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Modulation of functional activity and connectivity by acupuncture in patients with Alzheimer disease as measured by resting-state fMRI

Fig 2

(A and B). Between-group differences in AD and HC before acupuncture, based on a 2-sample t test with age, gender, education level and mean FDR as covariates. The threshold was set to P < 0.001 with topo FDR corrected. The color scale represents t values. Cold color represents decreased ALFF in AD patients compared to HC. AD, Alzheimer’s disease; HC, healthy control; ALFF, amplitude of low-frequency fluctuations.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0196933.g002