. The pattern of drug abuse among the students here seems similar to other reports from Iranian universities.
Escape mutations potentially allow viruses to avoid detection and clearance by the host immune sy... more Escape mutations potentially allow viruses to avoid detection and clearance by the host immune system and may represent a mechanism through which infections may persist in some patients. The association of the mutations in the HBcAg gene with Hepatitis B asymptomatic carriers (ASC) has not been studied adequately. The current study was aimed to investigate HBcAg18-27 CTL epitope mutations in ASC patients in the South-Eastern region of Iran. 100 ASC patients were selected for this study and screened for HLA-A2 using flow cytometry. HBV-DNA was extracted from the HLA-A2 positive patients and the HBc gene was amplified using PCR. Direct double sequencing was performed to analyse mutations in the HBc gene of HBV isolates from patients with ASC. Overall, 25 (25%) of individuals were HLA-A2 positive. Direct double sequencing indicated no mutations in the HBcAg18-27 epitope. However, four mutations within the T helper and three mutations within the B cell epitopes of ASC patients were iden...
Introduction: There is a chemokine-receptor network an immune cells (mast cells, eosinophils) in ... more Introduction: There is a chemokine-receptor network an immune cells (mast cells, eosinophils) in asthma. MIP-1 (CCL3), MIP-1 (CCL4) and RANTES (CCL5) are among important chemokines which one involved in pathogenesis of asthma. These chemokines bind to CCR5 on target cells. CCR5 play important role in pathogenesis of asthma, hence, this study aimed analysis 32 mutation in CCR5 in asthmatic patients. Material and methods: this experimental study was performed on 81 asthmatic patients and 200 healthy controls during February to June 2008 in Rafsanjan University of Medical Sciences. The Gap-PCR was applied for analysis 32 mutation in CCR5 gene and demographic information (age, sex, occupation, socio-economic status and etc) were collected by questionnaire. Results: Finding of this study indicated that none of asthmatic patients had 32 mutation in CCR5 chemokine receptor while 3 (1.5%) of controls cases showed heterozigotic form of this mutation. Discussion: Several research grou...
Background: Cytotoxic effects of Frankincense resin have been shown on some cancer cell lines. Du... more Background: Cytotoxic effects of Frankincense resin have been shown on some cancer cell lines. Due to its low side effects, this study was designed to evaluate the anticancer properties of water soluble elements of Frankincense oleo-gum-resin on human oral squamous cell carcinoma cell line. Methods: Oleo-gum-resin was macerated in ethanol. After filtration, the water soluble fraction of dried residue was extracted. KB cells were treated with 0, 62.5, 125, 250 and 500 µg/mL concentrations of obtained Frankincense aqueous fractions and with Doxorubicin as positive control. Frankincense induced cell cytotoxicity; apoptosis and proliferation were investigated using WST assay, Annexin V-FITC/PI, and Ki-67 staining, respectively. Data were analyzed using Kruskal-Wallis test by SPSS 17 software. Results: IC50 of 137.21 µg/mL was obtained from Frankincense aqueous fraction after 48 hours. The percentage of apoptotic cells was elevated in a time-and dose-dependent manner. There was no statistical difference in the Ki-67 expression of KB cells, using different concentration of Frankincense aqueous fraction after 24 and 48 hours (P = 0.083). Doxorubicin inhibited cells growth essentially through apoptosis. Conclusions: Frankincense aqueous fractions seem to suppress KB cell growth through the induction of apoptosis and necrosis rather than the inhibition of proliferation and hence might be a potential anticancer agent. Structural analysis and purification of potent components are suggested for determining more definitive results.
... Haghighati F, Jafari S, Momen Beitollahi J. Comparison of antimicrobial effects of ten Herbal... more ... Haghighati F, Jafari S, Momen Beitollahi J. Comparison of antimicrobial effects of ten Herbal extracts with chlorhexidine on three different oral pathogens; an in vitro study. ... Mohammadmahdi Yaghooti Khorasani*, Sepideh Assar, Omid Rezahosseini, Shokrollah Assar Abstract ...
Antepartum mastitis is a rare condition, whereas postpartum orlactation mastitis is a common prob... more Antepartum mastitis is a rare condition, whereas postpartum orlactation mastitis is a common problem. This report introducesa case of complicated bilateral antepartum mastitis, which wastreated successfully by drain insertion and antibiotic therapy.The patient was a 23-year-old woman in the 23rd week of herfirst pregnancy. Her chief complaint was progressive swelling,redness and radicular pain in both breasts, which had beenstarted gradually from the 18th week of pregnancy. The patientwas admitted to hospital, and received oral and intravenous antibioticsempirically, which was not effective. The patient wastreated by drainage and oral antibiotic therapy. Based on theapproaches employed and the outcomes achieved it is suggestedthat early surgical insertion in the presence of fluid collection inantepartum mastitis will shorten hospitalization and course ofintravenous antibiotic therapy.Iran J Med Sci 2010; 35(4): 327-330.
Introduction & Aim: streptococcus mutans and streptococcus sanguis are infectious agents which ha... more Introduction & Aim: streptococcus mutans and streptococcus sanguis are infectious agents which have a role in plaque formation and result tooth decay. Usage of appropriate mouthwash can destroy or inhibit the growth of these bacteria and other microorganisms. As increasing the dilution of mouthwashes can reduce their probable side effects, so in this study we surveyed the maximum inhibitory dilution of two highly applicable mouthwashes ( chlorehexidine and thimol based mouthwashes). Materials & Methods: for each used mouthwash, we prepared 20 solution with intervals of 5 percent in distilled water and added them into Mueller Hinton agar culture medium, which is a suitable and enriched medium for bacterial growth. After homogenization, the culture medium was poured onto Petri dishes, and for each dilution, 3 plates were considered. All the plates were incubated 24 hours in 37 centigrade degrees. To surveying growth inhibitory dilution, formed colonies studied in or on the culture med...
