Orthobunyavirus Ultrastructure and the Curious Tripodal Glycoprotein Spike
Figure 5
Low-pH induced structural rearrangements of glycoprotein spikes.
(A and B) The first four class averages of glycoprotein spikes in neutral (pH 7.4) and acidic (pH 5.1) buffers are shown in panels A and B, respectively (all class averages are displayed in Figure S6). (C) Schematic illustration of pH-induced loss of order in the stalk and head domains of BUNV spike. Gn is colored green, Gc brown, transmembrane regions blue, and membrane gray.