Research Interests: Chemistry, Kinetics, Biology, Medicine, Insecticides, and 15 moreAnimals, Fishes, Acetylcholinesterase, Organophosphorus Compounds, Cholinesterase inhibitors, Enzyme, Organophosphate, In Vivo, Age Factors, Lethal Dose, Diazinon, Embryos, Metabolite, Aché, and Pharmacology and pharmaceutical sciences
Research Interests:
Research Interests:
Research Interests: Chemistry, Kinetics, Enzyme Inhibitors, Medicine, Brain, and 15 moreAnimals, Biochemical, Partition Coefficient, Solubility, Active site, Degeneration, Lipophilicity, Peripheral Nerve, BIOCHEMICAL PHARMACOLOGY, Membrane Protein, Detergents, Paraoxon, ketones, Chick embryo, and Pharmacology and pharmaceutical sciences
Research Interests:
The distribution of acetylcholinesterase (AChE) in oncospheres and developing cysticercoids of Hymenolepis diminuta was examined. The enzyme was localized in the nervous system and in some non-nerve cells of these larvae. In oncospheres... more
The distribution of acetylcholinesterase (AChE) in oncospheres and developing cysticercoids of Hymenolepis diminuta was examined. The enzyme was localized in the nervous system and in some non-nerve cells of these larvae. In oncospheres AChE was detected in hook muscles and in the binucleated medullar center that is known to enclose two neurons. At early developmental stages of the cysticercoids the enzyme was localized in the post-oncospheral hook muscles and in subtegumental muscle fibers of the cercomer. At medium and late stages of development the activity of AChE was detected in the developing nervous system and in two and, subsequently, in four populations of cells, which gradually spread over the whole internal wall of the cyst, thus forming a thin multilayer AChE-positive lining of the cyst cavity. Following withdrawal of the scolex the lining separates the parenchyma of the turned neck from the cyst tissues and remains AChE-positive during the whole life of the parasite, i....