Objective: The present study aimed to determine the frequency of drug abused in a sample of unive... more Objective: The present study aimed to determine the frequency of drug abused in a sample of university students in Rafsanjan, Iran. Methods: In this cross-sectional study, 1,260 students volunteered (311 males and 949 females) with mean age of 21.35 years. Data were collected by a self-administrated questionnaire regarding drugs abuse and demographic information. Results: Benzodiazepines were the most common abused drugs which were reported in 94 students (7.4%). Other agents studied were cigarette and tobacco (159, cases 12.6%), alcoholic drinks (60 cases, 4.7%), and opiates (42 cases, 3.3%). Forty-three students (3.4%) had used methylphenidate in the last 6 months. Of this, 39 (90.6%) experienced insomnia. All students who abused methylphenidate indicated that the reason for this behavior was to raise alertness and conscious levels. Conclusion: The pattern of drug abuse among the students here seems similar to other reports from Iranian universities.
Iranian journal of psychiatry and behavioral sciences, 2014
The present study aimed to determine the frequency of drug abused in a sample of university stude... more The present study aimed to determine the frequency of drug abused in a sample of university students in Rafsanjan, Iran. In this cross-sectional study, 1,260 students volunteered (311 males and 949 females) with mean age of 21.35 years. Data were collected by a self-administrated questionnaire regarding drugs abuse and demographic information. Benzodiazepines were the most common abused drugs which were reported in 94 students (7.4%). Other agents studied were cigarette and tobacco (159, cases 12.6%), alcoholic drinks (60 cases, 4.7%), and opiates (42 cases, 3.3%). Forty-three students (3.4%) had used methylphenidate in the last 6 months. Of this, 39 (90.6%) experienced insomnia. All students who abused methylphenidate indicated that the reason for this behavior was to raise alertness and conscious levels. The pattern of drug abuse among the students here seems similar to other reports from Iranian universities.
Escape mutations potentially allow viruses to avoid detection and clearance by the host immune sy... more Escape mutations potentially allow viruses to avoid detection and clearance by the host immune system and may represent a mechanism through which infections may persist in some patients. The association of the mutations in the HBcAg gene with Hepatitis B asymptomatic carriers (ASC) has not been studied adequately. The current study was aimed to investigate HBcAg18-27 CTL epitope mutations in ASC patients in the South-Eastern region of Iran. 100 ASC patients were selected for this study and screened for HLA-A2 using flow cytometry. HBV-DNA was extracted from the HLA-A2 positive patients and the HBc gene was amplified using PCR. Direct double sequencing was performed to analyse mutations in the HBc gene of HBV isolates from patients with ASC. Overall, 25 (25%) of individuals were HLA-A2 positive. Direct double sequencing indicated no mutations in the HBcAg18-27 epitope. However, four mutations within the T helper and three mutations within the B cell epitopes of ASC patients were iden...
Introduction: There is a chemokine-receptor network an immune cells (mast cells, eosinophils) in ... more Introduction: There is a chemokine-receptor network an immune cells (mast cells, eosinophils) in asthma. MIP-1 (CCL3), MIP-1 (CCL4) and RANTES (CCL5) are among important chemokines which one involved in pathogenesis of asthma. These chemokines bind to CCR5 on target cells. CCR5 play important role in pathogenesis of asthma, hence, this study aimed analysis 32 mutation in CCR5 in asthmatic patients. Material and methods: this experimental study was performed on 81 asthmatic patients and 200 healthy controls during February to June 2008 in Rafsanjan University of Medical Sciences. The Gap-PCR was applied for analysis 32 mutation in CCR5 gene and demographic information (age, sex, occupation, socio-economic status and etc) were collected by questionnaire. Results: Finding of this study indicated that none of asthmatic patients had 32 mutation in CCR5 chemokine receptor while 3 (1.5%) of controls cases showed heterozigotic form of this mutation. Discussion: Several research grou...
Background: Cytotoxic effects of Frankincense resin have been shown on some cancer cell lines. Du... more Background: Cytotoxic effects of Frankincense resin have been shown on some cancer cell lines. Due to its low side effects, this study was designed to evaluate the anticancer properties of water soluble elements of Frankincense oleo-gum-resin on human oral squamous cell carcinoma cell line. Methods: Oleo-gum-resin was macerated in ethanol. After filtration, the water soluble fraction of dried residue was extracted. KB cells were treated with 0, 62.5, 125, 250 and 500 µg/mL concentrations of obtained Frankincense aqueous fractions and with Doxorubicin as positive control. Frankincense induced cell cytotoxicity; apoptosis and proliferation were investigated using WST assay, Annexin V-FITC/PI, and Ki-67 staining, respectively. Data were analyzed using Kruskal-Wallis test by SPSS 17 software. Results: IC50 of 137.21 µg/mL was obtained from Frankincense aqueous fraction after 48 hours. The percentage of apoptotic cells was elevated in a time-and dose-dependent manner. There was no statistical difference in the Ki-67 expression of KB cells, using different concentration of Frankincense aqueous fraction after 24 and 48 hours (P = 0.083). Doxorubicin inhibited cells growth essentially through apoptosis. Conclusions: Frankincense aqueous fractions seem to suppress KB cell growth through the induction of apoptosis and necrosis rather than the inhibition of proliferation and hence might be a potential anticancer agent. Structural analysis and purification of potent components are suggested for determining more definitive results.
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